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Significant increase in HBV, HCV, HIV and syphilis infections among blood donors in West Bengal, Eastern India 2004-2005: Exploratory screening reveals high frequency of occult HBV infection

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World Journal of Gastroenterology 2007年第27期13卷 3730-3733页

作者： Prasun Bhattacharya Partha kumar Chandra Sibnarayan Datta Arup Banerjee Subhashish Chakraborty Krishnan Rajendran subir kumar basu Sujit kumar Bhattacharya Runu Chakravarty Institute of Blood Transfusion Medicine and Immunohematology Kolkata India ICMR Virus Unit Kolkata India National Institute of Cholera and Enteric Diseases Kolkata India

AIM: To evaluate the prevalence of markers of hepatitis B virus (HBV) and hepatitis C virus (HCV) and human immunodeficiency virus (HIV) among blood donors in Kolkata, Eastern India for two consecutive years and to conduct a pilot study to explore the presence of HBV DNA among hepatitis B surface antigen (HBsAg) negative but anti-HBc positive blood donors. METHODS: Seroprevalence of HBsAg, anti-HCV and anti-HIV was studied among 113 051 and 106 695 voluntary blood donors screened in 2004 and 2005, respectively. Moreover, a pilot study on 1027 HBsAg negative donors was carried out for evaluating the presence of HBV DNA by PCR on HBsAg negative/anti- HBc positive donors. RESULTS: A statistically significant increase in the prevalence of HBV (1448 vs 1768, P < 0.001), HIV (262 vs 374, P < 0.001), HCV (314 vs 372, P = 0.003) and syphilis (772 vs 853, P = 0.001) infections was noted among blood donors of Kolkata West Bengal in 2005 as compared to 2004. Moreover, the exploratory study on 1027 HBsAg negative donors revealed that 188 (18.3%)of them were anti-HBc positive out of which 21% were positive for HBV DNA. CONCLUSION: The findings of this study underscore the significantly increasing endemicity of hepatitis viruses, syphilis and HIV among the voluntary blood donors of our community. The pilot study indicates a high rate of prevalence of HBV DNA among HBsAg negative/anti-HBc positive donors and thus emphasizes the need for a more sensitive and stringent screening algorithm for blood donations.

关键词： Hepatitis B virus Human immunodeficiency virus Hepatitis C virus Blood donation Occult HBV infection

Novel insights on oral squamous cell carcinoma management using long non-coding RNAs

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Oncology Research 2024年第10期32卷 1589-1612页

作者： SUBHAYAN SUR DIMPLE DAVRAY SOUMYA basu SUPRIYA KHEUR JAYANTA kumar PAL SHUCHI NAGAR AVINASH SANAP BHIMAPPA MRUDAGI SAMIR GUPTA Cancer and Translational Research Centre Dr.D.Y.Patil Biotechnology and Bioinformatics InstituteDr.D.Y.Patil VidyapeethTathawadePune411033India Bioinformatics Centre Dr.D.Y.Patil Biotechnology and Bioinformatics InstituteDr.D.Y.Patil VidyapeethPune411033India Department of Oral Pathology and Microbiology Dr.D.Y.Patil Dental College&HospitalDr.D.Y.Patil VidyapeethPune411018India Department of Surgical Oncology Dr.D.Y.Patil Medical CollegeHospital&Research CentreDr.D.Y.Patil VidyapeethPune411018India

Oral squamous cell carcinoma(OSCC)is one of the most prevalent forms of head and neck squamous cell carcinomas(HNSCC)with a poor overall survival rate(about 50%),particularly in cases of ***-based cancer biomarkers are a relatively advanced concept,and non-coding RNAs currently have shown promising roles in the detection and treatment of various *** review underlines the function of long non-coding RNAs(lncRNAs)in the OSCC and its subsequent clinical ***,a class of non-coding RNAs,are larger than 200 nucleotides and resemble mRNA in numerous ***,unlike mRNA,lncRNA regulates multiple druggable and non-druggable signaling molecules through simultaneous interaction with DNA,RNA,proteins,or microRNAs depending on concentration and localization in *** of oncogenic lncRNAs and downregulation of tumor suppressor lncRNAs are evident in OSCC tissues and body fluids such as blood and saliva indicating their potential as valuable *** inhibition of candidate oncogenic lncRNAs or overexpression of tumor suppressor lncRNAs showed potential therapeutic roles in in-vivo animal *** types of lncRNAs that are expressed differentially in OSCC tissue and bodily fluids have been systematically documented with specificity and *** review thoroughly discusses the biological functions of such lncRNAs in OSCC cell survival,proliferation,invasion,migration,metastasis,angiogenesis,metabolism,epigenetic modification,tumor immune microenvironment,and drug ***,we addressed the diagnostic and therapeutic importance of lncRNAs in OSCC pre-clinical and clinical systems,providing details on ongoing research and outlining potential future directions for advancements in this *** essence,this review could be a valuable resource by offering comprehensive and current insights into lncRNAs in OSCC for researchers in fundamental and clinical domains.

关键词： Oral squamous cell carcinoma(OSCC) Head and neck cancer Non-coding RNA Long non-coding RNA(lncRNA) Cancer diagnosis

Synthesis and characterization of ZnO-Al_2O_3 oxides as energetic electro-catalytic material for glucose fuel cell

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燃料化学学报 2015年第8期43卷 1004-1010页

作者： Sujit kumar Guchhait subir Paul Metallurgical and Material Engineering Department Jadavpur University

One of the thrust areas of research is to find an alternative fuel to meet the increasing demand for *** is a good source of alternative fuel for clean energy and is easily available in abundance from both naturally occurring plants and industrial *** oxidation of glucose in fuel cell requires high electro-catalytic surface of the electrode to produce the clean electrical energy w ith minimum energy losses in the *** and Pt based alloys exhibit high electro-catalytic properties but they are *** energy synthesis at economically cheap price,non Pt based inexpensive high electro catalytic material is *** synthesized Zn O-Al2O3composite is found to exhibit high electro-catalytic properties for glucose *** Cyclic Voltammetry and Chronoamperometry curves reflect that the material is very much comparable to Pt as far as the maximum current and the steady state current delivered from the glucose oxidation are *** image confirms the mixed oxide *** images morphology show increased 3D surface areas at higher *** attributed high current delivered from electrochemical oxidation of glucose on this electrode surface.

关键词： glucose energy materials electro-catalyst cyclic voltammetry chronoamperometry polarization

Control of Non-Deterministic Systems With μ-Calculus Specifications Using Quotienting

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IEEE/CAA Journal of Automatica Sinica 2021年第5期8卷 953-970页

作者： Samik basu Ratnesh kumar the Department of Computer Science Iowa State UniversityIowa 50011-3060 USA the Department of Electrical and Computer Engineering Iowa State UniversityIowa 50011-3060 USA

The supervisory control problem for discrete event system(DES) under control involves identifying the supervisor, if one exists, which, when synchronously composed with the DES,results in a system that conforms to the control specification. In this context, we consider a non-deterministic DES under complete observation and control specification expressed in action-based propositional μ-calculus. The key to our solution is the process of quotienting the control specification against the plan resulting in a new μ-calculus formula such that a model for the formula is the supervisor. Thus the task of control synthesis is reduced a problem of μ-calculus satisfiability. In contrast to the existing μ-calculus quotienting-based techniques that are developed in deterministic setting, our quotienting rules can handle nondeterminism in the plant models. Another distinguishing feature of our technique is that while existing techniques use a separate μ-calculus formula to describe the controllability constraint(that uncontrollable events of plants are never disabled by a supervisor), we absorb this constraint as part of quotienting which allows us to directly capture more general state-dependent controllability constraints. Finally, we develop a tableau-based technique for verifying satisfiability of quotiented formula and model generation. The runtime for the technique is exponential in terms of the size of the plan and the control specification. A better complexity result that is polynomial to plant size and exponential to specification size is obtained when the controllability property is state-independent. A prototype implementation in a tabled logic programming language as well as some experimental results are presented.

关键词： Discrete event systems(DES) non-deterministic plant μ-calculus supervisory control

Transition metal-based single-atom catalysts(TM-SACs);rising materials for electrochemical CO_(2) reduction

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Journal of Energy Chemistry 2022年第7期31卷 444-471,I0012页

作者： Bishnupad Mohanty Suddhasatwa basu Bikash kumar Jena Materials Chemistry Department CSIR-Institute of Minerals and Materials TechnologyBhubaneswar 751013India Academy of Scientific&Innovative Research(AcSIR) Ghaziabad 201002India

The continuous increase of global atmospheric CO_(2) concentrations brutally damages our environment. A series of methods have been developed to convert CO_(2) to valuable fuels and value-added chemicals to maintain the equilibrium of carbon cycles. The electrochemical CO_(2) reduction reaction(CO_(2)RR) is one of the promising methods to produce fuels and chemicals, and it could offer sustainable paths to decrease carbon intensity and support renewable energy. Thus, significant research efforts and highly efficient catalysts are essential for converting CO_(2) into other valuable chemicals and fuels. Transition metal-based single atoms catalysts(TM-SACs) have recently received much attention and offer outstanding electrochemical applications with high activity and selectivity opportunities. By taking advantage of both heterogeneous and homogeneous catalysts, TM-SACs are the new rising star for electrochemical conversion of CO_(2) to the value-added product with high selectivity. In recent years, enormous research effort has been made to synthesize different TM-SACs with different M–Nxsites and study the electrochemical conversion of CO_(2) to CO. This review has discussed the development and characterization of different TMSACs with various catalytic sites, fundamental understanding of the electrochemical process in CO_(2) RR,intrinsic catalytic activity, and molecular strategics of SACs responsible for CO_(2)RR. Furthermore, we extensively review previous studies on 1 st-row transition metals TM-SACs(Ni, Co, Fe, Cu, Zn, Sn) and dual-atom catalysts(DACs) utilized for electrochemical CO_(2) conversions and highlight the opportunities and challenges.

关键词： CO_(2)RR Single-atom catalyst SACs Dual-atom catalyst DACs Transition metals Support catalysts

A comprehensive review on phytopharmacological investigations of Acacia auriculiformis ***. ex Benth

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Asian Pacific Journal of Tropical Biomedicine 2019年第1期9卷 1-11页

作者： Naresh kumar Rangra subir Samanta Kishanta kumar Pradhan Department of Pharmaceutical Sciences & Technology Birla Institute of Technology

Acacia auriculiformis ***. ex Benth. is a perennial shrub having a wide range of medicinal potentials and is widely distributed throughout the world. It is being used traditionally to overcome various medical complications like sore eyes, aches, rheumatism, allergy, itching, and rashes. Besides, Acacia auriculiformis has been proven for many pharmacological activities like central nervous system depressant activity, antioxidant, antimicrobial, antimalarial, anti-filarial, cestocidal, antimutagenic, chemopreventive, spermicidal, wound healing, hepatoprotective and antidiabetic activity due to its low toxicity(LD50 = 3 741.7 mg/kg) and high efficacy. In addition, various phytochemical investigations reveal the presence of chief constituents as flavonoids(Auriculoside) and triterpenoid saponin glycosides(acaciasides-acaciaside A & B) in different parts of this plant. Since many years researchers have been carrying out various studies on this medicinal important shrub to elicit the various biological activities. This review attempts to highlight the pharmacognostical, phytochemical and pharmacological observations from 1965 to 2018 retrieved from SciF inder, Scientific journals, books, Google Scholar, and botanical electronic database websites. The various plant extracts evaluated for different pharmacological activities showed significant efficacy. Bioactive phytoconstituents isolated from various parts of the plant are highlighted. Pharmacognostical standardization of the plant done with various standard parameters is also reported. The low toxicity of this plant and the presence of major bioactive phytoconstituents like flavonoids and triterpenoid saponin glycosides are responsible for a therapeutic remedy for various diseases and pharmacological activities respectively. This review provides exhaustive information about the pharmacognostical, phytochemical, and pharmacological investigations of Acacia auriculiformis till date.

关键词： Acacia auriculiformis Pharmacognostical Phytochemical Pharmacological

Broadband, High Gain, Narrow Width Rectangular Dielectric Resonator Antenna with Air Gap

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Journal of Electronic Science and Technology 2019年第1期17卷 90-96页

作者： Ankit kumar Roy Sukla basu Kalyani Government Engineering College

The broadband, narrow width, rectangular dielectric resonator antenna(RDRA) of aluminum nitride(εr=8.6) was designed and the effect of inclusion of air gap at the bottom of the dielectric resonator antenna(DRA),above the ground plane, was investigated. Gain around 7 dBi was obtained for DRA with air gap(DRAAG) over a broad bandwidth in upper X, Ku, and K bands. Further enhancement in gain could be obtained by placing a metal wall parallel to the length of DRA. However, due to the presence of metal wall, bandwidth was reduced. These structures with the metal wall are capable of operating over a wide band extending from Ku band to lower K band with the gain of around 10 dBi. CST Microwave Studio Software was used to simulate all these *** parameters of DRA with air gap were compared with several broadband DRA structures reported in recent literature. The proposed DRAAG with the metal wall in this paper is capable of operating over a wide bandwidth along with a significant gain.

关键词： Dielectric resonator antenna(DRA) rectangular dielectric resonator antenna(RDRA) wide band dielectric resonator antenna X Ku and K bands dielectric resonator antenna

The evolution of graphene-based electronic devices

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International Journal of Smart and Nano Materials 2010年第3期1卷 201-223页

作者： Joydeep basu Jayanta kumar basu Tarun Kanti Bhattacharyya Department of Electronics and Electrical Communication Engineering Department of Chemical Engineering Indian Institute of TechnologyKharagpur 721302India

Successful isolation of single-layer graphene,the two-dimensional allotrope of carbon from graphite,has fuelled a lot of interest in exploring the feasibility of using it for fabrication of various electronic devices,particularly because of its exceptional electronic *** is poised to save Moore’s law by acting as a successor of silicon-based *** article reviews the success story of this allotrope with a focus on the structure,properties and preparation of graphene as well as its various device applications.

关键词： electronic device FET field effect graphene nanoelectronics

A two-dimensional analytical-model-based comparative threshold performance analysis of SOI-SON MOSFETs

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Journal of Semiconductors 2011年第10期32卷 32-38页

作者： Sanjoy Deb Saptarsi Ghosh N Basanta Singh A K De subir kumar Sarkar Department of Electronics&Telecommunication Engineering Jadavpur University Department of Electronics&Communication Engineering Manipur Institute of Technology Department of Electronics&Communication Engineering National Institute of Technology

A generalized threshold voltage model based on two-dimensional Poisson analysis has been developed for SOI/SON *** short channel field effects,such as fringing fields,junction-induced lateral fields and substrate fields,are carefully investigated,and the related drain-induced barrier-lowering effects are incorporated in the analytical threshold voltage *** analytical model-based simulation,the threshold voltage roll-off and subthreshold slope for both structures are compared for different operational and structural parameter *** of analytical simulation are compared with the results of the ATLAS 2D physics-based simulator for verification of the analytical *** performance of an SON MOSFET is found to be significantly different from a conventional SOI *** short channel effects are found to be reduced in an SON,thereby resulting in a lower threshold voltage roll-off and a smaller subthreshold *** type of analysis is quite useful to figure out the performance improvement of SON over SOI structures for next generation short channel MOS devices.

关键词： silicon-on-insulator silicon-on-nothing Poisson's equation short channel effects threshold voltage roll-off subthreshold slope