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Impact of single chamber and dual chamber permanent pacemaker implantation on left ventricular function:An observational study

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World Journal of Cardiology 2024年第11期16卷 644-650页

作者： Merajul Haque Monika Bhandari Akshyaya Pradhan Pravesh Vishwakarma Abhishek Singh Ayush Shukla Akhil Sharma Gaurav Chaudhary Rishi Sethi Sharad Chandra Arvind Jaiswal sudhanshu kumar dwivedi Department of Cardiology BRD Medical CollegeGorakhpur 273013Uttar PradeshIndia Department of Cardiology King George’s Medical UniversityLucknow 226003Uttar PradeshIndia

BACKGROUND Permanent pacemaker implantation has the potential to impact left ventricular(LV)function and hence quality of life(QoL)in the long *** To assess the effect of single-and dual-chamber pacing on LV function and *** This study included 56 patients who underwent permanent pacing:Dual pacing,dual sensing,dual responsive and rate responsive(DDDR)for the initial 3 months,ventricular sensing,inhibited response and rate responsive(VVIR)for the next 3 months,and DDDR mode for the last 3 *** the study period,various echocardiographic parameters,functional status,and QoL were measured to assess the impact of pacing on LV function compared with baseline and at every 3 months *** A significant change appeared in cardiac function after VVIR pacing which was in diastolic properties of LV as shown by increase in isovolumic relaxation time from(85.28±9.54 ms)to(89.53±9.65 ms).At the 3-,6-,and 9-month follow-up,reduction in LV ejection fraction was observed to be 62.71±4.66%,61.07±4.41%,and 58.48±3.89%,*** increase in the QoL scores was noted at every follow-up *** An apparent depressant effect on LV function due to right ventricular pacing,with a higher incidence of adverse outcomes in the VVIR *** addition,an upsurge in QoL scores for the study population was noted,which indicates improvement in the QoL of patients post-pacing,irrespective of the ***,the DDDR mode is a highly preferable pacing mode.

关键词： Artificial pacemaker Echocardiography Left ventricular function Quality of life

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Feasibility and efficacy of delayed pharmacoinvasive therapy for STelevation myocardial infarction

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World Journal of Cardiology 2023年第1期15卷 23-32页

作者： Rishi Sethi Lalit Mohan Pravesh Vishwakarma Abhishek Singh Swati Sharma Monika Bhandari Ayush Shukla Akhil Sharma Gaurav Chaudhary Akshyaya Pradhan Sharad Chandra Varun Shankar Narain sudhanshu kumar dwivedi Department of Cardiology King George's Medical UniversityLucknow 226003Uttar PradeshIndia

BACKGROUND ST-elevation myocardial infarction(STEMI)refers to a clinical syndrome that features symptoms of myocardial ischemia with consequent ST-elevation on electrocardiography and an associated rise in cardiac *** restoration of brisk flow in the coronary vasculature is critical in reducing mortality and *** patients with STEMI who could not receive primary percutaneous coronary intervention(PCI)on time,pharmacoinvasive strategy(thrombolysis followed by timely PCI within 3-24 h of its initiation)is an effective *** To analyze the role of delayed pharmacoinvasive strategy in the window period of 24-72 h after *** This was a physician-initiated,single-center prospective registry between January 2017 and July 2017 which enrolled 337 acute STEMI patients with partially occluded coronary *** received routine pharmacoinvasive therapy(PCI within 3-24 h of thrombolysis)in one group and delayed pharmacoinvasive therapy(PCI within 24-72 h of thrombolysis)in another *** primary endpoint was major adverse cardiac and cerebrovascular events(MACCE)within 30 d of the *** secondary endpoints included major bleeding as defined by Bleeding Academic Research Consortium classification,angina,and dyspnea within 30 *** The mean age in the two groups was comparable(55.1±10.1 years vs 54.2±10.5 years,P=0.426).Diabetes was present among 20.2%and 22.1%of patients in the routine and delayed groups,*** rate was 54.6%and 55.8%in the routine and delayed groups,*** was initiated within 6 h of onset of symptoms in both groups(P=0.125).The mean time from thrombolysis to PCI in the routine and delayed groups was 16.9±5.3 h and 44.1±14.7 h,*** significant difference was found for the occurrence of measured clinical outcomes in the two groups within 30 d(8.7%vs 12.9%,P=0.152).Univariate analysis of demographic characteristics and risk factors for patients who reporte

关键词： Coronary artery disease ST-elevation myocardial infarction Primary percutaneous coronary intervention Pharmacoinvasive strategy Thrombolysis Atherosclerosis

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Graphene sandwiched crumb rubber dispersed hot mix asphalt

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第5期7卷 652-667页

作者： Bineet Baliyar Singh Fanismita Mohanty sudhanshu Sekhar Das Sarat kumar Siuain Department of Civil Engineering Veer Surendra Sai University of TechnologyBurla 768018India Department of Chemistry Veer Surendra Sai University of TechnologyBurla 768018India

The crumb rubber obtained from discarded vehicle tires and graphene oxide prepared by oxidation of graphite powder in laboratory were used to modify virgin bitumen. Four different hot mix asphalt matrices prepared using virgin bitumen, crumb rubber modified bitumen, graphene oxide modified bitumen and combination of crumb rubber-graphene oxide modified bitumen are compared. The modified bitumen matrices are characterised by Fourier transform infrared spectroscopy and scanning electron microscopy for structural and morphological analysis. Marshall properties along with indirect tensile test and tensile strength ratio tests were carried out to check the resistance towards cracking and moisture susceptibility of matrices. The results show that, crumb rubber and graphene oxide are completely compatible with bitumen. 9.8% crumb rubber content in crumb rubber modified bitumen hot mix asphalt exhibits the optimum result. The performance of graphene oxide modified bitumen hot mix asphalt exhibits superior performance in comparison to control mix and crumb rubber modified bitumen hot mix asphalt *** enhanced properties of modified bitumen hot mix asphalt with the combining effect of graphene oxide and crumb rubber, are suitable for road construction.

关键词： Hot mix asphalt Crumb rubber Graphene oxide Modified bitumen

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Mathematical model of zika virus dynamics with vector control and sensitivity analysis

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Infectious Disease Modelling 2020年第1期5卷 23-41页

作者： sudhanshu kumar Biswas Uttam Ghosh Susmita Sarkar Department of Mathematics Sripat Singh CollegeMurshidabadWest BengalIndia Department of Applied Mathematics University of CalcuttaKolkataIndia

In this paper,we have developed and analyzed a deterministic Zika model considering both vector and sexual transmission route with the effect of human awareness and vector control in the absence of disease induce *** formulate the model,we assume that the Zika virus is being first transmitted to human by mosquito bite,and then it is being transmitted to his or her sexual *** system contains at most three equilibrium points among them one is the disease free and other two are endemic equilibrium points,exists under certain *** theoretical analysis shows that the diseases-free equilibrium is locally and globally asymptotically stable if the basic reproduction number is less than *** we have established that endemic equilibrium point which is locally asymptotically stable if the basic reproduction number is greater than *** system exhibits backward bifurcation when the transmission probability per biting of susceptible mosquito with infected humans crosses the critical *** estimate the model parameters and validate the model by fitting the model with the reported Zika infected human data from 1 to 36 week of 2016 Zika outbreak in ***,using the normalised forward sensitivity index method we have established that the model parameter mosquito biting rate,recruitment rate of mosquito,transmission probability per biting of Susceptible(infected)humans with infected(susceptible)mosquito,rate of awareness in host population,recovery rates of infected human are most sensitive parameters of the considered Zika ***,some conclusions are given to control the spreading of the Zika disease.

关键词： Zika virus Vector transmission Sexual transmission Basic reproduction number Stability analysis Backward bifurcation Sensitivity analysis

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Removal of Fluoride from Groundwater by Carbonised <i>Punica granatum</i>Carbon (“CPGC”) Bio-Adsorbent

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Journal of Geoscience and Environment Protection 2015年第4期3卷 1-9页

作者： sudhanshu Kanaujia Bharat Singh Sanjay kumar Singh Department of Chemistry United College of Engineering and Research Allahabad India Department of Chemistry University of Allahabad Allahabad India Department of Chemistry Institute of Engineering and Technology Lucknow India

This study applies the development and application of low cost, Punica granatum bio-adsorbent for the removal of fluoride in groundwater. The batch adsorption study was carried out to analyze the defluoridation by contact time variation, adsorbent dose, adsorbate concentration, adsorbent particle size and presence of co-anions at neutral pH. The analysis of the isotherm equilibrium data using the Langmuir and Freundlich equations by linear methods showed that the data fitted better with Freundlich model (R2 > 0.980). Prepared adsorbent showed enhanced removal of fluoride concentration by 78.1% at equilibrium contact time of 75 minutes. Carbonised Punica granatum Carbon (CPGC) seeds showed a high affinity for fluoride ions compared with other conventional adsorbents. Therefore, it can be considered as a potentially “good”, low-cost bio-adsorbent for de-fluoridation of water compared to other bio-adsorbent.

关键词： Fluoride Removal Adsorption Punica granatum Bio-Adsorbent

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Sensitivity of Nanostructured Iron Metal on Ultrasonic Properties

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Open Journal of Metal 2011年第2期1卷 34-40页

作者： Alok kumar Gupta Archana Gupta Devraj Singh sudhanshu Tripathi 不详

The present investigation is focused on the influence of the nanocrystalline structure of pure iron metal on the ultrasonic properties in the temperature range 100 - 300 K. The ultrasonic attenuation due to phonon- phonon interaction and thermoelastic relaxation phenomena has been evaluated for longitudinal and shear waves along , and crystallographic directions. The second-and third-order elastic constants, ultrasonic velocities, thermal relaxation, anisotropy and acoustic coupling constants were also com- puted for the evaluation of ultrasonic attenuation in this temperature scale. The direction is most ap- propriate to study longitudinal sound waves, while , direction are best to propagate shear waves due to lowest values of attenuation in these directions. Other physical properties correlated with obtained results have been discussed.

关键词： Iron Metal Elastic properties Ultrasonic Attenuation

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Selective Cluster-Based Temperature Monitoring System for Homogeneous Wireless Sensor Networks

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ZTE Communications 2014年第3期12卷 22-29页

作者： sudhanshu Tyagi Sudeep Tanwar Sumit kumar Gupta Neeraj kumar Joel J.P.C.Rodrigues Department of Electronics and Communication Engineering J. P. Institute of Enginerring and Technology (JPIET) Department of Information Technology Bharat Institute of Technology Department of Electronics and Communication Engineering Institute of Information & Management Technology (IIMT) Department of Computer Science and Engineering Thapar University Instituto de Telecomunicaōes University of Beira Interior University ITMO

Over the past few decades, there has been a revolution in ICT, and this has led to the evolution of wireless sensor networks （WSN）, in particular, wireless body area networks. Such networks comprise a specialized collection of sensor nodes （SNs） that may be deployed randomly in a body area network to collect data from the human body. In a health monitoring system, it may be es-sential to maintain constant environmental conditions within a specific area in the hospital. In this paper, we propose a tempera-ture-monitoring system and describe a case study of a health-monitoring system for patents critically ill with the same disease and in the same environment. We propose Enhanced LEACH Selective Cluster （E-LEACH-SC） routing protocol for monitoring the tem-perature of an area in a hospital. We modified existing Selective Cluster LEACH protocol by using a fixed-distance-based thresh-old to divide the coverage region in two subregions. Direct data transmission and selective cluster-based data transmission ap-proaches were used to provide short-range and long-distance coverage for the collection of data from the body of ill patients. Ex-tensive simulations were run by varying the ratio of node densities of the two subregions in the health-monitoring system. Last Node Alive （LNA）, which is a measure of network lifespan, was the parameter for evaluating the performance of the proposed scheme. The simulation results show that the proposed scheme significantly increases network lifespan compared with traditional LEACH and LEACH-SC protocols, which by themselves improve the overall performance of the health-monitoring system.

关键词： network lifespan sensor node LEACH LNA

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Characterization and Evaluation of Antibacterial Activities of Chemically Synthesized Iron Oxide Nanoparticles

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World Journal of Nano Science and Engineering 2012年第4期2卷 196-200页

作者： sudhanshu Shekhar Behera Jayanta kumar Patra Krishna Pramanik Niladri Panda Hrudayanath Thatoi Department of Biotechnology and Medical Engineering National Institute of Technology Rourkela India Department of Biotechnology College of Engineering and Technology Biju Patnaik University of Technology Bhubaneswar India

The iron oxide nanoparticles have been synthesized in co-precipitation method using aqueous solution of ferric and ferrous ions with sodium salt. The synthesis of iron-oxide nanoparticles were validated by UV-Visible spectroscopy which showed higher peak at 370 nm as valid standard reference. An average size of iron oxide nanoparticle found by Diffraction Light scattering (DLS) particle size analyser, ranges approximately between 10 nm to 120 nm with mean particle size of 66 nm. The X-ray power diffraction (XRD) analysis revealed the crystallographic structure of magnetic particles. Characterization of the mean particle size and morphology of iron oxide nanoparticles confirmed that the iron oxide nanoparticles are nearly spherical and crystalline in shape. Further the antibacterial effect of iron oxide nanoparticles was evaluated against ten pathogenic bacteria which showed that the nanoparticles have moderate antibacterial activity against both Gram positive and Gram negative pathogenic bacterial strains and retains potential application in pharmaceutical and biomedical industries.

关键词： Iron Oxide Co-Precipitation Nanoparticles Antibacterial Activity

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Contamination of Lead and Mercury in Coal Basin of India

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Journal of Environmental Protection 2015年第12期6卷 1430-1441页

作者： Reetu Sharma Shobhana Ramteke Khageshwar Singh Patel sudhanshu kumar Bighnaraj Sarangi Shankar Gopal Agrawal Lesia Lata Huber Milosh School of Studies in Chemistry/Environmental Science Pt. Ravishankar Shukla University Raipur India Analytical Chemistry Section CSIR-National Physical Laboratory New Delhi India Department of Soil Science/Geology Maria Curie-Sklodowska University Lublin Poland

The coal is contaminated with toxic metals at the trace levels. They are released into the environment during mining, handling and burning of coal. The Korba basin has one of the largest coal exploitation areas in the country. In this work, contamination and sources of toxic metals i.e. Hg and Pb in the air, soil and sediment of the Korba basin, India are described. The concentration of Hg and Pb in the ambient air was ranged from 7.4 - 29 and 7.0 - 585 ng/m3 with mean value of 18 ± 4 and 129 ± 104 ng/m3 in the winter season. The mean concentration of Hg in the soil and sediment was 0.22 ± 0.03 and 0.44 ± 0.08 mg/kg, respectively. The higher concentration of Pb in the environmental samples was observed.

关键词： Lead Mercury Aerosol Soil Sediment

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