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Influence of fibre and betaine on development of the gastrointestinal tract of broilers between hatch and 14 d of age

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Animal Nutrition 2019年第2期5卷 163-173页

作者： Tiago T.dos Santos sthéfanie c.dassi celia R.c.Franco cleber R.V.da costa Sophie A.Lee Ana V.Fisher da Silva Universidade Federal do Parana Curtiba81531-900Brazil Department of cell Biology Universidade Federal do ParanaCuritiba81531-900Brazil AB Vista MarlboroughWiltshireSN8 4ANUnited Kindom Department of cell Biology Universidade Federal do ParanaCuritiba81531-900Brazil

An experiment was designed to determine the influence of fibre and betaine on the development of the intestine, liver and pancreas of broilers from hatch to 14 d of age. A total of 250-day-old cobb 500 male broilers were allocated to 16 cages with 15 broilers each. Treatments were arranged in a 2 x 4 factorial design, consisting of 2 feed formulations(low and high fibre diets) and 4 levels of betaine(0,1, 3 or 5 kg/t). At hatch, 10 birds in total were euthanised, and samples of the liver, pancreas, yolk sac and intestine were collected for reference of the analysed parameters before the start of the *** d 4.9 and 14, 5 birds per cage(10 birds per treatment) were selected, euthanised and treated as the same as the birds at hatch. Villus height and width and crypt depth were determined on the duodenum samples, and absorptive area was calculated. The number of enterocytes in mitosis at the villus was determined by a positive reaction to antibody for Ki67 protein, and fused villus was evaluated visually. The relative weight of the yolk sac reduced(P ched a maximum(P creas at d 9. Birds fed the high fibre diet had greater feed intake, lower relative weight of the pancreas and higher villus(P creased(P ciated with fused villus. Betaine inclusion reduced(P creased(P ced(P cytes with positive reaction for the antibody *** inclusion reduced the width and increased the absorptive area and the villus height of the duodenum of birds up to 14 d of age. The higher fibre diet increased feed intake and villus height, yet reduced pancreas relative weight, while not affecting body weight gain. This response was possibly due to a dilution effect of the fibre, reducing nutrient absorption

关键词： Broiler Betaine Fibre Intestine maturation Pancreas Liver

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Neurological Disorders among the Outpatients Living with Human Immuno Deficiency Virus (HIV) Following at the Parakou Hospital in 2014

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Neuroscience & Medicine 2019年第3期10卷 199-206页

作者： Adoukonou Thierry Agbétou Mendinatou dassi Gbénou Jolianelle Ahanhanzo Rhonel Kpangon Arsene Kossi Oyéné Agballa Gottfried Dovonou Albert Houinato Dismand Department of Neurology Faculty of Medicine University of Parakou Parakou Benin Department of Neurology University Departmental Hospital of Parakou Parakou Benin Department of Neurology Faculty of Health Sciences Universitéy of Abomey-Calavi Abomey-Calavi Benin

Objective: To study the frequency of neurological disorders associated to HIV infection. Methods: This cross-sectional study was carried out from 16th June to 16th September 2014 and included all 289 HIV-outpatients admitted to the Parakou University hospital. All data were recorded, physical examination was performed and the medical sheet of each patient was assessed. The diagnosis of neurological disorder (central and peripheral) was based on clinical features, past medical history, biological test and cT-scan data after multidisciplinary staff. Epi-data and Epi-Info 6.04c were used to perform analysis. Results: They were 73 (25.3%) male with a mean age of 38.0 years +/−?10.1 years. The mean duration of disease was 48.5 months +/−37.1 months. 150 (51.9%) of them were at Stage 3 of the disease. All patients (99.7%) were infected by HIV1, 188 (76.1%) had cD4 cells at the onset of the follow-up less than 350 cells/mm3 and 260 (90.0%) were on ART. Among the 289 patients, 110 had at least one neurological disorder, the frequency of neurological disorders was 38.1%. The main neurological disorders were peripheral neuropathy (34.3%), isolated headache (5.2%), stroke (0.7%), cerebral toxoplasmosis (0.7%) and one case of dementia (0.7%). The main associated factors were the age of patient and exposure on neurotoxic drug, especially ART. conclusion: The neurological disorders were more frequent among HIV patients with a high frequency of peripheral neuropathy probably due to ART.

关键词： Neurological Disorders HIV AIDS Peripheral Neuropathy Epidemiology

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