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Season modulates endocrinological profiles and sex behavioural characteristics in indigenous male goats under tropical humid island ecosystem

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Asian pacific Journal of Reproduction 2022年第4期11卷 183-192页

作者： Perumal Ponraj Jai sunder Arun Kumar De Rafeeque Rahman Alyethodi Purna Chandra Mishra Sneha Bhowmick Debasis Bhattacharya ICAR-Central Island Agricultural Research Institute Port Blair-744105Andaman and Nicobar IslandsIndia Department of ARGO OUAT-College of Veterinary ScienceBhubaneswar-751003OdishaIndia

Objective:To measure the seasonal effect on endocrinological profiles and sex behavioural profiles during rainy and dry summer seasons in male Andaman local goat in Andaman and Nicobar Islands,***:Ten adult male Andaman local goats were selected from the goat breeding farm,ICAR-Central Island Agricultural Research Institute,Port Blair,Andaman and Nicobar Islands,*** profiles such as follicle stimulating hormone(FSH),luteinizing hormone(LH),testosterone,thyroid stimulating hormone(TSH),triiodothyronine(T3),thyroxine(T4),cortisol and prolactin were analysed with enzyme-linked immunosorbent assay *** behavioural profiles such as libido score,mating ability score and sex behavioural score were measured during rainy and dry summer seasons in male Andaman local ***:Endocrinological profiles as well as sex behavioural profiles differed significantly between rainy season and dry summer season(P<0.05).The levels of FSH,LH,testosterone,TSH,T3,and T4 were significantly higher in rainy season than in dry summer season whereas cortisol and prolactin were significantly higher in dry summer season than in rainy season(P<0.05).The ratio of T3:T4 was significantly higher in rainy season than in dry summer ***,libido score,mating ability score and sex behavioural score were significantly higher in rainy season than in dry summer season(P<0.05).Conclusions:Rainy season has significantly higher beneficial effects than summer season on reproduction and artificial breeding programmes in semi-intensive management of goat under the tropical humid island ecosystem in Andaman and Nicobar Islands.

关键词： Andaman and Nicobar Islands Hormone Goat Libido Season Tropical humid island Island ecosystem Rain fall Temperature humidity index Light hour

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An Empirical Analysis of SINO-PAK Bilateral Trade Performance ——Based on the Gravity Model of Trade

An Empirical Analysis of SINO-PAK Bilateral Trade Performanc...

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作者： SHAM sunder 南京理工大学

学位级别：硕士

Pakistan and China enjoy a cordial relationship over the *** decades-long history of friendly relationship in both countries bore the fruits in the form of Pakistan–China free-trade agreement（PCFTA）in 2006 signed in Nov.2006 and effect from July *** primary purpose of the study is to analyses Pakistan’s bilateral trade performance and influence of this Free Trade Agreement（FTA）with China and also its FTA partner nations by implementing gravity model of trade in a balanced panel dataset dealing with the period *** model used for the analysis of data which is a typically used tool for the evaluation of bilateral trade activities and also showed to be useful in describing bilateral trade of Pakistan with China and with all Free Trade Agreement（FTA）-partner countries by higher values of *** outcomes showed that GDP,trade openness in each country,WTO and the shared border nations positively influenced on Pakistan’s bilateral trade with all FTA-partner nations,while distance and inflation showed a negative relation towards trade *** additionally specified that the overall Trade Agreements PTAs impact on bilateral trade of Pakistan along with its FTA-partner nations is strongly significant and *** have also estimated enormous Pakistan’s trade potential just in case of *** Pakistan also can lessen its total trade deficit by deflecting its exports out of traditional or conventional destinations towards China,and it is a market of over millions of *** can be accomplished by boosting private sector of Pakistan to improve its business procedures and policies,spend money on innovative work,enhance human capital,look for international quality accreditations,and furthermore meet quality criteria as anticipated by the *** sectors of Pakistan,as well as exporters,must take on new steps to increase and maximize the exports to China and to generate sensible equality in the bilateral trading relationshi

关键词： Bilateral Trade Gravity Model Free Trade Agreement Panel Data China and Pakistan

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董事激励与公司业绩——实验的证据

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南开管理评论 2004年第4期7卷 4-14页

作者： Anish Shah Shyam sunder 耶鲁大学管理学院卡内基梅隆大学南开大学泽尔腾实验室

我们在实验框架下检验了董事会成员的激励对股东财富和CEO报酬的影响,以及该报酬与公司业绩之间的敏感度.文中提出了两种任命董事的方法,一种由CEO任命,另一种由最大的股东自动担任董事.由董事会决定CEO的报酬,而CEO负责企业的生产、投... 详细信息

我们在实验框架下检验了董事会成员的激励对股东财富和CEO报酬的影响,以及该报酬与公司业绩之间的敏感度.文中提出了两种任命董事的方法,一种由CEO任命,另一种由最大的股东自动担任董事.由董事会决定CEO的报酬,而CEO负责企业的生产、投资和分红决策.投资者根据接收到的每个公司的分红、资本收益这些信息,通过买卖这些企业的股票来调整他们的资产组合.我们发现,薪酬与业绩之间的敏感度随董事持股比例的增加而上升.此外,当大股东作为董事会成员时,经济体所产生的财富(股东财富是其中的一部分)更大;而当CEO选择董事时,结果是缺乏效率的.本文讨论了关于董事职能和相关代理成本这一研究结果,以及标准会计框架下,限制执行人员报酬和报表标准化要求.

关键词： CEO 首席执行官公司业绩独立董事制度激励机制薪酬体系委托-代理关系股东利益最大化

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Holistic Psychopharmacology of Fumaria indica(Fumitory)

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Chinese Medicine 2012年第4期3卷 182-199页

作者： Anshul Shakya Shyam sunder Chatterjee Vikas Kumar Neuropharmacology Research Laboratory Department of Pharmaceutical EngineeringIndian Institute of Technology(Banaras Hindu University)VaranasiIndia Stettiner Straвe 1 KarlsruheGermany

Fumaria indica is a medicinal plant of the fumitory family wildly growing throughout India. Classical texts of Ayurveda, i.e. the oldest traditionally known health care and medical system originating in Indian subcontinent, mentions diverse medicinal uses of the plant. During more recent decades broad spectrums of therapeutically interesting pharmacological properties of its extracts and secondary metabolites have also been reported. Recent observations made during efforts to define its pharmacological activity profile according to the Ayurvedic concepts of mind body medicine have revealed exceptionally broad spectrums of psychopharmacological activity profiles of diverse types of hydro alcoholic extracts of the plant. These effects of the extracts become apparent after their repeated daily doses only. Taken together with prior preclinical knowledge on the plant, these observations strongly suggest that Fumaria indica could be an easily available source for discovering and developing phyto-pharmaceuticals or drugs potentially useful for treatments of mental health problems commonly associated with numerous physical disorders and chronic diseases. Since several psychoactive and other phytochemical of Fumaria indica are also encountered in other plants commonly used in Chinese and other traditionally known medical systems, observations made and the holistic strategy used for defining its psychopharmacological activity profile could be of interest of others involved in efforts necessary for proper understanding of therapeutic potentials of many plants containing Fumaria alkaloids and other bioactive phytochemicals present in Fumaria indica.

关键词： Fumaria indica Fumitory Alkaloids Ayurveda Holistic Psychopharmacology Comorbid Psychopathologies Therapeutic Potential

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右美托咪定给药后引起大鼠心脏MicroRNA差异表达

右美托咪定给药后引起大鼠心脏MicroRNA差异表达

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作者： Shiva sunder Rajchal 昆明医科大学

学位级别：硕士

目的:右美托咪定的应用可能在心脏外科手术中具有有利影响。MicroRNAs是一种有基因表达调控功能的非编码RNA。本研究旨在研究MicroRNAs在右美托咪定心脏保护中的作用。方法:本研究入选了六只大鼠并分成了两组:右美托咪定组和对照组,右... 详细信息

目的:右美托咪定的应用可能在心脏外科手术中具有有利影响。MicroRNAs是一种有基因表达调控功能的非编码RNA。本研究旨在研究MicroRNAs在右美托咪定心脏保护中的作用。方法:本研究入选了六只大鼠并分成了两组:右美托咪定组和对照组,右美托咪定组大鼠腹腔注射右美托咪定(100ug/Kg),对照组大鼠腹腔注射同等剂量的生理盐水。给射后30分钟,麻醉下取出大鼠标记后储存在液氮中。所有样本的microRNAs表达量通过microRNA基因芯片检测。结果:两组大鼠心脏microRNA表达量存在差异,其中5 个microRNA(mo-miRNA-X2,rno-miRNA-X3,rno-miRNA-X4,rno-miRNA-X5 and rno-miRNA-X6)的表达量上调的,1个microRNA的表达量是下调的。对照组和右美托咪定组的大鼠的microRNAs表达量通过T检验进行对比,P小于0.05(P<0.05),这表明上述结果具有统计学意义。结论:右美托咪定可引起心脏microRNA产生差异表达,这些差异表达的microRNA可能与心脏保护有关。

关键词：右美托咪定 microRNAs 心肌缺血再灌注

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Seasonal stress on semen quality profiles, seminal biochemical and oxidative stress attributes in endangered Teressa goat of Andaman and Nicobar Islands

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Asian pacific Journal of Reproduction 2023年第6期12卷 288-298页

作者： P.Perumal Jai sunder A.K.De D.Bhattacharya A.K.Nahak R.Vikram E.B.Chakurkar ICAR-Central Island Agricultural Research Institute Port Blair-744105Andaman and Nicobar IslandsIndia OUAT-College of Veterinary Science and Animal Husbandry Bhubaneswar-751003OdishaIndia ICAR-National Research Centre on Mithun Medziphema-797106NagalandIndia

Objective:To measure seasonal effects on semen quality profiles,seminal biochemical and oxidative stress attributes in fresh and liquid stored semen in monsoon and dry ***:A total of 10 Teressa bucks(3-4 years)were selected from breeding farm,ICAR-Central Island Agricultural Research Institute,Port Blair,Andaman and Nicobar Islands,*** samples(n=25 per season)were collected through artificial vagina method and preserved at refrigerated temperature(5℃)for 48 h using Tris citrate glucose based *** detected semen quality parameters[volume,mass activity,pH,sperm concentration,total motility,viability,total sperm abnormality,and plasma membrane,acrosomal and nuclear integrities],biochemical profiles[aspartate amino transferase(AST),alanine amino transferase(ALT)and total cholesterol],and oxidative stress markers[total antioxidant capacity(TAC)and malondialdehyde(MDA)]during monsoon and dry ***:Semen quality parameters significantly differed between seasons(P<0.05)and among storage periods(P<0.05).Volume,pH,mass activity,motility,viability,acrosomal,plasma membrane and nuclear integrities,and TAC were significantly higher(P<0.05).Sperm concentration,sperm abnormalities,MDA,AST,ALT and total cholesterol were significantly lower in fresh semen of monsoon than dry season(P<0.05).Motility,viability,acrosomal,plasma membrane and nuclear integrities,and TAC were significantly decreased(P<0.05)while sperm abnormality,AST,ALT,total cholesterol and MDA were significantly increased as liquid semen storage period advanced(P<0.05).Conclusions:Monsoon season has higher beneficial effects on semen quality profiles and liquid stored semen remained usable for upto 48 *** quality ejaculates with higher TAC and lower MDA can be cryopreserved and will be used for artificial insemination.

关键词： Andaman and Nicobar Islands Teressa goat Semen quality profiles Season Liquid storage

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Beneficial Effects of <i>Fumaria indica</i>on Chronic Stress-Induced Neurobehavioral and Biochemical Perturbations in Rats

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Chinese Medicine 2012年第1期3卷 49-60页

作者： Gireesh Kumar Singh Geeta Rai Shyam sunder Chatterjee Vikas Kumar Department of Molecular and Human Genetics Faculty of Science Banaras Hindu University Varanasi India Neuropharmacology Research Laboratory Department of Pharmaceutics Institute of Technology Banaras Hindu University Varanasi India Stettiner Str. 1 D-76138 Karlsruhe Germany

Objective: To evaluate the anti-stress activity of standardized extract of Fumaria indica (FI) through validated beha-vioral models of rodents followed by estimation of biochemical changes associated with chronic stress. Methods: Fifty percent ethanolic extract of FI used in this study was standardized on its contents of fumaric acid and its conjugates (0.45% and 0.35% respectively). Stressed Charles Foster rats received unpredictable foot shocks (2 mA, 1 hr, 14 days) through electric grid. FI was given orally as 0.3% carboxymethyl cellulose (CMC) suspension in 100, 200 and 400 mg/kg doses. For comparison, Panax ginseng (PG) extract (100 mg/kg, p.o.) was used as standard adaptogen. Incidence of gastric ulceration, changes in weight of adrenal and spleen, behavioral depression, cognitive dysfunction test and suppression of sexual behavior in male rats were used as validated behavioral models. Plasma corticosterone, brain levels of lipid peroxides (LPO), superoxide dismutase (SOD), catalase (CAT) and reduced glutathione (GSH), and expression of cytokines IL-1β, TNF-α and IL-10 in circulating white blood cells (WBC) were quantified for ascertaining biochemical changes accompanying stress. Results: As compared to vehicle treated stressed rats, the FI and PG treated rats showed fewer incidence of gastric ulceration, reversal of changes in weight of adrenal gland and spleen, reversal of behavioral depression, better performance in passive and active avoidance tests for cognitive function and increased sexual activity. FI and PG significantly decreased chronic unpredictable stress induced elevation of corticosterone, and both extracts normalized also the abnormal oxidative status of the brain observed in stressed rats. FI treatment also suppressed the elevated level of IL-1β, TNF-α and IL-10 in stressed animals. Conclusions: FI could be another adaptogenic herb and fumaric acid and its conjugates are possibly involved in observed bioactivity of its extract.

关键词： Fumaria indica Chronic Stress Corticosterone Anti-Oxidant Cytokines Adaptogen

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Cardioprotective activity of alcoholic extract of Tinospora cordifolia (Willd.) Miers in calcium chloride-induced cardiac arrhythmia in rats

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The Journal of Biomedical Research 2011年第4期25卷 280-286页

作者： Ashish Kumar Sharma Kunal Kishore Divya Sharma B.P Srinivasan Shyam sunder Agarwal Ashok Sharma Santosh Kumar Singh Samir Gaur Vijay Singh Jatav Department of Pharmacology Gyan Vihar School of PharmacySuresh Gyan Vihar UniversityJagatpuraJaipur (Rajasthan)302025India Delhi Institute of Pharmaceutical Sciences & Research Department of PharmacologyPushpviharSector Ⅲ.New Delhi 110017India

The present study investigated the antiarrhythmic activity of alcoholic extract of Tinospora cordifolia （T. cordifolia） in CaCl2 induced arrhythmia. CaCl2 （25 mg/kg） was administered by intravenous infusion （iv） to produce arrhythmia in rats. The animals were then treated with T. cordifolia extract （150, 250, and 450 mg/kg） and verapamil （5 mg/kg,iv）. Lead II electrocardiogram was monitored. Plasma calcium, sodium and potassium levels were measured. In CaCl2 induced arrhythmia, heart rate was decreased by 41.10%, T. cordifolia at 150, 300, and 450 mg/kg decreased the heart rate by 26.30%, 29.16%, and 38.29%, respectively, and verapamil reduced the heart rate by 9.70% compared to the normal group. The PQRST waves were normalized and atrial and ventricular fibrillation was controlled in rats treated with verapamil and T. cordifolia. CaCl2 increased calcium and sodium levels and decreased potassium levels in blood. T. cordifolia dose-dependently decreased calcium and sodium levels and increased potassium levels. Hence, T. cordifolia can be used in antiarrhythmic clinical settings and beneficial in atrial and ventricular fibrillation and flutter and may be indicated in ventricular tachyarrhythmia.

关键词： Tinospora cordifolia arrhythmia cardioprotection.

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结核性巨大肾积水:罕见病例报道(英文)

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中国现代医学杂志 2011年第21期21卷 2686-2688页

作者： sunder Goyal Rajesh Aggarwal Paramjeet Singh Mahesh Gupta Santosh Jha 玛赫西医学研究院印度穆拉纳哈里亚纳邦133203 Deepak医院印度卢迪亚纳133203 玛赫西医学研究院附属医院外科印度穆拉纳哈里亚纳邦133203 泰山医学院附属医院泌尿外科中国山东泰安271000

肾结核是常见疾病并且有不同的表现形式,但是结核引起的巨大肾积水很罕见。多数情况下结核导致实质细胞的萎缩、坏死或钙化,但是这种情况在肾脏一般不明显,除了偶然由结核性输尿管狭窄引起的肾积水病例外。结核性输尿管狭窄呈现巨大肾... 详细信息

肾结核是常见疾病并且有不同的表现形式,但是结核引起的巨大肾积水很罕见。多数情况下结核导致实质细胞的萎缩、坏死或钙化,但是这种情况在肾脏一般不明显,除了偶然由结核性输尿管狭窄引起的肾积水病例外。结核性输尿管狭窄呈现巨大肾积水的情况很少见,因此我们报道了此病例。

关键词：肾脏巨大肾积水结核

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印度企业应对国际金融危机的措施

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时代经贸 2009年第11期7卷 29-32页

作者： sunder Ramaswamy 美国蒙特雷国际问题研究院

从那时开始我们国家开始了一种改革,我们得到了IMF的资助,向香港、新加坡、马来西亚学习。这些改革首先是确确实实放弃过去不合理的政策,工业注重出口,加大与外国的合作,另外减少政府的开销,将私有化与全球化相结合,尽量使各种政策都往... 详细信息

从那时开始我们国家开始了一种改革,我们得到了IMF的资助,向香港、新加坡、马来西亚学习。这些改革首先是确确实实放弃过去不合理的政策,工业注重出口,加大与外国的合作,另外减少政府的开销,将私有化与全球化相结合,尽量使各种政策都往这方面倾斜。到了今天,更多的私营企业都加入了我们的市场,印度原来是卖方市场,现在变成买方市场。原来很高的份额和关税,现在也都降下来了。对于金融市场,过去管控很严格,但现在也逐渐放开。两次的改革保持了印度增长的进度,尤其是在农业和基础建设方面,在减少人民贫困,减少地区差异,深化金融领域的改革,简化政府机构我们都做的比较到位。

关键词：国际金融危机印度企业 WTO

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