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Vitamin A regulates mitochondrial biogenesis and function through p38 MAPK‑PGC‑1α signaling pathway and alters the muscle fiber composition of sheep

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Journal of Animal Science and Biotechnology 2024年第2期15卷 898-910页

作者： Pengkang Song Jiamin zhao Fanqinyu Li Xiaoyi zhao Jinxin Feng Yuan su Bo Wang Junxing zhao College of Animal Science Shanxi Agricultural UniversityTaiguShanxi 030801People’s Republic of China State Key Laboratory of Animal Nutrition and Feeding Department of Animal Nutrition and Feed ScienceCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193People’s Republic of China

Background Vitamin A(VA)and its metabolite,retinoic acid(RA),are of great interest for their wide range of physiological functions.However,the regulatory contribution of VA to mitochondrial and muscle fiber composition in sheep has not been reported.Method Lambs were injected with 0(control)or 7,500 IU VA palmitate into the biceps femoris muscle on d 2 after birth.At the age of 3 and 32 weeks,longissimus dorsi(LD)muscle samples were obtained to explore the effect of VA on myofiber type composition.In vitro,we investigated the effects of RA on myofiber type composition and intrinsic mechanisms.Results The proportion of type I myofiber was greatly increased in VA-treated sheep in LD muscle at harvest.VA greatly promoted mitochondrial biogenesis and function in LD muscle of sheep.Further exploration revealed that VA elevated PGC-1αmRNA and protein contents,and enhanced the level of p38 MAPK phosphorylation in LD muscle of sheep.In addition,the number of type I myofibers with RA treatment was significantly increased,and type IIx myofibers was significantly decreased in primary myoblasts.Consistent with in vivo experiment,RA significantly improved mitochondrial biogenesis and function in primary myoblasts of sheep.We then used si-PGC-1αto inhibit PGC-1αexpression and found that si-PGC-1αsignificantly abrogated RA-induced the formation of type I myofibers,mitochondrial biogenesis,MitoTracker staining intensity,UQCRC1 and ATP5A1 expression,SDH activity,and enhanced the level of type IIx muscle fibers.These data suggested that RA improved mitochondrial biogenesis and function by promoting PGC-1αexpression,and increased type I myofibers.In order to prove that the effect of RA on the level of PGC-1αis caused by p38 MAPK signaling,we inhibited the p38 MAPK signaling using a p38 MAPK inhibitor,which significantly reduced RA-induced PGC-1αand MyHC I levels.Conclusion VA promoted PGC-1αexpression through the p38 MAPK signaling pathway,improved mitochondrial biogenesis,and altered the composition of muscle fiber type.

关键词： Mitochondria Muscle fiber type PGC-1α p38 MAPK Retinoic acid Vitamin A

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Numerical simulation of microwave-induced cracking and melting of granite based on mineral microscopic models

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International Journal of Minerals,Metallurgy and Materials 2024年第7期31卷 1512-1524页

作者： Xiaoli su Diyuan Li Junjie zhao Mimi Wang Xing su Aohui Zhou School of Resources and Safety Engineering Central South UniversityChangsha 410083China

This study introduces a coupled electromagnetic–thermal–mechanical model to reveal the mechanisms of microcracking and mineral melting of polymineralic rocks under microwave radiation.Experimental tests validate the rationality of the proposed model.Embedding microscopic mineral sections into the granite model for simulation shows that uneven temperature gradients create distinct molten,porous,and nonmolten zones on the fracture surface.Moreover,the varying thermal expansion coefficients and Young's moduli among the minerals induce significant thermal stress at the mineral boundaries.Quartz and biotite with higher thermal expansion coefficients are subjected to compression,whereas plagioclase with smaller coefficients experiences tensile stress.In the molten zone,quartz undergoes transgranular cracking due to theα–βphase transition.The local high temperatures also induce melting phase transitions in biotite and feldspar.This numerical study provides new insights into the distribution of thermal stress and mineral phase changes in rocks under microwave irradiation.

关键词： microwave numerical modeling microcracking phase change granite

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Power equipment vibration visualization using intelligent sensing method based on event-sensing principle

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Global Energy Interconnection 2024年第2期7卷 228-240页

作者： Mingzhe zhao Xiaojun Shen Lei su Zihang Dong Tongji University No.1239 Siping RoadYangpu DistrictShanghai 200092P.R.China State Grid Shanghai Municipal Electric Power Company Electric Power Science Research Institute Shanghai 200437P.R.China Department of Electrical and Electronic Engineering Imperial College LondonLondonSW72AZU.K.

Vibration measurements can be used to evaluate the operation status of power equipment and are widely applied in equipment quality inspection and fault identification.Event-sensing technology can sense the change in surface light intensity caused by object vibration and provide a visual description of vibration behavior.Based on the analysis of the principle underlying the transformation of vibration behavior into event flow data by an event sensor,this paper proposes an algorithm to reconstruct event flow data into a relationship correlating vibration displacement and time to extract the amplitude-frequency characteristics of the vibration signal.A vibration measurement test platform is constructed,and feasibility and effectiveness tests are performed for the vibration motor and other power equipment.The results show that event-sensing technology can effectively perceive the surface vibration behavior of power and provide a wide dynamic range.Furthermore,the vibration measurement and visualization algorithm for power equipment constructed using this technology offers high measurement accuracy and efficiency.The results of this study provide a new noncontact and visual method for locating vibrations and performing amplitude-frequency analysis on power equipment.

关键词： Power equipment Event sensing Non contact measurement Graphic display Feasibility

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Research on a multi‑dimensional image information fusion algorithm based on NSCT transform

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Frontiers of Optoelectronics 2024年第1期17卷 29-44页

作者： Yuxiang su Xi Liang Danhua Cao Zhenyu Yang Yuanlong Peng Ming zhao School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China State Grid Information and Telecommunication Branch Beijing 100761China

Traditional inspection cameras determine targets and detect defects by capturing images of their light intensity,but in complex environments,the accuracy of inspection may decrease.Information based on polarization of light can characterize various features of a material,such as the roughness,texture,and refractive index,thus improving classification and recognition of targets.This paper uses a method based on noise template threshold matching to denoise and preprocess polarized images.It also reports on design of an image fusion algorithm,based on NSCT transform,to fuse light intensity images and polarized images.The results show that the fused image improves both subjective and objective evaluation indicators,relative to the source image,and can better preserve edge information and help to improve the accuracy of target recognition.This study provides a reference for the comprehensive application of multi-dimensional optical information in power inspection.

关键词： Power inspection Object detection Polarization imaging Image fusion Image denoising

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On the Infinite-Dimensional Modular Lie superalgebras of O-Type

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Algebra Colloquium 2024年第2期31卷 347-360页

作者： Xiaoning Xu Jing zhao Yucai su School of Mathematics and Statistics Liaoning UniversityShenyang 110036China 不详

The natural filtrations of infinite-dimensional Lie superalgebras of O-type over a field of positive characteristic are proved to be invariant under automorphisms by studying ad-nilpotent elements.We observe that two Lie superalgebras of O-type are isomorphic if and only if the integers in the definition of these Lie superalgebras are intrinsic.Thereby,all the Lie superalgebras of O-type are classified in the sense of isomorphism.

关键词： filtration isomorphism classification

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Tracking lithiation with transmission electron microscopy

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Science China Chemistry 2024年第1期67卷 291-311页

作者： Xincheng Lei Jianxiong zhao Jiayi Wang Dong su Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China South China Academy of Advanced Optoelectronics&International Academy of Optoelectronics at zhaoqing South China Normal UniversityGuangzhou 510006China

Li-ion batteries(LIBs)have dominated energy-storage techniques for portable electronic devices and electric cars,and are expanding their territory into the large-scale energy storage.The energy storage of LIBs is realized by the reversible shuttle of lithium ions between electrodes.It is essential to track the lithium diffusion and obtain a profound insight into the lithiation mechanism during the work cycle of LIBs.Transmission electron microscopy(TEM)is a powerful tool for the structural characterization,which can provide the information about the lithiation at the atomic scale.In this review,we summarize the research frontiers of TEM applications on LIBs.We introduce the techniques for the direct observation of Li species in LIB-related materials.Especially,the application of cryo-TEM is highlighted.Moreover,in-situ TEM technique is further discussed since it shows great advantages in studying the dynamical structure changes of LIBs.The perspectives and strategies in this review offer feasible guidance for researchers to further improve the performance of LIBs.

关键词： lithium-ion battery electrode materials transmission electron microscopy cryo-TEM in-situ TEM

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Reversible isomerization of donor-acceptor Stenhouse adduct derivatives in water through dendritic confinement

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Science China Chemistry 2024年第5期67卷 1636-1646页

作者： Jiaxing Zhang Qingyun zhao Xinyan su Afang Zhang Wen Li International Joint Laboratory of Biomimetic and Smart Polymers School of Materials Science and EngineeringShanghai UniversityShanghai 200444China

Modulating reversible isomerization of hydrophobic dyes in aqueous solutions is greatly desired. Here we report on reversible isomerization of solvatochromic donor-acceptor Stenhouse adducts(DASAs) in water through the confinement from dendritic oligoethylene glycols(OEGs). Dendronization of DASAs with dendritic OEGs affords them characteristic thermoresponsiveness. These dendronized DASAs spontaneously isomerize in water from hydrophobic linear state into hydrophilic cyclic state at room temperature due to the strong hydration. However, hydrophobic microenvironment through thermally dehydration and collapse of the dendritic OEGs at elevated temperatures confines hydration of the DASA moieties and mediates their interactions with the collapsed hydrophobic OEG domains, affording their isomerization recovery in water efficiently from the hydrophilic cyclic state into the hydrophobic linear state. The confinement-mediated reversible isomerization of DASA moieties in water can be repeated through alternative photo-irradiation and thermal dehydrations, exhibiting excellent fatigue resistance.

关键词： dendrimers donor-acceptor Stenhouse adducts isomerization confinement thermoresponsiveness

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Alternative technology for the recovery of butyl acetate with low concentration:high capacity adsorbent and high efficiency adsorption

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Green Chemical Engineering 2024年第2期5卷 236-244页

作者： Chi Ma Lihong zhao Zhengxin Mao Hao su Qingfen Liu CAS Key Laboratory of Green Process and Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China

Industrial pharmaceutical wastewater usually contains butyl acetate(BA)with a concentration of 1 wt%-7 wt%,and the traditional method for BA recovery is distillation with high energy consumption.Adsorption method is developed to recover BA with low concentration for the high efficiency and low energy consumption.Medium polar polyacrylate resins with macroporous structure of 233.1 nm and average particle size of about 526.5μm are successfully synthesized by suspension polymerization and used for the BA adsorption and desorption.The maximum adsorption capacity reaches 171.1 mg g^(-1)with relative standard deviation(RSD)value of 0.2%,which is more than twice the results in the literature.The BA desorption rate is 97.0%at 100℃with RSD value of 0.4%,and the resins are beneficial to the reuse in the adsorption-desorption cycle.The adsorption thermodynamics and kinetics are investigated,and the BA adsorption is a spontaneous and endothermic process with the increase of disorder degree.This process is mainly contributed by physical absorption and agree well with Freundlich model and pseudo-first-order adsorption kinetic model.The adsorption method avoids boiling a large amount of wastewater and hopefully provides a novel alternative technology for the BA recovery.

关键词： Butyl acetate recovery Resin adsorption Desorption Thermodynamics Kinetics

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A Comprehensive Overview of CFN From a Commonsense Perspective

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Machine Intelligence Research 2024年第2期21卷 239-256页

作者： Ru Li Yunxiao zhao Zhiqiang Wang Xuefeng su Shaoru Guo Yong Guan Xiaoqi Han Hongyan zhao Key Laboratory of Computational Intelligence and Chinese Information Processing of Ministry of Education School of Computer and Information TechnologyShanxi UniversityTaiyuan 030006China

Chinese FrameNet(CFN)is a scenario commonsense knowledge base(CKB)that plays an important role in research on Chinese language understanding.It is based on the theory of frame semantics and English FrameNet(FN).The CFN knowledge base contains a wealth of scenario commonsense knowledge,including frames,frame elements,and frame relations,as well as annotated instances with rich scenario-related labels on Chinese sentences and discourses.In this paper,we conduct a comprehensive overview of CFN from a commonsense perspective,covering topics such as scenario commonsense representation,CFN resources,and its applications.We also summarize recent breakthroughs and identify future research directions.First,we introduce the concept of scenario commonsense,including its definitions,examples,and representation methods,with a focus on the relationship between scenario commonsense and the frame concept in CFN.In addition,we provide a comprehensive overview of CFN resources and their applications,highlighting the newly proposed frame-based discourse representation and a human-machine collaboration framework for expanding the CFN corpus.Furthermore,we explore emerging topics such as expanding the CFN resource,improving the interpretability of machine reading comprehension,and using scenario CKBs for text generation.

关键词： Chinese FrameNet(CFN) commonsense scenario commonsense frame knowledge

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Exploring the impacts of major events on the systemic risk of the international energy market

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Petroleum Science 2024年第2期21卷 1444-1457页

作者： Ming-Tao zhao su-Wan Lu Lian-Biao Cui School of Statistics and Applied Mathematics Anhui University of Finance and EconomicsBengbu233030AnhuiChina Anhui Province Key Laboratory of Philosophy and Social Science of Low-Carbon Development and Carbon Finance Anhui University of Finance and EconomicsBengbu233030AnhuiChina

This study examines the systemic risk caused by major events in the international energy market(IEM)and proposes a management strategy to mitigate it. Using the tail-event driven network(TENET)method, this study constructed a tail-risk spillover network(TRSN) of IEM and simulated the dynamic spillover tail-risk process through the cascading failure mechanism. The study found that renewable energy markets contributed more to systemic risk during the Paris Agreement and the COVID-19pandemic, while fossil energy markets played a larger role during the Russia-Ukraine conflict. This study identifies systemically important markets(SM) and critical tail-risk spillover paths as potential sources of systemic risk. The research confirms that cutting off the IEM risk spillover path can greatly reduce systemic risk and the influence of SM. This study offers insights into the management of systemic risk in IEM and provides policy recommendations to reduce the impact of shock events.

关键词： International energy market Tail-risk spillover Cascading failure mechanism Systemic risk management

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