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Neural Regeneration Research 2017年第5期12卷 765-769页

作者： Sun Wook Park sung min son Na Kyung Lee Department of Physical Therapy Faculty of Health Science Eulji University Department of Physical Therapy College of Health Science Cheongju University Department of Physical Therapy College of Rehabilitation Science Daegu University

This study aimed to investigate the effects of exercise-induced muscle fatigue in the unaffected knee joint on postural control and kinematic changes in stroke patients. Forty participants（20 stroke patients, 20 age-matched healthy participants） were recruited. To induce fatigue, maximum voluntary isometric contractions were performed in the unaffected knee joint in a Leg Extension Rehab exercise machine using the pneumatic resistance. We measured static and dynamic balance and lower-limb kinematics during gait. Changes in postural control parameters anteroposterior sway speed and total center of pressure distance differed significantly between the stroke and control groups. In addition, changes in gait kinematic parameters knee and ankle angles of initial contact differed significantly between stroke（paretic and non-paretic） and control groups. Muscle fatigue in the unaffected knee and ankle impaired postural control and debilitates kinematic movement of ipsilateral and contralateral lower limbs, and may place the fatigued stroke patients at greater risk for falls.

关键词： nerve regeneration knee muscle fatigue stroke postural control gait kinemetics neural regeneration

Does hemispheric lateralization influence therapeutic effects of transcranial direct current stimulation?

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Neural Regeneration Research 2016年第1期11卷 126-129页

作者： Yong Hyun Kwon Kyung Woo Kang Na Kyung Lee sung min son Department of Physical Therapy Yeungnam University College Department of Physical Therapy College of Rehabilitation Science Daegu University Department of Physical Therapy College of Health Science Cheongju University

This study investigated the effect of transcranial direct current stimulation（t DCS） polarity depending on lateralized function of task property in normal individuals performing visuomotor and simple repetitive tasks. Thirty healthy participants with no neurological disorders were recruited to participate in this study. Participants were randomly allocated into active or control condition. For the active condition, t DCS intensity was 2 m A with stimulation applied for 15 minutes to the right hemisphere（t DCS condition）. For the sham control, electrodes were placed in the same position, but the stimulator was turned off after 30 seconds（sham condition）. The tapping and tracking task tests were performed before and after for both conditions. Univariate analysis revealed significant difference only in the tracking task. For direct comparison of both tasks within each group, the tracking task had significantly higher Z score than the tapping task in the t DCS group（P 〈 0.05）. Thus, our study indicates that stimulation of the right hemisphere using t DCS can effectively improve visuomotor（tracking） task over simple repetitive（tapping） task.

关键词： nerve regeneration transcranial direct current stimulation visuomotor task tracking task task property hemispheric lateralization neural regeneration

Is effect of transcranial direct current stimulation on visuomotor coordination dependent on task difficulty?

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Neural Regeneration Research 2015年第3期10卷 463-466页

作者： Yong Hyun Kwon Kyung Woo Kang sung min son Na Kyung Lee Department of Physical Therapy Yeungnam University College Department of Physical Therapy College of Rehabilitation ScienceDaegu University Department of Physical Therapy College of Health Science Cheongju University

Transcranial direct current stimulation （tDCS）, an emerging technique for non-invasive brain stimulation, is increasingly used to induce changes in cortical excitability and modulate motor behavior, especially for upper limbs. The purpose of this study was to investigate the effects of tDCS of the primary motor cortex on visuomotor coordination based on three levels of task difficulty in healthy subjects. Thirty-eight healthy participants underwent real tDCS or sham tDCS. Using a single-blind, sham-controlled crossover design, tDCS was applied to the primary motor cortex. For real tDCS conditions, tDCS intensity was 1 mA while stimulation was applied for 15 minutes. For the sham tDCS, electrodes were placed in the same position, but the stimu- lator was turned off after 5 seconds. Visuomotor tracking task, consisting of three levels （levels 1, 2, 3） of difficulty with higher level indicating greater difficulty, was performed before and after tDCS application. At level 2, real tDCS of the primary motor cortex improved the accurate index compared to the sham tDCS. However, at levels 1 and 3, the accurate index was not significantly increased after real tDCS compared to the sham tDCS. These findings suggest that tasks of mod- erate difficulty may improve visuomotor coordination in healthy subjects when tDCS is applied compared with easier or more difficult tasks.

关键词： neural regeneration transcranial direct current stimulation visuomotor coordination task difficulty primary motor area motor learning neural regeneration

Generation of double knockout cattle via CRISPR-Cas9 ribonucleoprotein(RNP)electroporation

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Journal of Animal Science and Biotechnology 2024年第1期15卷 456-462页

作者： Gyeong-min Gim Kyeong-Hyeon Eom Dong-Hyeok Kwon Dae-Jin Jung Dae-Hyun Kim Jun-Koo Yi Jae-Jung Ha Ji-Hyun Lee Seong-Beom Lee Woo-Jae son Soo-Young Yum Won-Wu Lee Goo Jang Laboratory of Theriogenology and Biotechnology Department of Veterinary Clinical ScienceCollege of Veterinary Medicine and the Research Institute of Veterinary ScienceSeoul National UniversitySeoulRepublic of Korea LARTBio Co. Ltd.SeoulRepublic of Korea Gyeongsangbukdo Livestock Research Institute YeongjuRepublic of Korea Comparative Medicine Disease Research Center Seoul National UniversitySeoulRepublic of Korea

Background Genome editing has been considered as powerful tool in agricultural ***,genome editing progress in cattle has not been fast as in other mammal species,for some disadvantages including long gestational periods,single pregnancy,and high raising ***,technically demanding methods such as microinjection and somatic cell nuclear transfer(SCNT)are needed for gene editing in *** this point of view,electroporation in embryos has been risen as an *** First,editing efficiency of our electroporation methods were tested for *** of mutation on embryo was confirmed by T7E1 *** first combination,mutation rates for MSTN and PRNP were 57.6%±13.7%and 54.6%±13.5%,*** case of MSTN/BLG,mutation rates were 83.9%±23.6%for MSTN,84.5%±18.0%for ***,the double-KO embryos were transferred to surrogates and mutation rate was identified in resultant calves by targeted deep *** recipients were transferred for MSTN/PRNP,4 calves were delivered,and one calf underwent an induction for double *** surrogates were given double-KO embryos for MSTN/BLG,and four of the six calves that were born had mutations in both *** These data demonstrated that production of genome edited cattle via electroporation of RNP could be effectively ***,MSTN and PRNP from beef cattle and MSTN and BLG from dairy cattle have been born and they will be valuable resources for future precision breeding.

关键词： Beta-lactoglobulin Cattle CRISPR-Cas9 Electroporation Knockout MSTN PRNP

Paenarthrobacter nitroguajacolicus can promote cucumber growth and control cucumber corynespora leaf spot

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Frontiers of Agricultural Science and Engineering 2024年第3期11卷 485-498页

作者： min LI Yahui HUANG Xiaomin DONG Xu ZHANG Qing MA College of Horticulture South China Agricultural UniversityGuangzhou 510642China State Key Laboratory of Crop Stress Biology for Arid Areas/College of Plant Protection Northwest A&F UniversityYangling 712100China College of Forestry and Landscape Architecture South China Agricultural UniversityGuangzhou 510642China

Currently,the disease control in cucumber mainly depends on agrochemicals,which is not an environmentally benign *** bacteria not only resist plant pathogens but also promote plant growth,which is ecofriendly and sustainable option.A biocontrol bacterial strain BJ-5 was screened using Corynespora cassiicola as the target pathogen,and BJ-5 was determined to be Paenarthrobacter nitroguajacolicus by morphological and molecular *** effect of BJ-5 on *** was studied,including the spore germination,cell membrane permeability and infected ***-5 inhibited the germination of *** spores in vitro and led to atrophy and deformation of the *** budding ***-5 caused the relative extracellular conductivity of *** mycelia to increase compared with the ***,BJ-5 reduced the severity of cucumber corynespora leaf spot of cucumber infected with *** inhibition efficacy of BJ-5 suspension as a foliar spray against cucumber corynespora leaf spot reached 63%inhibition,which is higher than a 5000-fold dilution of Luna-son SC *** addition,BJ-5 was tested on the emergence of cucumber seedlings,recording the biomass and photosynthesis of cucumber during the growth ***-5 at 1.5×10^(5)CFU·mL^(−1)promoted the germination of cucumber seeds and increased biomass and photosynthesis at the adult plant ***,the secondary metabolites of BJ-5 were ***-5 could produce chitinases,siderophore,cellulase,amylase and protease in the respective ***,adaptation assay of BJ-5 showed good salt tolerance and good adaptability in alkaline conditions,and that BJ-5 retains inhibition of fungi activity at higher *** is the first report of the biocontrol by *** with antagonism to *** and promote cucumber *** study indicates that *** may serve as potential biocontrol agents against cucumber corynespora leaf spot fungu

关键词： Adaptability antagonistic bacterium disease resistance growth promotion secondary metabolite

Boosting electrocatalytic activity with the formation of abundant heterointerfaces and N, S dual-doped carbon nanotube for rechargeable Zn-air battery

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Journal of Energy Chemistry 2023年第9期84卷 140-152页

作者： Rin Na Kyeongseok min Hyejin Kim Yujin son Sang Eun Shim sung-Hyeon Baeck Department of Chemistry and Chemical Engineering Education and Research Center for Smart Energy Materials and ProcessInha UniversityIncheon 22212Republic of Korea

Herein,a facile synthetic strategy is proposed to fabricate high-performance electrocatalysts for rechargeable Zn-air batteries(ZABs).Heterostructured NiCo/NiCo_(2)S_(4) nanoparticles encapsulated in N-,S-co-doped CNT(NiCo/NiCo_(2)S_(4)@NSCNT) are synthesized via co-precipitation,thermal carbonization,and partial sulfidation *** strongly coupled NiCo/NiCo_(2)S_(4) heterostructure can improve the redox property and charge transfer ***,the CNTs with abundant foreign dopants provide high electrical conductivity and abundant defect sites for both the oxygen evolution reaction(OER) and oxygen reduction reaction(ORR).The prepared NiCo/NiCo_(2)S_(4)@NSCNT electrocatalyst exhibits a low overpotential of 349 mV at a current density of 10 mA cm-2 and a half-wave potential of 0.865 V for the OER and ORR,***,the ZAB assembled using as-prepared NiCo/NiCo_(2)S_(4)@NSCNT can provide superior specific capacity(756.16 mA h g_(Zn)^(-1)],peak power density(155.82 mW cm^(-2)),and long-term cyclability compared to those of the precious metal-based electrocatalyst(Pt/C+RuO_(2)).

关键词： Bifunctional electrocatalyst NiCo alloy Bimetallic sulfide Heterojunction Zinc–air battery

Controllable substitutional vanadium doping in wafer-scale molybdenum disulfide films

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Nano Research 2023年第2期16卷 3415-3421页

作者： Jihyung Seo Eunbin son Jiha Kim Sun-Woo Kim Jeong min Baik Hyesung Park Department of Materials Science and Engineering Graduate School of Semiconductor Materials and Devices EngineeringGraduate School of Carbon NeutralityLow Dimensional Carbon Materials CenterUlsan National Institute of Science and TechnologyUlsan 44919Republic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea SKKU Institute of Energy Science and Technology Sungkyunkwan UniversitySuwon 16419Republic of Korea

Substitutional atomic doping of transition metal dichalcogenides(TMDs)in the chemical vapor deposition(CVD)process is a promising and effective strategy for modifying their physicochemical ***,the conventional CVD method only allows narrow-range modulation of the dopant concentration owing to the low reactivity of the ***,the growth of wafer-scale monolayer TMD films with high dopant concentrations is much more ***,we report a facile doping approach based on liquid precursor-mediated CVD process for achieving high vanadium(V)doping in the MoS_(2)lattice with excellent doping uniformity and *** lateral growth of the host MoS_(2)lattice and the reactivity of the V precursor were simultaneously improved by introducing an alkali metal halide as a reaction *** metal halide promoter enabled the wafer-scale synthesis of V-incorporated MoS_(2)monolayer film with excessively high doping *** excellent wafer-scale uniformity of the highly V-doped MoS_(2)film was confirmed through a series of microscopic,spectroscopic,and electrical analyses.

关键词： doping concentration reaction promoter substitutional doping transition metal dichalcogenides wafer-scale growth

Moving Target Landing of a Quadrotor Using Robust Optimal Guaranteed Cost Control

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IEEE/CAA Journal of Automatica Sinica 2023年第3期10卷 819-821页

作者： Kewei Xia Seong-min Lee Wonmo Chung Yao Zou Hungsun son Department of Mechanical Engineering Ulsan National Institute of Science and TechnologyUlsan 44919South Korea Institute of Artificial Intelligence University of Science and Technology BeijingBeijing 100083China IEEE

Dear Editor,This letter proposes a robust control strategy for the autonomous landing of a quadrotor on a moving ***,a force command that consists of a cascade dynamics estimator and an optimal guaranteed cost control law is exploited for the position-loop ***,an orientation constraint torque command is employed for the attitude-loop tracking such that the quadrotor refrains from flipping during the landing operation.

关键词： Optimal constraint autonomous

Engineering Geometric Electrodes for Electric Field-Enhanced High-Performance Flexible In-Plane Micro-Supercapacitors

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Energy & Environmental Materials 2023年第4期6卷 114-120页

作者： Jihong Kim sung min Wi Jong-Guk Ahn Sangjun son Hee Young Lim Yeonsu Park Hye Ji Eun Jong Bae Park Hyunseob Lim Sangyeon Pak A-Rang Jang Young-Woo Lee Department of Energy Engineering Soonchunhyang UniversityAsan 31538Korea Department of Chemistry Gwangju Institute of Science and TechnologyGwangju 61005Korea Jeonju Centre Korea Basic Science InstituteJeonju 54907Korea Prof.S.Pak School of Electronic and Electrical Engineering Hongik UniversitySeoul 04066Korea Division of Electrical Electronic and Control EngineeringKongju National UniversityCheonan 31080Korea

In plane micro-supercapacitors that are miniaturized energy storage components have attracted significant attention due to their high power densities for various ubiquitous and sustainable device systems as well as their facile integration on various flexible/wearable *** implement the micro-supercapacitors in various practical applications that can accompany solid state or gel electrolyte and flexible substrates,ions must be readily transported to electrodes for achieving high power ***,we show large enhancement in electrochemical properties of flexible,inplane micro-supercapacitor using sharp-edged interdigitated electrode design,which was simply fabricated through direct laser scribing *** sharp-edged electrodes allowed strong electric field to be induced at the corners of the electrode fingers which led to the greater accumulation of ions near the surface of electrode,significantly enhancing the energy storage performance of *** electric field-enhanced in-plane micro-supercapacitor showed the volumetric energy density of 1.52 Wh L^(−1)and the excellent cyclability with capacitive retention of 95.4%after 20000 *** further showed various practicability of our sharp-edged design in micro-supercapacitors by showing circuit applicability,mechanical stability,and air *** results present an important pathway for designing electrodes in various energy storage devices.

关键词： electric field enhancement flexible energy storage device microsupercapacitors sharp electrodes

三孩政策下已婚人群的再生育意愿研究——基于数量和确定性视角的分析

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中国人口科学 2024年第2期38卷 82-97页

作者：卿石松温敏华东师范大学社会发展学院

在当前低生育率背景下,精确评估生育意愿尤为重要。文章在明确区分“生育意愿”与“生育愿望”的基础上,从数量和确定性两个维度综合评估已婚人群的再生育意愿强度。研究结果表明,大多数人倾向于拥有两个孩子(理想子女数),但实际的再生... 详细信息

在当前低生育率背景下,精确评估生育意愿尤为重要。文章在明确区分“生育意愿”与“生育愿望”的基础上,从数量和确定性两个维度综合评估已婚人群的再生育意愿强度。研究结果表明,大多数人倾向于拥有两个孩子(理想子女数),但实际的再生育意愿较低且存在较大的不确定性。即使只有一个孩子且未实现生育愿望,有意再生育一个或更多孩子的比例也很低,近半数人确定不再生育,其余人则处于“可能不生”或“尚未决定”的犹豫状态。这揭示了人们在现实因素的制约性下陷入既想生又不敢生的矛盾状态,凸显不确定性在生育意愿中的重要作用。此外,生育愿望、现有子女数与再生育意愿之间存在互动关联。未满足的子女数量愿望增加不确定的意愿,且能激发积极的再生育意愿。未满足的男孩偏好也能够推动二孩家庭更高孩次的生育意愿。文章为生育意愿的测量指标与方法提供了新的框架,也为理解生育意愿的形成和实现机制提供了理论和政策依据。

关键词：生育愿望再生育意愿不确定性性别偏好