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世界核心医学期刊文摘（心脏病学分册） 2007年第10期3卷 52-53页

作者： Giugliano R.p. Wiviott S.D. stone p.h. 孙凯 TIMI Study Group BostonMAUnited States Dr.

目的:评价重组线虫抗凝血蛋白c2(rNApc2)治疗非ST段抬高型急性冠状动脉综合征(nSTE-ACS)患者的安全性和有效性。背景:rNApc2是一种组织因子/VⅡa因子复合物的强抑制剂。

关键词：急性冠状动脉综合征 ANThEM-TIMI 32 c2 抗凝血蛋白线虫蠕虫 ST

Storylines of family medicine Ⅰ:framing family medicine–history,values and perspectives

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Family Medicine and Community health 2024年第S03期12卷 2-11页

作者： William B Ventres Leslie A stone Kathleen T Rowland Richard h Streiffer Michael D Macechko Julia A Roulier Jeffrey M Borkan Larry A Green Family and preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family and preventive Medicine Rush Medical College of Rush UniversityChicagoIllinoisUSA College of Community health Sciences University of AlabamaTuscaloosaAlabamaUSA UAMS Northwest Regional Campus Family Medicine Residency program FayettevilleArkansasUSA UAMS North Central Regional Campus Family Medicine Residency program BatesvilleArkansasUSA Family Medicine Brown University Warren Alpert Medical SchoolProvidenceRhode IslandUSA University of Colorado School of Medicine AuroraColoradoUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅰ:framing family medicine—history,values,and perspectives’,the authors address the following themes:‘Notes on Storylines of Family Medicine’,‘Family medicine—the generalist specialty’,‘Family medicine’s achievements—a glass half full assessment’,‘Family medicine’s next 50 years—toward filling our glasses’,‘Four enduring truths of family medicine’,‘Names matter’,‘Family medicine at its core’and‘The ecology of medical care.’May readers find much food for thought in these essays.

关键词： glasses illustration Notes

Storylines of family medicine Ⅲ:core principles—primary care,systems and family

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Family Medicine and Community health 2024年第S03期12卷 23-32页

作者： William B Ventres Leslie A stone Timothy A Joslin John W Saultz Sommer Aldulaimi paul R Gordon John C Lane Eric R Lee Jacob prunuske Limor Gildenblatt Michael h Friedman Colleen T Fogarty Susan h McDaniel Tessa Rohrberg Amy Odom Family and preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medicine Oregon Health&Science UniversityPortlandOregonUSA Family and Community Medicine University of Arizona Medical Center–South CampusTucsonArizonaUSA Family and Community Medicine University of Arizona Medical Center–University CampusTucsonArizonaUSA UAMS West Regional Campus Family Medicine Residency program Fort SmithArkansasUSA Medical College of Wisconsin–Central Wisconsin Campus WausauWisconsinUSA Family and Community Medicine Medical College of Wisconsin–Central Wisconsin CampusWausauWisconsinUSA Family Medicine Advocate Illinois Masonic Medical CenterChicagoIllinoisUSA Family Medicine Presence Saints Mary and Elizabeth Medical CenterChicagoIllinoisUSA Family Medicine University of Rochester Medical CenterRochesterNew YorkUSA psychiatry and Family Medicine University of Rochester Medical CenterRochesterNew YorkUSA Family and Community Medicine University of Kansas School of Medicine-WichitaWichitaKansasUSA Sparrow/Michigan State University Family Medicine Residency program LansingMichiganUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅲ:core principles—primary care,systems,and family’,authors address the following themes:‘Continuity of care—building therapeutic relationships over time’,‘Comprehensiveness—combining breadth and dep.h.of scope’,‘Coordination of care—managing multiple realities’,‘Access to care—intersectional,systemic,and personal’,‘Systems theory—a core value in patient-centered care’,‘Family-oriented practice—supporting patients’health and well-being’,‘Family physician as family member’and‘Family in the exam room’.May readers develop new understandings from these essays.

关键词： individual Storyline principles

内皮剪切应力低的部位即冠状动脉斑块进展和血管重构发生的区域:一项在体连续研究

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世界核心医学期刊文摘（心脏病学分册） 2007年第8期3卷 43-43页

作者： stone p.h. Coskun A.U. Kinlay S. 刘相飞 Department of Medicine Brigham and Women' s Hospital Harvard Medical School 75 Francis Street Boston MA 02115 United States

目的:本研究通过对稳定性冠状动脉疾病(CAD)患者进行一系列血管内检查评估内皮剪切应力(ESS)基线水平、CAD进展及血管重构三者之间的关系。局部血流动力学因素是斑块进展、血管重构和CAD临床表现的重要决定因素。方法和结果:于基线时及8... 详细信息

目的:本研究通过对稳定性冠状动脉疾病(CAD)患者进行一系列血管内检查评估内皮剪切应力(ESS)基线水平、CAD进展及血管重构三者之间的关系。局部血流动力学因素是斑块进展、血管重构和CAD临床表现的重要决定因素。方法和结果:于基线时及8±2个月后,结合冠状动脉内超声及冠状动脉造影对13例患者进行检查,确定管腔阻塞<50%的冠状动脉的三维解剖结构。

关键词：冠状动脉斑块血管重构剪切应力冠状动脉造影基线水平冠状动脉内超声管腔阻塞动力学因素冠状

Monogenic features of urolithiasis: A comprehensive review

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Asian Journal of Urology 2024年第2期11卷 169-179页

作者： Kyo Chul Koo Abdulghafour halawani Victor K.F.Wong Dirk Lange Ben h.Chew Department of Urology Yonsei University College of MedicineSeoulRepublic of Korea Department of Urology King Abdulaziz UniversityJeddahSaudi Arabia Department of Urological Sciences University of British ColumbiaStone Centre at Vancouver General HospitalVancouverBritish ColumbiaCanada

Objective: Urolithiasis formation has been attributed to environmental and dietary factors. however, evidence is accumulating that genetic background can contribute to urolithiasis formation. Advancements in the identification of monogenic causes using high-throughput sequencing technologies have shown that urolithiasis has a strong heritable ***: This review describes monogenic factors implicated in a genetic predisposition to urolithiasis. peer-reviewed journals were evaluated by a pubMed search until July 2023 to summarize disorders associated with monogenic traits, and discuss clinical implications of identification of patients genetically susceptible to urolithiasis ***: Given that more than 80% of urolithiases cases are associated with calcium accumulation, studies have focused mainly on monogenetic contributors to hypercalciuric urolithiases, leading to the identification of receptors, channels, and transporters involved in the regulation of calcium renal tubular reabsorption. Nevertheless, available candidate genes and linkage methods have a low resolution for evaluation of the effects of genetic components versus those of environmental, dietary, and hormonal factors, and genotypes remain undetermined in the majority of urolithiasis ***: The pathophysiology underlying urolithiasis formation is complex and multifactorial, but evidence strongly suggests the existence of numerous monogenic causes of urolithiasis in humans.

关键词： Gene Genetic expression Inheritance pattern Urolithiasis

An inexpensive underwater mine countermeasures simulator with real-time 3D after action review

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Defence Technology（防务技术） 2016年第5期12卷 367-379页

作者： Robert stone Timothy SNELL Neil COOKE human Interface Technologies Team University of Birmingham UK University of Birmingham UK

This paper presents the results of a concept capability demonstration pilot study, the aim of which was to investigate how inexpensive gaming software and hardware technologies could be exploited in the development and evaluation of a simulator prototype for training Royal Navy mine clearance divers, specifically focusing on the detection and accurate reporting of the location and condition of underwater ordnance. The simulator was constructed using the Blender open source 3D modelling toolkit and game engine, and featured not only an interactive 3D editor for underwater scenario generation by instructors, but also a real-time, 3D After Action Review(AAR) system for formative assessment and *** simulated scenarios and AAR architecture were based on early human factors observations and briefings conducted at the UK's Defence Diving School(DDS), an organisation that provides basic military diving training for all Royal Navy and Army(Royal Engineers) divers. An experimental pilot study was undertaken to determine whether or not basic navigational and mine detection components of diver performance could be improved as a result of exposing participants to the AAR system, delivered between simulated diving scenarios. The results suggest that the provision of AAR was accompanied by significant performance improvements in the positive identification of simulated underwater ordnance(in contrast to non-ordnance objects) and on participants' description of their location, their immediate in-water or seabed context and their structural condition. Only marginal improvements were found with participants' navigational performance in terms of their deviation accuracies from a pre-programmed expert search path. Overall, this project contributes to the growing corpus of evidence supporting the development of simulators that demonstrate the value of exploiting open source gaming software and the significance of adopting established games design techniques in delivering highly

关键词： Simulation Virtual reality Diver training Ordnance disposal Mine clearance

Cover Crops as Affecting Soil Chemical and physical properties and Development of Upland Rice and Soybean Cultivated in Rotation

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Rice science 2018年第6期25卷 340-349页

作者： Adriano Stephan NASCENTE Luis Fernando stone Embrapa Arroz e Feij(CNpAF) Rodovia GO-462km 12 Zona RuralCP.17975375-000Santo Antoio de GoiasGOBrasil

Cover crops can provide changes in soil chemical and physical properties, which could allow a sustainable development of soybean and upland rice rotation in Brazilian Cerrado. The objective of this study was to determine the effects of cover crops(cultivated in the offseason) in the soybean-upland rice rotation(cultivated in the summer season) on the soil chemical and physical properties, yield components and grain yield of the cash crops. The experimental design was a randomized block design in factorial scheme 4 × 2 with six replications. Treatments were composed by four cover crops: fallow, millet(pennisetum glaucum) + Crotalaria ochroleuca, millet + pigeon pea(Cajanus cajans), and millet + pigeon pea + Urochola ruziziensis in the offseason with one or two cycles of cover crops, with rice(Oryza sativa)or soybean(Glycine max) in the summer season. Cover crops alone provided no changes in soil chemical properties. however, the rotation cover crops/cash crops/cover crops/cash crops reduced p.h. Al and h + Al and increased Ca, Mg, K and Fe contents in the soil. The cover crops millet + pigeon pea and millet + pigeon pea + U. ruziziensis improved soil physical properties in relation to fallow,especially in the 0–0.10 m soil layer. In spite of the improvement of the soil physical properties after two years of rotation with cover crops and cash crops, the soil physical quality was still below the recommended level, showing values of macroporosity, S index and soil aeration capacity lower than 0.10 m3/m3, 0.035 and 0.34, respectively. Upland rice production was higher under mixtures of cover crops than under fallow, mainly because of soil physical changes done by these mixtures of cover *** grain yield was similar under all cover crops tested, but was higher after the rotation cover crops/upland rice/cover crops than after only one cycle of cover crops.

关键词： crop rotation no-tillage system sustainable agriculture tropical agriculture rice soybean

The training process： planning for strength-power training in track and field. part 1： Theoretical aspects

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Journal of Sport and health Science 2015年第4期4卷 308-317页

作者： Brad h. DeWeese Guy hornsby Meg stone Michael h. stone Exercise and Sport Science Center of Excellence Jor Sport Science and Coach Education East Tennessee State University Johnson City TN 37614 USA Kinesiology and health Sciences Virginia Commonwealth University Richmond VA 23284 USA

The process of strength-power training and the subsequent adaptation is a multi-factorial process. These factors range from the genetics and morphological characteristics of the athlete to how a coach selects, orders, and doses exercises and loading patterns. Consequently, adaptation from these training factors may largely relate to the mode of delivery, in other words, programming tactics. There is strong evidence that the manner and phases in which training is presented to the athlete can make a profound difference in performance outcome. This discussion deals primarily with block periodization concepts and associated methods of programming for strength-power training within track and field. 2015 production and hosting by Elsevier B.V. on behalf of Shanghai University of Sport.

关键词： periodization Strength-power training Track and field Training process

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Efficacy of Tocilizumab in patients hospitalized with Covid-19

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四川生理科学杂志 2021年第1期43卷 98-98页

作者： John h stone From Massachusetts General hospital (J.h.S. M.J.F. N.J.S.-B. A.D.F. L.H. A.S.F. N.K.H. B.C.H. C.A.S. M.D. C.M.N. Y.-D.H. T.K.T. Z.D. A.S. R.S.W. A.Y.K. S.S. P.S. T.G.N. C.A.P. S.H.U. D.S.C. M.A.M. J.M.Y. K.A.B. E.M. A.Z. Z.D.D. M.B.B. M.K. K.M.D. J.D. M.M.L. M.K.M.) Brigham and Women’s Hospital (A.E.W. S.N. B.N.W.) and Boston Medical Center (N.L. M.S.) Boston North Shore Medical Center Salem (R.S. A.M.B. C.C.) Newton-Wellesley Hospital Newton (H.S. D.S.H.) Beth Israel Lahey Health Burlington (M.A. M.D.P.) and St. Elizabeth’s Medical Center Brighton (J.F.) — all in Massachusetts.

Background:The efficacy of interleukin-6 receptor blockade in hospitalized patients with coronavirus disease 2019(Covid-19)who are not receiving mechanical ventilation is ***:We performed a randomized,double-blind,placebo-controlled trial involving patients with confirmed severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,hyperinflammatory states,and at least two of the following signs:fever(body temperature>38℃),pulmonary infiltrates,or the need for supplemental oxygen in order to maintain an oxygen saturation greater than 92%.

关键词： acute respiratory patients

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源于***工作的现代经典物理学

力学进展 2000年第4期30卷 613-621页

作者： M.p. Brenner h.A. stone 李家春黄永念 Department of Mathematics Massachusetts Institute of Technology Cambridge Massachusetts Division of Engineering and Applied Sciences Harvard University Cambridge Massachusetts 中国科学院力学研究所北京大学力学与工程科学系

一位科学家的工作提供了一门完整课程的素材，涉及从流体动力学稳定性、湍流到流体电动力学、微生物的运动．

关键词：流体稳定性湍流统计理论爆炸波旋转流动位错