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Lubiprostone induced ischemic colitis

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World Journal of Gastroenterology 2013年第2期19卷 299-303页

作者： Muhammed Sherid Humberto Sifuentes Salih Samo Parakkal Deepak subbaramiah sridhar Department of Internal Medicine Division of GastroenterologySaint Francis HospitalEvanstonIL 60202United States Section of Gastroenterology and Hepatology Medical College of GeorgiaGeorgia Health Sciences UniversityAugustaGA 30912United States Department of Internal Medicine Division of GastroenterologyNorthShore University HealthSystemHighland ParkIL 60035United States

Ischemic colitis accounts for 6%-18% of the causes of acute lower gastrointestinal *** is often multifactorial and more commonly encountered in the *** medications have been implicated in the development of colonic *** report a case of a 54-year old woman who presented with a two-hour history of nausea,vomiting,abdominal pain,and bloody *** patient had recently used lubiprostone with close temporal relationship between the increase in the dose and her symptoms of rectal *** radiologic,colonoscopic and histopathologic findings were all consistent with ischemic *** condition improved without any serious complications after the cessation of *** is the first reported case of ischemic colitis with a clear relationship with lubiprostone(Naranjo score of 10).Clinical vigilance for ischemic colitis is recommended for patients receiving lubiprostone who are presenting with abdominal pain and rectal bleeding.

关键词： Lubiprostone Ischemic colitis Gastrointestinal bleeding Rectal bleeding Colonoscopy

Eosinophilic ascites,an unusual presentation of eosinophilic gastroenteritis:A case report and review

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World Journal of Gastrointestinal Pathophysiology 2010年第5期1卷 166-170页

作者： Iryna S Hepburn subbaramiah sridhar Robert R Schade Section of Gastroenterology and Hepatology Department of Me-dicineMedical College of Georgia

Eosinophilic ascites(EA)is a rare disorder of unknown etiology that has been reported in both adult and pediatric *** is a part of the syndrome of eosinophilic gastroenteritis,which is characterized by eosinophilic infiltration of any or all layers of the gut wall and may involve any segment of the gastrointestinal *** eosinophilia may or may not be *** report a case of EA that developed post partum.

关键词： Ascites Eosinophilia Pregnancy

A nano-plasmonic HMIM waveguide based concurrent dual-band BPF using circular ring resonator

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Optoelectronics Letters 2024年第3期20卷 152-156页

作者： Miriyala sridhar Surendra Kumar Bitra TS N Murthy Koppireddi Padmaraju Department of Electronics and Communication Engineering Koneru Lakshmaiah Education FoundationGunturIndia Astra Microwave Products Ltd. HyderabadIndia Department of Electronics and Communication Engineering JNTU-GV College of EngineeringVizianagaramIndia Department of Electronics and Communication Engineering Jawaharlal Nehru Technological University KakinadaKakinadaIndia

This article analyzes the transmission line characteristics of plasmonic hybrid metal insulator metal(HMIM) wave-guide, circular ring resonator(CRR) based dual-band band-pass filters with two transmission poles in both pass-bands in the optical regime using coupled line feed. The transmission line characteristics of an HMIM waveguide, such as characteristic impedance(Z_(PV)), effective refractive index(n_(eff)) and propagation length(L_(spp)), have been obtained by using full wave simulation.

关键词： waveguide resonator circular

Lubiprostone used with polyethylene glycol in diabetic patients enhances colonoscopy preparation quality

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World Journal of Gastrointestinal Endoscopy 2010年第7期2卷 263-267页

作者： Erika Grigg Moonkyung C Schubert Joshua Hall Fadi Rahhal Dimple Raina subbaramiah sridhar Sherman M Chamberlain Section of Gastroenterology and Hepatology Medical College of GeorgiaAugustaGA 30912United States

AIM: To assess the additive effect of lubiprostone on the quality of colon preparation in diabetics given single-dosed polyethylene glycol electrolyte(PEG)for ***:This was an investigator-initiated,singlecenter,single-blinded prospective trial comparing the efficacy of L+PEG to PEG alone on colon preparation quality in diabetics undergoing screening *** study was approved by our institution’s *** PEG was given as a single-dose to address patientcompliance concerns voiced by our IRB with *** patients received only clear liquids the day prior to *** group(Grp L)received PEG+1 dose L 2 h prior to and 2 h after PEG *** group(Grp C)received only PEG the evening prior to the *** were randomly assigned to one of the 2 *** endoscopist was blinded to which colon prep was given and all colonoscopies were *** colonoscopy completion,the endoscopist rated the colon prep-quality by a validated 5-point Likert scale(1-excellent to 5-inadequate).RESULTS:Sixty patients were enrolled in the study;30 Grp L and 30 Grp ***,patients were excluded due to study non-completion in 12(41%)Grp L and 5(17%) Grp C,P=*** colon preparation score Grp L =2.47 and Grp C=3.00,P=*** this was not statistically significant,there was a trend towards improved colon prep in Grp *** significance may have been achieved if completion rates had been similar between both study ***:Use of 2-L capsules with PEG resulted in a trend towards improved colon prep over PEG alone in diabetic patients when given as a single-dose regimen.

关键词： Lubiprostone Polyethylene glycol Diabetes Colonoscopy colon preparation

Empirical model for fusion cross sections of Ca-induced reactions

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Chinese Physics C 2024年第3期48卷 126-132页

作者： Reddi Rani.L N.Sowmya K.N sridhar H C.Manjunatha M.M.Armstrong Arasu Department of Physics St.Joseph's College(Autonomous)Affiliated to Bharathidasan UniversityTiruchirappalli620002TNIndia Department of Physics Govt.First.Grade CollegeChikkaballapur-562101KarnatakaIndia Department of Physics Govt.First.Grade CollegeMalur-563160KarnatakaIndia Department of Physics Govt.First.Grade CollegeDevanahalli-562110KarnatakaIndia

A new empirical formula for the astrophysical S-factor has been suggested as a function of the Coulomb interaction parameter,center of mass energy,and barrier *** 22 fusion reactions with ^(40,48)Ca as projectiles were considered for different targets,leading to compound nuclei with atomic and mass numbers varying between 40≤Z≤≤Z≤112 and 88≤A≤27888≤A≤278,*** fusion cross-sections have been estimated using the geometric factor,the Gamow-Sommerfield factor,and the empirical formula for the *** study's findings showed better agreement with those of available experiments when compared to Wong's *** present work leads to a smaller standard deviation value than Wong's formula when used to correlate the experimental data of calcium-induced fusion ***'s formula provides a good approximation of fusion cross-sections when the center of mass energy is below the fusion barrier when compared to above the fusion barrier.

关键词： fusion cross-sections Wong formula Gamow-Sommerfield-factor Geometric-factor S-factor

Built environment and childhood obesity

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World Journal of Clinical Pediatrics 2024年第3期13卷 11-21页

作者： Gumpeny R sridhar Lakshmi Gumpeny Department of Endocrinology and Diabetes Endocrine and Diabetes CentreVisakhapatnam 530002Andhra PradeshIndia Department of Internal Medicine Gayatri Vidya Parishad Institute of Healthcare and Medical TechnologyVisakhapatnam 530048Andhra PradeshIndia

Childhood obesity,an escalating global health challenge,is intricately linked to the built environment in which children live,learn,and *** review and perspective examined the multifaceted relationship between the built environment and childhood obesity,offering insights into potential interventions for *** such as urbanization,access to unhealthy food options,sedentary behaviors,and socioeconomic disparities are critical contributors to this complex *** environment encompasses the human-modified spaces such as homes,schools,workplaces,and urban *** settings can influence children’s physical activity levels,dietary habits,and overall *** built environment can be modified to prevent childhood obesity by enhancing active transportation through the development of safe walking and cycling routes,creating accessible and inviting green spaces and play areas,and promoting healthy food environments by regulating fast-food outlet *** design is another area for intervention,with a focus on integrating outdoor spaces and facilities that promote physical activity and healthy *** engagement and education in reinforcing healthy behaviors is necessary,alongside the potential of technology and innovation in encouraging physical activity among *** and legislative support are crucial for sustaining these *** conclusion,addressing the built environment in the fight against childhood obesity requires the need for a comprehensive,multipronged approach that leverages the built environment as a tool for promoting healthier lifestyles among children,ultimately paving the way for a healthier,more active future generation.

关键词： Non-communicable diseases Walkability Playgrounds Neighborhood green spaces Safety Pollution

“A stitch in time”: Intraoperative diaphragmatic injury during laparoscopic nephrectomy - A case of immediate recognition and expert management

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第1期7卷 44-47页

作者： Prakash Gyandev Gondode sridhar Panaiyadiyan Neha Garg Sakshi Duggal Department of Anaesthesiology Pain Medicine and Critical Care All India Institute of Medical SciencesNew DelhiIndia Department of Urology All India Institute of Medical SciencesNew DelhiIndia

Laparoscopy within the urology field has undergone a noteworthy surge in popularity over the past decade,with particular importance given to renal surgeries such as simple nephrectomy,radical nephrectomy,donor nephrectomy,nephroureterectomy,and partial nephrectomy.1 This shift toward laparoscopic procedures among urologists can be attributed to the many benefits of these procedures,including reduced postoperative pain,shorter hospital stays,and faster recovery times.2 However,as with any evolving surgical technique,laparoscopic procedures in renal surgery bring forth their own set of distinctive challenges and complications.

关键词： nephrectomy faster attributed

Emerging significance of butyrylcholinesterase

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World Journal of Experimental Medicine 2024年第1期14卷 33-43页

Butyrylcholinesterase(BChE;EC 3.***.1.8),an enzyme structurally related to acetylcholinesterase,is widely distributed in the human *** plays a role in the detoxification of chemicals such as succinylcholine,a muscle relaxant used in anesthetic *** is well-known due to variant forms of the enzyme with little or no hydrolytic activity which exist in some endogamous communities and result in prolonged apnea following the administration of *** other functions include the ability to hydrolyze acetylcholine,the cholinergic neurotransmitter in the brain,when its primary hydrolytic enzyme,acetylcholinesterase,is *** assess its potential roles,BChE was studied in relation to insulin resistance,type 2 diabetes mellitus,cognition,hepatic disorders,cardiovascular and cerebrovascular diseases,and inflammatory *** who lack the enzyme activity of BChE are otherwise healthy,until they are given drugs hydrolyzed by this ***,BChE is a candidate for the study of loss-of-function mutations in *** individuals with variant forms of BChE can provide insights into whether they are protected against metabolic *** potential utility of the enzyme as a biomarker for Alzheimer’s disease and the response to its drug treatment can also be assessed.

关键词： Esterase Acetylcholinesterase Variant Cholinergic Metabolic syndrome Cognition Knockout model

Is it necessary to stop glucagon-like peptide-1 receptor agonists prior to endoscopic procedure? A retrospective study

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World Journal of Gastroenterology 2024年第26期30卷 3221-3228页

作者： Haider Ghazanfar Nismat Javed Abeer Qasim Franklin Sosa Faryal Altaf Shazia Khan Jaydeep Mahasamudram Abhilasha Jyala Sameer Datta Kandhi Dongmin Shin Nikhitha Mantri Haozhe Sun Siddarth Hanumanthu Harish Patel Jasbir Makker Bhavna Balar Anil Dev sridhar Chilimuri Division of Gastroenterology Department of Internal MedicineBronxCare Health SystemIcahn School of Medicine at Mount SinaiBronxNY 10457United States Department of Internal Medicine BronxCare Health SystemIcahn School of Medicine at Mount SinaiBronxNY 10457United States

BACKGROUND Glucagon-like peptide-1 receptor agonists(GLP-1 RA)are effective in diabetes and obesity,reducing hyperglycemia by increasing insulin release and delaying gastric ***,they can cause gastroparesis,raising concerns about aspiration during *** guidelines advise discontinuing GLP-1 RA before surgery to reduce the risk of pulmonary *** To evaluate the effect of GLP-1 RAs on gastric residual contents during endosco-pic *** A retrospective chart review at BronxCare Health System,New York,from January 2019 to October 2023,assessed gastric residue and aspiration in GLP-1 RA patients undergoing endoscopic *** groups were compared based on dietary status before the *** included demographics,symptoms of gastroparesis,opiate use,hemoglobin A1c,GLP-1 agonist indication,endo-scopic details,and aspiration *** SPSS was used for analysis,cal-culating means,standard deviations,and applying Pearson’s chi-square and t-tests for associations,with P<0.05 as being *** During the study,306 patients were included,with 41.2%on a clear liquid/low residue diet and 58.8%on a regular diet before *** patients(63.1%)were male,with a mean age of 60±12 *** majority(85.6%)were on GLP-1 RAs for diabetes,and 10.1%reported digestive symptoms before *** those on a clear liquid diet,1.5%had residual food at endoscopy compared to 10%on a regular diet,which was statistically significant(P=0.03).Out of 31 patients with digestive symptoms,13%had residual food,all from the regular diet group(P=0.130).No complications were reported during or after the *** The study reflects a significant rise in GLP-1 RA use for diabetes and obesity.A 24-hour liquid diet seems safe for endoscopic procedures without *** with upper gastrointestinal symptoms might have a higher residual food risk,though not statistically *** research is needed

关键词： Glucagon-like peptide-1 agonists Gastroparesis Endoscopic procedures Residual food Complications