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Estimation of marine winds in and around typhoons using multi-platform satellite observations: Application to Typhoon Soulik (2018)

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Frontiers of Earth Science 2022年第1期16卷 175-189页

作者： Seung-Woo LEE sung hyun nam Duk-Jin KIM School of Earth and Environmental Sciences College of Natural SciencesSeoul National UniversitySeoul 08826Republic of Korea Research Institution of Oceanography College of Natural SciencesSeoul National UniversitySeoul 08826Republic of Korea

Estimating horizontal winds in and around typhoons is important for improved monitoring and prediction of typhoons and mitigating their ***,we present a new algorithm for estimating typhoon winds using multiple satellite observations and its application to Typhoon Soulik(2018).Four kinds of satellite remote sensing data,along with their relationship to typhoon intensity,derived statistically from hundreds of historical typhoon cases,were merged into the final product of typhoon wind(MT wind):(1)geostationarysatellite-based infrared images(IR wind),(2)passive microwave sounder(MW wind),(3)feature-tracked atmospheric motion vectors,and (4)scatterometer-based sea surface winds(SSWs).The algorithm was applied to two cases(A and B)of Typhoon Soulik and validated against SSWs independently retrieved from active microwave synthetic aperture radar(SAR)and microwave radiometer(AMSR2)images,and vertical profiles of wind speed derived from reanalyzed data and dropsonde *** Case A(open ocean),the algorithm estimated the realistic maximum wind,radius of maximum wind,and radius of 15 m/s,which could not be estimated using the reanalysis data,demonstrating reasonable and practical ***,for Case B(when the typhoon rapidly weakened just before making landfall in the Korean Peninsula),the algorithm significantly overestimated the parameters,primarily due to the overestimation of typhoon *** study highlights that realistic typhoon winds can be monitored continuously in real-time using multiple satellite observations,particularly when typhoon intensity is reasonably well predicted,providing timely analysis results and products of operational importance.

关键词： sea surface wind multi-platform satellites Typhoon Soulik(2018)

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Survival benefit of concurrent chemoradiotherapy for advanced ampulla of Vater cancer

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World Journal of Clinical Cases 2024年第2期12卷 267-275页

作者： Chae Hwa Kwon hyung Il Seo Dong Uk Kim sung Yong Han Suk Kim nam Kyung Lee Seung Baek Hong Ji hyun Ahn Young Mok Park Byeong Gwan Noh BioMedical Research Institute Pusan National University HospitalBusan 49241South Korea Department of Surgery Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Internal Medicine Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Radiology Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Pathology and Biomedical Research Institute Pusan National University HospitalBusan 49241South Korea

BACKGROUND Currently,there is no standard adjuvant therapy for patients with resected ampulla of Vater(AoV)*** To evaluate the effectiveness of adjuvant concurrent chemoradiotherapy(CCRT)in patients with advanced AoV cancer who underwent curative *** This single-centered,retrospective study included 29 patients with advanced AoV cancer who underwent pancreaticoduodenectomy between 2006 and *** impact of CCRT on advanced AoV cancer was *** The 1-,3-,and 5-yr recurrence-free survival(RFS)rates for patients with advanced AoV cancer were 82.8%,48.3%,and 40.8%,respectively,and the overall survival(OS)rates were 89.7%,62.1%,and 51.7%,***-cular invasion was found to be a significant risk factor for RFS and OS in patients with advanced AoV cancer in the univariate analysis,whereas T stage and lymph node metastasis were significantly associated with OS in the multivariate *** to the patients who did not receive adjuvant CCRT,those who received adjuvant CCRT did not show statistically significant improvements in the RFS and OS,although they had a significantly lower average age and significantly higher platelet-to-lymphocyte *** Adjuvant CCRT did not improve survival outcomes in patients with advanced AoV *** findings contribute to existing knowledge on the effectiveness of CCRT in this patient population and provide important insights for clinical decision-making.

关键词： Advanced ampulla of Vater cancer Adjuvant concurrent chemoradiotherapy Recurrence Survival Vater cancer

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Catalpa bignonioides extract improves exercise performance through regulation of growth and metabolism in skeletal muscles

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Asian Pacific Journal of Tropical Biomedicine 2024年第2期14卷 47-54页

作者： Hoibin Jeong Dong-joo Lee sung-Pil Kwon SeonJu Park Song-Rae Kim Seung hyun Kim Jae-Il Park Deug-chan Lee Kyung-Min Choi WonWoo Lee Ji-Won Park Bohyun Yun Su-Hyeon Cho Kil-nam Kim Seoul Center Korea Basic Science InstituteSeoul 02841Republic of Korea Chuncheon Center Korea Basic Science InstituteChuncheon 24341Republic of Korea Research&Development Center Chungdam CDC JNPharm LLC.Chuncheon 24341Republic of Korea Department of Biomedical Technology Kangwon National UniversityChuncheon 24341Republic of Korea Yonsei Institute of Pharmaceutical Sciences College of PharmacyYonsei UniversityIncheon 21983Republic of Korea Gwangju Center Korea Basic Science InstituteGwangju 61751Republic of Korea Honam National Institute of Biological Resources 99Gohadoan-gilMokpo-siJeollanam-do58762Republic of Korea Department of Bio-analysis Science University of Science&TechnologyDaejeon34113Republic of Korea

Objective:To evaluate the effects of Catalpa bignonioides fruit extract on the promotion of muscle growth and muscular capacity in vitro and in ***:Cell viability was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** proliferation was assessed using a 5-bromo-2’-deoxyuridine(BrdU)assay *** blot analysis was performed to determine the protein expressions of related *** effects of Catalpa bignonioides extract were investigated in mice using the treadmill exhaustion test and whole-limb grip strength *** composition analysis was performed using high-performance liquid chromatography(HPLC).Results:Catalpa bignonioides extract increased the proliferation of C2C12 mouse myoblasts by activating the Akt/mTOR signaling *** also induced metabolic changes,increasing the number of mitochondria and glucose metabolism by phosphorylating adenosine monophosphate-activated protein *** an in vivo study,the extract-treated mice showed improved motor abilities,such as muscular endurance and grip ***,HPLC analysis showed that vanillic acid may be the main component of the Catalpa bignonioides extract that enhanced muscle ***:Catalpa bignonioides improves exercise performance through regulation of growth and metabolism in skeletal muscles,suggesting its potential as an effective natural agent for improving muscular strength.

关键词： Catalpa bignonioides Skeletal muscle Cell proliferation Mitochondria Energy metabolism C2C12

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Realizing High Thermoelectric Performance in n-Type Se-Free Bi2Te3 Materials by Spontaneous Incorporation of FeTe2 Nanoinclusions

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Energy & Environmental Materials 2024年第4期7卷 344-354页

作者： Jamil Ur Rahman Woo hyun nam Yong-Jae Jung Jong Ho Won Jong-Min Oh Nguyen Van Du Gul Rahman Víctor M.García-Suárez Ran He Kornelius Nielsch Jung Young Cho Won-Seon Seo Jong Wook Roh Sang-il Kim Soonil Lee Kyu Hyoung Lee hyun Sik Kim Weon Ho Shin Leibniz Institute for Solid State and Materials Research Advanced Materials Convergence R&D Division Korea Institute of Ceramic Engineering & Technology Department of Electronic Materials Engineering Kwangwoon University Department of Energy Engineering Dankook University Faculty of Fundamental Science Phenikaa University Department of Physics Quaid-i-Azam University Departamento de Física Universidad de Oviedo Nanomaterials and Nanotechnology Research Center-CINN Department of Materials Science and Engineering Yonsei University School of Nano & Materials Science and Engineering Kyungpook National University Department of Materials Science and Engineering University of Seoul School of Materials Science and Engineering Changwon National University

Bi2Te3-based materials have drawn much attention from the thermoelectric community due to their excellent thermoelectric performance near room ***,the stability of existing n-type Bi2（Te,Se）3materials is still low due to the evaporation energy of Se (37.70 kJ mol-1) being much lower than that of Te (52.55 kJ mol-1).The evaporated Se from the material causes problems in interconnects of the module while degrading the efficiency.

关键词： Bi2Te3 energy harvesting FeTe2 nanoinclusion n-type materials thermoelectric

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Usefulness of artificial intelligence in gastric neoplasms

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World Journal of Gastroenterology 2021年第24期27卷 3543-3555页

作者： Ji hyun Kim Seung-Joo nam sung Chul Park Division of Gastroenterology and Hepatology Department of Internal MedicineKangwon National University School of MedicineChuncheon 24289Kangwon DoSouth Korea

Recently,studies in many medical fields have reported that image analysis based on artificial intelligence(AI)can be used to analyze structures or features that are difficult to identify with human *** diagnose early gastric cancer,related efforts such as narrow-band imaging technology are ***,diagnosis is often ***,a diagnostic method based on AI for endoscopic imaging was developed and its effectiveness was confirmed in many *** gastric cancer diagnostic program based on AI showed relatively high diagnostic accuracy and could differentially diagnose non-neoplastic lesions including benign gastric ulcers and *** AI system has also been developed that helps to predict the invasion depth of gastric cancer through endoscopic images and observe the stomach during endoscopy without blind ***,if AI is used in the field of endoscopy,it is expected to aid in the diagnosis of gastric neoplasms and determine the application of endoscopic therapy by predicting the invasion depth.

关键词： Artificial intelligence Convolutional neural network Gastric neoplasm Esophagogastroduodenoscopy Diagnosis Invasion depth

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Reliability, Accuracy, and Use Frequency of Evaluation Methods for Amount of Tongue Coating

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Chinese Journal of Integrative Medicine 2019年第5期25卷 378-385页

作者： Su-Ryun Kim Dong-hyun nam Department of Biofunctional Medicine and Diagnosis College of Korean MedicineSangji UniversityWonju 26339Republic of Korea

Objective: To classify the evaluation methods for amount of tongue coating(TC) and investigate their reliability, accuracy, and frequency of use. Methods: Articles published from 1985 to 2015 were searched for evaluation methods for the amount of TC in PubMed and the Cochrane Library. Only clinical researches were included except protocol articles. The methods were classi?ed according to their characteristics. Results: Finally,113 articles were selected. The evaluation method for the amount of TC from the articles was classi?ed into 4 types: intuitive, specificative, computerized, and weighing TC. The reliability in the intuitive and specificative methods(κ=0.33–0.92) showed varying levels among the studies. In general, the amount of TC calculated by the speci?cative method(Spearman's r=0.68–0.80) was more strongly related to the directly measured value than to the value estimated by the computerized method(Pearson's r=0.442). The number of articles published on this topic has increased consistently, and the speci?cative method was the most frequently used. Despite the higher reliability of the computerized method, it has not been widely used. Conclusions: The high prevalence of the speci?cative method would continue in clinical practice because of its convenience and accuracy. However,to establish higher reliability, the limitation of the subjectivity of the assessors should be overcome through calibration training. In the computerized method, novel algorithms are needed to obtain a higher accuracy so that it can help the practitioners con?dently estimate the amount of TC.

关键词： tongue coating evaluation methods reliability accuracy frequency

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Void defect detection in ball grid array X-ray images using a new blob filter

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Journal of Zhejiang University-Science C(Computers and Electronics) 2012年第11期13卷 840-849页

作者： Shao-hu PENG hyun Do nam Department of Electronics and Electrical Engineering Dankook University

Ball grid arrays (BGAs) have been used in the production of electronic devices/assemblies because of their advantages of small size, high I/O port density, etc. However, BGA voids can degrade the performance of the board and cause failure. In this paper, a novel blob filter is proposed to automatically detect BGA voids presented in X-ray images. The proposed blob filter uses the local image gradient magnitude and thus is not influenced by image brightness, void position, or component interference. Different sized average box filters are employed to analyze the image in multi-scale, and as a result, the proposed blob filter is robust to void size. Experimental results show that the proposed method obtains void detection accuracy of up to 93.47% while maintaining a low false ratio. It outperforms another recent algorithm based on edge detection by 40.69% with respect to the average detection accuracy, and by 16.91% with respect to the average false ratio.

关键词： Ball grid array (BGA) X-ray Defect detection Blob detection Void detection

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Spin Self-Assembled Clay Nanocomposite Passivation Layers Made from a Photocrosslinkable Poly（vinyl alcohol） and Na^-Montmorillonite Enhance the Environmental Stability of Organic Thin-Film Transistors

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Chinese Journal of Chemistry 2016年第11期34卷 1103-1108页

作者： Hayoung Jeon Seonuk Park Sooji nam Kwonwoo Shin sung-Ryong Kim Se hyun Kim Jaeyoung Jang Tae Kyu An POSTECH Organic Electronics Laboratory Polymer Research Institute Department of Chemical Engineering Pohang University of Science and Technology Pohang 790-784 Republic of Korea Smart I/O Control Device Research Section Electronics and Telecommunications Research Institute Daejeon 305- 700 Republic of Korea Nano Materials & Components Research Center Korea Electronics Technology Institute (KET1) Seongsam-si Gyeonggi-do 13509 Republic of Korea Department of Polymer Science & Engineering Korea National University of Transportation 50 Daekak-Ro Chungju 27469 Republic of Korea School of Chemical Engineering Yeungnam University 280 Daehak-Ro Gyeongsan Gyeongbuk 38541 Republic of Korea Department of Energy Engineering Hanyang University Seoul 133-791 Republic of Korea

We investigated the effects of the multilayer polymer-clay nanohybrid passivation films on the stability of pentacene organic thin-film transistors （OTFTs） exposed to air and UV irradiation. Well-ordered multilayer films were deposited by the spin-assisted layer-by-layer assembly method using photocrosslinkable poly（vinyl alcohol） with the N-methyl-4（4＇-formylstyryl）pyridinium methosulfate acetal group （SbQ-PVA） and Na＋-montmorillonite in a water-based solution process. When photocrosslinked, these SbQ-PVA/clay multilayers were found to serve as excellent barriers to 02 and UV-light. Moreover, when used as passivation layers, they enhanced the stability of pen- tacene OTFT devices exposed to air and UV radiation.

关键词： polymer-clay passivation layer-by-layer montmorillonite long-term stability

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UBP12/UBP13-mediated deubiquitination of salicylic acid receptor NPR3 suppresses plant immunity

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Molecular Plant 2023年第1期16卷 232-244页

作者： Yu Zhou Su-hyun Park nam-Hai Chua Temasek Life Sciences Laboratory National University of Singapore1 Research LinkSingapore 117604Singapore Disruptive&Sustainable Technologies for Agricultural Precision Singapore-MIT Alliance for Research and Technology1 CREATE WaySingapore 138602Singapore

Salicylic acid(SA),a defense hormone produced after pathogen challenge,is critical for plant *** NONEXPRESSER OF PR GENES 1(NPR1)and its paralogs NPR3 and NPR4 can bind SA and mediate SA signal ***1 functions as a transcriptional co-activator to promote defense gene expression,whereas NPR3 and NPR4 have been shown to function as negative regulators in the SA signaling *** the mechanism about NPR1 regulation has been well studied,how NPR3/NPR4 proteins are regulated in immune responses remains largely ***,we show that the stability of NPR3/NPR4 is enhanced by *** the absence of pathogen challenge,NPR3/NPR4 are unstable and degraded by the 26S proteasome,whereas the increase in cellular SA levels upon pathogen infection suppresses NPR3/NPR4 *** found that UBP12 and UBP13,two homologous deubiquitinases from a ubiquitin-specific protease subfamily,negatively regulate plant immunity by promoting NPR3/NPR4 *** genetic results further showed that UBP12/UBP13-mediated immunity suppression is partially dependent on NPR3/NPR4 *** interacting with NPR3 in the nucleus in an SA-dependent manner,UBP12 and UBP13 remove ubiquitin from polyubiquitinated NPR3 to protect it from being *** stabilization of NPR3/NPR4 promoted by UBP12/UBP13 is essential for negative regulation of basal and SA-induced immunity.

关键词： plant immunity salicylic acid NPR3 UBP12/UBP13

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Sorption enhanced catalytic CF4 hydrolysis with a three-stage catalyst-adsorbent reactor

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Frontiers of Chemical Science and Engineering 2017年第4期11卷 537-544页

作者： Jae-Yun Han Chang-hyun Kim Boreum Lee sung-Chan nam Ho-Young Jung Hankwon Lim Kwan-Young Lee Shin-Kun Ryi . Advanced Materials and Devices Laboratory Korea Institute of Energy Research (KIER) Daejeon 34129 Korea.. Department of Advanced Materials and Chemical Engineering Catholic University of Daegu Gyeongbuk 38430 Korea.. Department of Environment and Energy Engineering Chonnam National University Gwangju 61186 Korea.. Department of Chemical and Biological Engineering Korea University Seoul 136-701 Korea

In this study, we developed a three-stage catalyst-adsorbent reactor for the catalytic hydrolysis of CF4. Each stage is composed of a catalyst bed followed by an adsorbent bed using Ca（OH）2 to remove HF. The three stages are connected in series to enhance the hydrolysis of CF4 and eliminate a scrubber to dissolve HF in water at the same time. With a 10 wt-% Ce/AlaO3 catalyst prepared by the incipient wetness method using boehmite and a granular calcium hydroxide as an adsorbent, the CF4 conversion in our proposed reactor was 7%-23% higher than that in a conventional single-bed catalytic reactor in the temperature range of 923-1023 K. In addition, experimental and numerical simulation （Aspen HYSYS） results showed a reasonable trend of increased CF4 conversion with the adsorbent added and these results can be used as a useful design guideline for our newly proposed multistage reactor system.

关键词： PFCs catalytic hydrolysis calcium hydro-xide sorption enhanced process simulation

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