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Neuroretinitis: Update on a visual emergency and role of technology in its diagnosis

Journal of Biomedical Science and Engineering 2013年第10期6卷 15-19页

作者： Subashini Kaliaperumal sunil narayan Department of Neurology Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry India Department of Ophthalmology Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry India

Neuroretinitis is one of the forms of optic neuritis characterized by swelling of optic nerve head and adjoining retinal nerve fiber layer resulting in a macular star configuration. The underlying pathophysiology involves increased permeability of disc vasculature, but the etiology is not fully defined. Neuroretinitis may occur due to an infectious process involving the disc, a postviral or autoimmune mechanism or sometimes idiopathic. Technological advances like ophthalmoscopy, slit-lamp examination, fluorescein angiography, magnetic resonance imaging and immunodiagnostic tests all come handily and are often imperative in making an accurate diagnosis. Conditions mimicking neuroretinitis include papilledema, anterior ischemic optic neuropathy, and infiltration of the optic disc by tumor and systemic hypertension. Neuroretinitis is usually a self-limited disorder with a good visual prognosis. Treatment of neuroretinitis is required only when there is an underlying infectious or inflammatory condition.

关键词： Neuroretinitis Macular Star Ophthalmoscopy Slit-Lamp Fluorescein Angiography Magnetic Resonance Imaging

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Preclinical animal studies in ischemic stroke:Challenges and some solutions

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Animal Models and Experimental Medicine 2021年第2期4卷 104-115页

作者： sunil K.narayan Simy Grace Cherian Prakash Babu Phaniti Saravana Babu Chidambaram A.Hannah Rachel Vasanthi Murugesan Arumugam Comprehensive Stroke Care and Neurobiology Centre Department of NeurologyJawaharlal Institute of Postgraduate Medical Education and ResearchPuducherryIndia Department of Biotechnology&School of Medical Sciences University of HyderabadHyderabadIndia Department of Pharmacology JSS Medical CollegeMysoreIndia Department of Biotechnology School of Life scienceUniversity of PondicherryPondicherryIndia

Despite the impressive efficacies demonstrated in preclinical research,hundreds of potentially neuroprotective drugs have failed to provide effective neuroprotec-tion for ischemic stroke in human clinical *** of a powerful animal model for human ischemic stroke could be a major reason for the failure to develop successful neuroprotective drugs for ischemic *** review recapitulates the available cerebral ischemia animal models,provides an anatomical comparison of the circle of Willis of each species,and describes the functional assessment tests used in these ischemic stroke *** distinct differences between human ischemic stroke and experimental stroke in available animal models is *** animal models more closely resembling human strokes,better techniques in functional out-come assessment and better experimental designs generating clearer and stronger evidence may help realise the development of truly neuroprotective drugs that will benefit human ischemic stroke *** may involve use of newer molecules or revisiting earlier studies with new experimental *** of any resultant successes may then be tested in human clinical trials with greater confidence and optimism.

关键词： cerebral ischemia circle of Willis focal ischemic models functional assessment tests neuroprotection preclinical model

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Wireless Sensor Enabled Public Transportation System

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International Journal of Communications, Network and System Sciences 2015年第5期8卷 187-196页

作者： sunil Praneel narayan Mansour H. Assaf Shalvindra Krishneel Prasad School of Engineering and Physics University of South Pacific Suva Fiji Pace Technologies Ltd Nadi Fiji

Automatic Vehicle Identification (AVI) in real time is becoming an urgent necessity due to rapid increase in the number of vehicles on roads. The Radio Frequency Identification (RFID) Technology can be used for vehicle identification to gather information in real-time from roads by getting the vehicles location from RFID readers placed in the vehicle. This paper focuses on designing the Public Vehicle Location System (PVLS). The proposed structure consists of passive RFID tags placed at various locations on the chosen route, RFID reader on the Bus, wireless communication with a PC and commanding software (RFID reader and database structure), also PVLS applications and website. The designed system controls, manages and monitors the performance of RFID readers. It also filters and stores the information in an appropriate format so that it could be used without difficulty in the application system and website. The system implemented by using RFID is placed in the Bus which is programmed by Visual C# 2008 with Compact .Net Framework.

关键词： RFID Vehicle Location Tracking Public Transport

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Comparative investigation of coal-and oil-fired boilers based on emission factors,ozone and secondary organic aerosol formation potentials of VOCs

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Journal of Environmental Sciences 2020年第6期32卷 245-255页

作者： Hsi-Hsien Yang sunil Kumar Gupta narayan Babu Dhital Lin-Chi Wang Suresh Pandian Elumalai Department of Environmental Engineering and Management Chaoyang University of TechnologyTaichungChinese Taipei Department of Applied Chemistry Chaoyang University of TechnologyTaichungChinese Taipei Department of Environmental Science Patan Multiple CampusTribhuvan UniversityLalitpurNepal Department of Environmental Engineering Chung Yuan Christian UniversityTaoyuanChinese Taipei Department of Environmental Science and Engineering Indian Institute of Technology(Indian School of Mines)DhanbadIndia

Volatile organic compounds(VOCs)are the important precursors of the tropospheric ozone(O3)and secondary organic aerosols(SOA),both of which are known to harm human health and disrupt the earth’s climate *** this study,VOC emission factors,O3 and SOA formation potentials were estimated for two types of industrial boilers:coal-fired boilers(n=3)and oil-fired boilers(n=3).Results showed that EVOCs concentrations were more than nine times higher for oil-fire d boilers compared to those for coal-fired *** factors ofΣVOCs were found to be higher for oil-fired boilers(9.26-32.83 mg-VOC/kg)than for coal-fired boilers(1.57-4.13 mg-VOC/kg).Alkanes and aromatics were obtained as the most abundant groups in coal-fired boilers,while oxygenated organics and aromatics were the most contributing groups in oil-fired ***,n-hexane and o-ethyl toluene were the abundant VOC species in coal-fired boiler emissions,whereas toluene was the most abundant VOC species emitted from oil-fired boilers.O3 and SOA formation potentials were found 12 and 18 times,respectively,higher for oil-fired than for coal-fired *** OFP ranged from 3.99 to 11.39 mg-O3/kg for coal-fired *** oil-fired boilers,total OFP ranged from 36.16 to 131.93 mg-O3/***,total secondary organic aerosol potential(SOAP)ranged from 65.4 to 122.5 mg-SOA/kg and 779.9 to 2252.5 mg-SOA/kg for the coal-fired and oil-fired boilers,respectively.

关键词： Coal-and oil-fired boilers Volatile organic compounds Emission factor Ozone formation potential Secondary organic aerosol potential

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Estimation of the effectiveness of multi-criteria decision analysis and machine learning approaches for agricultural land capability in Gangarampur Subdivision, Eastern India

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Artificial Intelligence in Geosciences 2022年第1期3卷 179-191页

作者： sunil Saha Prolay Mondal Department of Geography Raiganj UniversityRaiganjWest Bengal733134India

Land suitability analysis(LSA)is an evaluation method that measures the degree to which land is suitable for certain land *** primary aims of this study are to identify potentially viable agricultural land in the Gangarampur subdivision(West Bengal)using Multiple Criteria Decision Making(MCDM)and machine learning procedures and to evaluate the efficacy of the employed *** Analytic Hierarchy Process(AHP)model was used to assign relative weights to the fifteen various criteria in this suitability analysis,and then the Fuzzy Complex Proportional Assessment(FCOPRAS)model was applied using the AHP’s normalised pairwise comparison matrix,whereas the Waikato Environment for Knowledge Analysis(Weka)Software was used to apply machine learning algorithms to the field *** Random Forest(RF)model,on the other hand,is a better fit for the locational study of soil *** to the RF findings,areas of 14.67 per cent(15368.46 ha)are excellent(ZONE Ⅴ)for growing crops,approximately 22.30 per cent(23367.9 ha)are highly suitable(ZONE Ⅳ),and 23.63 per cent(24762.12 ha)are moderately suitable(ZONE Ⅲ)for cultivation,*** numbers for FCOPRAS are roughly 15.39%(16130.52 ha),22.54%(23620.65 ha),and 19.79%(20733.26 ha).The Receiver Operating Characteristic(ROC)curve and accuracy measurements of the results indicate the high accuracy of the applied models,with Random Forest and FCOPRAS being the most popular and effective *** study will make an important contribution to evaluations of soil fertility and site *** will help local government officials,academics,and farmers scientifically use the land.

关键词： Analytic Hierarchy Process Fuzzy Complex Proportional Assessment Receiver Operating Characteristic Gangarampur subdivision Soil Capability

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