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Corrosion behaviour of NiCrFeAl-hBN seal coatings in oxidation environments at a high temperature

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Rare Metals 2021年第1期40卷 212-218页

作者： su-yuan yang Dan Guo Xing-Wang Cheng Jian-Ming Liu Yue-Guang Yu School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081.China National Key Laboratory of Science and Technol Beijing General Research

The purpose of this investigation was to evaluate the microstructure,high-temperature oxidation behaviour,and hardness of a seal coating under controlled exposures at 750℃with different exposure *** results reveal that the main phases in the coating are Ni,FeNi3,and hexagonal BN,withα-Al_(2)O_(3)peaks appearing after 2-h *** the exposure time increases,the diffraction peak intensity ofα-Al_(2)O_(3)begins to decrease and Cr_(2)O_(3)peaks appear after 200 *** 1000 h,Cr_(2)O_(3)becomes dominant with only small amounts ofα-Al_(2)O_(3)*** high-temperature oxidation process of the coating includes three stages:the fast stage,transition stage,and slow *** oxidation rate is constant in each stage,and in the fast stage and slow stages with values of7.9×10^(-4)and 8.37×10^(-5)mg^(2)·cm^(-4)·s^(-1),***,α-Al_(2)O_(3)forms near the pores in the coating,followed by the formation of Cr_(2)O_(3).As the exposure time increases,oxidation penetrates into the interior of the coating along phase boundaries to form island-shaped inner oxide layers with high concentrations of Cr,Ni,and ***,hardness increases with increasing oxide percentage.

关键词： NiCrFeAl-hBN Seal coating Oxidation Microstructure High temperature

A Matched Comparison Study of Uniportal Versus Triportal Thoracoscopic Lobectomy and sublobectomy for Early-stage Nonsmall Cell Lung Cancer

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Chinese Medical Journal 2015年第20期128卷 2731-2735页

作者： Ju-Wei Mu Shu-Geng Gao Qi Xue Jun Zhao Ning Li Kun yang Kai su Zhu-yang yuan Jie He Department of Thoracic surgery Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China

Background： Both uniportal and triportal thoracoscopic lobectomy and sublobectomy are feasible for early-stage non-small cell lung cancer （NSCLC）. The aim of this study was to compare the perioperative outcomes of uniportal and triportal thoracoscopic Iobectomy and sublobectomy for early-stage NSCLC. Methods： A total of 405 patients with lung lesions underwent thoracoscopic lobectomy or sublobectomy through a uniportal or triportal procedure in approximately 7-month period （From November 2014 to May 2015）. A propensity-matched analysis, incorporating preoperative variables, was used to compare the short-term outcomes of patients who received uniportal or triportal thoracoscopic lobectomy and sublobectomy. Results： Fifty-eight patients underwent uniportal and 347 patients underwent triportal pulmonary resection. The conversion rate for uniportal and triportal procedure was 3.4% （2/58） and 2.3% （8/347）, respectively. The complication rate for uniportal and triportal procedure was 10.3% and 9.5%, respectively. There was no perioperative death in either group. Most patients had early-stage NSCLC in both groups （uniportal： 45/47, 96%; triportal： 313/343, 91%）. Propensity score-matching analysis demonstrated no significant differences in operation time, intraoperative blood loss, numbers of dissected lymph nodes, number of stations of lymph node dissected, duration of chest tube, and complication rate between uniportal and triportal group for early-stage NSCLC. However, the duration of postoperative hospitalization was longer in the uniportal group （6.83 ± 4.17 vs. 5.42 ± 1.86 d, P = 0.036） compared with the triportal group. Conclusions： Uniportal thoracoscopic lobectomy and sublobectomy is safe and feasible, with comparable short-term outcomes with triportal thoracoscopic pulmonary resection. Uniportal lobectomy and sublobectomy lead to similar cure rate as triportal Iobectomy and sublobectomy for early NSCLC.

关键词： Early-stage Nonsmall Cell Lung Cancer Lobectomy sublobectomy Uniportal Video-assisted Thoracoscopic surgery

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池塘蓄水养蛏提高产量的关键技术

水产科技情报 2006年第6期33卷 275-277页

作者：苏仰源福建省宁德市蕉城区水产技术推广站宁德市352100

池塘蓄水养殖缢蛏是一种高产、高效、优质的养殖模式,具有生长快、养殖周期短、产量高、单位成本低等优点。池塘蓄水养蛏,提高产量的关键是严格掌握并有效地控制水质、饵料、底质三要素。

关键词：缢蛏池塘养殖水质饵料底质

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自然海区缢蛏苗种生产技术

水产科技情报 2006年第2期33卷 53-55页

作者：苏仰源福建省宁德市蕉城区水产技术推广站宁德市352100

用平畦预报技术指导自然海区缢蛏苗种生产,重点介绍苗埕选择、苗埕建造、平畦预报、以及蛏苗附苗后的管理。

关键词：缢蛏平畦预报海区采苗

Sex differences in aging and injured brain

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Neural Regeneration Research 2025年第10期20卷 2901-2902页

作者： Jordan N.Williamson yuan yang University of Illinois Urbana-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foundation Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA University of Illinois Urbana-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA Northwestern University Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Huntington’s disease)differ substantially between males and *** higher prevalence of these brain disorders has been attributed to females having a greater longevity compared with *** one of the greatest risk factors of acquired brain injury(such as stroke,traumatic brain injury caused by fall)and neurodegenerative disease is age.

关键词： Huntington prevalence traumatic

健康体检成年人群幽门螺杆菌感染的相关因素研究

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中国现代医学杂志 2016年第12期26卷 127-130页

作者：包英杨元素罗丹凉山州中西医结合医院内一科四川凉州615000

目的探究凉山州中西医结合医院健康体检成年人群幽门螺杆菌(HP)感染的相关因素,为成年人群的健康体检和预防幽门螺杆菌感染提供参考依据。方法选取2013年1月-2015年1月来本院进行健康检查的800例成年人群为研究对象。采用13C呼气试验对... 详细信息

目的探究凉山州中西医结合医院健康体检成年人群幽门螺杆菌(HP)感染的相关因素,为成年人群的健康体检和预防幽门螺杆菌感染提供参考依据。方法选取2013年1月-2015年1月来本院进行健康检查的800例成年人群为研究对象。采用13C呼气试验对幽门螺杆菌感染率进行检测,并分析健康体检成年人群HP感染的相关因素。结果单因素分析结果显示,性别、年龄、婚姻状况、家庭成员、胃病治疗史、饮酒史、吸烟史、生吃果蔬前削皮以及平时饮用什么水与健康体检成年人群HP感染有密切相关性(P<0.05)。多因素Logistic分析结果显示,男性、中年、多家庭成员、有胃病治疗史、有饮酒史、有吸烟史以及生吃果蔬前从不削皮为健康体检成年人群幽门螺杆菌感染的危险因素(P<0.05)。结论应当对男性、中年、多家庭成员、有胃病治疗史、有饮酒史、有吸烟史以及生吃果蔬前从不削皮的人群加强监测,预防幽门螺杆菌感染的发生,做到早发现早治疗。

关键词：健康体检成年人群幽门螺杆菌感染相关因素

止血与凝血指标在乙肝与肝硬化及肝脏衰竭患者中的改变规律研究

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中国现代医学杂志 2016年第8期26卷 56-59页

作者：包英杨元素罗丹四川省凉山州中西医结合医院内一科四川凉州615000

目的探讨不同止凝血指标在乙肝、肝硬化及肝衰竭患者中的变化规律。方法选取2014年1-12月于该院治疗的69例乙肝患者和同期30例健康体检者为研究对象。乙肝患者根据病情分为慢性乙肝组（23例）、肝硬化组（26例）及肝衰竭组（20例）。检... 详细信息

目的探讨不同止凝血指标在乙肝、肝硬化及肝衰竭患者中的变化规律。方法选取2014年1-12月于该院治疗的69例乙肝患者和同期30例健康体检者为研究对象。乙肝患者根据病情分为慢性乙肝组（23例）、肝硬化组（26例）及肝衰竭组（20例）。检测所有入组患者的凝血功能指标,主要包括凝血酶原时间（PT）、凝血酶原活动度（PTA）、活化部分凝血活酶时间（APTT）、凝血酶时间（TT）及纤维蛋白原（Fg）,检测不同组患者的抗凝指标（PC和AT-Ⅲ）、纤溶降解产物（FDP和D-D）及内皮细胞产生的组织因子途径抑制物（TFPI）、组织因子（TF）及血栓调节蛋白（TM）,比较不同凝血指标在各肝脏疾病中的变化。结果 PT、APTT及TT在肝硬化组及肝衰竭组显著延长,而PTA及Fg显著下降,差异有统计学意义（P〈0.05）。在肝硬化患者中,随着肝功能下降,患者PT、APTT及TT延长,PTA和Fg下降（P〈0.05）。与HBV-DNA阴性患者比较,HBV-DNA阳性患者的PT、APTT及TT显著延长,而PTA和Fg明显下降（P〈0.05）。常见的抗凝指标PC：A及AT-Ⅲ：A在不同肝病中差异有统计学意义（P〈0.05）,纤溶降解产物FDP及D-D随着病情的进展逐渐增高（P〈0.05）。内皮细胞合成的凝血功能相关指标TFPI：Ag及TF：Ag在慢性乙肝、肝硬化及肝衰竭患者中差异有统计学意义（P〈0.05）;与健康对照组比较,各肝病组患者TM：Ag水平显著升高,差异有统计学意义（P〈0.05）。结论随着肝脏疾病的进展,患者的凝血障碍逐渐加重,抗凝及纤溶活性增强,止凝血指标的检测对了解患者肝脏的损害程度、出凝血功能状况、出血倾向有着重要的意义。

关键词：慢性乙肝肝硬化肝功能衰竭凝血因子

Deep eutectic solvents for separation and purification applications in critical metal metallurgy:Recent advances and perspectives

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 1-19页

作者： Shuo Chen Shengpeng su Yanfang Huang Bingbing Liu Hu sun Shuzhen yang Guihong Han School of Chemical Engineering Zhengzhou UniversityZhengzhou 450001China Zhongyuan Critical Metals Laboratory Henan ProvinceZhengzhou 450001China

Solvent extraction,a separation and purification technology,is crucial in critical metal *** solvents commonly used in solvent extraction exhibit disadvantages,such as high volatility,high toxicity,and flammability,causing a spectrum of hazards to human health and environmental *** solvents have been recognized as potential alternatives to these harmful organic *** the past two decades,several neoteric solvents have been proposed,including ionic liquids(ILs)and deep eutectic solvents(DESs).DESs have gradually become the focus of green solvents owing to several advantages,namely,low toxicity,degradability,and low *** this critical review,their classification,formation mechanisms,preparation methods,characterization technologies,and special physicochemical properties based on the most recent advancements in research have been systematically ***,the major separation and purification applications of DESs in critical metal metallurgy were comprehensively ***,future opportunities and challenges of DESs were explored in the current research *** conclusion,this review provides valuable insights for improving our overall understanding of DESs,and it holds important potential for expanding separation and purification applications in critical metal metallurgy.

关键词： deep eutectic solvents preparations properties separation and purification critical metal metallurgy

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

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Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli Zhang Tian Li Jie Miao Zhina Zhang Mingxuan yang Zhuoran Wang Bo yang Jiawei Zhang Haiting Li Qiang su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1