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Predicted pro-inflammatory hs-CRP score and non-alcoholic fatty liver disease

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Gastroenterology Report 2023年第1期11卷 462-468页

作者： Akinkunmi Paul Okekunle Jiyoung Youn Sihan Song Goh Eun Chung sun Young Yang Young sun Kim jung Eun Lee Department of Food and Nutrition College of Human EcologySeoul National UniversitySeoulKorea Research Institute of Human Ecology Seoul National UniversitySeoulKorea Healthcare System Gangnam Center Healthcare Research InstituteSeoul National University HospitalSeoulKorea

Background:Non-alcoholic fatty liver disease(NAFLD)is a major contributor to liver diseases globally,yet there are limited studies investigating the impact of diet and lifestyle factors on its *** study aimed to examine the association between the prevalence of NAFLD and predicted pro-inflammatory high-sensitivity C-reactive protein(hs-CRP)***:We included 1,076 Korean adults who underwent a medical examination at the Seoul National University Hospital Gangnam Healthcare Center in Korea between May and December 2011 and updated in *** predicted pro-inflammatory hs-CRP score was derived from pro-inflammatory demographic,lifestyle,dietary,and anthropometric factors,and NAFLD was diagnosed using liver ***-adjusted odds ratios(ORs)and 95%confidence intervals(CIs)of NAFLD odds according to predicted pro-inflammatory hs-CRP score were estimated using logistic regression at a two-sided P<***:Among the 1,076 participants,320 had *** multivariable-adjusted ORs and 95%CIs for NAFLD by tertiles of predicted pro-inflammatory hs-CRP score were 1.00,3.30(2.06,5.30),18.25(10.47,31.81;P<0.0001)in men and women combined,1.00,1.77(1.10,2.84),and 3.26(2.02,5.28;P<0.0001)among men only,and 1.00,3.03(1.39,6.62),and 16.71(7.05,39.63;P<0.0001)among women ***:Predicted pro-inflammatory hs-CRP score was associated with higher odds of *** dietary and lifestyle changes related to lower inflammation might be a valuable strategy for preventing NAFLD.

关键词： non-alcoholic fatty liver disease fatty liver high-sensitivity C-reactive protein pro-inflammation

Study on the Long Term Sensing Properties of pCO_2 Sensitive Electrode

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稀有金属材料与工程 2006年第A3期35卷 217-220页

作者： Szu-Ping Chen jung-Chuan Chou Tai-Ping sun Shen-Kan Hsiung Institute of Electronic Engineering Chung Yuan Christian University Chung-Li Taiwan 320 China Graduate School of Electronic Engineering National Yunlin University of Science and Technology Douliou Taiwan 640 China Department of Electrical Engineering National Chi Nan University Nantou Taiwan 545 China

In this paper,the pCO_2 sensitive electrode was studied for continuous *** solid electrolyte membrane and gas-permeable membrane were coated on the surface of the pH sensitive electrode which was fabricated based on the SnO_2/ITO glass *** to the experimental results,the pCO_2 sensitive electrode shows the sensitivity of about 35 mV/decade in detection range between 0.1 mmol/L and 50 mmol/***,the investigated sensing structure exhibits the convenient and pragmatic properties of the pCO_2 *** summary,the advantages of the pCO_2 sensitive electrode are low-cost and disposable based on the separative structure.

关键词： pCO2 sensitive electrode solid electrolyte membrane gas-permeable membrane SnO2/ITO glass substrate

Application of Sodium Ion Sensor Based on the SnO_2/ITO Glass in the Detection of Rinsing Solution for Contact Lenses

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稀有金属材料与工程 2006年第A3期35卷 240-241页

作者： Jui-Fu Cheng jung-Chuan Chou Tai-Ping sun Shen-Kan Hsiung Institute of Electronic Engineering Chung Yuan Christian University Chung-Li Taiwan 320 China Graduate School of Electronic Engineering National Yunlin University of Science and Technology Douliou Taiwan 640 China Institute of Electrical Engineering National Chi Nan University Nantou Taiwan 545 China

This paper presents the studying results of the sodium ion sensor device based on the SnO_2/ITO glass structure in the detection of rinsing solution for contact *** selective membrane contains poly (vinyl chloride) (PVC),bis (2-ethylhexyl) sebacate (DOS),(12-crown-4) methylmalonate (B12C4),and sodium tetrakis (4-fluoropbenyl) borate dehydrate (NaTFBD). The final weight ratios are PVC:DOS:B12C4:NaTFBD=33:66:2:*** this condition,the sensor has performances with linear sensitivity,short response time,good repeatability and *** sensor was used to measure the rinsing solution for the contact *** the experimental results show close to the accurate value for four commercial products,this sensor can preliminary be used in detecting the rinsing solution for the contact *** this structure and sodium-sensing membrane to construct the sodium sensor is proven successfully in this application.

关键词： sodium ion sensor solution for contact lenses tin oxide electrode B12C4

Potentiometric Urea Biosensor Based on Ion-Selective Electrode by Different Immobilization Procedures

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稀有金属材料与工程 2006年第A3期35卷 309-312页

作者： Nien-Hsuan Chou jung-Chuan Chou Tai-Ping sun Shen-Kan Hsiung Institute of Electronic Engineering Chung Yuan Christian University Chung-Li Taiwan 320 China Graduate School of Electronic Engineering National Yunlin University of Science and Technology Douliou Taiwan 640 China Department of Electrical Engineering National Chi Nan University Nantou Taiwan 545 China

Enzyme was immobilized on an ammonium ion-selective electrode by different *** ion-selective electrode is not completely ion-specific,and interfering ions react with the ion-selective electrode membrane,altering the measured ***,the characteristics of the effect of other ions on ammonium ion-selective electrode-based urea biosensors are *** on the experimental results,the urea biosensor based on entrapment had a high response voltage of around 189 mV and fast response time of around 16 ***,selectivity of the urea biosensor in different interfering ions was considered to elucidate the characteristics of ammonium ion-selective electrode-based biosensors.

关键词： enzyme immobilization ammonium ion-selective electrode interfering ions urea biosensors selectivity

Devastating complication of negative pressure wound therapy after deep inferior epigastric perforator free flap surgery:A case report

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World Journal of Clinical Cases 2023年第1期11卷 143-149页

作者： SooA Lim Dong Yun Lee BumSik Kim jung Soo yoon Yea Sik Han SuRak Eo Department of Plastic and Reconstructive Surgery DongGuk University Medical CenterGoYang 10326South Korea

BACKGROUND Thermal injuries on free transferred or replanted tissues resulting from loss of sensibility are an infrequent *** require immediate and appropriate management before they progress to an irreversible *** negative pressure wound therapy(NPWT)can prevent wound progression by increasing microcirculation,the inappropriate application of NPWT on complicationthreatened transferred and replanted tissues can induce an adverse *** SUMMARY A 48-year-old woman who underwent immediate breast reconstruction with a deep inferior epigastric artery perforator free *** applying a heating pad directly to the flap site,she sustained a deep second to third-degree contact burn over 30%of the transferred flap on postoperative 7 *** the necrotic changes had progressed,we applied an NPWT dressing over the burned area after en-bloc debridement of the transferred tissues on postoperative 21 *** 4 d of NPWT application,the exposed fatty tissues of the flap changed to dry and browncolored necrotic *** further debridement,we noted that the wound gradually reached total necrosis with a collapsed vascular pedicle of deep inferior epigastric *** Although NPWT has been shown to be successful for treating various wound types,the significant risk of NPWT application in short-lasting reconstructed flap wounds after thermal injury should be reminded.

关键词： Negative Pressure Wound Therapy Complications Breast reconstruction Deep inferior epigastric artery perforator Free flap Burn injury Case report

Predicting Bitcoin Trends Through Machine Learning Using Sentiment Analysis with Technical Indicators

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Computer Systems Science & Engineering 2023年第8期46卷 2231-2246页

作者： Hae sun jung Seon Hong Lee Haein Lee Jang Hyun Kim Department of Applied Artificial Intelligence/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea Department of Interaction Science/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea

Predicting Bitcoin price trends is necessary because they represent the overall trend of the cryptocurrency *** the history of the Bitcoin market is short and price volatility is high,studies have been conducted on the factors affecting changes in Bitcoin *** have been conducted to predict Bitcoin prices using Twitter ***,the amount of data was limited,and prices were predicted for only a short period(less than two years).In this study,data from Reddit and LexisNexis,covering a period of more than four years,were *** data were utilized to estimate and compare the performance of the six machine learning techniques by adding technical and sentiment indicators to the price data along with the volume of *** accuracy of 90.57%and an area under the receiver operating characteristic curve value(AUC)of 97.48%were obtained using the extreme gradient boosting(XGBoost).It was shown that the use of both sentiment index using valence aware dictionary and sentiment reasoner(VADER)and 11 technical indicators utilizing moving average,relative strength index(RSI),stochastic oscillators in predicting Bitcoin price trends can produce significant ***,the input features used in the paper can be applied on Bitcoin price ***,this approach allows investors to make better decisions regarding Bitcoin-related investments.

关键词： Bitcoin cryptocurrency sentiment analysis price trends prediction natural language processing machine learning

Study on the Drift Calibration Method and Device for the Tin Oxide pH Electrode

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稀有金属材料与工程 2006年第A3期35卷 210-212页

作者： Chu-Neng Tsai jung-Chuan Chou Tai-Ping sun Shen-Kan Hsiung Institute of Electronic Engineering Chung Yuan Christian University Chung-Li Taiwan 320 China Graduate School of Electronic Engineering National Yunlin University of Science and Technology Douliou Taiwan 640 China Department of Electrical Engineering National Chi Nan University Nantou Taiwan 545 China

Drift phenomenon has been known as the drawback of sensors and causes inaccuracy on the long-term measurement. In general,there are two methods to reduce the drift *** is to tune the parameters of the fabrication process to improve the properties of the front-ended *** is to compensate the drift phenomenon by adding extra drift compensation circuit or software in the back-ended readout *** this study,a drift calibration method for the potentiometric sensor was presented and the drift calibration method was performed by using the *** to experimental results,the drift phenomenon of the SnO_2 pH electrode was reduced by the drift calibration device.

关键词： drift phenomenon long-term measurement drift calibration method drift calibration device SnO2 pH electrode

Hybrid integration of 2D materials for on-chip nonlinear photonics

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Light(Advanced Manufacturing) 2023年第3期4卷 311-333页

作者： Vincent Pelgrin Hoon Hahn yoon Eric Cassan Zhipei sun QTF Centre of Excellence Department of Electronics and NanoengineeringAalto UniversityP.O.Box 13500FI-00076 AaltoFinland UniversitéParis-Saclay CNRSCentre de Nanosciences et de Nanotechnologies91120PalaiseauFrance

Interests surrounding the development of on-chip nonlinear optical devices have been consistently growing in the past decades due to the tremendous applications,such as quantum photonics,all-optical communications,optical computing,on-chip metrology,and *** efficient on-chip nonlinear optical devices to meet the requirements of those applications brings the need for new directions to improve the existing photonic *** research has directed the field of on-chip nonlinear optics toward the hybrid integration of two-dimensional layered materials(such as graphene,transition metal dichalcogenides,and black phosphorous)with various integrated *** combination of well-known photonic chip design platforms(e.g.,silicon,silicon nitride)and different two-dimensional layered materials has opened the road for more versatile and efficient structures and devices,which has the great potential to unlock numerous new *** review discusses the modeling and characterization of different hybrid photonic integration structures with two-dimensional materials,highlights the current state of the art examples,and presents an outlook for future prospects.

关键词： Integrated photonics 2D materials Nanophotonic Nonlinear optics Quantum computation All-optical computing Spectroscopy Broadband light sources

The effects of anti-vascular endothelial growth factor agents on human retinal pigment epithelial cells under high glucose conditions

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International Journal of Ophthalmology(English edition) 2017年第2期10卷 203-210页

作者： Jong Rok Oh jung Woo Han yoon Kyung Kim Young-Hoon Ohn Tae Kwann Park Department of Ophthalmology Soonchunhyang UniversityCollege of MedicineSoonchunhyang University Bucheon HospitalBucheonKorea

AIM： To investigate the effects of high glucose levels and anti-vascular endothelial growth factor（VEGF） agents（bevacizumab,ranibizumab and aflibercept） on retinal pigment epithelium（RPE） ***： ARPE-19 cells were cultured at different glucose levels（5.5 mmol/L,25 mmol/L,and 75 mmol/L）.Cell viability was evaluated by MTT assay at 3d after treatment with *** migration ability was measured by wound healing assay at 3d.A cell death detection kit was used to assess apoptosis at 3 and 14 *** proliferation was assessed by EdU assay at *** culture medium was treated with anti-VEGF agents at clinically relevant *** experiment was then repeated at a different glucose ***： The viability and migration of ARPE-19 cells were significantly decreased in the presence of 75 mmol/L as compared to 5.5 mmol/L *** percentage of TUNEL-positive cells was significantly increased and the proliferative potential was decreased with 75 mmol/L compared to 5.5 mmol/L *** were no significant differences in the results between 25 mmol/L and 5.5 mmol/L *** the presence of 75 mmol/L glucose,the groups treated with anti-VEGF showed decreased cell viability and proliferation and increased ***,there were no significant differences between the anti-VEGF ***： High glucose level decreases the viability,wound healing ability,and proliferation of RPE cells,while increasing ***,anti-VEGF agents interfered with the physiological functions of RPE cells under high-glucose conditions,accompanied by decreases in cell viability and proliferation.

关键词： retinal pigment epithelium anti-vascularendothelial growth factor high glucose