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Photonics Research 2014年第3期2卷 S0025-S0033页

作者： Hyunil Byun Jinkwon Bok Kwansik Cho Keunyeong Cho Hanmei Choi Jinyong Choi Sanghun Choi Sangdeuk Han Seokyong Hong Seokhun Hyun TJJeong Ho-Chul Ji In-Sung Joe Beomseok Kim Donghyun Kim Junghye Kim Jeong-Kyoum Kim Kiho Kim Seong-Gu Kim Duanhua Kong Bongjin Kuh Hyuckjoon Kwon Beomsuk Lee Hocheol Lee Kwanghyun Lee Shinyoung Lee Kyoungwon Na Jeongsik Nam Amir Nejadmalayeri Yongsang park Sunil Parmar Junghyung Pyo Dongjae Shin Joonghan Shin Yong-hwack Shin Sung-Dong suh.Honggoo Yoon Yoondong park Junghwan Choi Kyoung-Ho Ha Gitae Jeong Samsung Electronics 1 SamsungjeonjaroHwasungshiGyoung-gido445-330South Korea

We present photonics technology based on a bulk-Si substrate for cost-sensitive dynamic random-access memory(DRAM)optical interface *** summarize the progress on passive and active photonic devices using a local-crystallized Si waveguide fabricated by solid phase epitaxy or laser-induced epitaxial growth on bulk-Si *** process of integration of a photonic integrated circuit(IC)with an electronic IC is demonstrated using a 65 nm DRAM periphery process on 300 mm wafers to prove the possibility of seamless integration with various complementary metal-oxide-semiconductor *** the bulk-Si photonic devices,we show the feasibility of high-speed multidrop interface:the Mach–Zehnder interferometer modulators and commercial photodetectors are used to demonstrate four-drop link operation at 10 Gb∕s,and the transceiver chips with photonic die and electronic die work for the DDR3 DRAM interface at 1.6 Gb∕s under a 1∶4 multidrop configuration.

关键词： interferometer waveguide interface

原发性中枢神经系统淋巴瘤:全身CT和FDG PET/CT的首次系统性成像的诊断率

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国际医学放射学杂志 2019年第5期 618-619页

作者： C.H.suh.H.S.Kim J.E.park S.C.Jung C.G.Choi S.J.Kim 赵思修 Department of Radiology and Research Institute of Radiology University of Ulsan College of Medicine Asan Medical Center

摘要对疑似原发性中枢神经系统淋巴瘤(PCNSL)缺乏最新指南。目的研究对于疑似PCNSL病人进行胸部、腹盆腔增强CT和/或全身18F-脱氧葡萄糖(FDG) PET/CT等首次

关键词：原发性中枢神经系统淋巴瘤 FDG PET/CT CT PET

首诊非小细胞肺癌脑转移预测因子的鉴别：一项单中心队列研究

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国际医学放射学杂志 2022年第2期 245-245页

作者： S.park S.M.Lee Y.Ahn M.Kim C.H.suh.K.H.Do 麻足里伟

摘要目的根据首诊非小细胞肺癌（NSCLC）是否可切除分为2组并分析其临床和胸部CT分期特征对预测脑转移的作用。方法回顾性分析2017年11月—2018年10月首

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在韩国,实践中西罗莫司洗脱支架冠状动脉介入治疗的1年结局优于紫杉醇洗脱支架

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世界核心医学期刊文摘（心脏病学分册） 2007年第8期3卷 48-49页

作者： suh.J.-W. park J.-S. Cho H.-J. 马超 Department of Internal Medicine Seoul National University College of Medicine South Korea

目的:随机试验已证实了药物洗脱支架(DES)的疗效,但西罗莫司洗脱支架(SES)和紫杉醇洗脱支架(PES)在未经选择患者中的疗效差别尚存在争议。因此,本研究旨在探讨这两种DES的临床和血管造影结局。方法:对2003年3月至2004年3月在两个中心接... 详细信息

目的:随机试验已证实了药物洗脱支架(DES)的疗效,但西罗莫司洗脱支架(SES)和紫杉醇洗脱支架(PES)在未经选择患者中的疗效差别尚存在争议。因此,本研究旨在探讨这两种DES的临床和血管造影结局。方法:对2003年3月至2004年3月在两个中心接受DES治疗的所有连续患者进行分析。结果:分析了接受两种DES治疗的440例患者(共519处病变;353处病变/296例患者接受SES,166处病变/144例患者接受PES)。

关键词：紫杉醇洗脱支架介入治疗药物洗脱支架支架直径靶病变血运重建血管造影联合终点心脏事件再狭

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Management of entecavir-resistant chronic hepatitis B with adefovir-based combination therapies

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World Journal of Gastroenterology 2015年第38期21卷 10874-10882页

作者： Hyoung Su Kim Hyung Joon Yim Myoung Kuk Jang Ji Won park Sang Jun suh.Yeon Seok Seo Ji Hoon Kim Bo Hyun Kim Sang Jong park Sae Hwan Lee Sang Gyune Kim Young Seok Kim Jung Il Lee Jin-Woo Lee In Hee Kim Tae Yeob Kim Jin-Wook Kim Sook-Hyang Jeong Young Kul Jung Hana park Seong Gyu Hwang Department of Internal Medicine Hallym University College of Medicine Department of Internal Medicine Korea University Ansan Hospital Department of Internal Medicine Korea University Medical College Department of Internal Medicine Bundang Jesaeng Hospital Department of Internal Medicine Soon Chun Hyang University College of Medicine Department of Internal Medicine Inha University School of Medicine Department of Internal Medicine Chonbuk National University Medical School Department of Internal Medicine Hanyang University College of Medicine Department of Internal Medicine Seoul National University College of Medicine Department of Internal Medicine Gachon University School of Medicine Department of Internal Medicine CHA Bundang Medical CenterCHA University

AIM: To evaluate the long-term efficacy adefovir(ADV)-based combination therapies in entecavir(ETV)-resistant chronic hepatitis B(CHB) patients. METHODS: F i fty CHB pat ient s wi t h genotypic resistance to ETV at 13 medical centers in South Korea were included for the analysis. All the patients received rescue therapy with the combination of ADV plus ETV(ADV/ETV,n = 23) or ADV plus lamivudine(LMV)(ADV/LMV,n = 27) for more than 12 mo. Patients were monitored at least every 3-4 mo during ADV-based combination therapy by clinical examination as well as biochemical and virological assessments. Hepatitis B virus(HBV) DNA levels were measured by realtime PCR and logarithmically transformed for analysis. Cumulative rates of virologic response(VR; HBV DNA < 20 IU/m L) were calculated using the Kaplan-Meier method,and the difference was determined by a logrank test. Multivariate logistic regression and Cox proportional hazards models were used to identify independent risk factors significantly associated with short-term and long-term VR,***: Baseline median HBV DNA levels were 5.53(2.81-7.63) log10 IU/m L. The most commonly observed ETV genotypic mutation sites were rt184 and rt202. Patients were treated for a median of 27(12-45) mo. Overall,cumulative VR rates at 6,12,24,and 36 mo were 26%,36%,45%,and 68%,respectively. Patients treated with the ADV/ETV combination showed higher cumulative VR rates(35%,43%,65%,and 76%,respectively) than those with the ADV/LAM combination(18%,30%,30%,and 62%,respectively; P = 0.048). In the multivariate analysis,low baseline HBV DNA levels(< 5.2 log10 IU/m L) and initial virologic response at 3 mo(IVR-3; HBV DNA < 3.3 log10 IU/m L after 3 mo) were independent predictive factors for VR. Patients with favorable predictors achieved cumulative VR rates up to 90% at 36 mo. During the same period,the cumulative incidence of virologic breakthrough was as low as 6% in patients with the both favorable ***: If tenof

关键词： Adefovir Chronic hepatitis B Entecavir Lamivudine

Case of bronchoesophageal fistula with gastric perforation due to multidrug-resistant tuberculosis

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World Journal of Gastrointestinal Surgery 2014年第12期6卷 253-258页

作者： Chan Sung park Kwang won Seo Chang Ryul park Yang Won Nah Jae Hee suh Department of Internal medicine Ulsan University Hospital University of Ulsan College of Medicine Department of Thoracic and Cardiovascular Surgery Ulsan University Hospital Department of General Surgery Ulsan University Hospital Department of Pathology Ulsan University Hospital

Gastric perforation and tuberculous bronchoesophageal fistula(TBEF) are very rare complications of extrapulmonary tuberculosis(TB). We present a case of pulmonary TB with TBEF and gastric perforation caused by a multidrug-resistant tuberculosis strain in a nonacquired immune deficiency syndrome male *** patient underwent total gastrectomy with Rouxen-Y end-to-side esophagojejunostomy and feeding jejunostomy during intravenous treatment with anti-TB medication, and esophageal reconstruction with colonic interposition and jejunocolostomy were performed successfully after a full course of anti-TB *** recent therapies for TBEF have favored medication, patients with severe stenosis or perforation require surgery and medication with anti-TB drugs basedupon adequate culture and drug susceptibility testing.

关键词： tuberculosis medication perforation fistula gastrectomy colonic intravenous susceptibility tuberculous stomach

植物性发酵乳杆菌对免疫系统的生理活性、抗高血糖和促进肠蠕动的影响

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中国微生态学杂志 2013年第7期25卷 782-788页

作者： park Soo-hyun Sim Yun-beom suh.Hong-won Nam Kyung-sung Lee Dong-jin Choi Se-young Lee Deuk-sik 姜玲翰林大学天然药物研究所药理学系汉中大学食品服务部 Well-beingLS有限公司生命科学学院理博健康科学推广中心生物工程部

研究植物源性发酵乳杆菌对免疫系统生理活性、抗高血糖和促进肠蠕动的影响。β-内啡肽对免疫系统有重要作用,阿片-促黑素细胞皮质素原(POMC)是β-内啡肽的前体物质,为了探讨发酵乳杆菌对免疫功能的影响,检测小鼠下丘脑和脑垂体中POMC的... 详细信息

研究植物源性发酵乳杆菌对免疫系统生理活性、抗高血糖和促进肠蠕动的影响。β-内啡肽对免疫系统有重要作用,阿片-促黑素细胞皮质素原(POMC)是β-内啡肽的前体物质,为了探讨发酵乳杆菌对免疫功能的影响,检测小鼠下丘脑和脑垂体中POMC的基因表达水平。通过喂食发酵乳杆菌时间和浓度的不同及测量β-内啡肽表达水平的方式,来分析血液中β-内啡肽的变化情况。此外,测定了三种小鼠模型的血糖变化,即常规的WT小鼠模型、D-葡萄糖诱导的急性高血糖模型和链唑霉素(STZ)诱导的糖尿病模型,以证实发酵乳杆菌的降血糖效果,并对降血糖效果进行了验证。通过检测血糖随喂食发酵乳杆菌浓度和时间而变化的情况,已证实给药浓度和时间对血糖浓度有很好的影响。另外,为证实发酵乳杆菌对肠蠕动的影响测定了胃肠通过时间,证明发酵乳杆菌对肠蠕动有极好的促进作用。通过此项研究,证实发酵乳杆菌对提高人体免疫系统的生理活性、抗高血糖和促进小肠蠕动有极佳的效果。

关键词：发酵乳杆菌免疫力抗高血糖 β-内啡肽血糖肠蠕动

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使用与不使用金属伪影减低软件的双能量CT红宝石能谱成像中金属伪影减低的对照性研究

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国际医学放射学杂志 2012年第4期 406-407页

作者： Y.H. Lee K.K. park H.T. Song S. Kim J.S. suh.唐光健 Department of Radiology Research Institute of Radiological Science Medical Convergence Research Institute and Severance Biomedical Science Institute Yonsei University College of Medicine250 Seongsanno Seodaemun-gu Seoul 120-752 Republic of Korea

摘要目的评价红宝石成像（GSI）双能量CT（DECT）使用或不使用金属伪影减低软件（MARs）时的效用。方法DECT采用80kV与140kV快速切换GSI。CT数据在使用与不使用MARs的条件下,以不同视野（DFOV）与40;40kV范围集成单能回顾性重建。模型... 详细信息

摘要目的评价红宝石成像（GSI）双能量CT（DECT）使用或不使用金属伪影减低软件（MARs）时的效用。方法DECT采用80kV与140kV快速切换GSI。CT数据在使用与不使用MARs的条件下,以不同视野（DFOV）与40;40kV范围集成单能回顾性重建。模型研究采用不同大小、不同CT值的钛板与不锈钢

关键词：双能量CT CT 金属伪影

肿瘤总大小对临床ⅠA期含有部分实性结节病灶的肺腺癌病人预后的影响:仅实性部分的大小有影响吗?

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国际医学放射学杂志 2019年第3期 373-373页

作者：王志炜 H.Kim J.Goo Y.suh.C.park Y.Kim Department of Radiology Seoul National University College of Medicineand Institute of Radiation MedicineSeoul National University Medical Research Center

摘要目的探讨临床放射学变量肿瘤总大小(T)和临床T分类(cTI)对含有部分实性结节(PSN)病灶的ⅠA期(TNM)肺腺癌病人预后的影响。方法该回顾性研究经机构

关键词：肺腺癌实性结节