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Hepatobiliary & Pancreatic Diseases International 2023年第5期22卷 537-540页

作者： Sang-Hoon Kim Deok-Bog moon Woo-Hyoung Kang Dong-Hwan Jung sung-Gyu Lee Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical Center and University of Ulsan College of Medicine88 Olympic-ro 43-gilSongpa-guSeoul 05505Korea

Portal vein thrombosis(PVT)is no longer a definitive contraindication in liver transplants(LTs)[1].Complex vascular reconstructions such as cavoportal hemitransposition(CPHT)[2–5],renoportal anastomosis(RPA)[6,7],and use of sizable collaterals(pericholedochal varix[8,9],coronary vein,peripancreatic or perigastroesophageal varices[10],right superior colic vein[11],ileocolic vein[12],and left gastric vein[13]),or combined liverpancreas-small bowel transplant[14]are required for portal inflow in patients with total portosplenomesenteric thrombosis.

关键词： thrombosis anastomosis portal

Interstitial lung disease induced by the roots of Achyranthes japonica Nakai:Three case reports

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World Journal of Clinical Cases 2021年第8期9卷 2015-2021页

作者： Do-Sik moon sung-Ho Yoon Seung-Il Lee Sang-Gon Park Yong-Sub Na Department of Pulmonology and Critical Care Medicine Chosun University HospitalGwangju 61453South Korea Department of Internal Medicine Hemato-OncologyChosun University HospitalGwangju 61453South Korea

BACKGROUND The roots of Achyranthes japonica Nakai(AJN),called“Useul-puli,”has been traditionally used to control pain and improve dysfunction in osteoarthritis patients in South *** SUMMARY We described 3 patients diagnosed with herbal medicine induced interstitial lung disease after consuming boiled the roots of *** were referred to our hospital because of the modified Medical Research Council grade 4 *** computed tomography showed bilateral ground-glass opacities with patchy *** treatment with systemic glucocorticoid therapy and discontinuation of the roots of AJN,their symptoms improved,and almost all ground-glass opacities and patchy consolidations on chest radiography and chest computed tomography *** We present three cases of interstitial lung disease induced by the roots of AJN.

关键词： Herb Interstitial lung disease Achyranthes japonica Nakai Case report

Early bifurcation of hepatic artery in right-sided living-donor hepatectomy at Asan Medical Center: rarely a critical issue

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Hepatobiliary Surgery and Nutrition 2024年第3期13卷 520-522页

作者： Deok-Bog moon Gil-Chun Park Sang Hoon Kim sung-Min Kim Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea

In living donor liver transplantation(LDLT),early bifurcation of hepatic artery(HA)relative to the cutting line of bile duct(BD)requires additional skeletonization of the hilar plate,especially around BD,compared to opposite ***,it may preclude higher chances of biliary complications such as bile leak and biliary stenosis in the ***,donor surgeons should be well aware of the anatomical correlations among HA,BD,and portal vein(PV),based on preoperative 3-dimensional(3D)images,and also intraoperatively perform meticulous dissection of HA from the surrounding tissues and minimize the damage of microcirculation to the BD without using energy devices such as electrocautery(1).When extensive dissection around BD&its ischemic damage in the donor is expected to obtain single HA opening of the harvesting graft,we prefer separate two HA openings including right anterior and posterior HAs to single right HA(RHA)opening without skeletonization of donor’s BD.

关键词： Living donor liver transplantation(LDLT) hepatic artery(HA) early bifurcation right-sided living-donor

Morbidity analysis of left hepatic trisectionectomy for hepatobiliary disease and live donor

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Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 362-369页

作者： Young-In Yoon sung-Gyu Lee Deok-Bog moon Shin Hwang Ki-Hun Kim Hui-Ju Kim Ki-Hoon Choi Division of Hepatobiliary Surgery and Liver Transplantation Department of SurgeryAsan Medical CenterUniversity of Ulsan College of Medicine388-1 Poongnap-dongSongpa-guSeoul 138-736Korea Department of Surgery Gold Coast University HospitalSouthportQLD 4215Australia

Background:Despite remarkable advances in surgical techniques and perioperative management,left hepatic trisectionectomy(LHT)remains a challenging procedure with a somewhat high postoperative morbidity rate compared with less-extensive *** study aimed to analyze the short-and long-term outcomes of LHT and identify factors associated with the postoperative morbidity of this technically demanding surgical ***:The medical records of 53 patients who underwent LHT between June 2005 and October 2019 at a single institution were retrospectively *** independent prognostic factor of postoperative morbidity was analyzed using the logistic regression ***:Hepatocellular carcinoma was the most common indication for surgery(n=21),followed by hilar cholangiocarcinoma(n=14),intrahepatic cholangiocarcinoma(n=10),and other pathologies(including colorectal liver metastasis,hepatolithiasis,gallbladder cancer,living donor,hemangioma,and multilocular biliary cyst;n=8).The rates of postoperative morbidities of Clavien-Dindo grade 3 or higher and 90-day mortality were 39.6% and 1.9%,*** 1-,3-,and 5-year overall survival rates were 81.1%,61.4%,and 44.6%,*** analysis revealed that preoperative jaundice[hazard ratio(HR)=6.15,95%confidence interval(CI):1.57-24.17,P=0.009]and operative time>420 min(HR=4.66,95%CI:1.27–17.17,P=0.021)were independent predictors of postoperative ***:The in-hospital mortality of LHT surgery can be minimalized by a reliable preoperative evaluation of liver function and selection of the dominant anatomic features of right posterior sector,active and appropriate preoperative management for obstructive cholangitis and compensatory hypertrophy of the future remnant posterior sector,and the experience of the surgeon.

关键词： Left hepatic trisectionectomy Major hepatectomy Liver neoplasms Survival rate Morbidity

Effects of vagus nerve preservation and vagotomy on peptide YY and body weight after subtotal gastrectomy

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World Journal of Gastroenterology 2012年第30期18卷 4044-4050页

作者： Hyung Hun Kim Moo In Park Sang Ho Lee Hyun Yong Hwang sung Eun Kim Seun Ja Park Won moon Departments of Internal Medicine Kosin University College of MedicineBusan 602-702South Korea Departments of Surgery Kosin University College of MedicineBusan 602-702South Korea Departments of Laboratory Medicine Kosin University College of MedicineBusan 602-702South Korea

AIM:To investigate the relationship between the function of vagus nerve and peptide YY 3-36 and ghrelin levels after subtotal ***:We enrolled a total of 16 patients who underwent subtotal gastrectomy due to gastric *** surgeries were performed by a single skilled *** measured peptide YY 3-36,ghrelin,leptin,insulin,growth hormone levels,and body weight immediately before and one month after ***:Vagus nerve preservation group showed less body weight loss and less increase of peptide YY 3-36 compared with vagotomy group(-5.56 ± 2.24 kg vs-7.85 ± 1.57 kg,P = 0.037 and 0.06 ± 0.08 ng/mL vs 0.19 ± 0.12 ng/mL,P = 0.021,respectively).Moreover,patients with body weight loss of less than 10% exhibited reduced elevation of peptide YY 3-36 level,typically less than 20% [6(66.7%) vs 0(0.0%),P = 0.011,odd ratio = 3.333,95% confidence interval(1.293,8.591)].CONCLUSION:Vagus nerve preservation contributes to the maintenance of body weight after gastrectomy,and this phenomenon may be related to the suppressed activity of peptide YY 3-36.

关键词： Peptide YY Ghrelin Vagotomy Gastrectomy Body weight

Changes in structural plasticity of hippocampal neurons in an animal model of multiple sclerosis

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Zoological Research 2024年第2期45卷 398-414页

作者： Poornima D.E.Weerasinghe-Mudiyanselage Sohi Kang Joong-Sun Kim sung-Ho Kim Hongbing Wang Taekyun Shin Changjong moon Department of Veterinary Anatomy and Animal Behavior College of Veterinary Medicine and BK21 FOUR ProgramChonnam National UniversityGwangju 61186Republic of Korea Department of Anatomy and Convergence Medical Science Institute of Health SciencesCollege of MedicineGyeongsang National UniversityJinju 52727Republic of Korea Department of Physiology and Neuroscience Program Michigan State UniversityEast LansingMI 48824USA Department of Veterinary Anatomy College of Veterinary Medicine and Veterinary Medical Research InstituteJeju National UniversityJeju 63243Republic of Korea

Structural plasticity is critical for the functional diversity of neurons in the *** autoimmune encephalomyelitis(EAE)is the most commonly used model for multiple sclerosis(MS),successfully mimicking its key pathological features(inflammation,demyelination,axonal loss,and gliosis)and clinical symptoms(motor and non-motordysfunctions).Recentstudieshave demonstrated the importance of synaptic plasticity in EAE *** the present study,we investigated the features of behavioral alteration and hippocampal structural plasticity in EAE-affected mice in the early phase(11 days post-immunization,DPI)and chronic phase(28DPI).EAE-affected mice exhibited hippocampus-related behavioral dysfunction in the open field test during both early and chronic *** complexity was largely affected in the cornu ammonis 1(CA1)and CA3 apical and dentate gyrus(DG)subregions of the hippocampus during the chronic phase,while this effect was only noted in the CA1 apical subregion in the early ***,dendritic spine density was reduced in the hippocampal CA1 and CA3 apical/basal and DG subregions in the early phase of EAE,but only reduced in the DG subregion during the chronic ***,mRNA levels of proinflammatory cytokines(Il1β,Tnfα,and Ifnγ)and glial cell markers(Gfap and Cd68)were significantly increased,whereas the expression of activity-regulated cytoskeletonassociated protein(ARC)was reduced during the chronic ***,exposure to the aforementioned cytokines in primary cultures of hippocampal neurons reduced dendritic complexity and ARC *** cultures of hippocampal neurons also showed significantly reduced extracellular signal-regulated kinase(ERK)phosphorylation upon treatment with proinflammatory ***,these results suggest that autoimmune neuroinflammation alters structural plasticity in the hippocampus,possibly through the ERK-ARC pathway,indicating that this alteration may be associated with hi

关键词： Activity-regulated cytoskeleton-associated protein Anxiety-like behavior Experimental autoimmune encephalomyelitis Hippocampal dysfunction Neuroinflammation

Enhancing ammonia production rates from electrochemical nitrogen reduction by engineering three-phase boundary with phosphorus-activated Cu catalysts

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Journal of Energy Chemistry 2023年第9期84卷 394-401页

作者： Jeehye Kim Cho Hee Lee Yong Hyun moon Min Hee Lee Eun Hyup Kim Sun Hee Choi Youn Jeong Jang Jae sung Lee School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea Department of Chemical Engineering Hanyang UniversitySeoul 04763Republic of Korea Pohang Accelerator Laboratory(PAL) Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea

Electrochemical N_(2) reduction reaction(eNRR) over Cu-based catalysts suffers from an intrinsically low activity of Cu for activation of stable N_(2) molecules and the limited supply of N_(2) to the catalyst due to its low solubility in aqueous ***,we propose phosphorus-activated Cu electrocatalysts to generate electron-deficient Cu sites on the catalyst surface to promote the adsorption of N_(2) *** eNRR system is further modified using a gas diffusion electrode(GDE) coated with polytetrafluoroethylene(PTFE) to form an effective three-phase boundary of liquid water-gas N_(2)-solid catalyst to facilitate easy access of N_(2) to the catalytic *** a result,the new catalyst in the flow-type cell records a Faradaic efficiency of 13.15% and an NH_(3) production rate of 7.69 μg h^(-1) cm^(-2) at-0.2 V_(RHE),which represent 3.56 and 59.2 times increases from those obtained with a pristine Cu electrode in a typical electrolytic *** work represents a successful demonstration of dual modification strategies;catalyst modification and N_(2) supplying system engineering,and the results would provide a useful platform for further developments of electrocatalysts and reaction systems.

关键词： Electrochemical nitrogen reduction reaction Ammonia production Phosphorous modified copper electrodes Gas diffusion electrodes Three-phase boundary PTFE coating

Influence of tool plunge depth and welding distance on friction stir lap welding of AA5454-O aluminum alloy plates with different thicknesses

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中国有色金属学会会刊：英文版 2012年第S3期22卷 624-628页

作者： Jun-Won KWON Myoung-Soo KANG sung-Ook YOON Yong-Jai KWON sung-Tae HONG Dae-Il KIM Kwang-Hak LEE Jong-Dock SEO Jin-Soo moon Kyung-Sik HAN School of Materials Science and Engineering University of Ulsan School of Mechanical Engineering University of Ulsan Technical Research Laboratories Shin Young Co.Ltd. Automotive Parts Innovation Center Ulsan Technopark

AA5454-O aluminum alloy plates with thicknesses of 1.4 and 1.0 mm were friction-stir-lap-welded (FSLWed).The influences of the tool plunge depth and welding distance on surface appearance,macrostructure and mechanical properties of the FSLWed plates were experimentally *** tensile shear load of the FSLWed plates was compared with that of the adhesive-bonded ***-free FSLWed zones were successfully obtained in all the tool plunge depths and the welding *** FSLWed zones exhibited the relatively smooth surface *** all the FSLWed conditions,the FSLWed zone exhibited higher average hardness than the base *** addition,the upper plate exhibited a higher average hardness than the lower plate,although there was no special tendency in spite of the change in the tool plunge depth and the welding *** maximum tensile shear load of the FSLWed plates was much higher than that of the adhesive-bonded aluminum alloy ***,under the FSLW condition of the plunge depth of 1.8 mm and the welding distance of 40 mm,the tensile shear load of the FSLWed plate reached a level about 41% greater than that of the adhesive-bonded aluminum alloy *** addition,the maximum tensile shear load of the FSLWed plate was increased with the increase of the welding distance.

关键词： friction stir lap welding AA5450-O aluminum alloy tool plunge depth welding distance mechanical properties

Acute kidney injury due to intravenous detergent poisoning:A case report

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World Journal of Clinical Cases 2022年第6期10卷 2036-2044页

作者： sungbin Park Hyun-Sik Ryu Jae-Kwang Lee sung-Soo Park Sun-Jung Kwon Won-Min Hwang sung-Ro Yun moon-Hyang Park Yohan Park Department of Internal Medicine Division of NephrologyKonyang University HospitalCollege of MedicineDaejeon 35365South Korea Department of Emergency Medicine Konyang University HospitalCollege of MedicineDaejeon 35365South Korea Department of Internal Medicine Division of Respiratory and Critical Care MedicineKonyang University HospitalCollege of MedicineDaejeon 35365South Korea Department of Pathology Konyang University HospitalCollege of MedicineDaejeon 35365South Korea

BACKGROUND Detergent poisoning mostly occurs through oral ingestion(>85%),ocular exposure(<15%),or dermal exposure(<8%).Reports of detergent poisoning through an intravenous injection are extremely *** addition,there are very few cases of renal toxicity directly caused by ***,we report a unique case of acute kidney injury caused by detergent poisoning through an accidental intravenous *** SUMMARY A 61-year-old man was intravenously injected with 20 mL of detergent by another patient in the same room of a local *** surfactant and calcium carbonate accounted for the largest proportion of the *** patient complained of vascular pain,chest discomfort,and nausea,and was transferred to our *** hospitalization,the patient’s serum creatinine level increased to 5.42 mg/dL,and his daily urine output decreased to approximately 300 *** biopsy findings noted that the glomeruli were relatively intact;however,diffuse acute tubular injury was *** edema was also noted,and the patient underwent a total of four hemodiafiltration ***,the patient’s urine output gradually increased whereas the serum creatinine level *** patient was discharged in a stable status without any *** Detergents appear to directly cause renal tubular injury by systemic *** treating a patient with detergent poisoning,physicians should be aware that the renal function may also *** addition,timely renal replacement therapy may help improve the patient’s prognosis.

关键词： Detergents Poisoning Intravenous injection Acute kidney injury Acute tubular injury Case report

Coherent interface driven super-plastic elongation of brittle intermetallic nano-fibers at room temperature

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Journal of Materials Science & Technology 2022年第20期115卷 97-102页

作者： Eun-Ae Choi Seung Zeon Han Hyung Giun Kim Jee Hyuk Ahn sung Hwan Lim Sangshik Kim Nong-moon Hwang Kwangho Kim Jehyun Lee Department of Special Alloy Korea Institute of Materials ScienceChangwon 642-831Korea Gangwon Regional Division Korea Institute of Industrial TechnologyGangneung 210-340Korea Department of Advanced Materials Science&Engineering Kangwon National UniversityChuncheon 200-701Korea Department of Materials Science and Engineering ReCAPTGyeongsang National UniversityChinju 660-701Korea Department of Materials Science and Engineering Seoul National UniversitySeoul 151-744Korea Department of Materials Science and Engineering Pusan National UniversityBusan 46241Korea Department of Materials Science and Engineering Changwon National UniversityChangwon 641-773Korea

The intermetallic compound such as Ni_(2)Si has a brittle ***,monolithic intermetallic compounds have not yet been prepared by mechanical *** mechanical drawing of bulk CuNi_(2)Si alloy at room temperature,we observed more than 400%plastic elongation of hard and brittle Ni_(2)Si intermetallic *** calculation based on the density functional theory reveals that the fully coherent interface induces strain on the intermetallic compound surrounded by the matrix,and lowers the intrinsic stacking fault energy below the level required to break an interatomic *** new interface between the Ni_(2)Si intermetallic and Cu matrix formed by the plastic deformation is as stable as the original coherent interface formed by precipitation,and the activation energy of the newly formed interface to slip is similar to that of the Cu *** of these make plastic deformation of brittle Ni_(2)Si intermetallic possible by slip without failure.

关键词： Ni_(2)Si Intermetallic compound Plastic deformation Precipitation Brittle fiber Interface Density functional theory