检索结果-南通市图书馆

Nonalcoholic fatty liver disease is associated with coronary artery disease in Koreans

World Journal of Gastroenterology 2013年第38期19卷 6453-6457页

作者： Dae Hee choi Sung Joon Lee Chang Don Kang Myoung Ok Park Dong Wook choi Tae suk Kim Wonho Lee Byung Ryul Cho Yong Hoon Kim Bong-ki Lee Dong Ryeol Ryu Ji Won Lee Department of Internal Medicine Kangwon National University School of Medicine Department of Radiology Kangwon National University School of Medicine

AIM:To investigate whether nonalcoholic fatty liver disease(NAFLD)affects coronary artery disease(CAD)and identify candidate ***:Patients who underwent coronary angiography were consecutively *** patients were classified into four groups by coronary artery stenosis:A,insignificant;B,one-vessel disease;C,two-vessel disease;and D,three-vessel *** ultrasonography was performed to determine the presence of a fatty liver and categorize by grade:0,no evidence;1,mild;2,moderate;and 3,*** measured not only known CAD risk factors,but also serum insulin,HOMA-index,adiponectin,interleukin-6,tumor necrosis factor-αand high-sensitivity C-reactive protein ***:Of the 134 patients who met the inclusion criteria,82(61.2%)had ultrasonographically diagnosed *** the 46 patients with CAD,37(80.4%)had evidence of a fatty *** two groups(A vs B-D)were significantly different in terms of age,total cholesterol,triglycerides,low-density lipoprotein levels and fatty *** artery stenosis was strongly associated with fatty liver in a grade-dependent manner(P=0.025).In binary logistic regression,NAFLD was a significant independent predictor of CAD(P=0.03,OR=1.685;95%CI:1.051-2.702).Among the candidate mediators,the serum adiponectin level showed a trend toward lowering based on CAD progression(P=0.071).CONCLUSION:NAFLD is an independent risk factor for CAD in a grade-dependent ***,adiponectin might be related to the pathogenesis of NAFLD.

关键词： Nonalcoholic fatty liver disease Coronary artery disease Coronary angiography Adiponectin Insulin resistance

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessment of Sesquiterpene Lactones in Lettuce(Lactuca sativa L.)Germplasm

Assessment of Sesquiterpene Lactones in Lettuce(Lactuca sati...

引用

2014年中国作物学会学术年会

作者： Jeong-Ro Lee Susanna-choi Na-Young Ro Ho-Cheol Ko Jeong-suk Sung Taek-Ryun Kown Young-Yi Lee Jae-Gyun Gwag National Agrobiodiversity Center National Academy of Agricultural ScienceRural Development Administration

Sesquiterpene lactones(SLs) are a group of over 500 compounds,characteristic of the Asteraceae and sporadically occurring in other plant *** are interesting from the chemical and chemotaxonomic point of view,and show anti-tumour,anti-leukaemic,anti-cardiovascular disease,reduction of inflammation,anti-microbial *** have been indicated as a property connected to appetite and digestion promotion in *** of folk medicines also implicate SLs as the active ingredient in many treatments for other ailments such as diarrhea,burns,influenza,and *** of 266 accessions of lettuce(Lactuca sativa) germplasm introduced from 43 countries conserved in RDA genebank was used this *** was extracted by methanol from freeze-dried lettuce leaves,sampled at bolting *** SLs compounds,lactucin,lactucopicrin and 8-deoxylactucin,was quantified by *** range of lactucin content showed trace 120.0 μg/g of dried leaves and average was 19.0±1.3,and distribution range trace 488.1 μg and average 16.8±2.9 in 8-deoxylactucin content,and distribution range trace1,189.0 μg and average 195.2±9.9 in lactucopicrin content,and distribution range17.4,299.9 μg and average 231.0±11.4 in total SLs *** lettuce have lowest average total SLs content,on the contrary romaine have highest SLs content and ***,wild relatives,have higher than *** accessions have lowest average total SLs content and Great Britain accessions showed highest SLs *** showed higher than bred *** two accessions have more than500μg of total SLs and seventeen accessions have less than 50μg of total *** germplasm can be used as low SLs content cultivar breeding or high SLs content cultivar breeding sources as well as research materials for medical treatment such as,anti-tumour,anti-leukaemic,and antimicrobial activities,etc.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Different risk factors for advanced colorectal neoplasm in young adults

引用

World Journal of Gastroenterology 2016年第13期22卷 3611-3620页

作者： Ji Yeon Kim Yoon suk Jung Jung Ho Park Hong Joo Kim Yong Kyun Cho Chong Il Sohn Woo Kyu Jeon Byung Ik Kim Kyu Yong choi Dong Il Park Comprehensive Health Care Center Korea Cancer Center Hospital Korea Institute of Radiological and Medical Sciences Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine

AIM: To compare the risk of developing advanced colorectal neoplasm(ACRN) according to age in ***: A total of 70428 Koreans from an occupational cohort who underwent a colonoscopy between 2003 and 2012 at Kangbuk Samsung Hospital were retrospectively selected. We evaluated and compared odds ratios(OR) for ACRN between the young-adults(YA < 50 years) and in the older-adults(OA ≥ 50 years). ACRN was defined as an adenoma ≥ 10 mm in diameter, adenoma with any component of villous histology, high-grade dysplasia, or invasive ***: In the YA group, age(OR = 1.08, 95%CI: 1.06-1.09), male sex(OR = 1.26, 95%CI: 1.02-1.55), current smoking(OR = 1.37, 95%CI: 1.15-1.63), family history of colorectal cancer(OR = 1.46, 95%CI: 1.01-2.10), diabetes mellitus related factors(OR = 1.27, 95%CI: 1.06-1.54), obesity(OR = 1.23, 95%CI: 1.03-1.47), CEA(OR = 1.04, 95%CI: 1.01-1.09) and low-density lipoprotein-cholesterol(OR = 1.01, 95%CI: 1.01-1.02) were related with an increased risk of ACRN. However, age(OR = 1.08, 95%CI: 1.06-1.09), male sex(OR = 2.12, 95%CI: 1.68-2.68), current smoking(OR = 1.38, 95%CI: 1.12-1.71), obesity(OR = 1.34, 95%CI: 1.09-1.65) and CEA(OR = 1.05, 95%CI: 1.01-1.09) also increased the risk of ACRN in the OA ***: The risks of ACRN differed based on age group. Different colonoscopic screening strategies are appropriate for particular subjects with risk factors for ACRN, even in subjects younger than 50 years.

关键词： Young-adult Advanced colorectal neoplasm Risk factors Age Metabolic abnormality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

视乳头旁葡萄肿19例病例的临床特点和视力预后

引用

美国医学会眼科杂志（中文版） 2006年第4期18卷 246-247页

作者： Seok Hwan Kim Mi Young choi Young suk Yu Jang Won Huh 陈慧瑾（译）

目的：研究患有视乳头旁葡萄肿的病例的临床特点和视力预后。方法：回顾研究在1991年1月1日-2003年12月31日间，在韩国汉城市汉城国立大学儿童医院诊断出的视乳头旁葡萄肿的病例。记录视力以及相关的眼部及全身异常。

关键词：视力预后临床特点葡萄肿乳头旁病例医院诊断

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

STANDARDIZATION OF LED-BASED FLAT PANEL FOR USE IN GENERAL LIGHTING

STANDARDIZATION OF LED-BASED FLAT PANEL FOR USE IN GENERAL L...

引用

The First Tripartite Lighting SCI-TECH Forum of China,Japan and Republic of Korea

作者： Sang-Kyoo Jeon Mee-Ryoung Cho suk-Joon choi Jae-Yeop Rho Se-Hyun Lee Sang-Wuk Shin Myung-Keun Hwang Do-Young Lee Seong-Yong Yang Korea Institute of Lighting Technology 187-7 Dodang-dong Wonmi-guBucheon-cityGyeonggidoSouth Korea

＜正＞Many measurement methods for white LEDs have been studied in the filed of lighting,extensively, since it has developed and used as the wide range of ***,the studies of standardization of LED-based flat panel for general lighting have not been studied a *** this paper,we present and analyze the applicable standards of LED-based flat panel for use in general lighting.

关键词： Light Emitting Diode (LED) General Lighting Flat Panel Standard

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Hepatic arterial infusion chemotherapy in hepatocellular carcinoma with portal vein tumor thrombosis

引用

World Journal of Gastroenterology 2013年第29期19卷 4679-4688页

作者： Do Seon Song Si Hyun Bae Myeong Jun Song Sung Won Lee Hee Yeon Kim Young Joon Lee Jung suk Oh Ho Jong Chun Hae Giu Lee Jong Young choi Seung Kew Yoon Department of Internal Medicine College of Medicine The Catholic University of Korea Seoul 137-040 South Korea Department of Radiology College of Medicine The Catholic University of Korea Seoul 137-040 South Korea

AIM: To evaluate the prognostic factors and efficacy of hepatic arterial infusion chemotherapy in hepatocellular carcinoma with portal vein tumor thrombosis. METHODS: Fifty hepatocellular carcinoma (HCC) patients with portal vein tumor thrombosis (PVTT) were treated using hepatic arterial infusion chemotherapy (HAIC) via a subcutaneously implanted port. The epirubicin-cisplatin-5-fluorouracil (ECF) chemotherapeutic regimen consisted of 35 mg/m 2 epirubicin on day 1, 60 mg/m 2 cisplatin for 2 h on day 2, and 500 mg/m 2 5-fluorouracil for 5 h on days 1-3. The treatments were repeated every 3 or 4 wk. RESULTS: Three (6%) of the 50 patients achieved a complete response (CR), 13 (26%) showed partial responses (PR), and 22 (44%) had stable disease (SD).The median survival and time to progression were 7 and 2 mo, respectively. After 2 cycles of HAIC, CR was achieved in 1 patient (2%), PR in 10 patients (20%) and SD in 26 patients (52%). Significant pre-treatment prognostic factors were a tumor volume of < 400 cm 3 (P = 0.01) and normal levels of protein induced by vitamin K absence or antagonist (PIVKA)-Ⅱ (P = 0.022). After 2 cycles of treatment, disease control (CR + PR + SD) (P = 0.001), PVTT response (P = 0.003) and α-fetoprotein reduction of over 50% (P = 0.02) were independent factors for survival. Objective response (CR + PR), disease control, PVTT response, and combination therapy during the HAIC were also significant prognostic factors. Adverse events were tolerable and successfully managed. CONCLUSION: HAIC may be an effective treatment modality for advanced HCC with PVTT in patients with tumors < 400 cm 3 and good prognostic factors.

关键词： Hepatocellular carcinoma Hepatic arterial infusion chemotherapy Portal vein tumor thrombosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A feasible modified biopsy method for tissue diagnosis of gastric subepithelial tumors

引用

World Journal of Gastroenterology 2013年第29期19卷 4752-4757页

作者： Jung Ho Kim Jun-Won Chung Minsu Ha Min Young Rim Jong Joon Lee Jungsuk An Yoon Jae Kim Kyoung Oh Kim Kwang An Kwon Dong Kyun Park Yeon suk Kim Duck Joo choi Department of Internal Medicine Gachon University Gil Medical Center Incheon 405-760 South Korea Department of Pathology Gachon University Gil Medical Center Incheon 405-760 South Korea

AIM: To evaluate the diagnostic yield and safety of a modified technique for the histological diagnosis of subepithelial tumors (SETs). METHODS: A retrospective review of patients who underwent a modified technique for the histological diagnosis of gastric SETs, consisting of a mucosal incision with a fixed flexible snare (MIF) and deep-tissue biopsy under conventional endoscopic view, from January 2012 to January 2013 was performed. Eleven patients with gastric SETs 10-30 mm in diameter and originating from the third or fourth layer on endoscopic ultrasonography were included. RESULTS: The mean age was 59.8 (range, 45-76) years, and 5 patients were male. The mean size of the SETs was 21.8 (range, 11-30) mm. The number of biopsy specimens was 6.3 (range 5-8). The mean procedure time was 9.0 min (range, 4-17 min). The diagnostic yield of MIF biopsies was 90.9% (10/11). The histological diagnoses were leiomyoma (4/11, 36.4%), aberrant pancreas (3/11, 27.3%), gastrointestinal stromal tumors (2/11, 18.2%), an inflammatory fibrinoid tumor (1/11, 9.1%); one result was non-diagnostic (1/11, 9.1%). There were six mesenchymal tumors; the specimens obtained in each case were sufficient for an immunohistochemical diagnosis. There was no major bleeding, but one perforation occurred that was successfully controlled by endoscopic clipping. CONCLUSION: The MIF biopsy was simple to perform, safe, and required a shorter procedure time, with a high diagnostic yield for small SETs.

关键词： Subepithelial tumors Stomach Biopsy Endoscopy Diagnostic techniques

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diversity of bacterial and fungal strains isolated from coastal sand-dunes in Korea

Diversity of bacterial and fungal strains isolated from coas...

引用

中国菌物学会2016年学术年会

作者： Minji Jeong Ki-Eun Lee Min-Kyeong Kim Kyoung-Mi Kim Hyun Kim Yoon-Jong Nam Yoosun Oh Hyerim choi Nan-Yeong Lee Jong-Guk Kim Myung-suk Kang Department of Life Sciences and Biotechnology Institute for MicroorganismsKyungpook National University

＜正＞Microbial cultures were collected from roots of plants（11 species）in three coastal sand-dunes（Sinduri,Goraebul,Sowhang）in *** amplification of the 16S r RNA genes were conducted using the forward primer 27F and the reverse primer1492R and sequencing of the genes was performed by using Big Dye Terminator cycle Sequencing Ready Reaction Kit.160 isolates were identified:Sinduri coastal

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Endoscopic submucosal dissection for early gastric cancer with undifferentiated-type histology:A meta-analysis

引用

World Journal of Gastroenterology 2015年第19期21卷 6032-6043页

作者： Chang Seok Bang Gwang Ho Baik In Soo Shin jing Bong Kim Ki Tae suk Jai Hoon Yoon Yeon Soo Kim Dong Joon Kim Woon Geon Shin Kyung Ho Kim Hak Yang Kim Hyun Lim Ho Seok Kang Jong Hyeok Kim jin Bae Kim Sung Won Jung Sea Hyub Kae Hyun Joo Jang Min Ho choi Department of Internal Medicine Hallym University College of Medicine College of Education Jeonju University

AIM: To evaluate the efficacy and safety of endoscopicsubmucosal dissection(ESD) for early gastric cancer(EGC) with undifferentiated-type ***: A systematic literature review was conducted using the core databases. Complete resection,curative resection, en bloc resection, recurrence and adverse event rate were extracted and analyzed. A random effect model was applied. The methodological quality of the enrolled studies was assessed using the Newcastle-Ottawa Scale. Publication bias was evaluated using a funnel plot, the trim and fill method, Egger's test,and a rank correlation ***: Fourteen retrospective studies between2009 and 2014 were identified(972 EGC lesions with undifferentiated-type histology). The total en bloc and complete resection rates were estimated as92.1%(95%CI: 87.4%-95.2%) and 77.5%(95%CI:69.3%-84%), respectively. The total curative resection rate was 61.4%(95%CI: 44.5%-75.9%). The overall recurrence rate was 7.6%(95%CI: 3.4%-16%).Limited to histologically diagnosed expanded-criteria lesions, the en bloc and complete resection rates were91.2% and 85.6%, respectively. The curative resection rate was 79.8%.CONCLUSION: In this analysis, ESD is a technically feasible treatment modality for EGC with undifferentiatedtype histology. Long-term studies are needed to confirm these therapeutic outcomes.

关键词： Carcinoma Endoscopic submucosal dissection Endoscopy Gastric cancer Meta-analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Higher plasma bilirubin predicts veno-occlusive disease in early childhood undergoing hematopoietic stem cell transplantation with cyclosporine

引用

World Journal of Transplantation 2016年第2期6卷 403-410页

作者： Kwi suk Kim Aree Moon Hyoung jin Kang Hee Young Shin Young Hee choi Hyang Sook Kim Sang Geon Kim Department of Pharmacy Seoul National University Hospital College of Pharmacy Duksung Women’s University Department of Pediatrics Cancer Research InstituteSeoul National University College of Medicine College of Pharmacy Dongguk University College of Pharmacy and Research Institute of Pharmaceutical Sciences Seoul National University

AIM: To analyze the association between plasma bilirubin levels and veno-occlusive disease(VOD) in non-adult patients undergoing hematopoietic stem cell transplantation(HSCT) during cyclosporine ***: A total of 123 patients taking cyclosporinewere evaluated using an electronic medical system at the Seoul National University Children's Hospital from the years 2004 through 2011. Patients were grouped by age and analyzed for incidence and type of adverse drug reactions(ADRs) including VOD. RESULTS: The HSCT patients were divided into three age groups: G#1 ≥ 18; 9 ≤ G#2 ≤ 17; and G#3 ≤ 8 years of age). The majority of transplant donor types were cord blood transplantations. Most prevalent ADRs represented acute graft-vs-host disease(a GVHD) and VOD. Although the incidences of a GVHD did not vary among the groups, the higher frequency ratios of VOD in G#3 suggested that an age of 8 or younger is a risk factor for developing VOD in HSCT patients. After cyclosporine therapy, the trough plasma concentrations of cyclosporine were lower in G#3 than in G#1, indicative of its increased clearance. Moreover, in G#3 only, a maximal total bilirubin level(BILmax) of ≥ 1.4 mg/d L correlated with VOD incidence after cyclosporine therapy. CONCLUSION: HSCT patients 8 years of age or younger are more at risk for developing VOD, diagnosed as hyperbilirubinemia, tender hepatomegaly, and ascites/weight gain after cyclosporine therapy, which may be represented by a criterion of plasma BILmax being ≥ 1.4 mg/d L, suggestive of more sensitive VOD indication in this age group.

关键词： Hematopoietic stem cell transplantation Veno-occlusive disease Cyclosporine Adverse drug reaction Total bilirubin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：