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OPTIMUM ORDERING POLICY FOR PREVENTIVE AGE REPLACEMENT

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Journal of Systems Science and Systems Engineering 2009年第3期18卷 283-291页

作者： Young T. park Jing sun Department of Systems Management Engineering Sungkyunkwan University School of Economics and Management Tsinghua University Beijing 100084 China

Most of the spare ordering policies treated up to now have assumed that preventive and corrective replacement costs are equal, which implies in essential that there is no significant need for preventive replacement. This paper presents an ordering policy for preventive age replacement with minimal repair. Introducing the replacement, repair, inventory holding and shortage costs, the expected cost rate is derived. A procedure to determine jointly the ordering time for a spare and the preventive replacement time for the operating unit so as to minimize the expected cost rate is proposed. To explain the ordering policy and the optimization procedure, a numerical example is also included.

关键词： Ordering policy spare age replacement minimal repair

Effective I/O Scheme Based on RTP for Multimedia Communication Systems

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Journal of Computer Science & Technology 2006年第6期21卷 989-996页

作者： Nam-Sup park Chong-sun Hwang Department of Computer Science and Engineering Korea Univcrsity Seoul Korea

The prime standard for audio/video transport in IP networks is the Real-time Transport Protocol （RTP） and it is targeted at useful services for the transport of real-time multimedia data. RTP was originally designed for use in multicast conferences, using the lightweight sessions model. RTP （in particular, the data part） is so tightly coupled to the application that a number of people have developed libraries that implement RTP. However, little is known about the RTP overheads between user area and kernel area within operating systenl. Actually, unnecessary copying between user area and kernel area lowers the system efficiency. In this paper, we present the design and implementation of Enhanced Multimedia Input/Output Scheme based on LINUX. We brought focus to the crossover architecture supporting RTP. Our contributions are able to be summarized into two components： 1） Enhanced Input/Output （EIO） scheme based on LINUX improves the transmission speed by reducing the overheads generated from data copy and context switch between user area and kernel area. And this enables server-based system to transport multimedia data more efficiently. 2） Furthermore, Enhanced Input/Output scheme with RTP （EIORTP） scheme supports efficient multimedia data transmission architecture. The two schemes improve the performance of massive multimedia data transmission.

关键词： kernel area system call EIO RTP EIORTP

Anti-neuro-inflammatory effects of Nardostachys chinensis in lipopolysaccharide-and lipoteichoic acid-stimulated microglial cells

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Chinese Journal of Natural Medicines 2016年第5期14卷 343-353页

作者： sun Young park Young Hun Kim Geuntae park Bio-IT Fusion Technology Research Institute Pusan National University Department of Nanomaterials Engineering Pusan National University

Excessive microglial cell activation is related to the progression of chronic neuro-inflammatory disorders. Heme oxygenase-1(HO-1) expression mediated by the NFE2-related factor(Nrf-2) pathway is a key regulator of neuro-inflammation. Nardostachys chinensis is used as an anti-malarial, anti-nociceptive, and neurotrophic treatment in traditional Asian medicines. In the present study, we examined the effects of an ethyl acetate extract of N. chinensis(EN) on the anti-neuro-inflammatory effects mediated by HO-1 up-regulation in Salmonella lipopolysaccharide(LPS)- or Staphylococcus aureus lipoteichoic acid(LTA)-stimulated BV2 microglial cells. Our results indicated that EN suppressed pro-inflammatory cytokine production and induced HO-1 transcription and translation through Nrf-2/antioxidant response element(ARE) signaling. EN markedly inhibited LPS- and LTA-induced activation of nuclear factor-kappa B(NF-?B) as well as phosphorylation of mitogen-activated protein kinases(MAPKs) and signal transducer and activator of transcription(STAT). Furthermore, EN protected hippocampal HT22 cells from indirect neuronal toxicity mediated by LPS- and LTA-treated microglial cells. These results suggested that EN impairs LPS- and LTA-induced neuro-inflammatory responses in microglial cells and confers protection against indirect neuronal damage to HT22 cells. In conclusion, our findings indicate that EN could be used as a natural anti-neuro-inflammatory and neuroprotective agent.

关键词： Nardostachys chinensis Anti-inflammation Lipopolysaccharide Lipoteichoic acid Heme oxygenase-1

Pullback attractors for the non-autonomous Benjamin-Bona-Mahony equation in unbounded domains

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Science China Mathematics 2011年第4期54卷 741-752页

作者： park Jong Yeoul park sun Hye Department of Mathematics Pusan National University

The existence of a pullback attractor is proven for the non-autonomous Benjamin-Bona-Mahony equation in unbounded *** asymptotic compactness of the solution operator is obtained by the uniform estimates on the tails o... 详细信息

关键词： Benjamin-Bona-Mahony equation pullback attractor unbounded domain

Delivery of nitric oxide-releasing silica nanoparticles for in vivo revascularization and functional recovery after acute peripheral nerve crush injury

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Neural Regeneration Research 2022年第9期17卷 2043-2049页

作者： Jung Il Lee Ji Hun park Yeong-Rim Kim Kihak Gwon Hae Won Hwang Gayoung Jung Joo-Yup Lee Jeong-Yun sun Jong Woong park Jae Ho Shin Myoung-Ryul ok Department of Orthopedic Surgery College of MedicineKorea UniversitySeoulRepublic of Korea Medical Sensor Biomaterial Research Institute Kwangwoon UniversitySeoulRepublic of Korea Center for Biomaterials Korea Institute of Science&TechnologySeoulRepublic of Korea Department of Materials Science and Engineering Seoul National UniversitySeoulRepublic of Korea Department of Orthopedic Surgery College of MedicineCatholic UniversitySeoulRepublic of Korea Department of Chemistry Kwangwoon UniversitySeoulRepublic of Korea

Nitric oxide(NO)has been shown to promote revascularization and nerve regeneration after peripheral nerve ***,in vivo application of NO remains challenging due to the lack of stable carrier materials capable of storing large amounts of NO molecules and releasing them on a clinically meaningful time ***,a silica nanoparticle system capable of reversible NO storage and release at a controlled and sustained rate was *** this study,NO-releasing silica nanoparticles(NO-SNs)were delivered to the peripheral nerves in rats after acute crush injury,mixed with natural hydrogel,to ensure the effective application of NO to the *** using a polymer dye and immunohistochemical staining for the detection of CD34(a marker for revascularization)results showed that NO-releasing silica nanoparticles increased revascularization at the crush site of the sciatic *** sciatic functional index revealed that there was a significant improvement in sciatic nerve function in NO-treated *** and anatomical analyses showed that the number of myelinated axons in the crushed sciatic nerve and wet muscle weight excised from NO-treated rats were ***,muscle function recovery was improved in rats treated with *** together,our results suggest that NO delivered to the injured sciatic nerve triggers enhanced revascularization at the lesion in the early phase after crushing injury,thereby promoting axonal regeneration and improving functional recovery.

关键词： crush injury nerve injury,nerve regeneration nitric oxide peripheral nerve revascularization silica nanoparticles

Guidance on the Choice of Threshold for Binary Forecast Modeling

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Advances in Atmospheric Sciences 2008年第1期25卷 83-88页

作者： Keon Tae SOHN sun Min park Department of Statistics Pusan National University

This paper proposes useful guidance on the choice of threshold for binary forecasts. In weather forecast systems, the probabilistic forecast cannot be used directly when estimated too smoothly. In this case, the binary forecast, whether a meteorological event will occur or not, is preferable to the probabilistic forecast. A threshold is needed to generate a binary forecast, and the guidance in this paper encompasses the use of skill scores for the choice of threshold according to the forecast pattern. The forecast pattern consists of distribution modes of estimated probabilities, occurrence rates of observations, and variation modes. This study is performed via Monte-Carlo simulation, with 48 forecast patterns considered. Estimated probabilities are generated by random variate sampling from five distributions separately. Varying the threshold from 0 to 1, binary forecasts are generated by threshold. For the assessment of binary forecast models, a 2×2 contingency table is used and four skill scores （Heidke skill score, hit rate, true skill statistic, and threat score） are compared for each forecast pattern. As a result, guidance on the choice of skill score to find the optimal threshold is proposed.

关键词： binary forecast Monte-Carlo simulation threshold skill score

A case of rapidly progressing leiomyosarcoma combined with squamous cell carcinoma in the esophagus

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World Journal of Gastroenterology 2013年第32期19卷 5385-5388页

作者： Su sun Jang Woo Tae Kim Bong Suk Ko Eun Hae Kim Jong ok Kim Kuhn park Seung Woo Lee Division of Gastroenterology Department of Internal MedicineDaejeon St. Mary’s HospitalCatholic University of Korea Department of Pathology Catholic University of KoreaDaejeon St. Mary’s Hospital Department of Thoracic and Cardiovascular Surgery Catholic University of KoreaDaejeon St. Mary’s Hospital

Esophageal leiomyosarcoma is a rare tumor that accounts for less than 1%of all malignant esophageal *** leiomyosarcoma combined with squamous cell carcinoma is even rarer than solitary *** experienced a case of leiomy... 详细信息

关键词： Leiomyosarcoma Carcinoma Squamous cell Esophagus Sarcoma

An Efficient Data Dissemination Scheme for Spatial Query Processing

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Journal of Computer Science & Technology 2007年第1期22卷 131-134页

作者： Kwangjin park Hyunseung Choo Chong-sun Hwang School of Information and Communication Engineering Sungkyunkwan University 440-746 Suwon Korea Department of Computer Science and Engineering Korea University 5-1 Anam-Dong Seongbuk-Ku Seoul 136-701 Korea

Due to the personal portable devices and advances in wireless communication technologies, Location Dependent Information Services （LDISs） have received a lot of attention from both the industrial and academic communities. In LDISs, it is important to reduce the query response time, since a late query response may contain out-of-date information. In this paper, we study the issue of LDISs using a Voronoi Diagram. We introduce a new NN search method, called the Exponential Sequence Scheme （ESS）, to support NN query processing in periodic broadcast environment. This paper aims to provide research directions towards minimizing both the access latency and energy consumption for the NN-query processing.

关键词： air index wireless data broadcasting mobile computing

Estimation of plasma density perturbation from dusty plasma injection by laser irradiation on tungsten target in DiPS

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Plasma Science and Technology 2020年第4期22卷 90-96页

作者： In Je KANG Min-Keun BAE In sun park Min Ji LEE Kyu-sun CHUNG Department of Electrical Engineering Hanyang UniversitySeoul 133791Republic of Korea Plasma Technology Research Center National Fusion Research InstituteGunsan 54004Republic of Korea

To investigate the interaction of dusty plasma with magnetized plasmas at divertor plasma simulator,radial profiles of plasma density(ne)and electron temperature were measured in terms of plasma discharge currents and magnetic flux intensity by using a fast scanning probes system with triple *** plasma with dusts(a generation rate of 3μg s-1 and a size of 1–10μm)was produced via interactions between a high-power laser beam and a full tungsten *** ne increases,the scale of the effects of dusty plasma injection on magnetized plasmas was ***,the duration of transient fluctuation was *** numerical estimation of plasma density perturbation due to dusty plasma injection,the result was 10%at a core region of the magnetized plasma with ne of(2–5)×10^11 cm^-3 at steady state condition.

关键词： plasma density perturbation dusty plasma tungsten dust DiPS