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International Journal of Ophthalmology(English edition) 2023年第3期16卷 375-381页

作者： sultan alzuhairy Department of Ophthalmology College of MedicineQassim UniversityBuraidah 51452Saudi Arabia

AIM:To compare intraocular pressure(IOP)measured via the trans palpebral IOP(tp IOP)method using a Diaton or with a Goldman applanation tonometer(GAT)and study the determinants of IOP difference in eyes undergoing transepithelial photorefractive keratectomy(TPRK)for ***:This cross-sectional validation study was held in 2020 in an eye hospital in Saudi *** was measured by Diaton and GAT before treatment,after one week,and one month of *** is considered if IOP difference by Diaton and GAT was less than±2 mm Hg *** IOP difference was tested if correlated to spherical equivalent(SE),central corneal thickness(CCT),age,gender,or tp ***:Totolly 200 myopic eyes of 100 patients were included in the *** mean difference of IOP measured by two methods before TPRK,1wk,and 1mo after TPRK were 0.790,-0.790,and-0.920 mm Hg,respectively(P<0.001).Diaton could measure IOP effectively 89.5%eyes before TPRK and 82%and 84%at 1wk and 1mo after TPTK,*** week 1,IOP differences were significantly correlated to baseline CCT(P=0.02)and tp IOP at week 1(P<0.001).One month after TPRK,only tp IOP was significantly correlated to the difference in IOP(P<0.001).CONCLUSION:Diaton is a good screening tool for IOP before *** helps in monitoring IOP after *** more practical,it is less efficient than *** eyes with high myopia and low tp IOP before surgery,IOP post-TPRK by Diaton and GAT could differ.

关键词： intraocular pressure Goldman applanation tonometry trans palpebral tonometry myopia transepithelial photorefractive keratectomy

Web Based Survey of Adult Population of West and Central Saudi Arabia about Cause and Management of Keratoconus

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Open Journal of Ophthalmology 2020年第4期10卷 341-350页

作者： sultan alzuhairy Raghad Hamza Moaz Alharbi Mohammed Alqadi Atheer Alharthi Khames Torki Alzahrani Ali Hassan Alshehri Department of Ophthalmology Qassim University Buraidah Saudi Arabia Medical College Taif University Taif Saudi Arabia Faculty of Health Sciences King Abdul Aziz University Jeddah Saudi Arabia Medical College Najran University Najran Saudi Arabia Ministry of Health Jeddah Saudi Arabia

Background: Keratoconus (KC) causes visual disability in young adults. To improve its early detection and compliance, improving the awareness of patients and their relatives is crucial. We present the level of awareness about KC among the adult population of western Saudi Arabia and its determinants. Methods: This web-based survey was carried out from June to August 2020 in urban and semi-urban areas in western Saudi Arabia. Demographic and eye ailment profiles were collected. To generate responses on the presentation, causes, management and prevention of KC, a five-point Likert scale was used. The logit values were calculated and graded into good and poor awareness. Awareness was associated with other determinants. Results: We surveyed 420 Saudi adults. The median logit score of awareness about KC among participants was 2.86 (inter quartile range (IQR) 0.86;2.95). The median score of knowledge about the causes and presentation of KC was 2.86 (IQR 1.1;2.86) and for management, it was 0.00 (IQR 0.00;0.18). The level of awareness was good in 286 participants (68.1%) and poor in 134 (31.9%). Residents of major cities (P Conclusions: Awareness about the presentation, causes and management of KC was good in two-thirds of adults but with some variation. Strategies to involve the community and stress health education need to be urgently implemented. Campaigns should target the male and semi-urban population in western Saudi Arabia.

关键词： Keratoconus Public Saudi Arabia Awareness

Dissolution mechanism and kinetics ofβ(Mg_(17)Al_(12))phases in AZ91 magnesium alloy

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Journal of Magnesium and Alloys 2024年第4期12卷 1581-1592页

作者： sultan Alomairy Department of Physics College of ScienceTaif UniversityTaif 21944Saudi Arabia

In this study,the phase transformations,crystallization kinetics and dissolution mechanism ofβphase(Mg_(17)Al_(12))in magnesium alloy AZ91 were investigated by optical microscopy,X-ray diffraction,differential scanning calorimetry and differential *** results indicate that this AZ91 alloy undergoes a phase transformation during aging,a discontinuous precipitation of theβphase(Mg_(17)Al_(12))at 150℃at the grain boundaries and another continuous at 350℃within the *** activation energy of the dissolution reaction of theβphase(Mg_(17)Al_(12))under non-isothermal conditions is 116.781 kJ/mol,while it is 129.7383 kJ/mol under isothermal *** Avrami coefficient,n,relevant for the dissolution kinetics of theβphase(Mg_(17)Al_(12))is 1.152 and 1.211 in the non-isothermal and isothermal conditions *** numerical coefficients m and Avrami n are 0.993 and 1.152.

关键词： AZ91 kinetics β(Mg_(17)Al_(12)) Activation energy Discontinuous precipitation Continuous precipitation DSC

Effect of mitomycin C on the corneal endothelial cells of Saudi patients with myopia after transepithelial photorefractive keratectomy:a two-armed cohort study

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 909-915页

作者： sultan H Alrashidi Department of Ophthalmology College of MedicineQassim UniversityBuraidah 51452Saudi Arabia

AIM:To study the effect of mitomycin C(MMC)applied during transepithelial photorefractive keratectomy(TPRK)on the corneal endothelium one week(W1)and three months(M3)after surgery and its ***:In this two-armed cohort study conducted in 2022,eyes treated with MMC during TPRK(group 1)were compared with eyes not treated with MMC(group 2).The corneal endothelial cell(EC)count,EC density(ECD;cells/mm2),average(μm2),standard deviation(μm2),coefficient of variation(CV%),ECmax,ECmin,and EC percentage of hexagonality were estimated at W1 and *** postoperative changes in the EC count in the two groups were compared and correlated with the other independent ***:Group 1 had 26 eyes,and group 2 had 78 *** TPRK indices were significantly higher for the eyes in group 1 than for those in group *** MMC usage was not a significant predictor of the change in ECD(P=0.644),change in CV(P=0.374),and change in the percentage of hexagonality of EC(P=0.164)at ***,the use of MMC was a significant predictor of changes in CV(P=0.014)and the change in the percentage of hexagonality of EC(P=0.039)at *** duration of laser exposure and the size of the optical zone influenced the correlation of MMC use with the changes in EC indices,***:The use of MMC doesn’t affect ECD,CV,and percentage of hexagonality at W1 if other surgical indices are *** M3 after operating myopic eyes by TPRK,MMC significantly influence the CV and percentage of *** duration of the laser application and the size of the optical zone should be considered when determining the effect of MMC on the EC indices.

关键词： transepithelial photorefractive keratectomy mitomycin-C corneal endothelium

Antimicrobial,antibiofilm,angiogenesis,anti-inflammatory,and wound healing activities of zinc nanoparticles green synthesized using Ferula macrecolea extract

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Asian Pacific Journal of Tropical Biomedicine 2024年第6期14卷 259-268页

作者： sultan F.Alnomasy Department of Medical Laboratories Sciences College of Applied Medical SciencesShaqra UniversityAl-Quwayiyah 19257Saudi Arabia

Objective:To assess the antimicrobial,antibiofilm,anti-inflammatory,angiogenic,and wound healing activities of zinc nanoparticles(ZNPs)green synthesized using Ferula macrecolea ***:The green synthesis was conducted using the precipitation ***,the minimum inhibitory concentration(MIC),minimum bactericidal concentration(MBC),and minimum biofilm inhibition concentration 50%(MBIC50)of ZNPs against Staphylococcus aureus(***)and Pseudomonas aeruginosa(***)were *** effects of ZNPs on the gene expressions of Staphylococcus spp.[intracellular adhesion A(icaA)and D(icaD)]and ***(rhlI and rhlR)were investigated using quantitative real-time *** addition,the effects of ZNPs on wound healing,angiogenesis,and anti-inflammatory markers were ***:The green-synthesized ZNPs demonstrated significant antimicrobial efficacy against *** and *** biofilm formation in *** and *** was also inhibited by ZNPs with MBIC50 values of 3.30μg/mL and 2.08μg/mL,***,ZNPs downregulated the expression of biofilm-related genes icaA,icaD,rhlI,and rhlR in the tested *** also demonstrated promising in vitro wound healing effects by promoting fibroblast cell proliferation and wound closure in a dose-dependent manner.A significant increase in the expression of HLA-G5 and VEGF-A genes as well as a marked decrease in the expression of NF-κB,IL-1β,and TNF-αgenes were observed in cells treated with ZNPs compared to the control group(P<0.05).Conclusions:ZNPs display promising antibacterial effects against *** and *** and wound-healing effects by inhibiting biofilm formation,inducing angiogenesis,and reducing ***,further studies must be conducted to specify the accurate mechanisms of action and toxicity of ZNPs.

关键词： Wound healing Antibacterial Angiogenesis Nanomedicine Ferula macrecolea Inflammation

Utilizing N-hydroxy-9-octadecenamide as a collector in flotation separation of bastnaesite and fluorite

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Journal of Rare Earths 2024年第8期42卷 1620-1628,I0008页

作者： Zhihao Guo sultan Ahmed Khoso Mengjie Tian Wei Sun School of Minerals Processing and Bioengineering Central South UniversityChangsha410083China State Key Laboratory of Mineral Processing Beijing102600China Hubei Key Laboratory for Efficient Utilization and Agglomeration of Metallurgic Mineral Resources Wuhan430081China Key Laboratoryof Hunan Province for Cleanand Efficient Utilization of Strategic Calcium-containing Mineral Resources Central South UniversityChangsha410083China Department of Mining Engineering Mehran University of Engineering&TechnologyJamshoro76062Pakistan

Bastnaesite((Ce,La,Pr,Nd)CO_(3)F) is a significant light rare earth mineral found in nature,known for its fine-grained *** is commonly employed for the recovery of fine-grained bastnaesite *** serve as an essential flotation reagent that enhance the surface hydrophobicity of target minerals.A novel collector,N-hydroxy-9-octadecenamide(N-OH-9-ODA),was synthesised in this study.N-OH-9-ODA exhibits superior selectivity compared to the traditional collector oleic acid in the flotation separation of bastnaesite and *** experimental and co mputational results indicate that N-OH-9-ODA exhibits superior selectivity due to its higher adsorption affinity for bastnaesite surface compared to fluorite *** zeta potential and the binding energies of the Ce 3d peaks in the X-ray photoelectron spectrum(XPS) of bastnaesite surface exhibit significant ***,fluorite surface demonstrates minimal alterations in its zeta potential and the binding energies of the Ca 2p peaks in its XPS after its interaction with N-OH-9-ODA.

关键词： Bastnaesite Collector Hydroxamic acids N-hydroxy-9-octadecenamide Oleic acid Rare earths

Novel Framework for an Intrusion Detection System Using Multiple Feature Selection Methods Based on Deep Learning

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Tsinghua Science and Technology 2024年第4期29卷 948-958页

作者： A.E.M.Eljialy Mohammed Yousuf Uddin sultan Ahmad Department of Information Systems College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharjSaudi Arabia Department of Computer Science College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharjSaudi Arabiaand also with University Center for Research and Development(UCRD)Department of Computer Science and EngineeringChandigarh UniversityPunjabIndia

Intrusion detection systems (IDSs) are deployed to detect anomalies in real time. They classify a network’s incoming traffic as benign or anomalous (attack). An efficient and robust IDS in software-defined networks is an inevitable component of network security. The main challenges of such an IDS are achieving zero or extremely low false positive rates and high detection rates. Internet of Things (IoT) networks run by using devices with minimal resources. This situation makes deploying traditional IDSs in IoT networks unfeasible. Machine learning (ML) techniques are extensively applied to build robust IDSs. Many researchers have utilized different ML methods and techniques to address the above challenges. The development of an efficient IDS starts with a good feature selection process to avoid overfitting the ML model. This work proposes a multiple feature selection process followed by classification. In this study, the Software-defined networking (SDN) dataset is used to train and test the proposed model. This model applies multiple feature selection techniques to select high-scoring features from a set of features. Highly relevant features for anomaly detection are selected on the basis of their scores to generate the candidate dataset. Multiple classification algorithms are applied to the candidate dataset to build models. The proposed model exhibits considerable improvement in the detection of attacks with high accuracy and low false positive rates, even with a few features selected.

关键词： random forest feature selection decision tree software-defined network logistic regression intrusion detection system XGB classifier AdaBoost

Enabling Efficient Data Transmission in Wireless Sensor Networks-Based IoT Application

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Computers, Materials & Continua 2024年第6期79卷 4197-4218页

作者： Ibraheem Al-Hejri Farag Azzedin sultan Almuhammadi Naeem Firdous Syed Information and Computer Science Department King Fahd University of Petroleum andMineralsDhahran31261Saudi Arabia Center for Cyber Resilience and Trust(CREST) Deakin UniversityGeelong3220Australia

The use of the Internet of Things(IoT)is expanding at an unprecedented scale in many critical applications due to the ability to interconnect and utilize a plethora of wide range of *** critical infrastructure domains like oil and gas supply,intelligent transportation,power grids,and autonomous agriculture,it is essential to guarantee the confidentiality,integrity,and authenticity of data collected and ***,the limited resources coupled with the heterogeneity of IoT devices make it inefficient or sometimes infeasible to achieve secure data transmission using traditional cryptographic ***,designing a lightweight secure data transmission scheme is becoming *** this article,we propose lightweight secure data transmission(LSDT)scheme for IoT *** consists of three phases and utilizes an effective combination of symmetric keys and the Elliptic Curve Menezes-Qu-Vanstone asymmetric key agreement *** design the simulation environment and experiments to evaluate the performance of the LSDT scheme in terms of communication and computation *** and performance analysis indicates that the LSDT scheme is secure,suitable for IoT applications,and performs better in comparison to other related security schemes.

关键词： IoT lightweight computation complexity communication overhead cybersecurity threats threat prevention secure data transmission Wireless Sensor Networks(WSNs) elliptic curve cryptography

Back to the drawing board:Overview of the next generation of combination therapy for inflammatory bowel disease

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World Journal of Gastroenterology 2024年第25期30卷 3182-3184页

作者： Jeffrey A Lowell Michael J Farber Keith sultan Department of Medicine Zucker School of Medicine at HofstraNorth Shore University Hospital-Long Island Jewish Medical CenterManhassetNY 11030United States Preclinical Studies New York Institute of Technology College of Osteopathic MedicineGlen HeadNY 11545United States Division of Gastroenterology Northwell HealthNorth Shore University Hospital and Long Island Jewish Medical CenterGreat NeckNY 10021United States

Inflammatory bowel disease(IBD)is entering a potentially new era of combined *** et al provide an insightful review of the current state of combination therapy,with a focus on the use of a combined biologic and immunomodulator,as well as emerging data on the future potential of dual-biologic therapy(DBT).While current evidence for DBT is limited,encouraging safety profiles and ongoing trials suggest a brighter future for this *** importance of controlled trials should be stressed in establishing new treatment *** prospective randomized trials of DBT and perhaps future combinations of biologics and small molecule therapies will hopefully guide the next generation of IBD care.

关键词： Inflammatory bowel disease Biologics Immunomodulators Dual-therapy Combination therapy

Ranking Evaluation and Aging Assessment of Pump Stations at Fayoum City，Egypt

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Ranking Evaluation and Aging Assessment of Pump Stations at ...

作者： sultan Adel Abdelhamid Kotb 扬州大学

学位级别：硕士