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Asian Pacific Journal of Tropical Medicine 2011年第9期4卷 673-679页

作者： sumitra chanda Yogesh Baravalia Mital Kaneria Phytochemical Pharmacological and Microbiological LaboratoryDepartment of BiosciencesSaurashtra UniversityRajkot-360 005GujaratIndia

Objective:To explore antiulcer and antimicrobial properties of methanolic extract of Polyalthia longifolia ***:Gastroprotective potential of Polyalthia longifolia was studied on ethanol and ethanol/HCl induced ulcers at 2 different doses(270 and 540 mg/kg/body weight). Antimicrobial efficacy of Polyalthia longifolia(25 mg/mL) was also studied against six gram positive,seven gram negative bacteria and five fungi by agar well diffusion *** inhibitory concentration was determined by agar well diffusion method in two fold serial dilution, in the range of 97-25 000μg/***:The reduction of ulcer index in Polyalthia longifolia treated animals was found to be statistically significant with respect to control *** Polyalthia longifolia exhibited ulcer protection activity in dose dependent manner and was also better than the *** antimicrobial activity,gram positive bacteria were more susceptible to Polyalthia longifolia than gram negative bacteria and fungal ***:Results obtained confirm the antiulcer and antimicrobial potential of the Polyalthia longifolia.

关键词： Polyalthia longifolia Antimicrobial activity Antiulcer activity Ulcer index Methanol extract

Hepatoprotective effect of Woodfordia fruticosa Kurz flowers on diclofenac sodium induced liver toxicity in rats

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Asian Pacific Journal of Tropical Medicine 2011年第5期4卷 342-346页

作者： Yogesh Baravalia Yogeshkumar Vaghasiya sumitra chanda Phytochemical Pharmacological and Microbiological LaboratoryDepartment of BiosciencesSaurashtra UniversityRajkot-360 005GujaratIndia

Objective:To evaluate the protective effect of Woodfordia fruticosa Kurz flowers against experimentally induced liver toxicity in ***:Two different doses of methanol extract of Woodfordia fruticosa(WFM) were evaluated for the hepatoprotective activity against diclofenac sodium induced hepatotoxicity in *** biochemical parameters like alanine aminotransferase(ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP),total protein(TP),albumin(ALB),blood urea nitrogen(BUN) from serum;total protein(TP),glutathione (GSH) levels,catalase(CAT) and glutathione peroxidase(GPx) activities from liver were studied; histopathologic changes of liver were also ***:WFM effectively reduced the elevated levels of serum ALT,AST,ALP and BUN,enhanced the reduced TP,ALB and hepatic GSH,CAT,GPx *** histopathological analysis suggested that WFM decreased the degree of liver fibrosis induced by ***:This study demonstrates the hepatoprotective activity of WFM and thus scientifically support the use of this plant in traditional medicine for the treatment of liver disorders.

关键词： Woodfordia fruticosa Diclofenac Hepatoprotective Biochemical analysis Histopathology

Assessment of effect of hydroalcoholic and decoction methods on extraction of antioxidants from selected Indian medicinal plants

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Asian Pacific Journal of Tropical Biomedicine 2012年第3期2卷 195-202页

作者： Mital Kaneria Bhavana Kanani sumitra chanda Phytochemical Pharmacological and Microbiological LaboratoryDepartment of BiosciencesSaurashtra University

Objective:To assess the effects of extraction methods on antioxidant activities of selected Indian medicinal ***:Different parts of plants were extracted by hydroalcoholic and decoction methods using water and various concentrations of methanol(ME) viz.75%, 50%and 25%*** antioxidant activity of all the different extracts was evaluated using two different antioxidant assays viz.2,2-diphenyl-1-picryl hydrazyl(DPPH) free radical scavenging assay and superoxide anion radical scavenging *** phenol and flavonoid content was also ***:The results showed that the extracting solvent significantly altered the antioxidant property estimations of screened *** correlations between phenolic compositions and antioxidant activities of extracts were *** levels of antioxidant activities were detected in Manilkara zapota(***) as compared with other screened plants. Conclusions:The results obtained appear to confirm the effect of different methods on extraction of antioxidants and antioxidant property of ***.

关键词： Antioxidant Hydroalcoholic extraction Total phenol content DPPH Superoxide Manilkara zapota

Antimicrobial Activity of Polyalthia longifolia (Sonn.) Thw. var. Pendula Leaf Extracts Against 91 Clinically Important Pathogenic Microbial Strains

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Chinese Medicine 2010年第2期1卷 31-38页

作者： sumitra chanda Rathish Nair 不详

The methanol, acetone and 1,4-dioxan fractions of leaves of Polyalthia longifolia (Sonn.) Thw. were evaluated for antibacterial and antifungal activity. 91 clinically important strains were used for the study which were both clinical isolates as well as identified strains. Piperacillin and gentamicin were used as standards for antibacterial assay, while nystatin and flucanazole were used as standards for antifungal assay. The antibacterial activity was more pronounced against gram positive bacterial and fungal strains. Poor activity was shown against gram negative bacterial strains studied.

关键词： Antibacterial Antifungal Polyalthia longifolia Clinical Isolates Organic Solvent Extracts

Antimicrobial Activity of <i>Terminalia catappa</i>L. Leaf Extracts against Some Clinically Important Pathogenic Microbial Strains

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Chinese Medicine 2011年第4期2卷 171-177页

作者： sumitra chanda Kalpna Rakholiya Rathish Nair 不详

Objective: The present study was undertaken to evaluate in-vitro antimicrobial activity of methanol, acetone and N, N-dimethylformamide extracts from leaf of Terminalia catappa L. (Combretaceae). Methods: In vitro antimicrobial activity of all the extracts was done by agar disc diffusion assay. 91 clinically important strains were used for the study, which were both clinical isolates as well as identified strains. Piperacillin and gentamicin were used as standards for antibacterial assay, while nystatin and flucanazole were used as standards for antifungal assay. Antimicrobial activity was determined by measurement of inhibition zone around each paper disc. For each extract three replicate trials were conducted against each organism. Results: The antibacterial activity was more pronounced against bacteria than fungal strains. The Gram positive bacteria were more susceptible than Gram negative bacteria. The methanol extract showed best antibacterial activity. T. catappa leaf extracts showed better antibacterial activity than commercially used antibiotics. Conclusion: Demonstration of antimicrobial activity of T. catappa provides the scientific basis for the use of this plant in the traditional treatment of diseases and may help to discover new chemical classes of antibiotic substances that could serve as selective agents for infectious disease chemotherapy and control. This investigation has opened up the possibility of the use of this plant in drug development for human consumption possibly for the treatment of various infections caused by microbes.

关键词： Terminalia catappa Antibacterial Activity Antifungal Activity Clinical Strains Organic Solvents

Antioxidant and antimicrobial activity of a mangrove plant Avicennia marina(Forsk.)

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Journal of Coastal Life Medicine 2015年第9期 713-717页

作者： Pooja Moteriya Ashish Dalsaniya sumitra chanda Phytochemical Pharmacological and Microbiological LaboratoryDepartment of BiosciencesSaurashtra UniversityRajkot 360005GujaratIndia

Objective:To evaluate the antioxidant and antimicrobial potential of different parts(leaf,stem and pneumatophore)of a mangrove plant Avicennia marina(Forsk.)Vierh(Avicenniaceae).Methods:The extraction was done by cold percolation method using solvents of hexane,ethyl acetate,acetone,methanol and *** phenol and flavonoid content were measured by Folin-Ciocalteu’s reagent and aluminium chloride colorimetric method *** antioxidant activity was evaluated using antioxidant assays of 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity,superoxide radical scavenging assay,2,2’-azino-bis-(3-ethyl)benzothiazoline-6-sulfonic acid,ferric reducing antioxidant power and reducing capacity *** antibacterial activity was done by agar well diffusion method against four Gram-positive,four Gram-negative bacteria and four ***:Different antioxidant assays showed different levels of activity in different parts and different solvent ***,acetone extract of stem showed the best antioxidant *** Gram-positive bacteria were more susceptible than Gram-negative bacteria and ***:The results indicated extract of Avicennia marina can be used as a promising source of natural antioxidant.

关键词： Avicennia marina Mangrove Antioxidant activity Total phenol content Total flavonoid content

Development of a Tribofidelic Human Heel Surrogate for Barefoot Slip Testing

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Journal of Bionic Engineering 2022年第2期19卷 429-439页

作者： Subhodip Chatterjee Arnab chanda Centre for Biomedical Engineering Indian Institute of Technology DelhiNew Delhi 110016India Department of Biomedical Engineering All India Institute of Medical ScienceNew Delhi 110029India

Barefoot slips contribute to over 37% of recurrent fall-related injuries across all age *** study slip risk across a wide range of flooring conditions,slip meters with barefoot surrogates(i.e.,sensors,as per ASTM standard nomenclature)such as animal skins and rubbers have been used to date,which exhibit biomechanical and frictional properties widely different from the barefoot human *** of a surrogate which can accurately simulate the human heel skin properties would be immensely beneficial for realistic assessment of barefoot slipping risk.A novel surrogate was developed using 3D scanning and printing,and biomimetics,which precisely simulates the biomechanical and frictional properties of the barefoot human heel *** slip testing was conducted with this surrogate on three common bathroom floorings and with six different *** of Friction(COF)results similar to human slipping experiments,high repeatability and reproducibility across wet and oily flooring conditions,were confirmed through experiments with the developed heel skin *** heel skin surrogate would be an indispensable model for accurate estimation of barefoot risk against slips and falls in bathrooms,bathtubs,and swimming pools.

关键词： Barefoot Surrogate Slip Fall Bathroom Bathtub

Optimal inventory policies for short life cycle successive generations’ technology products

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Journal of Management Analytics 2022年第2期9卷 261-286页

作者： Gaurav Nagpal Udayan chanda Department of Management BITS PilaniPilani CampusPilaniRajasthan 333031India

In this paper,a new Economic Order Quantity(EOQ)model for a successive generation of technology products has been *** classical EOQ model is based on the assumption that the demand rate is *** it cannot be used for technology products where competition-substitution among products is a usual *** address this problem,the EOQ model proposed in this article is considered a demand model for a technology product that follows the innovation-diffusion process.A numerical example has been illustrated and a comprehensive sensitivity analysis is conducted to understand the path of the optimal planning horizon and optimal costs under varied innovation and imitation *** sensitivity analysis of the introduction timing of the second generation has been performed to know the applicability of the model in actual *** behavior of the model has been discussed in detail in the numerical illustration section.

关键词： Economic order quantity innovation diffusion technological innovations coefficient of innovation coefficient of imitation successive generations

A Bayesian network model on the interlinkage between Socially Responsible HRM,employee satisfaction,employee commitment and organizational performance

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Journal of Management Analytics 2020年第1期7卷 105-138页

作者： Udayan chanda Praveen Goyal Department of Management BITS PilaniPilaniRajasthanIndia

In recent years several studies have been made to understand the impact of Socially Responsible HRM practices on Organizational *** progress,community and environment play an important role in the sustainable growth of an ***,organizations are always looking for the ways to improve the employee satisfaction vis-a-vis commitment to improve the *** studies have shown that as employees are important stakeholder,hence formulating proper Socially Responsible HRM practices may help organization to better the returns on *** main objective of the study is to identify the relationship among various dimensions of Socially Responsible HRM practices with dimensions of employee satisfaction,employee commitment and organizational performance for Indian manufacturing sector by using Bayesian Network *** of the study establish the relationship between dimensions of Socially Responsible HRM and Organizational Performance.

关键词： socially responsible HRM manufacturing industry employee satisfaction employee commitment organizational performance Bayesian network

Optimal ordering policy for short life-cycle products under credit financing with dynamic adoption in supply chain

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Journal of Management Analytics 2019年第3期6卷 269-301页

作者： Udayan chanda Alok Kumar Department of Management BITS PilaniPilaniIndia FORE School of Management New DelhiIndia

Traditional inventory models are mostly ignorant of the life cycle dynamics of a technology product;hence,they often fail to identify different dimensions of inventory *** paper attempts to investigate the relationship between adoption behavior of customers using life cycle dynamics and associated trade credit policies in order to optimize the total inventory *** demand model used in this paper treats sales as a function of awareness diffusion and *** is considered as a function of feedback effects from users/***’s optimal strategies for short life cycle product under credit financing were determined ***,numerical examples have been used to support the theoretical *** results have further been used to gain some managerial insights.

关键词： inventory stage-wise diffusion unfavorable information short life cycle trade credit