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Evaluation of non-ampullary duodenal polyps: Comparison of non-neoplastic and neoplastic lesions

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World Journal of Gastroenterology 2010年第43期16卷 5474-5480页

作者： sung Hoon jung Woo Chul Chung eun jung Kim Seol Hye Kim Chang Nyol Paik Bo In Lee Young Seok Cho Kang-Moon Lee Department of Internal Medicine College of Medicine The Catholic University of Korea

AIM: To evaluate duodenal polyps, divided into nonneoplastic and neoplastic lesions. In addition, the clinical characteristics of duodenal hyperplastic polyps are determined. METHODS: We analyzed medical records of 50 114 consecutive patients submitted to for first diagnostic esophago-gastroduodenoscopy between January 2004 and December 2009. We excluded lesions on the ampulla of Vater and submucosal tumors. We studied 510 cases that were diagnosed endoscopically with duodenal polyps and enrolled a total of 221 cases that had undergone tissue biopsy. We analyzed the differences between non-neoplastic and neoplastic lesions, and determined the clinical features of duodenal hyperplastic polyps. RESULTS: Non-neoplastic lesions were found in 196 patients and neoplastic lesions in 25 patients. On uni-variate analysis, there were significant differences in shape, location, and size. Polyps more than 10 mm in diameter or polyps in the second portion had independent risk factors for being neoplastic lesions, as identified by multivariate analysis. In 23 cases of hyperplastic polyps (79.3%), they were accompanied by gastroduodenal pathology, which was possibly associated with Helicobacter pylori . CONCLUSION: Polyps of more than 10 mm or polyps in the second portion of the duodenum should be evaluated by histological examination.

关键词： Duodenum Polyp Helicobacter pylori

Intelligent Home Using Fuzzy Control Based on AIoT

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Computer Systems Science & Engineering 2023年第5期45卷 1063-1081页

作者： sung-jung Hsiao Wen-Tsai sung Department of Information Technology Takming University of Science and TechnologyTaipei City11451Taiwan China Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030Taiwan China

The Internet of Things has grown rapidly in recent years,and the technologies related to it have been widely used in various *** idea of this paper is to build a set of Internet of Things systems in a smart home wireless network environment,with the purpose of providing people with a more comfortable,convenient,and safe *** the sensing layer of the Internet of Things,we discuss the uses of common sensing technologies on the Internet and combine these with Arduino microprocessors to integrate temperature sensing modules,humidity sensing modules,gas sensing modules,and particulate matter 2.5(PM2.5)sensing *** the network layer,we discuss using the Wi-Fi wireless networking function composed of a home router and a wireless Wi-Fi chip Espressif system 8266(ESP8266)to transmit the collected home-sensing data to the ThingSpeak cloud ***,in the application layer part,the system uses a mobile device with fuzzy calculation optimization *** system is also connected remotely for home environment monitoring,so the home environment can be optimized anytime,anywhere.

关键词： Wireless sensor networks internet of things ESP8266 thingspeak fuzzy control

Segmented tomographic evaluation of structural degradation of carbon support in proton exchange membrane fuel cells

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Journal of Energy Chemistry 2022年第11期31卷 359-367,I0010页

作者： jung A.Hong Min-Hyoung jung sung Yong Cho eun-Byeol Park Daehee Yang Young-Hoon Kim Sang-Hyeok Yang Woo-sung Jang Jae Hyuck Jang Hyo June Lee sungchul Lee Hu Young Jeong Young-Min Kim Department of Energy Science Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea Fuel Cell Core Parts Development Cell Hyundai Mobis Co.Ltd.Uiwang 16082Republic of Korea Electron Microscopy&Spectroscopy Team Korea Basic Science Institute(KBSI)Daejeon 34133Republic of Korea Graduate School of Semiconductor Materials and Devices Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea

The variation of the three-dimensional(3D)structure of the membrane electrode of a fuel cell during proton exchange cycling involves the corrosion/compaction of the carbon *** increasing degradation of the carbon structure continuously reduces the electrocatalytic performance of proton exchange membrane fuel cells(PEM-FCs).This phenomenon can be explained by performing 3D tomographic analysis at the ***,conventional tomographic approaches which present limited experimental feasibility,cannot perform such evaluation and have not provided sufficient structural information with statistical significance thus ***,a reliable methodology is required for the 3D geometrical evaluation of the carbon ***,we propose a segmented tomographic approach which employs pore network analysis that enables the visualization of the geometrical parameters corresponding to the porous carbon structure at a high *** approach can be utilized to evaluate the 3D structural degradation of the porous carbon structure after cycling in terms of local surface area,pore size distribution,and their 3D *** geometrical parameters of the carbon body were demonstrated to be substantially reduced owing to the cycling-induced *** information enables a deeper understanding of the degradation phenomenon of carbon supports and can contribute to the development of stable PEM-FC electrodes.

关键词： Electron tomography Fuel cell Proton exchange membrane Membrane electrode assembly Carbon corrosion

Creating Smart House via IoT and Intelligent Computation

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Intelligent Automation & Soft Computing 2023年第1期35卷 415-430页

作者： Wen-Tsai sung sung-jung Hsiao Department of Electrical Engineering National Chin-Yi University of TechnologyTaichung411030TaiwanChina Department of Information Technology Takming University of Science and TechnologyTaipei City11451TaiwanChina

This study mainly uses the concept of the Internet of Things(IoT)to establish a smart house with an indoor,comfortable,environmental,and real-time monitoring *** the smart house,this investigation employed the temperature-and humidity-sensing module and the lightness module to monitor any con-dition for an intelligent-living *** data of temperature,humidity,and lightness are transmitted wirelessly to the human-machine *** correlation of the weight of the extension theory is used to analyze the ideal and comfortable environment so that people in the indoor environment can feel better thermal comfort and *** this study,improved particle swarm optimization(IPSO)is employed—an effective evolutionary method used to search the function *** is simple and has a fast *** convergence accuracy of this algorithm is not high at the beginning,and it can easily fall into the local extreme *** effect of the inertia weight in mix extension theory and PSO becomes IPSO-Extension Neural Network(ENN),which was analyzed and found *** by the idea of power function,a new non-linear strategy for decreasing inertia weight(DIW)was proposed based on the existing linear ***,a novel hierarchical multi-sensor data fusion algorithm adopting this strategy was presented,and the weight factor of the data fusion was *** distinctive feature of this algorithm is its capability of fusing data in a near-optimal manner when there is no available information about the reliability of the information sources,the degree of redundancy/complementarities of the information sources,and the structure of the *** obtained effective information from the fusion data,successfully removed the noise disturbance,and achieved favorable results.

关键词： IoT data fusion extension theory particle swarm optimization decreasing inertia weight IPSO-ENN

Translocator protein 18 kDa(TSPO): old dogma, new mice, new structure, and new questions for neuroprotection

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Neural Regeneration Research 2015年第6期10卷 878-880页

作者： eun-jung Kim Seong-Woon Yu Department of Brain and Cognitive Science Daegu Gyeongbuk Institute of Science and Technology (DGIST)

The normal development and optimal functioning of the brain requires a vigilant immune surveillance system to detect and remove potential risk factors and prevent infection and tissue damage. Microglia are the resident immune cells and the frontline defenders responsible for the immune response of the brain. Resting microglia possess a ramified morphology with numerous thin processes that continuously sample the environment. In response to inflammatory signals, microglia become activated and transform their morphology into a thick, amoeboid-like shape. Activated microglia proliferate, tolerate to sites of iniurv,

关键词： TSPO old dogma Translocator protein 18 kDa new mice new structure

InIncidence and clinical features of endoscopic ulcers developing after gastrectomy

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World Journal of Gastroenterology 2012年第25期18卷 3260-3266页

作者： Woo Chul Chung eun jung Jeon Kang-Moon Lee Chang Nyol Paik sung Hoon jung jung Hwan Oh Ji Hyun Kim Kyong-Hwa Jun Hyung Min Chin Department of Internal Medicine The Catholic University of KoreaSeoul 130-709South Korea Department of Surgery The Catholic University of Korea College of MedicineSeoul 130-709South Korea

AIM： To determine the precise incidence and clinica features of endoscopic ulcers following gastrectomy. METHODS： A consecutive series of patients who un- derwent endoscopic examination following gastrectomy between 2005 and 2010 was retrospectively analyzed. A total of 78 patients with endoscopic ulcers and 759 without ulcers following gastrectomy were enrolled. We analyzed differences in patient age, sex, size of the le- sions, method of operation, indications for gastric resec- tion, and infection rates of Helicobacterpylor/（H. pylor/~ between the nonulcer and ulcer groups. RESULTS： The incidence of endoscopic ulcers after gastrectomy was 9.3% and that of marginal ulcers was 8.6%. Ulcers were more common in patients with Billroth l] anastomosis and pre-existing conditions forpeptic ulcer disease （PUD）. Infection rates of H. pylori- did not differ significantly between the two groups. The patients who underwent operations to treat PUD had lower initial levels of hemoglobin and higher rates of hospital admission. CONCLUSION： H. pylori was not an important factor in ulcerogenesis following gastrectomy. For patients who underwent surgery for PUD, clinical course of mar- ginal ulcers was more severe.

关键词： Gastrectomy Marginal ulcer Helicobacterpylori

Novel predictors for lymph node metastasis in submucosal invasive colorectal carcinoma

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World Journal of Gastroenterology 2017年第32期23卷 5936-5944页

作者： Kwangil Yim Daeyoun David Won In Kyu Lee Seong-Taek Oh eun Sun jung sung Hak Lee Department of Hospital Pathology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of Korea Department of Surgery Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of Korea Department of Surgery Uijeongbu St.Mary’s HospitalCollege of MedicineThe Catholic University of Korea

AIM To evaluate a novel grading system to predict lymph node metastasis(LNM) in patients with submucosal invasive colorectal carcinoma(SICRC).METHODS We analyzed the associations between LNM and various clinicopathological features in 252 patients with SICRC who had undergone radical surgery at the Seoul Saint Mary's hospital between 2000 and *** LNM was observed in 31 patients(12.3%). The depth and width of the submucosal invasion, lymphatic invasion, tumor budding, and the presence of poorly differentiated clusters(PDCs) were significantly associated with the incidence of LNM. Using multivariate analysis, the receiver operating characteristic curvewas calculated and the area under curve(AUC) was used to compare the ability of the different parameters to identify the risk of LNM. The most powerful clinicopathological parameter for predicting LNM was lymphatic invasion(difference AUC = 0.204), followed by the presence or absence of tumor budding(difference AUC = 0.190), presence of PDCs(difference AUC = 0.172) and tumor budding graded by the Ueno method(difference AUC = 0.128). CONCLUSION Our results indicate that the tumor budding and the depth multiplied by the width measurements of submucosal invasion can provide important information for patients with SICRC.

关键词： Colorectal cancer Neoplasm invasion Lymph node Metastasis

Dedifferentiated liposarcoma of the small bowel mesentery presenting as a submucosal mass

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World Journal of Gastrointestinal Oncology 2011年第7期3卷 116-118页

作者： eun-jung Cha Department of Pathology Konyang University HospitalKonyang University School of Medicine

Dedifferentiated liposarcoma(DDLPS) is a variant of liposarcoma but with a more aggressive *** occurs most commonly in the retroperitoneum and rarely in any other anatomical *** describe a case of DDLPS arising from the small bowel mesentery presenting as submucosal mass of the small *** current case is unusual as the tumor originated from the small bowel mesentery and a dedifferentiated component transmurally invaded the small bowel wall,including the small bowel submucosa.

关键词： Dedifferentiated liposarcoma Small bowel mesentery

Induction of vascular endothelial growth factor receptor expression in human umbilical vein endothelial cells after repeated bevacizumab treatment in vitro

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International Journal of Ophthalmology(English edition) 2017年第7期10卷 1064-1068页

作者： Ji eun Lee Jin Young Kim Jae Ho jung Dong Hoon Shin sung Who Park Department of Ophthalmology School of MedicinePusan National University Medical Research Institute Pusan National University Hospital Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan Hospital Department of Pathology School of MedicinePusan National University

AIM： To investigate the mechanism underlying the loss of responsiveness to anti-vascular endothelial growth factor（VEGF） treatment after repeated injections for choroidal neovascularization, VEGF and VEGF receptor（VEGFR） expressions were evaluated following repeated bevacizumab treatments in hypoxic human umbilical vein endothelial cells（HUVECs） in ***： HUVECs were incubated under hypoxic conditions in two media of different bevacizumab concentrations（1.0 or 2.5 mg/m L） for 17 h, and then in a new medium without bevacizumab for 7h. This procedure was repeated twice more. A culture with an identical volume of excipients served as the control. Cytotoxicity and cell proliferation were assessed using 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide and Ki-67 assays, respectively. Levels of VEGF and VEGFR were assessed using enzyme-linked immunosorbent assay and Western blot ***： Cytotoxic effects were not reported for either bevacizumab concentration. Cell proliferation was not reduced after anti-VEGF treatments. VEGF level after single treatment was significantly higher than that of the control and after repeated treatments. Phosphorylated VEGFR-2 expression increased significantly after singleand repeated bevacizumab treatments compared with the control. The 1.0 mg/m L bevacizumab induced significantly higher expressions of VEGFR-2 than the 2.5 mg/m L in single and repeated treatment ***： Bevacizumab treatment of HUVECs elevated VEGFR expression in both single and repeated treatments, indicating a mechanism for the reduced efficacy of anti-VEGF therapy in ocular neovascular disorders.

关键词： vascular endothelial growth factor vascular endothelial growth factor receptor choroidal neovascularization bevacizumab repeated treatments