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Management of the enteroatmospheric fistula:A case report

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World Journal of Clinical Cases 2022年第20期10卷 6954-6959页

作者： Jinbeom Cho Kiyoung sung Dosang lee Department of Surgery College of MedicineThe Catholic University of KoreaSeoul 06591South Korea

BACKGROUND Enteroatmospheric fistula(EAF)is a catastrophic complication that can occur after open *** cause severe body fluid loss,hypercatabolism,and wound complications,leading to adverse clinical *** SUMMARY A 72-year-old female patient underwent ventral hernia *** days after the surgery,she exhibited severe abdominal pain with septic *** laparotomy revealed extensive intestinal adhesions and severe intraperitoneal *** the patient was hemodynamically unstable,a salvage operation rather than definite surgery was needed,and three surgical open drains were inserted into the peritoneal *** EAFs developed,and it was almost impossible to isolate and reduce the fistula output despite the use of vacuum-assisted closure dressings and endoscopic stent ***,we anastomosed two vascular grafts to the openings of each EAF to restore enteric *** inserted vascular grafts showed acceptable patency,and the patient could receive optimal nutritional support with elemental enteral *** underwent EAF resection 76 d after graft *** Control of the enteric effluent are key elements in achieving favorable clinical conditions which should precede definite surgery for EAFs.

关键词： Enterocutaneous fistula Enteroatmospheric fistula Ventral hernia Complication Sepsis Case report

Aluminum nitride waveguide beam splitters for integrated quantum photonic circuits

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光子学研究:英文版 2023年第7期11卷 1196-1202页

作者： HYEONG-SOON JANG DONGHWA lee HYUNGJUN HEO YONG-SU KIM HYANG-TAG LIM SEUNG-WOO JEON sung MOON SANGIN KIM SANG-wook HAN HOJOONG JUNG Center for Quantum Information Korea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Department of Electrical and Computer Engineering Ajou UniversitySuwon 16499Republic of Korea Division of Nano and Information Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea

We demonstrate integrated photonic circuits for quantum devices using sputtered polycrystalline aluminum nitride(Al N)on ***-chip Al N waveguide directional couplers,which are one of the most important components in quantum photonics,are fabricated and show the output power splitting ratios from 50:50 to 99:*** beam splitters with an extinction ratio of more than 10 d B are also realized from the Al N directional *** the fabricated Al N waveguide beam splitters,we observe Hong–Ou–Mandel interference with a visibility of 91.7%±5.66%.

关键词： waveguide quantum beam

Self-motivated,thermally oxidized hematite nanoflake photoanodes:Effects of pre-polishing and ZrO_(2) passivation layer

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Journal of Energy Chemistry 2022年第2期31卷 415-423页

作者： Love Kumar Dhandole Hyun Hwi lee Weon-Sik Chae Jum Suk Jang Jae sung lee Department of Energy Engineering School of Energy and Chemical EngineeringUlsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea Division of Biotechnology College of Environmental and Bioresource SciencesChonbuk National UniversityIksan 54596Republic of Korea Pohang Accelerator Laboratory Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Daegu Center Korea Basic Science InstituteDaegu 41566Republic of Korea

High-temperature thermal oxidation of an Fe foil produces a high-quality,crystalline hematite nanoflake suitable as a photoanode for the photoelectrochemical(PEC)water *** pre-polishing of the foil surface has a profound effect in the formation of a vertically-aligned nanoflakes of hematite phase with extended(110)planes by removing the loosely-bonded oxide *** the surface of the photoanode is modified with a ZrO_(2) passivation layer and a cobalt phosphate co-catalyst,the charge recombination at the photoanode-electrolyte interface is greatly suppressed to improve its overall PEC *** a result,the photocurrent density at 1.10 VRHE under 1 sun condition is enhanced from 0.22 mA cm^(-2) for an unmodified photoanode to 0.59 mA cm^(-2) for the fully modified photoanode,and the photocurrent onset potential is shifted cathodically by 400 ***,the photoanode demonstrates outstanding stability by showing steady production of H_(2) and O_(2) gases in the stoichiometric ratio of 2:1 in a continuous PEC operation for 10 h.

关键词： Fe foil Thermal oxidation Nanoflakes Photoelectrochemical water splitting Surface modifications

Graphene Bridge Heterostructure Devices for Negative Differential Transconductance Circuit Applications

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Nano-Micro Letters 2023年第2期15卷 161-171页

作者： Minjong lee Tae wook Kim Chang Yong Park Kimoon lee Takashi Taniguchi Kenji Watanabe Min‑gu Kim Do Kyung Hwang Young Tack lee Department of Electrical and Computer Engineering Inha UniversityIncheon 22212Republic of Korea Department of Materials Science and Engineering The University of Texas at DallasRichardsonTX 75080USA Center for Opto‑Electronic Materials and Devices Post‑Silicon Semiconductor InstituteKorea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Department of Physics Kunsan National UniversityGunsan 54150Republic of Korea Advanced Materials Laboratory National Institute for Materials ScienceTsukuba 305‑0044Japan Department of Information and Communication Engineering Inha UniversityIncheon 22212Republic of Korea Division of Nanoscience and Technology KIST SchoolUniversity of Science and Technology(UST)Seoul 02792Republic of Korea Department of Electronic Engineering Inha UniversityIncheon 22212Republic of Korea

Two-dimensional van der Waals(2D vdW)material-based heterostructure devices have been widely studied for high-end electronic applications owing to their heterojunction *** this study,we demonstrate graphene(Gr)-bridge heterostructure devices consisting of laterally series-connected ambipolar semiconductor/Gr-bridge/n-type molybdenum disulfide as a channel material for field-effect transistors(FET).Unlike conventional FET operation,our Gr-bridge devices exhibit nonclassical transfer characteristics(humped transfer curve),thus possessing a negative differential *** phenomena are interpreted as the operating behavior in two series-connected FETs,and they result from the gate-tunable contact capacity of the Gr-bridge ***-value logic inverters and frequency tripler circuits are successfully demonstrated using ambipolar semiconductors with narrow-and wide-bandgap materials as more advanced circuit applications based on non-classical transfer ***,we believe that our innovative and straightforward device structure engineering will be a promising technique for future multi-functional circuit applications of 2D nanoelectronics.

关键词： Graphene bridge Heterostructure device Non-classical transfer characteristics Multi-value logic inverter Frequency tripler

Estimation of marine winds in and around typhoons using multi-platform satellite observations: Application to Typhoon Soulik (2018)

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Frontiers of Earth Science 2022年第1期16卷 175-189页

作者： Seung-Woo lee sung Hyun NAM Duk-Jin KIM School of Earth and Environmental Sciences College of Natural SciencesSeoul National UniversitySeoul 08826Republic of Korea Research Institution of Oceanography College of Natural SciencesSeoul National UniversitySeoul 08826Republic of Korea

Estimating horizontal winds in and around typhoons is important for improved monitoring and prediction of typhoons and mitigating their ***,we present a new algorithm for estimating typhoon winds using multiple satellite observations and its application to Typhoon Soulik(2018).Four kinds of satellite remote sensing data,along with their relationship to typhoon intensity,derived statistically from hundreds of historical typhoon cases,were merged into the final product of typhoon wind(MT wind):(1)geostationarysatellite-based infrared images(IR wind),(2)passive microwave sounder(MW wind),(3)feature-tracked atmospheric motion vectors,and (4)scatterometer-based sea surface winds(SSWs).The algorithm was applied to two cases(A and B)of Typhoon Soulik and validated against SSWs independently retrieved from active microwave synthetic aperture radar(SAR)and microwave radiometer(AMSR2)images,and vertical profiles of wind speed derived from reanalyzed data and dropsonde *** Case A(open ocean),the algorithm estimated the realistic maximum wind,radius of maximum wind,and radius of 15 m/s,which could not be estimated using the reanalysis data,demonstrating reasonable and practical ***,for Case B(when the typhoon rapidly weakened just before making landfall in the Korean Peninsula),the algorithm significantly overestimated the parameters,primarily due to the overestimation of typhoon *** study highlights that realistic typhoon winds can be monitored continuously in real-time using multiple satellite observations,particularly when typhoon intensity is reasonably well predicted,providing timely analysis results and products of operational importance.

关键词： sea surface wind multi-platform satellites Typhoon Soulik(2018)

Flexible and disposable paper-based gas sensor using reduced graphene oxide/chitosan composite

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Journal of Materials Science & Technology 2022年第6期101卷 165-172页

作者： Hyunjun Park Woong Kim Sang Won lee Joohyung Park Gyudo lee Dae sung Yoon Wonseok lee Jinsung Park Department of Control and Instrumentation Engineering Korea UniversitySejong 30019Republic of Korea School of Biomedical Engineering Korea UniversitySeoul 02841Republic of Korea Department of Biotechnology and Bioinformatics Korea UniversitySejong 30019Republic of Korea Department of Electrical Engineering Korea National University of TransportationChungju 27469Republic of Korea

Nitrogen dioxide(NO_(2))is a representative toxicant in air pollution that mostly arises from the exhaust gas released by *** is related to various respiratory diseases such as pneumonia and sudden infant death ***,because the toxicity of nitrogen dioxide is high in overpopulated areas(i.e.,a capital or metropolis),the development of simple,practical,and facile sensors is highly *** work presents a flexible and disposable paper-based NO_(2)sensor based on a reduced graphene oxide/chitosan(r GO/CS)*** synthesized r GO/CS composite can be easily flexed and deformed into various shapes,which are attributed to chitosan molecules that function as a dispersion and reduction agent and support *** addition,this composite can be attached to paper owing to its adhesive property;hence it can be utilized in versatile applications in a disposable *** analyzing the conductive change of the r GO/CS composite when it reacts with NO_(2),we can detect nitrogen dioxide in a concentration range of 0–100 ppm with a detection limit of 1 ***,we performed NO_(2)detection in the exhaust gas released by automobiles using the r GO/CS composite for practical *** results indicated that the r GO/CS composite has the potential to be used in feasible gas sensing as a facile and disposable sensor under various conditions.

关键词： Reduced graphene oxide Chitosan Composite material Nitrogen dioxide Paper-based gas sensor Flexible and disposable sensor

A novel electrospinning method for self-assembled tree-like fibrous scaffolds:Microenvironment-associated regulation of MSC behavior and bone regeneration

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Journal of Materials Science & Technology 2022年第20期115卷 52-70页

作者： Jeong In Kim Ju Yeon Kim sung-Ho Kook Jeong-Chae lee Cluster for Craniofacial Development and Regeneration Research Institute of Oral Biosciences and School of DentistryJeonbuk National UniversityJeonju 54896Republic of Korea Department of Bionanosystem Engineering Jeonbuk National UniversityJeonju 54896Republic of Korea Department of Bioactive Material Sciences Research Center of Bioactive MaterialsJeonbuk National UniversityJeonju 54896Republic of Korea

Numerous studies highlight advantages of electrospun scaffolds in bone tissue engineering,in which cellular behavior is tightly affected by fiber topographical cues of ***,the classic electrospinning setup limits a desired presentation of biomimetic fibrous microenvironments that sense mechanosignaling and regulate stem cell *** aims of this study were to fabricate advanced asspun scaffolds presenting tree-like microfiber/nanonet networks and to evaluate their regulatory potentials on behavior of human mesenchymal stem cells(h MSCs)and bone *** we developed a novel electrospinning setup that allowed the presentation of patterned Trunk microfibers(TMF)and/or branched nanonet fibers(BNn Fs)in biomimetic fibrous *** the cellular mechanisms,anisotropichierarchical topography of TMF controlled behavior of h MSCs through focal adhesion formation and Yesassociated protein(YAP)induction,whereas BNn F disturbed such mechanosensing responses in the *** fiber microenvironment-related expression and nuclear localization of YAP *** correlated with the potentials of as-spun scaffolds to enhance osteogenic differentiation of the h MSCs and alveolar bone defect healing in an animal ***,this study provides an advanced approach of the modified electrospinning setup for presentation of biomimetic fibrillar microenvironments in as-spun scaffolds along with their application in stem cell behavior regulation and regenerative tissue engineering.

关键词： Electrospinning Advanced biomimetic scaffolds Stem cell behavior Mechanosensing Bone tissue engineering

Nitrile Electrolyte Strategy for 4.9 V-Class Lithium-Metal Batteries Operating in Flame

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Energy & Environmental Materials 2023年第3期6卷 229-237页

作者： Hyunseok Moon sung-Ju Cho Dae-Eun Yu Sang-Young lee Department of Chemical and Biomolecular Engineering Yonsei UniversitySeoul 03722Korea Molecular Foundry Lawrence Berkeley National LaboratoryBerkeley CA USA Batteries R&D Center LG Energy SolutionDaejeon 34122Korea

Challenges facing high-voltage/high-capacity cathodes,in addition to the longstanding problems pertinent to lithium(Li)-metal anodes,should be addressed to develop high-energy-density Li-metal *** issue mostly stems from interfacial instability between electrodes and *** carbonate-or ether-based liquid electrolytes suffer from not only volatility and flammability but also limited electrochemical stability ***,we report a nitrile electrolyte strategy based on concentrated nitrile electrolytes(CNEs)with *** CNE consists of high-concentration lithium bis(fluorosulfonyl)imide(LiFSI)in a solvent mixture of succinonitrile(SN)/acetonitrile(AN).The SN/AN solvent mixture is designed to ensure high oxidation stability along with thermal stability,which are prerequisites for high-voltage Li-metal *** CNE exhibits interfacial stability with Li metals due to the coordinated solvation *** nitrate(LiNO_(3))and indium fluoride(InF_(3))are incorporated in the CNE as synergistic co-additives to further stabilize solid-electrolyte interphase(SEI)on Li *** resulting electrolyte(CNE+LiNO_(3)/InF_(3))enables stable cycling performance in Li||LiNi_(0.8)Co_(0.1)Mn_(0.1)and 4.9 V-class Li||LiNi_(0.5)Mn_(1.5)O_(4)***,the Li||LiNi_(0.5)Mn_(1.5)O_(4)cell maintains its electrochemical activity at high temperature(100℃)and even in flame without fire or explosion.

关键词： 4.9 V-class cathodes electrolyte-electrode interfaces lithium-metal batteries nitrile electrolytes safety

Curcumin-induced cell death depends on the level of autophagic flux in A172 and U87MG human glioblastoma cells

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Chinese Journal of Natural Medicines 2020年第2期18卷 114-122页

作者： lee Jong-Eun Yoon sung Sik lee Jae-wook Moon Eun-Yi Department of Bioscience and Biotechnology Sejong UniversitySeoul 05006Republic of Korea

Glioblastoma is the deadliest neoplasm with the worst 5-year survival rate among all human *** promotes autophagic cell death or blocks the induction of apoptosis in eukaryotic ***,we investigated whether varying levels of autophagic flux in glioblastoma lead to different efficacies of curcumin treatment using U87 MG and A172 human glioblastoma *** number of LC3 puncta,the number of cells with LC3 puncta and the level of LC3 Ⅱ,Atg5 and Atg7 protein were higher in U87 MG cells compared with A172 *** the cells were incubated with curcumin for 24 or 48 h,the percentage of cell death was higher in A172 cells compared with U87 MG *** the level of LC3 was lower,that of curcumin-induced LC3 was higher,in A172 cells than in U87 MG *** relative increases in cell death and LC3-mediated autophagy were greater under serum starvation in A172 cells compared with U87 MG ***-induced A172 cell death was reduced by serum *** both types of cells were transfected with LC3-GFP,the percentage of cell death was higher in A172 cells than that in U87 MG *** together,the data demonstrate that curcumin-mediated tumor cell death is regulated by the basal level of autophagic flux in different glioblastoma *** suggests that prior to the use of various curcumin therapeutics,the level of basal or induced autophagic flux should be carefully examined in tumor cells for the best efficacy.

关键词： Glioblastoma A172 U87MG Autophagic flux Curcumin