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Comparison of the Nerve Regeneration Capacity and Characteristics between Sciatic Nerve Crush and Transection Injury Models in Rats

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Biomedical and Environmental Sciences 2023年第2期36卷 160-173页

作者： WANG Bin Bin GUO Chao sun sheng qiao ZHANG Xing Nan LI Zhen LI Wei Jie LI De Zhi SCHUMACHER Michael LIU Song Beijing Neurosurgical Institute Capital Medical UniversityBeijing 100070China Department of Neurosurgery Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China U1195 Inserm et Universite Paris-SaclayLe Kremlin-Bicetre 94276France

Objective To provide useful information for selecting the most appropriate peripheral nerve injury model for different research purposes in nerve injury and repair studies,and to compare nerve regeneration capacity and characteristics between *** Sixty adult SD rats were randomly divided into two groups and underwent crush injury alone(group A,n=30)or transection injury followed by surgical repair(group B,n=30)of the right hind *** group was subjected to the CatWalk test,gastrocnemius muscle evaluation,pain threshold measurement,electrophysiological examination,retrograde neuronal labeling,and quantification of nerve regeneration before and 7,14,21,and 28 days after *** Gait analysis showed that the recovery speed in group A was significantly faster than that in group B at 14 *** 21 days,the compound muscle action potential of the gastrocnemius muscle in group A was significantly higher than that in group B,and the number of labeled motor neurons in group B was lower than that in group *** number of new myelin sheaths and the g-ratio were higher in group A than in group *** was a 7-day time difference in the regeneration rate between the two injury *** The regeneration of nerve fibers was rapid after crush nerve injury,whereas the transection injury was relatively slow,which provides some ideas for the selection of clinical research models.

关键词： Sciatic nerve injury Degeneration Regeneration Myelination

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农业观光旅游:游客满意度研究——以苏州未来农林大世界为例

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商业研究 2008年第9期 151-155页

作者：孙乔圣南京农业大学经济管理学院江苏南京210095

农业观光旅游是以保护自然生态环境为基础、开发农业旅游资源为重点的新型农业产业。以苏州未来农林大世界五一黄金周的游客为研究对象,针对游客的满意度进行细分,从各个层面考察游客的满意度,以及影响游客满意度的因素进行分析。结果显... 详细信息

农业观光旅游是以保护自然生态环境为基础、开发农业旅游资源为重点的新型农业产业。以苏州未来农林大世界五一黄金周的游客为研究对象,针对游客的满意度进行细分,从各个层面考察游客的满意度,以及影响游客满意度的因素进行分析。结果显示:农业观光旅游的认知水平普遍偏低,增加人们对农业观光旅游的认知程度十分重要,农业观光旅游经营者需要不断完善园内设施,提高服务质量。

关键词：农业观光旅游满意度苏州

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Plasmonic tandem heterojunctions enable high-efficiency charge transfer for broad spectrum photocatalytic hydrogen production

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Journal of Energy Chemistry 2025年第1期100卷 710-720页

作者： Wenxuan Chen Xiu-Qing qiao Guo Hui Bojing sun Dongfang Hou Meidi Wang Xueqian Wu Tao Wu Dong-sheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Hubei Three Gorges Laboratory College of Chemistry and Materials Science and Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University

Rational engineering of semiconductor photocatalysts for efficient hydrogen production is of great significance but still challenging,primarily due to the limitations in charge transfer ***,a fascinating plasmonic tandem heterojunction with the hc-CdS/Mo2C@C heterostructure is aimfully prepared for effectively promoting the charge separation kinetics of the CdS photocatalyst via the synergistic strategy of phase junction,Schottky junction,and photothermal *** difference in atomic configuration between cubic-CdS （c-CdS） and hexagonal-CdS （h-CdS） leads to effective charge separation through a typical Ⅱ charge transfer mechanism,and plasmonic Schottky junction further extracts the electrons in the hc-CdS phase junction to realize gradient charge ***,the photothermal effect of Mo2C@C helps to expand the light absorption,accelerate charge transfer kinetics,and reduce the hydrogen evolution energy *** carbon layer provides a fast channel for charge transfer and protects the photocatalyst from *** a result,the optimized hc-CMC photocatalyst exhibits a significantly high photocatalytic H2production activity of 28.63 mmol/g/h and apparent quantum efficiency of 61.8%,surpassing most of the reported *** study provides a feasible strategy to enhance the charge transfer kinetics and photocatalytic activity of CdS by constructing plasmonic tandem heterogeneous junctions.

关键词： Heterojunctions LSPR Photocatalyst Phase junction Schottky junction Photothermal effect

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Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-Min Xing Hai-Dong Qian qiao Gao sheng-Lan Xu Hua Ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

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小茴香挥发油提取工艺优化及抗氧化研究

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中国调味品 2020年第2期45卷 68-71页

作者：马延红孙侨生段志芳刘文华肇庆学院生命科学学院

以小茴香为试验对象,以水蒸气蒸馏法提取小茴香精油。采用正交试验法对工艺进行优化,以挥发油提取率为指标,对料液比、粉碎粒度、浸泡时间和蒸馏时间4个因素进行考察,并初步评价小茴香挥发油的体外抗氧化活性。结果表明:最佳提取工艺参... 详细信息

以小茴香为试验对象,以水蒸气蒸馏法提取小茴香精油。采用正交试验法对工艺进行优化,以挥发油提取率为指标,对料液比、粉碎粒度、浸泡时间和蒸馏时间4个因素进行考察,并初步评价小茴香挥发油的体外抗氧化活性。结果表明:最佳提取工艺参数为料液比1∶25,粉碎粒度100目,浸泡时间1h,蒸馏时间6h,在此蒸馏条件下小茴香的出油率为3.64%。体外抗氧化活性试验结果表明:小茴香挥发油的总还原能力、羟自由基清除率和DDPH·清除率与浓度呈正相关,抗氧化活性效果良好。

关键词：小茴香挥发油水蒸气蒸馏法工艺优化抗氧化活性香料精油

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Processing map and dynamic recrystallization behaviours of 316LN-Mn austenitic stainless steel

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International Journal of Minerals,Metallurgy and Materials 2023年第12期30卷 2386-2396页

作者： Shaolong sheng Yanxin qiao Ruzong Zhai Mingyue sun Bin Xu School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China Institute of Metal Research Chinese Academy of SciencesShenyang 110016China Key Laboratory of Electromagnetic Processing of Materials(Ministry of Education) Northeastern UniversityShenyang 110819China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China

The hot deformation behaviours of 316LN-Mn austenitic stainless steel were investigated by uniaxial isothermal compression tests at different temperatures and strain *** microstructural evolutions were also studied using electron backscatter *** flow stress decreases with the increasing temperature and decreasing strain rate.A constitutive equation was established to characterize the relationship among the deformation parameters,and the deformation activation energy was calculated to be 497.92 k J/*** maps were constructed to describe the appropriate processing window,and the optimum processing parameters were determined at a temperature of 1107-1160℃ and a strain rate of 0.005-0.026 s^(-1).Experimental results showed that the main nucleation mechanism is discontinuous dynamic recrystallization(DDRX),followed by continuous dynamic recrystallization(CDRX).In addition,the formation of twin boundaries facilitated the nucleation of dynamic recrystallization.

关键词： austenitic stainless steel processing map dynamic recrystallization constitutive equation

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N-Widths and Average Widths of Besov Classes in Sobolev Spaces

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Acta Mathematica Sinica,English Series 2006年第6期22卷 1667-1678页

作者： Gui qiao XU Yong sheng sun Yong Ping LIU School of Mathematical Sciences Beijing Normal University Beijing 100875 P. R. China School of Mathematical Sciences Tianjin Normal University Tianjin 300074 P. R. China

In this paper, we consider the n-widths and average widths of Besov classes in the usual Sobolev spaces. The weak asymptotic results concerning the Kolmogorov n-widths, the linear n-widths, the Gel＇fand n-widths, in the Sobolev spaces on T^d, and the infinite-dimensional widths and the average widths in the Sobolev spaces on Ra are obtained, respectively.

关键词： Besov class n-width Sobolev space Average width

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Statics, vibration, and buckling of sandwich plates with metamaterial cores characterized by negative thermal expansion and negative Poisson's ratio

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Applied Mathematics and Mechanics(English Edition) 2023年第9期44卷 1457-1486页

作者： qiao ZHANG Yuxin sun National Key Laboratory of Strength and Structural Integrity School of Aeronautic Science and EngineeringBeihang UniversityBeijing 100191China

This paper proposes a three-dimensional(3D)Maltese cross metamaterial with negative Poisson’s ratio(NPR)and negative thermal expansion(NTE)adopted as the core layers in sandwich plates,and aims to explore the relations between the mechanical responses of sandwich composites and the NPR or NTE of the ***,the NPR and NTE of the metamaterial are derived analytically based on energy *** effective elastic modulus and mass density of the 3D metamaterial are obtained and validated by the finite element method(FEM).Subsequently,the general governing equation of the 3D sandwich plate under thermal environments is established based on Hamilton’s principle with the consideration of the von Kármán *** differential quadrature(DQ)FEM(DQFEM)is utilized to obtain the numerical *** is shown that NPR and NTE can enhance the global stiffness of sandwich *** geometric parameters of the Maltese cross metamaterial significantly affect the responses of the thermal stress,natural frequency,and critical buckling load.

关键词： negative Poisson's ratio(NPR) negative thermal expansion(NTE) sand-wich plate vibration buckling

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Effects of altitude and slope on the climate–radial growth relationships of Larix olgensis *** in the southern Lesser Khingan Mountains,Northeast China

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Ecological Processes 2022年第1期11卷 618-630页

作者： Jingjing qiao Yujun sun National Forestry&Grassland Administration Key Laboratory of Forest Resources&Environmental Management Beijing Forestry UniversityBeijing 100083China

Background:The relationship between climate and radial growth of trees exhibits spatial variation due to environ-mental ***,elucidation of how the growth–climate responses of trees vary in space is essential for understanding forest growth dynamics to facilitate scientific management with the ongoing global climate *** explore the altitudinal and slope variations of these interactions,tree-ring width chronologies of Larix olgensis *** were analyzed in the southern Lesser Khingan Mountains,Northeast ***:The radial growth of *** exhibited significant 5-to 10-year periodic changes at three altitudes and two slopes,and the frequency change occurred mainly during the early growth stage and after *** radial growth of *** was significantly negatively correlated with September precipitation only at low altitudes,but also with the mean temperature in July–August and the mean maximum temperature in June–August at high *** radial growth of *** at low and middle altitudes as well as on the sunny slope led to a higher demand for moisture,while temperature was the key limiting factor at high altitudes and on the shady ***:The climate–radial growth relationship of *** exhibits altitudinal and slope *** study quantitatively describes the spatially varying growth–climate responses of *** in the southern Lesser Khingan Mountains,which provides basic data for the management of *** forests and the prediction of future climate impacts on forest ecosystems.

关键词： Larix olgensis A.Henry Altitudinal gradient Slope variability Lesser Khingan Mountains

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Augmented reality-based BIM multi-user collaboration system

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The Journal of China Universities of Posts and Telecommunications 2022年第1期29卷 71-80页

作者： sun Heng qiao Xiuquan Shanxi Transportation Planning Survey and Design Institute Company Limited Taiyuan 030024China State Key Laboratory of Networking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing 100876China

The rapid development of building information modelling(BIM) and its enabling technologies has attracted extensive attention in the field of architecture, engineering and construction(AEC). By combining BIM models with the real world, the potential of BIM can be further exploited with the help of augmented reality(AR) technology. However, a BIM model usually involves a huge amount of data. Considering the limited computing capability of current mobile devices, these applications therefore suffer from significant performance problems, especially model loading and rendering problems. To this end, an AR-based multi-user BIM collaboration system, which can realise the on-demand dynamical loading of the BIM model by using the block-wise loading strategy of model transformation, thus solving the problem of model loading delay, was proposed. In addition, dynamic rendering technology is adopted to solve the problem of rendering lag. Experimental results show that the realisation of virtual-reality fusion and interaction for the BIM model and remote multi-user collaboration can effectively improve work efficiency and intelligence in the engineering field.

关键词： building information modelling augmented reality multi-user collaboration block-wise loading dynamic rendering

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