检索结果-南通市图书馆

Journal of Pharmaceutical Analysis 2014年第2期4卷 81-95页

作者： Hala H.Eldaroti suad a.gadir Moamen S.Refat Abdel Majid A.Adam Department of Chemistry Faculty of EducationAlzaeim Alazhari University Department of Chemistry Faculty of ScienceTaif University Department of Chemistry Faculty of SciencePort Said University

Investigation of charge-transfer （CT） complexes of drugs has been recognized as an important phenomenon in understanding of the drug-receptor binding mechanism. Structural, thermal, morpholo-gical and biological behavior of CT complexes formed between drug quinidine （Qui） as a donor and quinol （QL）, picric acid （PA） or dichlorodicyanobenzoquinone （DDQ） as acceptors were reported. The newly synthesized CT complexes have been spectroscopically characterized via elemental analysis;infrared （IR）, Raman, 1H NMR and electronic absorption spectroscopy; powder X-ray diffraction （PXRD）;thermogravimetric （TG） analysis and scanning electron microscopy （SEM）. It was found that the obtained complexes are nanoscale, semi-crystalline particles, thermally stable and spontaneous. The molecular composition of the obtained complexes was determined using spectrophotometric titration method and was found to be 1：1 ratios （donor：acceptor）. Finally, the biological activities of the obtained CT complexes were tested for their antibacterial activities. The results obtained herein are satisfactory for estimation of drug Qui in the pharmaceutical form

关键词： Quinidine Charge-transfer interac-tion Powder X-ray diffractionMorphology Thermal analysis

Functional response of Chrysoperla carnea （Neuroptera： Chrysopidae） to Helicoverpa armigera （Lepidoptera： Noctuidae） Effect of prey and predator stages

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insect Science 2011年第2期18卷 217-224页

作者： Mehdi Hassanpour Jafar Mohaghegh Shahzad Iranipour gadir Nouri-Ganbalani Annie Enkegaard Department of Plant Protection Faculty of Agriculture University of Mohaghegh Ardabili Ardabil Iranian Research Institute of Plant Protection (IRIPP) Tehran Department of Plant Protection Faculty of Agriculture University of Tabriz Tabriz Iran Department of Integrated Pest Management Research Centre Flakkebjerg Faculty of Agricultural Sciences Aarhus University Slagelse Denmark

Understanding predator-prey interactions has a pivotal role in biological control programs. This study evaluated the functional response of three larval instars of the green lacewing, Chrysoperla carnea （Stephens）, preying upon eggs and first instar larvae of the cotton bollworm, Helicoverpa armigera Hubner. The first and second instar larvae of C. carnea exhibited typeⅡ functional responses against both prey stages. However, the third instar larvae of C. carnea showed a type II functional response to the first instar larvae of H. armigera, but a typeⅢ functional response to the eggs. For the first instar larvae of C. carnea, the attack rate on H. armigera eggs was significantly higher than that on the larvae, whereas the attack rate of the second instar C. carnea on H. armigera larvae was significantly higher than that on the eggs. For the third instar larvae of C. carnea, the attack rate on the larvae was 1.015±0.278/h, and the attack coefficient on the eggs was 0.036 ±0.005. The handling times of the third instar larvae on larvae and eggs were 0.087 ± 0.009 and 0.071 ± 0.001 h, respectively. The highest predation rate was found for the third instar larvae of C. carnea on H. armigera eggs. Results of this study revealed that the larvae of C. carnea, especially the third instar, had a good predation potential in controlling H. armigera eggs and larvae. However, for a comprehensive estimation of the bio- control abilities of C. carnea toward H, armigera, further field-based studies are needed.

关键词： biological control Chrysoperla carnea Helicoverpa armigera predatorprey interactions

TGF-β信号缺陷是否是人类癌症中的致命弱点?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

癌症 2008年第8期27卷 882-884页

作者： David A.Foster Noga.gadir Department of Biological Sciences Hunter College of the City University of New YorkNew YorkUSA Department of Biological Sciences Hunter College of the City University of New YorkNew YorkNew YorkUSA Department of Molecular GeneticsWeizmann Institute of ScienceRehovot 76100Israel

癌细胞中的存活信号可激活mTOR-哺乳动物雷帕霉素靶蛋白。mTOR可抑制TGF-β信号,后者可使细胞周期停滞于G1后期,因此,活化后的mTOR可防止细胞周期停滞于TGF-β介导的检验点。雷帕霉素可重新激活TGF-β信号,从而导致G1期细胞停滞。在人... 详细信息

癌细胞中的存活信号可激活mTOR-哺乳动物雷帕霉素靶蛋白。mTOR可抑制TGF-β信号,后者可使细胞周期停滞于G1后期,因此,活化后的mTOR可防止细胞周期停滞于TGF-β介导的检验点。雷帕霉素可重新激活TGF-β信号,从而导致G1期细胞停滞。在人类癌症中,TGF-β信号通常发生缺陷,相反,在雷帕霉素作用下,TGF-β信号缺陷的癌细胞不发生G1期停滞,而发生凋亡。因此,在基于雷帕霉素的抗癌治疗策略中,TGF-β信号缺陷可能是癌细胞的致命弱点。

关键词： TGF-β mTOR 雷帕霉素凋亡存活信号癌细胞

Effect of water stress at different periods on seed yield and water use efficiency of guar under Shambat conditions

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Agricultural Sciences 2011年第3期2卷 262-266页

作者： Mahmoud Fadl el Mula Ahmed Deng Manasseh Mac Awatif Abdel gadir Bashir Faculty of Agriculture University of Khartoum Shambat 13314 Sudan Faculty of Agriculture University of Khartoum Shambat Sudan

Water stress effects on seed yield and water use efficiency of three indeterminate guar (Cyamopsis tetragonoloba L. Taub.) lines (L12, L18 and L33) were investigated in the experimental farm of the Faculty of Agriculture, University of Khartoum for two seasons (2005 and 2006). The guar lines were subjected to water stress induced by withholding irrigation for three weeks. Three water stress treatments were imposed 35, 50 and 65 days after sowing (DAS), and a control treatment irrigated every two weeks. The treatments were arranged in a split-plot design with three replications;with water regime treatments assigned to the main plots and guar lines to the subplots. Data were recorded on seed yield (***–1), number of pods per plant, 1000- seed weight (g), harvest index (HI) and water use efficiency at harvest. The results indicated that exposure of several cultivars of guar to water stress at the three stages of growth didn’t induce any significant effect on number of pods per plant, 1000-seed weight, seed yield and water use efficiency (WUE). On the other hand there was significant reduction in harvest index as a result of imposition of water stress at 35 and 50 DAS. It was also evident that plants re-watered after the stress recovered and had the same values as the control treatment.

关键词： Guar Water Stress Water Use Efficiency Harvest Index

Gross and Microscopic Lesions of the Ovaries of Camels from Abattoirs in Eastern Province of Kingdom of Saudi Arabia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Pathology 2022年第1期12卷 1-11页

作者： Adel I. Al-Afaleq Abdel gadir Musa Homeida Seif Eldawla Mustafa Barakat Mohamed Salim Moqbel College of Public Health Imam Abdulrahman Bin Faisal University Dammam KSA Department of Biology College of Science Imam Abdulrahman Bin Faisal University Dammam KSA Department of Anatomy College of Veterinary Medicine King Faisal University Al-Ahsa KSA Department of Pathology College of Veterinary Medicine King Faisal University Al-Ahsa KSA

In the present investigation, gross and microscopic lesions of the ovaries were studied in two hundred and ten (210) adult non-pregnant she-camels. Fresh samples of ovaries were collected from she-camels at the point of slaughter in Al-Ahsa abattoir, Eastern region of Kingdom of Saudi Arabia. These samples were subjected to histopathological studies and stained by routine Hematoxylin and Eosin stain. Grossly, of the 210 ovarian tissues examined, 30 (14.28%) had ovarian lesions of one type or another, whereas 180 (85.71%) camels were apparently healthy. Only 6 (2.85%) ovaries showed unilateral ovarian hypoplasia, whereas 4 (1.9%) showed bilateral ovarian hypoplasia. Cystic ovaries were observed in a total of 13 of the collected samples of ovaries, of these 8 (3.8%) were diagnosed as follicular cystic ovaries, while 5 (2.38%) were luteal cystic ovaries. Ovarian abscess appeared in only one sample of the collected ovaries. While ovarian tumors were observed in a total of 6 of the collected samples distributed as, two fibromas, three dermoid cysts, and only one hemangioma. The present study indicates that follicular cysts, luteal cysts and ovarian hypoplasia were the most common ovarian disorders in non-pregnant she-camels in Al-Ahsa region of the Eastern Province of Kingdom of Saudi Arabia.

关键词： Dromedary Camel Ovarian Lesions Saudi Arabia

A scoping review of studies on women's knowledge regarding Tdap vaccination during Pregnancy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Diseases Research 2023年第4期4卷 35-41页

作者： Rehab Saud Alghamdi Nahla Abdul-gadir Hassan Tayyib College of Nursing Umm Al-Qura UniversityMakkah 24382Kingdom of Saudi Arabia

This review aimed to determine and identify the knowledge and attitude of the mothers or pregnant women toward the Tdap vaccine during *** cough,Diphtheria disease and tetanus are infectious and pathogenic bacterial diseases that mainly affect children too young to complete basic vaccinations,and deaths associated with infectious diseases are frequent among ***,it is advisable for pregnant women to take the triple bacterial vaccine(tetanus,diphtheria and pertussis).This scoping review was conducted,and various electronic databases were searched,including Medline and ***,Google Scholar,CDC,and immunization research group websites were searched to investigate the literature on the Tdap *** a result,13 studies were included in this *** on the findings of this review,the level of knowledge of ladies and pregnant women about the importance of the vaccine depended upon several factors,including education level,occupation,age,sources of vaccine information,maternal desire,being born outside the country,lower household income,religious misconception,residing in a province or area where the pertussis vaccine was not free,having given birth to live children in the past,and receiving maternity care from a ***,it can be concluded that the increase in the level of knowledge about the importance of Tdap vaccine increased the percentage of women who supported and accepted the *** have also shown that some mothers refused vaccination due to reservations about vaccine safety and efficacy since they did not have sufficient knowledge or experience.

关键词： pregnant women vaccination pertussis Tdap vaccine knowledge

Effect of water stress at different periods on seed yield and water use efficiency of guar under Shambat conditions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

心脏转甲状腺素蛋白淀粉样变和轻链淀粉样变病人心肌细胞特异反应的心脏MRI研究

Agricultural Sciences（农业科学） 2011年第3期

作者： Mahmoud Fadl el Mula Ahmed Deng Manasseh Mac Awatif Abdel gadir Bashir

来源：评论

学校读者我要写书评

暂无评论

国际医学放射学杂志 2016年第1期 66-66页

作者： M.Fontana S.M.Banypersad T.A.Treibel A.a.gadir V.Maestrini T.Lane 杨献峰 Imaging Centre The Heart Hospital

摘要目的应用心脏MRI测量免疫球蛋白轻链淀粉样变(AL)和转甲状腺素蛋白淀粉样变(ATTR)的细胞外体积(ECV)和总细胞体积,以评估淀粉样物质和肌细胞的体积。材料与方法本研究经伦理委员会批准,所有参与者均签署书面知情同意书。257例受试者... 详细信息

摘要目的应用心脏MRI测量免疫球蛋白轻链淀粉样变(AL)和转甲状腺素蛋白淀粉样变(ATTR)的细胞外体积(ECV)和总细胞体积,以评估淀粉样物质和肌细胞的体积。材料与方法本研究经伦理委员会批准,所有参与者均签署书面知情同意书。257例受试者中,92例为AL,平均年龄(62±10)岁;44例为突变型ATTR,平均年龄(68±10)岁;66例为野生型ATTR,平均年龄(75±7)岁。此外,本研究中纳入了8例有ATTR突变的健康受试者,平均年龄(47±6)岁和47例健康志愿者,平均年龄(45±15)岁。全部受试者接受平衡对

关键词：淀粉样变蜡样变性病人 MRI 左心室心脏细胞外转甲状腺素蛋白