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国际医学放射学杂志 2013年第4期 382-382页

作者： G. Verma J.H. woo S. Chawla S. Wang S. Sheriff L.B. Elman 董龙春 Departments of Radiology Hospital of the University of PennsylvaniaB6 Blockley Hall423 Guardian Dr Philadelphia PA 19104

目的应用平面回波波谱成像全脑分析检测肌萎缩性侧索硬化症(ALS)病人的脑局部代谢差异。材料与方法 16例(男9例,女7例,平均年龄56.6岁)ALS病人,5例(男4例,女1例,平均年龄62.6岁)可疑ALS病人和10名健康对照受试者(男5名,女5名,平均年龄5... 详细信息

目的应用平面回波波谱成像全脑分析检测肌萎缩性侧索硬化症(ALS)病人的脑局部代谢差异。材料与方法 16例(男9例,女7例,平均年龄56.6岁)ALS病人,5例(男4例,女1例,平均年龄62.6岁)可疑ALS病人和10名健康对照受试者(男5名,女5名,平均年龄56.1岁)在签署知情同意书后行平面回波波谱成像。本研究经机构审查委员会批准并符合HIPAA。应用代谢物成像和数据分析系统软件进行数据分析,将代谢物图与标准脑模板进行匹配。应用自动化解剖标记软件将肌酸(Cr)、胆碱(cho)和N-乙酰天门冬氨酸(NAA)的代谢图分割成81个区域以测量ALS病人的全脑代谢变化。统计分析采用非配对、无校正的双向Student t检验。结果 ALS病人6个区域的NAA/cho值较对照组显著降低,平均为23%(P≤0.01)。这些区域包括尾状核、舌回、缘上回及右、左上和右下枕叶。ALS病人8个区域的NAA/Cr值显著降低(P≤0.01),平均为16%。这些区域包括尾状核、楔叶、额下岛盖、颞横回、中央前回、罗兰迪克岛盖和上、下枕叶。患病组与对照组的cho/Cr值在任何区域均无显著差异。结论平面回波波谱成像全脑分析可实现对ALS病人脑局部代谢异常的检测,不仅包括运动皮质,而且还包括一些病生理发现ALS累及的其他区域。

关键词：肌萎缩性侧索硬化症全脑 ALS 应用平面波谱成像回波

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International guideline on natural orifice specimen extraction surgery(NOSES)for colorectal cancer(2023 version)

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Holistic Integrative Oncology 2023年第1期2卷 93-100页

作者： Zheng Liu Xu Guan Mingguang Zhang Xiyue Hu Ming Yang Junge Bai Jun Li Shaojun Yu Kefeng Ding Qingsi He Liang Kang Dan Ma Chuangang Fu Junhong Hu Ye Wei Donghui Sun Gang Yu Songbing He Changyou Wang Yanwei Gao Guiyu Wang Hongliang Yao Jian Peng Yangchun Zheng Bo Jiang Taiyuan Li Zhiguo Xiong Xuejun Sun Zhenning Wang William Meng William Tzu-Liang Chen Ming-Yin Shen John H.Marks Charles A.Ternent Darcy DShaw Jim SKhan Petr Tsarkov Inna Tulina Sergey Efetov Joaquim Manuel da Costa Pereira Fernanda Nogueira Ricardo Escalante Joel Leroy Avanish Saklani Audrius Dulskas Cuneyt Kayaalp Atsushi Nishimura Kay Uehara woo-Yong Lee Sang-Hoo Kim Suk-Hwan Lee Xishan Wang Committee of Colorectal Cancer Society Chinese Anti-Cancer Association International NOSES Alliance Department of Colorectal Surgery National Cancer CenterNational Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100021China Department of Colorectal Surgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of General Surgery Shandong University Qilu HospitalJinanShandongChina Department of Colorectal Surgery The Sixth Affiliated HospitalSun Yat-Sen UniversityGuangzhouChina Department of General Surgery Xinqiao HospitalThird Military Medical UniversityChongqingChina Department of Gastrointestinal Surgery Shanghai East HospitalTongji University School of MedicineShanghaiChina Department of Anorectal Surgery First Affiliated HospitalZhengzhou UniversityZhengzhouHenanChina Department of General Surgery Zhongshan HospitalFudan UniversityShanghaiChina Department of Gastric and Colorectal Surgery Jilin University First HospitalChangchunChina Department of General Surgery Qilu Hospital(Qingdao)Cheeloo College of MedicineShandong UniversityJinanChina Department of General Surgery the First Affiliated Hospital of Soochow UniversitySuzhouJiangsuChina Affiliated Hospital of North China University of Science and Technology TangshanHebeiChina Inner Mongolia Autonomous Region People’s Hospital HuhhotInner Mongolia Autonomous RegionChina Department of Colorectal Cancer Surgery the Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangChina Department of General Surgery The Second Xiangya HospitalCentral South UniversityChangshaHunanChina Department of General Surgery Xiangya HospitalCentral South UniversityChangshaChina Department of Gastrointestinal Surgery Sichuan Cancer HospitalChengduChina Department of Colorectal and Anal Surgery Shanxi Cancer HospitalTaiyuanShanxiChina Department of General Surgery The First Affiliated Hospital of Nanchang UniversityNanchangChina Department of Gastrointestinal Surgery Hubei Provincial Cancer Hosp

Purpose In recent years,natural orifice specimen extraction surgery(NOSES)has gained widespread attention as an alternative *** the safety and feasibility of NOSES have been well documented,many questions remain open for *** aim of this guideline is to provide more evidence for the promotion of *** This guideline has been prepared by the CACA Committee of Colorectal Cancer Society and the International NOSES Alliance,based on the latest *** The guideline on NOSES for colorectal cancer include the definition,classification,technology requirement,indications,technical difficulties and clinical *** The guideline provides a full introduction of the theoretical and technical aspects of NOSES for colorectal cancer which will beneficial to development of NOSES.

关键词： Colorectal cancer Guideline Treatment Surgery Holistic integrative medicine Natural orifice specimen extraction surgery

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