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4~6岁电声双模式助听儿童情感韵律识别能力研究

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中华耳科学杂志 2024年第3期22卷 411-414页

作者：刘晓明孙颖金星 KIM Hakyung 刘建菊北京联合大学特殊教育学院北京100075 北京教育科学研究院上海中医药大学康复医学院上海市中医药研究院康复医学研究所华东师范大学康复科学系

目的通过对4~6岁电声双模式助听儿童的高兴、中性及难过3种情感韵律进行研究,探讨不同听觉年龄电声双模式助听儿童的韵律识别能力。方法选取2022年9月至2023年12月某幼儿园就读的生理年龄4~6岁,听觉年龄1~4岁的电声双模式助听儿童32例... 详细信息

目的通过对4~6岁电声双模式助听儿童的高兴、中性及难过3种情感韵律进行研究,探讨不同听觉年龄电声双模式助听儿童的韵律识别能力。方法选取2022年9月至2023年12月某幼儿园就读的生理年龄4~6岁,听觉年龄1~4岁的电声双模式助听儿童32例,按照听觉年龄分为1.5岁组4例、2岁组6例、2.5岁组6例、3岁组6例、3.5岁组4例及4岁组6例。采用华东师范大学康复科学系自制的15个日常用句,分别用高兴、中性和难过3种不同的情感语气读出,让电声双模式助听儿童识别,共45句。分析不同听觉年龄对高兴、难过和中性3种情感韵律的识别能力。结果 1.5岁组、2岁组、2.5岁组、3岁组、3.5岁组及4岁组的情感韵律识别能力得分比较,差异无统计学意义(F=1.246,P>0.05)。6组3种不同类型情感韵律识别能力比较,差异无统计学意义(F=1.174,P>0.05),情感韵律类型和听觉年龄组之间无交互作用,差异无统计学意义(F=0.980,P>0.05)。6组不同听觉年龄情感韵律识别的正确率比较,差异有统计学意义(F=4.106,P<0.01)。结论听觉年龄1~4岁的大龄电声双模式助听儿童,情感韵律识别能力随听觉年龄的增长而升高;但不同听觉年龄对高兴、难过和中性3种情感韵律的识别不存在差异。随着听觉年龄的增长,要重视大龄电声双模式助听儿童情感韵律识别能力的训练。

关键词：听障儿童双模式助听韵律识别人工耳蜗植入儿童

An Efficient Data Dissemination Scheme for Spatial Query Processing

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Journal of Computer Science & Technology 2007年第1期22卷 131-134页

作者： Kwangjin Park Hyunseung Choo Chong-sun hwang School of Information and Communication Engineering Sungkyunkwan University 440-746 Suwon Korea Department of Computer Science and Engineering Korea University 5-1 Anam-Dong Seongbuk-Ku Seoul 136-701 Korea

Due to the personal portable devices and advances in wireless communication technologies, Location Dependent Information Services （LDISs） have received a lot of attention from both the industrial and academic communities. In LDISs, it is important to reduce the query response time, since a late query response may contain out-of-date information. In this paper, we study the issue of LDISs using a Voronoi Diagram. We introduce a new NN search method, called the Exponential Sequence Scheme （ESS）, to support NN query processing in periodic broadcast environment. This paper aims to provide research directions towards minimizing both the access latency and energy consumption for the NN-query processing.

关键词： air index wireless data broadcasting mobile computing

Antioxidant and anti-inflammatory activities of Orostachys japonicus

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Asian Pacific Journal of Tropical Biomedicine 2020年第11期10卷 516-522页

作者： Eun-sun hwang Nhuan Do Thi School of Wellness Industry Convergence Food&NutritionHankyong National University327 Chungang-roAnseong-siGyeonggi-do 17579Korea

Objective: To determine the bioactive compounds of Orostachys japonicus(O. japonicus)(Maxim.) A. Berger extraction by different solvents(70% ethanol or water) and to evaluate the in vitro antioxidant and anti-inflammatory activities. Methods: Total polyphenol, flavonoid, and anthocyanin contents in O. japonicus extract were measured. Antioxidant activities were determined by DPPH, ABTS, and superoxide radical-scavenging ability assays. Anti-inflammatory activities were evaluated by nitric oxide production, tumor necrosis factor-α, and interleukin-6 expression techniques. Results: Extraction with 70% ethanol yielded the highest total polyphenol(60.03 mg/g dry weight) and flavonoid(55.50 mg/g dry weight) contents. The total anthocyanin contents in 70% ethanol and water extracts were 57.25 and 91.71 mg/g dry weight, respectively. The 70% ethanol extract also showed stronger antioxidant activity than the water extract. Antioxidant activity and reducing power increased with the increasing concentration of O. japonicus extract. O. japonicus extract at 0-400 μg/m L did not affect the growth of RAW 264.7 cells, whereas dose-dependent inhibition of nitric oxide, tumor necrosis factor-α, and interleukin-6 production was ***: O. japonicus inhibits oxidative and inflammatory reactions with potentially positive health-related effects.

关键词： Antioxidant inflammatory oxidative

Broadcast-Based Spatial Queries

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Journal of Computer Science & Technology 2005年第6期20卷 811-821页

作者： Kwang-Jin Park Moon-Bae Song Chong-sun hwang Department of Computer Science and Engineering Korea University 5-1 Anam-Dong Seongbuk-Ku Seoul 136-701 Korea

Indexing techniques have been developed for wireless data broadcast environments, in order to conserve the scarce power resources of the mobile clients. However, the use of interleaved index segments in a broadcast cycle increases the average access latency for the clients. In this paper, the broadcast-based spatial query processing methods （BBS） are presented for the location-based services. In the BBS, broadcasted data objects are sorted sequentially based on their locations, and the server broadcasts the location dependent data along with an index segment. Then, a sequential prefetehing and caching scheme is designed to reduce the query response time. The performance of this scheme is investigated in relation to various environmental variables, such as the distributions of the data objects, the average speed of the clients and the size of the service area.

关键词： broadcasting location-aware caching prefetching mobile computing

K2Ti6O13 Nanoparticle-Loaded Porous rGO Crumples for Supercapacitors

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Nano-Micro Letters 2020年第1期12卷 115-123页

作者： Chongmin Lee sun kyung Kim Hankwon Chang Hee Dong Jang Department of Nanomaterials Science and Engineering University of Science and TechnologyYuseong‑guDaejeon 34113Republic of Korea Resources Utilization Research Center Korea Institute of Geoscience and Mineral ResourcesYuseong‑guDaejeon 34132Republic of Korea

One-dimensional alkali metal titanates containing potassium,sodium,and lithium are of great concern owing to their high ion mobility and high specific surface *** those titanates are combined with conductive materials such as graphene,carbon nanotube,and carbon nanofiber,they are able to be employed as efficient electrode materials for *** hexa-titanate(K2Ti6O13,KTO),in particular,has shown superior electrochemical properties compared to other alkali metal titanates because of their large lattice parameters induced by the large radius of potassium ***,we present porous rGO crumples(PGC)decorated with KTO nanoparticles(NPs)for application to *** KTO NP/PGC composites were synthesized by aerosol spray pyrolysis and post-heat *** NPs less than 10 nm in diameter were loaded onto PGCs ranging from 3 to 5μ*** porous structure of the composites was obtained by the activation of rGO by adding an excessive amount of KOH to the *** KTO NP/PGC composite electrodes fabricated at the GO/KOH/TiO2 ratio of 1:3:0.25 showed the highest performance(275 F g−1)in capacitance with different KOH concentrations and cycling stability(83%)after 2000 cycles at a current density of 1 A g−1.

关键词： Potassium hexa-titanate Porous graphene crumples Supercapacitors

Stability of neodymium:YAG laser posterior capsulotomy in eyes with capsular tension rings

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International Journal of Ophthalmology(English edition) 2023年第6期16卷 891-896页

作者： Yang kyung Cho Min sun Kim Department of Ophthalmology St.Vincent’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul 06591Republic of Korea

·AIM: To evaluate the stability of neodymium(Nd):YAG laser posterior capsulotomy in eyes with capsular tension rings(CTRs).·METHODS: A total of 60 eyes that underwent cataract surgery and laser posterior capsulotomy postoperatively were included in this retrospective cohort study. To evaluate the safety and stability of capsulotomy, changes in the size of posterior capsulotomy and anterior chamber depth(ACD) in three groups: the group without CTR, the group with 12 mm CTRs, and the group with 13 mm CTRs, at 1wk, 3, 12, and 15mo after capsulotomy, were compared. ·RESULTS: In the group without CTR and the group with 12 mm CTR, there was no significant change in ACD at every post-laser follow-up. In the group with 13 mm CTR, the ACD change was significant until 3mo after capsulotomy. In all groups, there was a significant increase in the area of capsulotomy between 1wk and 3mo post-laser. Between 3 and 12mo post-laser, only the group with 13 mm CTR showed a significant increase in the area of capsulotomy(P<0.01). ·CONCLUSION: Laser posterior capsulotomy is safe in all three groups. The capsulotomy and ACD become stabilized and have not shown significant changes since 1y postlaser, even with larger CTRs. The maintenance of centrifugal capsular tension can last longer with larger CTRs, and the stability of the capsulotomy site can be reached about 12mo after capsulotomy in pseudophakic eyes with larger CTRs.

关键词： Nd:YAG laser capsulotomy capsular tension ring

Anti-cancer and anti-inflammatory activities of aronia (Aronia melanocarpa) leaves

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Asian Pacific Journal of Tropical Biomedicine 2018年第12期8卷 586-592页

作者： Nhuan Do Thi Eun-sun hwang Department of Nutrition and Culinary Science Hankyong National University

Objective: To determine the anti-cancer effect of aronia leaf extract on SK-Hep1 cells using migration, metallo metrix proteinase-2/-9(MMP-2/-9) and MT-1 MMP expression and to evaluate the anti-inflammatory activities of the leaf extract. Methods: The effect of aronia leaf extract on cancer prevention was investigated. SK-Hep1 human liver cancer cell line was treated with aronia leaf extract at various concentractions. MTT assay was used to measure cancer cell growth inhibition, and wound migration assay was used for metastasis determination. The expression of MMP-2/-9 was measured at the protein level using zymography and the expression of MMP-2/-9 and MT-1 MMP was examined at the gene level by RT-PCR. Raw 264.7 macrophage cells were stimulated with lipopolysaccharides to induce inflammation, and then the inhibition of inflammation was evaluated by treatment of aronia leaf extract. Expressions of interleukin-6, tumor factor-d. Results: SK-Hep1 cell growth was inhibited毩, and nitric oxide(NO) were also determine in proportion to the concentration of aronia leaf extract. In migration assay, aronia leaf extract showed 61.3%-96.3% wound size inhibtion after treating 50-200 μg/mL of aronia leaf extract for 24 h. At the protein level, the expression of MMP-2 and MMP-9 decreased as the concentration of aronia leaf extract treated with SK-Hep1 cells increased. In addition, the same pattern as in the protein was also observed in the mRNA levels. The expressions of MMP-2 and MMP-9 protein were inhibited by 92.2% and 53.8%, respectively after treatment with 200 μg/mL aronia leaf extract. In addition, Raw 264.7 cells treated with aronia leaf extract did not affect cell survival. There was dose dependent inhibition of interleukine-6, tumor necrosis factor-a and nitric oxide after treating aronia leaf extract in lipopolysaccharides-treated Raw cell. Conclusions: The results show that aronia leaf has anticancer and and antimetastatic properties in SK-Hep1 and Raw 264.7 cells.

关键词： Aronia leaf Cancer Metatasis Lipopolysaccharides-induced Inflammation

Development of acquired non-accommodative esotropia in a patient without a trochlear nerve

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International Journal of Ophthalmology(English edition) 2022年第6期15卷 1030-1031页

作者： Hee kyung Yang Jae Hyoung Kim Jeong-Min hwang Department of Ophthalmology Seoul National University College of MedicineSeoul National University Bundang HospitalSeongnam 13620Republic of Korea Department of Radiology Seoul National University College of MedicineSeoul National University Bundang HospitalSeongnam 13620Republic of Korea

Dear Editor,Congenital cranial dysinnervation disorders(CCDD) are neurodevelopmental diseases of the brainstem and cranial nerves;. Congenital superior oblique palsy(SOP) is one of the most representative CCDDs becaus... 详细信息

关键词： nerves diseases oblique

Electrochemically metal-doped reduced graphene oxide films:Properties and applications

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Journal of Materials Science & Technology 2020年第5期40卷 72-80页

作者： Myung-Sic Chae Tae Ho Lee kyung Rock Son Tae Hoon Park Kyo Seon hwang Tae Geun Kim School of Electrical Engineering Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841South Korea Department of Clinical Pharmacology and Therapeutics College of MedicineKyung Hee UniversitySeoul 02447South Korea

The fine control of doping levels in graphene materials such as reduced graphene oxide(RGO)is important to properly manipulate their ambipolar transport characteristics for various device ***,conventional doping methods involve complex chemical reactions,large-scale doping processes,and poor ***,a simple and controllable electrochemical doping treatment(EDT),performed via the conductive channels created at the RGO surface by the application of an electric field,is introduced to tailor the electrical properties of RGO films.X-ray photoelectron spectroscopy and Raman spectroscopy measurements are performed to detect the presence of Ni atoms in RGO films after the EDT(EDT-RGO).Then,EDT-RGO field-effect transistors(FETs)are fabricated with different doping areas(0 to 100%fractional area)on the RGO active channel to investigate the effect and selective-area doping capability of the *** to p-type doping compensation by the intercalated Ni atoms,the electron mobility of the EDT-RGO FET decreases from 1.40 to 0.12 cm2 V-1s-1 compared with that of the undoped RGO-FET,leading to the conversion from ambipolar to unipolar p-type transfer characteristics.

关键词： Reduced graphene oxide Electrochemical doping treatment Electrical breakdown process Field-effect transistor