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Trace fossil evidences of an Early Miocene paleoseismic event and depositional regime change from the kutch(kachchh) Basin

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Journal of Palaeogeography 2024年第1期13卷 165-180页

作者： Ayush Srivastava sudipta dasgupta.k.ishanu chatterjee Mohuli Das Bombay Ichnos Research Group Department of Earth SciencesIndian Institute of Technology Bombay(lIT Bombay)PowaiMumbaiMaharashtra400076India

Unconsolidated siliciclastic sediments can undergo post-burial deformation, which leads to the formation of distinctive sedimentary structures, known as soft-sediment deformation structures(SSDS). The presence of a series of sand volcanoes confined to a particular lithostratigraphic horizon can represent a paleoseismic activity and, thereby, exemplifies the concept of “seismite”. The kutch Basin has been a tectonically active region since the initiation of eastern Gondwana rifting followed by a tectonic inversion during the Cenozoic due to the collision of the Indian and Eurasian plates. A stratum-bound series of sand volcanoes belonging to the khari Nadi Formation(kNF) is exposed along the banks of khari River. They separate the shallow marine deposits below and non-marine deposits above with their characteristic marine and paleosol trace fossil suites, respectively. Although a seismogenic origin has been much debated for the SSDS,the ichnofabric analysis of the sand-volcano-bearing stratum unequivocally points toward such an origin under a shallow seafloor condition. In addition to the sedimentary regime change from an open shallow-marine setting to a continental depositional environment concomitant with basinal uplift, the behavior of the burrowing crustaceans testifies to a syn-depositional development of a fault network associated with the fluidization, sand volcanism, and the resilience of the trace-producers in surviving those processes until the sedimentary regime change in the overlying strata. Although the ichno-sedimentological evidence apparently differs from the previous works that proposed a continuous base-level rise from the beginning of deposition of the khari Nadi Formation up to the middle part of the overlying Chhasra Formation, the paleoseismic activity,its ichnologic signature, and the depositional regime change refer to a higher-resolution(i.e., lower-order)sequence-stratigraphic change causing a short-duration regression within a longer-durat

关键词： Sand volcano Seismite Ichnology khari Nadi Formation kutch Basin kachchh Basin

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Atherosclerotic plaque classification in carotid ultrasound images using machine learning and explainable deep learning

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Intelligent Medicine 2024年第2期4卷 83-95页

作者： Soni Singh Pankaj k.Jain Neeraj Sharma Mausumi Pohit sudipta Roy School of Vocational Studies and Applied Sciences Gautam Buddha UniversityGreater NoidaUttar PradeshIndia Artificial Intelligence and Data Science Jio Institute Navi MumbaiMaharashtraIndia School of Biomedical Engineering Indian Institute of TechnologyVaranasiUttar PradeshIndia

Objective The incidence of cardiovascular diseases(CVD)is rising rapidly *** forms of CVD,such as stroke and heart attack,are more common among patients with certain *** development is a major factor underlying cardiovascular events,such as heart attack and stroke,and its early detection may prevent such *** imaging of carotid arteries is a useful method for diagnosis of atherosclerotic plaques;however,an automated method to classify atherosclerotic plaques for evaluation of early-stage CVD is ***,we propose an automated method for classification of high-risk atherosclerotic plaque ultrasound *** Five deep learning(DL)models(VGG16,ResNet-50,GoogLeNet,XceptionNet,and SqueezeNet)were used for automated classification and the results compared with those of a machine learning(ML)-based technique,involving extraction of 23 texture features from ultrasound images and classification using a Support Vector Machine *** enhance model interpretability,output gradient-weighted convolutional activation maps(GradCAMs)were generated and overlayed on original *** A series of indices,including accuracy,sensitivity,specificity,F1-score,Cohen-kappa index,and area under the curve values,were calculated to evaluate model *** output images allowed visualization of the most significant ultrasound image *** GoogLeNet model yielded the highest accuracy(98.20%).Conclusion ML models may be also suitable for applications requiring low computational ***,DL models could be more completely automated than ML models.

关键词： Explainable deep learning Carotid artery Classification VGG 16 ResNet-50 GoogLeNet XceptionNet SqueezeNet

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Computerized geochemical modeling of burial diagenesis of the Eocene turbidite reservoir elements：Urucutuca Formation,Espirito Santo Basin,southeastern Brazil passive margin

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Journal of Palaeogeography 2018年第4期7卷 363-377页

作者： Marcos Antonio klunk sudipta dasgupta Rommulo Vieira Conceicao Institute of Isotope Geology Federal University of Rio Grande do SulPorto AlegreBrazil Department of Earth Sciences Indian Institute of Technology (IIT) BombayMumbai India

The computerized geochemical modeling, a useful tool to understand the diagenetic processes influencing the quality of hydrocarbon reservoirs, is performed by using different modules of computer codes based on the thermodynamic and chemical kinetic principles and their associated parameters. As observed in the reservoir lithofacies deposited from the marine sediment-gravity flows, a case study of diagenesis is presented here from the Espírito Santo Basin in southeastern Brazil. The study uses the Geochemist＇s Workbench（GWB～（TM））, PHREEQC～（TM） and TOUGHREACT～（TM） computation packages. The comparison of performances of these packages demonstrates the convergence of results from the software-based geochemical modeling with the petrographic observation of dissolution, albitization, kaolinization, and the precipitation of calcite and dolomite. Moreover, with limited data points, e.g., the sedimentary petrographic data acquired from limited number of boreholes, the computer simulation establishes itself to be a powerful quantitative method estimating the degree and type of diagenetic alteration of turbidite reservoir bodies in contact with a source of saline-water influx associated with salt ***, using the limited petrographic data points, the geochemical computer-simulation method can even be utilized and extrapolated for areas where similar geological context is interpreted but no borehole data are available. Hence, porosity of turbidite reservoir lithofacies can be predicted in relation to the spatial distribution of dissolution, kaolinization, and albitization of feldspars and authigenic carbonate precipitation.

关键词： Sandstone diagenesis Computerized diagenetic modeling Turbidite reservoir GWB PHREEQC TOUGHREACT

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Titanate incorporated anodized coating on magnesium alloy for corrosion protection,antibacterial responses and osteogenic enhancement

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Journal of Magnesium and Alloys 2022年第4期10卷 1109-1123页

作者： Saranya.k Bhuvaneswari.S Suvro chatterjee Rajendran.N Department of Chemistry College of Engineering Guindy CampusAnna UniversityChennaiTamil Nadu 600025India Vascular Biology Lab AU-KBC Research CentreAnna UniversityChromepetChennaiTamil Nadu 600044India

The rapid degradation of Mg alloy was reduced by incorporating titanate on a fluorine-based anodized *** coating shows(i)excellent biomineralization ability,(ii)improved local and periodical corrosion behavior and(iii)enhanced expression of osteogenic factors(Runx2,Col 1,OCN and OPN)along with(iv)the antibacterial *** fluoride and magnesium ions dissolution from the anodized layer is responsible for the better expression of osteogenic factors and antibacterial *** preparation of the titanate incorporated anodized Mg alloy(Ti-AMg)is a facile solution to overcome the implant-associated bacterial infections with required biological functions including progression of bone ingrowth and biocompatibility.

关键词： AZ31 Magnesium alloy Titanate Anodization Localized electrochemical impedance spectroscopy Osteogenic factor Anti-bacterial

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Thermal history of a Late Mesoproterozoic paired metamorphic belt(?)during Rodinia assembly:New insight from medium-pressure granulites from the Aravalli-Delhi Mobile Belt, Northwestern India

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Geoscience Frontiers 2018年第2期9卷 335-354页

作者： Santanu kumar Bhowmik Somnath dasgupta sudipta Baruah Deepika kalita Department of Geology and Geophysics Indian Institute of Technology Kharagpur Department of Geography Faculty of Natural SciencesJamia Millia Islamia

In this study, we investigate the possible record of a Late Mesoproterozoic paired metamorphic belt in the Aravalli-Delhi Mobile Belt(ADMB), NW India using a suite of supracrustal and metaigneous granulites from the Pilwa-Chinwali granulite terrain at the north-western margin of the ADMB. Using metamorphic reaction textures, mineral chemistry, metamorphic reaction history, geothermobarometric computations and electron microprobe dating of monazite in 5 samples of pelitic granulite, leptynite gneiss, enderbite and charnockite, we have deduced a medium-pressure granulite facies metamorphism(P between 4.9 and 6.8 kbar, T> 760-815℃) along a heating-cooling, counterclockwise P-T path between 1.09 and 1.01 Ga. When collated with published metamorphic and chronological constraints and geological settings of the adjoining crustal domains of the ADMB, these findings provide new insights into the developments of two tectonic domains of contrasting thermal gradients at ca. 1.0 Ga, consistent with metamorphic transformations in tectonically thickened middle-lower crustal sections during continental collision to continental subduction and in the root zones of spatially adjacent island arc, as part of the Rodinia supercontinent assembly event.

关键词： ADMB Granulites CCW-P-T path Monazite chemical dating ca. 1.0 Ga metamorphism Paired metamorphic belt

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Controlled transition to different proton acceleration regimes:Near-critical-density plasmas driven by circularly polarized few-cycle pulses

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Matter and Radiation at Extremes 2023年第5期8卷 1-18页

作者： Shivani Choudhary De Marco sudipta Mondal Daniele Margarone Subhendu kahaly AFFILIATIONS 1 ELI-ALPS ELI-HU Non-Profit Ltd.Wolfgang Sandner utca 3Szeged 6728Hungary ELI Beamlines Center Institute of PhysicsCzech Academy of SciencesZa Radnicí835252-41 DolníBrezanyCzech Republic Institute of Physics University of SzegedDóm tér 9H-6720 SzegedHungary

A controlled transition between two different ion acceleration mechanisms would pave the way to achieving different ion energies and spectral features within the same experimental set up,depending on the region of *** on numerical simulations conducted over a wide range of experimentally achievable parameter space,reported here is a comprehensive investigation of the different facets of ion acceleration by relativistically intense circularly polarized laser pulses interacting with thin near-critical-density plasma *** results show that the plasma thickness,exponential density gradient,and laser frequency chirp can be controlled to switch the interaction from the transparent operating regime to the opaque one,thereby enabling the choice of a Maxwellian-like ion energy distribution with a cutoff energy in the relativistically transparent regime or a quasi-monoenergetic spectrum in the opaque ***,it is established that a multispecies target configuration can be used effectively for optimal generation of quasi-monoenergetic ion bunches of a desired ***,the feasibility is demonstrated for generating monoenergetic proton beams with energy peak atℰ≈20–40 MeV and a narrow energy spread ofΔℰ/ℰ≈18%–28.6%confined within a divergence angle of∼175 mrad at a reasonable laser peak intensity of I0≃5.4×10^(20)W/cm^(2).

关键词： acceleration regime circular

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Targeting PD-1/PD-L1 in cancer immunotherapy:An effective strategy for treatment of triple-negative breast cancer(TNBC)patients

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Genes & Diseases 2023年第4期10卷 1318-1350页

作者： Sunny kumar Mouli chatterjee Pratyasha Ghosh kirat k.Ganguly Malini Basu Mrinal k.Ghosh Cancer Biology and Inflammatory Disorder Division Council of Scientific and Industrial Research-Indian Institute of Chemical Biology(CSIR-IICB)TRUE CampusCN-6SectoreVSalt LakeKolkata 700091JadavpurKolkataPIN 700032India Department of Economics Bethune CollegeUniversity of CalcuttaKolkataPIN 700006India Department of Microbiology Michael Madhusudan Memorial CollegeDurgapurPIN 713216India Department of Microbiology Dhruba Chand Halder CollegeUniversity of CalcuttaKolkataPIN 743372India

Maintaining the balance between eliciting immune responses against foreign pro-teins and tolerating self-proteins is crucial for maintenance of *** functions of programmed death protein 1(PD-1)and its ligand programmed death ligand 1(PD-L1)are to inhibit immune responses so that over-reacting immune cells does not cause any damage to its own body ***,cancer cells hijack this mechanism to attenuate immune cells functions and create an immunosuppressive environment that fuel their continuous growth and *** the past few years’rapid development in cancer immunotherapy has opened a new avenue in cancer *** of PD-1 and PD-L1 has become a potential strategy that rescue the functions of immune cells to fight against cancer with high ***,immune checkpoint monotherapies were not very successful,making breast cancer less ***,recent reports support the presence of tumor infiltrating lympho-cytes(TILs)in breast cancer that make it favorable for PD-1/PD-L1 mediated immunotherapy,which is effective in PD-L1 positive ***,anti-PD-1(pembrolizumab)and anti-PD-L1(atezolizumab)gets FDA approval for breast cancer treatment and make PD-1/PD-L1 immunotherapy is meaningful for further ***,this article gathered understand-ing of PD-1 and PD-L1 in recent years,their signaling networks,interaction with other mole-cules,regulations of their expressions and functions in both normal and tumor tissue microenvironments are crucial to find and design therapeutic agents that block this pathway and improve the treatment ***,authors collected and highlighted most of the important clinical trial reports on monotherapy and combination therapy.

关键词： Breast cancer Cancer Clinical trial Immunotherapy PD-1/PD-L1 TNBC

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Exciton fine structure in twisted transition metal dichalcogenide heterostructures

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npj Computational Materials 2023年第1期9卷 417-423页

作者： sudipta kundu Tomer Amit H.R.krishnamurthy Manish Jain Sivan Refaely-Abramson Centre for Condensed Matter Theory Department of PhysicsIndian Institute of ScienceBangalore 560012India Department of Molecular Chemistry and Materials Science Weizmann Institute of ScienceRehovot 7610001Israel Present address:Department of Materials Science and Engineering Stanford UniversityStanfordCA 94305USA

Moirésuperlattices of transition metal dichalcogenide(TMD)heterostructures give rise to rich excitonic phenomena associated with the interlayer twist *** calculations of excitons in such systems are typically based on model moirépotentials that mitigate the computational ***,predictive understanding of the electron-hole coupling dominating the excitations is crucial to realize the twist-induced modifications of the optical selection *** this work,we use many-body perturbation theory to evaluate the relation between twist angle and exciton properties in TMD *** present an approach for unfolding excitonic states from the moiréBrillouin zone onto the separate-layer *** this method to a large-angle twisted MoS^(2)/MoSe^(2) bilayer,we find that the optical spectrum is dominated by mixed electron–hole transitions with different momenta in the separate monolayers,leading to unexpected hybridization between interlayer and intralayer *** findings offer a design pathway for exciton layer-localization in TMD heterostructures.

关键词： twisted twist transition

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Accretion flow properties of XTE J1118+480 during its 2005 outburst

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Research in Astronomy and Astrophysics 2020年第11期20卷 222-230页

作者： Dipak Debnath Debjit chatterjee Arghajit Jana Sandip k.Chakrabarti kaushik chatterjee Indian Centre for Space Physics 43 ChalantikaGaria St.Rd.Kolkata700084India Physical Research Laboratory NavrangpuraAhmedabad 380009India

We study spectral and temporal properties of Galactic short orbital period transient black hole XTE J1118+480 during its 2005 outburst using archival data of RXTE PCA and HEXTE instruments in the combined energy range of 3−100 *** analysis with the physical two component advective flow(TCAF)model allows us to understand the accretion flow properties of the *** found that this outburst of XTE J1118+480 is an unconventional outburst as the source was only in the hard state(HS).Our spectral analysis suggests that during the entire outburst,the source was highly dominated by the low angular momentum sub-keplerian halo *** the source was active in radio throughout the outburst,we make an effort to estimate X-ray contribution of jets to total observed X-ray emissions from the spectral analysis with the TCAF *** total X-ray intensity shows a similar nature of evolution as that of radio and jet X-ray *** allowed us to define this‘outburst’also as a jet dominated‘outburst’.Total X-ray flux is also found to subside when jet activity *** detailed spectral analysis also indicated that although the source was only in the HS during the outburst,in the late declining phase the spectrum became slightly softer due to the slow rise in the keplerian disk rate.

关键词： X-Rays binaries-stars black holes-stars individual (XTE J1118+480)-accretion,accretion disks-ISM jets and outflows-radiation dynamics

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Effect of coefficient of restitution in Euler-Euler CFD simulation of fluidized-bed hydrodynamics

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Particuology 2014年第4期12卷 170-177页

作者： Chanchal Loha Himadri Chattopadhyay Pradip k.chatterjee Thermal Engineering Division CSIR-Central Mechanical Engineering Research InstituteDurgapur 713209India Department of Mechanical Engineering Jadavpur UniversityKolkata 700032India

Collision between particles plays an important role in determining the hydrodynamic characteristics of gas-solid flow in a fluidized bed. In the present work, earlier work （Loha, Chattopadhyay, ＆ chatterjee, 2013） was extended to study the effect of the elasticity of particle collision on the hydrodynamic behavior of a bubbling fluidized bed filled with 530-~m particles. The Eulerian-Eulerian two-fluid model was used to simulate the hydrodynamics of the bubbling fluidized bed, where the solid-phase properties were calculated by applying the kinetic theory of granular flow. To investigate the effect of the elasticity of particle collision, different values of the coefficient of restitution were applied in the simulation and their effects were studied in detail. Simulations were performed for two different solid-phase wall boundary conditions. No bubble formation was observed for perfectly elastic collision. The bubble formation started as soon as the coefficient of restitution was set below 1.0, and the space occupied by bubbles in the bed increased with a decrease in the coefficient of restitution. Simulation results were also compared with experimental data available in the literature, and good agreement was found for coefficients of restitution of 0.95 and 0.99.

关键词： Coefficient of restitution Fluidization Hydrodynamics Computational fluid dynamics Euler-Euler approach

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