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Mucinous neoplasm of the appendix:A case report and review of literature

World Journal of Gastrointestinal Surgery 2024年第3期16卷 944-954页

作者： Hao-Cheng Chang jung-Cheng Kang Ta-Wei Pu Ruei-Yu Su Chao-Yang Chen Je-Ming Hu Department of Surgery Tri-Service General HospitalTaipei 114TaiwanChina Division of Colon and Rectal Surgery Department of SurgeryTaiwanChina Adventist HospitalTaipei 105TaiwanChina Division of Colon and Rectal Surgery Department of SurgeryTri-Service General Hospital Songshan BranchNational Defense Medical CenterTaipei 105TaiwanChina Division of Colon and Rectal Surgery Department of SurgeryTri-Service General HospitalNational Defense Medical CenterTaipei 114TaiwanChina Department of Pathology Tri-Service General HospitalNational Defense Medical CenterTaipei 105TaiwanChina Department of Pathology and Laboratory Medicine Taoyuan Armed Forces General HospitalTaoyuan 325TaiwanChina

BACKGROUND Appendiceal mucinous neoplasms(AMNs),although not classified as rare,are relatively uncommon tumors most often discovered incidentally during colorectal *** identification of AMNs is difficult due to non-specific sym-ptoms,overlapping tumor markers with other conditions,and the potential for *** underscores the urgent need for precision in diagnosis to pre-vent severe *** SUMMARY This case report describes the unexpected discovery and treatment of a low-grade AMN(LAMN)in a 74-year-old man undergoing laparoscopic hemicolectomy for transverse colon adenocarcinoma(AC).Preoperatively,non-specific gastroin-testinal symptoms and elevated tumor markers masked the presence of *** tumor,presumed to be an AMN peritoneal cyst intraoperatively,was con-firmed as LAMN through histopathological *** neoplasm exhibited mucin accumulation and a distinct immunohistochemical profile:Positive for Ho-meobox protein CDX-2,Cytokeratin 20,special AT-rich sequence-binding protein 2,and Mucin 2 but negative for cytokeratin 7 and Paired box gene *** profile aids in distinguishing appendiceal and ovarian mucinous *** recovery was uncomplicated,and the patient initiated adjuvant chemotherapy for the colon *** This case highlights the diagnostic complexity of AMNs,emphasizing the need for vigilant identification to avert potential complications,such as pseudomyxoma peritonei.

关键词： Adenocarcinoma Appendiceal neoplasms Low-grade appendiceal mucinous neoplasm Peritoneal neoplasms Pseudomyxoma peritonei Case report

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RFID Positioning and Physiological Signals for Remote Medical Care

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Computer Systems Science & Engineering 2022年第4期41卷 289-304页

作者： Wen-Tsai sung sung-jung hsia. Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030Taiwan Department of Information Technology Takming University of Science and TechnologyTaipei City11451Taiwan

The safety of patients and the quality of medical care provided to them are vital for their *** study establishes a set of RFID(Radio Fre-quency Identiﬁcation)-based systems of patient care based on physiological sig-nals in the pursuit of a remote medical care *** RFID-based positioning system allows medical staff to continuously observe the patient's health and *** staff can thus respond to medical emergencies in time and appropriately care for the *** the COVID-19 pandemic broke out,the proposed system was used to provide timely information on the location and body temperature of patients who had been screened for the *** results of experiments and comparative analyses show that the proposed system is superior to competing systems in *** use of remote monitoring technology makes user interface easier to provide high-quality medical services to remote areas with sparse populations,and enables better care of the elderly and patients with mobility *** can be found from the experiments of this research that the accuracy of the position sensor and the ability of package delivery are the best among the other related *** presentation of the graphical interface is also the most cordial among human-computer interaction and the operation is simple and clear.

关键词： Remote medical care active RFID positioning physiological signal

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Improving Speech Enhancement Framework via Deep Learning

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Computers, Materials & Continua 2023年第5期75卷 3817-3832页

作者： sung-jung hsia. Wen-Tsai sung Department of Information Technology Takming University of Science and TechnologyTaipei City11451Taiwan Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030Taiwan

Speech plays an extremely important role in social *** individuals suffer from a“speech barrier,”which limits their communication with *** this study,an improved speech recognitionmethod is proposed that addresses the needs of speech-impaired and deaf individuals.A basic improved connectionist temporal classification convolutional neural network(CTC-CNN)architecture acoustic model was constructed by combining a speech database with a deep neural *** sensors were used to convert the collected voice signals into text or corresponding voice signals to improve *** method can be extended to modern artificial intelligence techniques,with multiple applications such as meeting minutes,medical reports,and verbatim records for cars,sales,*** experiments,a modified CTC-CNN was used to train an acoustic model,which showed better performance than the earlier common *** a CTC-CNN baseline acoustic model was constructed and optimized,which reduced the error rate to about 18%and improved the accuracy rate.

关键词： Artificial intelligence speech recognition speech to text CTC-CNN

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Home Monitoring of Pets Based on AIoT

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Computer Systems Science & Engineering 2022年第10期43卷 59-75页

作者： Wen-Tsai sung sung-jung hsia. Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung City411030Taiwan Department of Information Technology Takming University of Science and TechnologyTaipei City11451Taiwan

With technological and social development in recent decades,people have begun pursuing more comfortable lives that frequently feature household pets that are treated like members of the *** average,one out of every three households has a *** has also led to the creation and growth of many businesses in the pet industry.A few companies have developed a system that allows busy office workers to remotely care for pets at home based on the Internet of Things and an intelligent adjustment *** owners of two dogs,the authors of this study observed their pets’living habits and recorded environmental conditions that appear suitable for *** data were then used to develop an automatic control system to care for *** observational data on the pets’habits and environment were written in a program in Arduino by using the ESP8266 Wi-Fi *** module and booster module control is the switch and setting of various household *** to the loop setting of the program,the system does not need to manually switch or adjust the electrical settings of the ***,the pet's living environment is assessed by using various *** use of Arduino programs helps develop a system that can automatically adjust the environment to one that is most suitable for the pet's comfort.

关键词： Remote medical care active RFID positioning physiological signal

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Utilizing the Improved QPSO Algorithm to Build a WSN Monitoring System

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Computers, Materials & Continua 2022年第2期70卷 3529-3548页

This research uses the improved Quantum Particle Swarm Optimization(QPSO)algorithm to build an Internet of Things(IoT)life comfort monitoring system based on wireless sensing *** purpose is to improve the quality of intelligent *** functions of the system include automatic basketball court lighting system,monitoring of infants’sleeping posture and accidental falls of the elderly,human thermal comfort measurement and other related life comfort services,*** the hardware system of the IoT,this research is based on the latest version of ZigBee 3.0,which uses optical sensors,3-axis accelerometers,and temperature/humidity sensors in the IoT perception *** the network transmission layer,the central network architecture is used for *** the application layer,we have designed a graphical interface for real-time values and information that can be read at any time and place using mobile *** this study,authors use the improved QPSO algorithm in the calculation part,so that the target can be effectively positioned outside the numerous surveillance *** study uses various sensor data fusion technologies to make the IoT system becomes able to provide more extensive and even better services than ever *** short,this research work has proven to be an effective way to reduce power consumption,improve medical quality and provide higher comfort for intelligent lift level.

关键词： Quantum particle swarm optimization IoT wireless sensor network ZigBee

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Meningioma originating from the superior petrosal vein without dural attachment:A case report

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World Journal of Clinical Cases 2024年第17期12卷 3156-3160页

作者： Yeong-Jin Kim Shin jung Tae-Young jung Kyung-Sub Moon In-Young Kim Department of Neurosurgery Chonnam National University Medical SchoolChonnam National University Hwasun HospitalHwasun 58128South Korea

BACKGROUND Meningioma in the cerebellopontine angle(CPA)without dural attachment is extremely *** report a unique case of meningioma derived from the superior petrosal vein without dural *** SUMMARY A 44-year-old right-handed woman presented with a two-month history of headache and *** magnetic resonance imaging showed a well-defined contrast-enhancing lesion in the right CPA without a dural tail *** resection was performed using a right retro sigmoid approach.A dural attachment was not seen at the tentorium or posterior surface of the petrous *** tumor was firmly adherent to the superior petrosal *** origin site was cauterized and resected with the preservation of the superior petrosal vein.A diagnosis of meningothelial meningioma was *** patient’s headache and tinnitus gradually disappeared,and a recurrence was not observed five years after the *** The rare occurrence of meningioma without dural attachment makes it difficult to determine dural attachment before *** absence of dural attachment makes it easy to completely resect such *** related to tumors should be removed carefully,considering the possible presence of tumor stem cells in the microvessels.

关键词： Meningioma Dura mater Superior petrosal vein Tumor stem cell Case report

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Surface-modified Ag@Ru-P25 for photocatalytic CO_(2) conversion with high selectivity over CH_(4) formation at the solid–gas interface

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Carbon Energy 2024年第1期6卷 182-196页

作者： Chaitanya B.Hiragond Sohag Biswas Niket SPowar Junho Lee Eunhee Gong Hwapyong Kim Hong Soo Kim Jin-Woo jung Chang-Hee Cho Bryan M.Wong Su-Il In Department of Energy Science&Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Department of Chemical&Environmental Engineering Materials Science&Engineering ProgramDepartment of ChemistryDepartment of Physics&AstronomyUniversity of California-RiversideRiversideCaliforniaUSA Department of Physics and Chemistry Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea NiceScience Corporation DaeguRepublic of Korea

Systematic optimization of the photocatalyst and investigation of the role of each component is important to maximizing catalytic activity and comprehending the photocatalytic conversion of CO_(2) reduction to solar fuels.A surface-modified Ag@Ru-P25 photocatalyst with H_(2)O_(2) treatment was designed in this study to convert CO_(2) and H_(2)O vapor into highly selective *** doping followed by Ag nanoparticles(NPs)cocatalyst deposition on P25(TiO_(2))enhances visible light absorption and charge separation,whereas H_(2)O_(2) treatment modifies the surface of the photocatalyst with hydroxyl(–OH)groups and promotes CO_(2) ***-resonance transmission electron microscopy,X-ray photoelectron spectroscopy,X-ray absorption near-edge structure,and extended X-ray absorption fine structure techniques were used to analyze the surface and chemical composition of the photocatalyst,while thermogravimetric analysis,CO_(2) adsorption isotherm,and temperature programmed desorption study were performed to examine the significance of H_(2)O_(2) treatment in increasing CO_(2) reduction *** optimized Ag1.0@Ru1.0-P25 photocatalyst performed excellent CO_(2) reduction activity into CO,CH4,and C2H6 with a~95%selectivity of CH4,where the activity was~135 times higher than that of pristine TiO_(2)(P25).For the first time,this work explored the effect of H_(2)O_(2) treatment on the photocatalyst that dramatically increases CO_(2) reduction activity.

关键词： gas-phase CO_(2) reduction H_(2)O_(2) treatment plasmonic nanoparticles solar fuel photocatalyst surface modification

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Glucose-mediated mitochondrial reprogramming by cholesterol export at TM4SF5-enriched mitochondria-lysosome contact sites

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Cancer Communications 2024年第1期44卷 47-75页

作者： Ji Eon Kim So-Young Park Chulhwan Kwak Yoonji Lee Dae-Geun Song Jae Woo jung Haesong Lee Eun-Ae Shin Yangie Pinanga Kyung-hee Pyo Eun Hae Lee Wonsik Kim Soyeon Kim Chang-Duck Jun Jeanho Yun Sun Choi Hyun-Woo Rhee Kwang-Hyeon Liu jung Weon Lee Department of Pharmacy College of PharmacySeoul National UniversitySeoulRepublic of Korea Research Institute of Pharmaceutical Sciences College of PharmacySeoul National UniversitySeoulRepublic of Korea BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit College of Pharmacy and Research Institute of Pharmaceutical SciencesKyungpook National UniversityDaeguRepublic of Korea Department of Chemistry Seoul National UniversitySeoulRepublic of Korea College of Pharmacy Chung-Ang UniversitySeoulRepublic of Korea Natural Product Informatics Research Center Korea Institute of Science and Technology(KIST)Gangneung-siGangwon-doRepublic of Korea School of Life Sciences Gwangju Institute of Science and Technology(GIST)GwangjuRepublic of Korea Department of Biochemistry College of MedicineDong-A UniversityBusanRepublic of Korea Global AI Drug Discovery Center College of Pharmacy and Graduate School of Pharmaceutical SciencesEwha Womans UniversitySeoulRepublic of Korea Interdisciplinary Program in Genetic Engineering Seoul National UniversitySeoulRepublic of Korea

Background:Transmembrane 4 L six family member 5(TM4SF5)translocates subcellularly and functions metabolically,although it is unclear how intracellu-lar TM4SF5 translocation is linked to metabolic *** is thus of interests to understand how the traffic dynamics of TM4SF5 to subcellular endosomal membranes are correlated to regulatory roles of ***:Here,we explored the metabolic significance of TM4SF5 localization at mitochondria-lysosome contact sites(MLCSs),using in vitro cells and in vivo animal systems,via approaches by immunofluorescence,proximity labelling based proteomics analysis,organelle reconstitution ***:Upon extracellular glucose repletion following depletion,TM4SF5 became enriched at MLCSs via an interaction between mitochondrial FK506-binding protein 8(FKBP8)and lysosomal *** labeling showed molecular clustering of phospho-dynamic-related protein I(DRP1)and certain mitophagy receptors at TM4SF5-enriched MLCSs,leading to mitochondrial fis-sion and ***4SF5 bound NPC intracellular cholesterol transporter 1(NPC1)and free cholesterol,and mediated export of lysosomal cholesterol to mitochondria,leading to impaired oxidative phosphorylation but intact tri-carboxylic acid(TCA)cycle andβ-*** mouse models,hepatocyte Tm4sf5 promoted mitophagy and cholesterol transport to mitochondria,both with positive relations to liver ***:Our findings suggested that TM4SF5-enriched MLCSs regu-late glucose catabolism by facilitating cholesterol export for mitochondrial reprogramming,presumably while hepatocellular carcinogenesis,recapitulating aspects for hepatocellular carcinoma metabolism with mitochondrial repro-gramming to support biomolecule synthesis in addition to glycolytic energetics.

关键词： cholesterol fluorescent imaging glucose catabolism hepatocellular carcinogenesis mem-brane contact sites mitochondria function mitophagy oxidative phosphorylation protein-protein interaction tetraspanin

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Artificial optoelectronic synapse based on spatiotemporal irradiation to source-sharing circuitry of synaptic phototransistors

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InfoMat 2024年第2期6卷 131-141页

作者： Seungho Song Changsoon Choi Jongtae Ahn Je-Jun Lee Jisu Jang Byoung-Soo Yu jung Pyo Hong Yong-Sang Ryu Yong-Hoon Kim Do Kyung Hwang Center for Opto-Electronic Materials and Devices Post-Silicon Semiconductor InstituteKorea Institute of Science and Technology(KIST)SeoulRepublic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Center for Spintronics Post-Silicon Semiconductor InstituteKorea Institute of Science and Technology(KIST)SeoulRepublic of Korea Division of Nanoscience&Technology KIST SchoolUniversity of Science and Technology(UST)SeoulRepublic of Korea School of Biomedical Engineering Korea UniversitySeoulRepublic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoulRepublic of Korea

To overcome the intrinsic inefficiency of the von Neumann architecture,neuromorphic devices that perform analog vector–matrix multiplication have been highlighted for achieving power-and time-efficient data *** particular,artificial synapses,of which conductance should be programmed to represent the synaptic weights of the artificial neural network,have been intensively researched to realize neuromorphic ***,inspired by excitatory and inhibitory synapses,we develop an artificial optoelectronic synapse that shows both potentiation and depression characteristics triggered only by optical *** design of the artificial optoelectronic synapse,in which excitatory and inhibitory synaptic phototransistors are serially connected,enables these characteristics by spatiotemporally irradiating the phototransistor channels with optical ***,a negative synaptic weight can be realized without the need for electronic components such as *** such attributes,the artificial optoelectronic synapse is demonstrated to classify three digits with a high recognition rate(98.3%)and perform image preprocessing via analog vector-matrix multiplication.

关键词： amorphous oxide semiconductor analog processing artificial synapse neuromorphic optoelectronics

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Speech Recognition via CTC-CNN Model

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Computers, Materials & Continua 2023年第9期76卷 3833-3858页

作者： Wen-Tsai sung Hao-WeiKang sung-jung hsia. Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030Taiwan Department of Information Technology Takming University of Science and TechnologyTaipei11451Taiwan

In the speech recognition system,the acoustic model is an important underlying model,and its accuracy directly affects the performance of the entire *** paper introduces the construction and training process of the acoustic model in detail and studies the Connectionist temporal classification(CTC)algorithm,which plays an important role in the end-to-end framework,established a convolutional neural network(CNN)combined with an acoustic model of Connectionist temporal classification to improve the accuracy of speech *** study uses a sound sensor,ReSpeakerMic Array v2.0.1,to convert the collected speech signals into text or corresponding speech signals to improve communication and reduce noise and hardware *** baseline acousticmodel in this study faces challenges such as long training time,high error rate,and a certain degree of *** model is trained through continuous design and improvement of the relevant parameters of the acousticmodel,and finally the performance is selected according to the evaluation ***,which reduces the error rate to about 18%,thus improving the accuracy ***,comparative verificationwas carried out from the selection of acoustic feature parameters,the selection of modeling units,and the speaker’s speech rate,which further verified the excellent performance of the CTCCNN_5+BN+Residual model *** terms of experiments,to train and verify the CTC-CNN baseline acoustic model,this study uses THCHS-30 and ST-CMDS speech data sets as training data sets,and after 54 epochs of training,the word error rate of the acoustic model training set is 31%,the word error rate of the test set is stable at about 43%.This experiment also considers the surrounding environmental *** the noise level of 80∼90 dB,the accuracy rate is 88.18%,which is the worst performance among all *** contrast,at 40–60 dB,the accuracy was as high as 97.33%due to less noise pollution.

关键词： Artificial intelligence speech recognition speech to text convolutional neural network automatic speech recognition

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