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Neural Regeneration Research 2025年第11期20卷 3179-3192页

作者： Pieter-Jan Serneels Julie D.De Schutter Lies De Groef Lieve Moons steven Bergmans KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionNeural Circuit Development&Regeneration Research GroupLeuvenBelgium KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionCellular Communication&Neurodegeneration Research GroupLeuvenBelgium

Decades of research asserted that the oligodendroglial lineage comprises tw. cell types:oligodendrocyte precursor cells and ***,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing *** forw.rd,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,new.y formed oligodendrocytes,myelin-forming oligodendrocytes,and mature *** new.classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological *** this uniform terminology w.ll facilitate comparison and integration of data across ***,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating ***,comparing injury models across species w.th varying regenerative capacities can provide insights that may lead to new.therapeutic strategies to overcome remyelination ***,by standardizing terminology and synthesizing data from diverse studies across different animal models,w. can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of w.ich involve oligodendroglial and myelin dysfunction.

关键词： animal models demyelination fish mammals multiple sclerosis myelin neurodegeneration oligodendrocytes oligodendroglial lineage remyelination

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亚洲高山流域千年尺度地表剥蚀的制约因素

中国科学:地球科学 2025年第1期 75-94页

作者：杨业 steven A.BINNIE 徐胜刘丛强 Tibor J.DUNAI 天津大学地球系统科学学院表层地球系统科学研究院 Institute of Geology and Mineralogy University of Cologne

本研究利用前人1233个亚洲高山流域沉积物宇宙成因核素10Be数据统一计算了地表剥蚀速率,以约束构造、气候和地形如何影响和控制地表剥蚀过程.基于高程数据逐个像元的核素产率,使用蒙特卡洛模拟方法重新计算了10Be流域剥蚀速率.剥蚀速率... 详细信息

本研究利用前人1233个亚洲高山流域沉积物宇宙成因核素10Be数据统一计算了地表剥蚀速率,以约束构造、气候和地形如何影响和控制地表剥蚀过程.基于高程数据逐个像元的核素产率,使用蒙特卡洛模拟方法重新计算了10Be流域剥蚀速率.剥蚀速率变化范围从（7.4±0.7）mm ka-1（1σ;青藏高原内部）到（9,646744+777）mm ka-1（1σ;青藏高原南部）跨四个数量级,中位数为186mm ka-1.逐个像元计算的核素产率与传统模型使用质心坐标和平均高程计算的核素产率相比,后者96.6%核素产率被低估,其中高程差越大越被低估.两种方法计算的产率偏差可达40%,究其原因可能是流域高程分布不均和核素产率随海拔和纬度呈非线性变化.通过量化地表剥蚀速率与构造、气候、地形和岩性之间的相关性将有助于推演未知流域的剥蚀速率.从局部小尺度分析,亚热带台湾岛地区剥蚀速率可能主要受降水和新构造驱动的山体滑坡影响,而降水变化范围较窄的青藏高原东部的剥蚀速率主要受控于地形;冰川覆盖的高原地区剥蚀速率受冰川作用影响,如帕米尔、青藏高原内部和南部地区;青藏高原内部剥蚀速率较低是因为较低的降水和较高的侵蚀基准面,从而限制了河流的下切和地表起伏度演化.与局部小尺度强调单一主控因素不同,本研究对亚洲高山流域宏观大尺度进行量化分析发现:（1）地形指标（包括坡度、地形起伏度和河道陡峭指数）与剥蚀速率在千年尺度呈现一致的幂函数关系,而非简单线性;（2）剥蚀速率与气候（包括与海拔相关的降水、温度和植被覆盖度）和新构造活动（地震核密度分布）呈近似幂函数关系,为次要控制因素;（3）岩性与剥蚀速率没有明显的相关性,可能受限于流域复杂的岩性混合和低分辨率的可侵蚀指数数据.

关键词： 10Be剥蚀速率气候变化构造抬升地形梯度亚洲高山流域

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Headw.ter regions- Physical, ecological, and social approaches to understand these areas： introduction to the special issue

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Frontiers of Earth Science 2017年第3期11卷 443-446页

作者： steven R. FASSNACHT Ryan w. w.BB w.lliam E. SANFORD ESS-w.tershed Science Colorado State University Fort Collins CO 80523-1476 USA Geographisches Institut Abt. Kartographie GIS & Femerkundung Georg-August-Universitat Gottingen 37077 Gottingen Germany Cooperative Institute for Research in the Atmosphere Fort Collins CO 80523-1375 USA Geospatial Centroid Colorado State University Fort Collins CO 80523-1101 USA Natural Resources Ecology Laboratory Fort Collins CO 80523-1499 USA Institute of Arctic and Alpine Research University of Colorado Boulder Boulder CO 80309-0450 USA Geosciences Colorado State University Fort Collins CO 80523-1482 USA

Around the w.rld human communities and natural ecosystems both rely on headw.ter regions for vital resources. Resources provided include groundw.ter sto- rage （Flint et al., 2008; Clilverd et al., 2011; Cao et al., 2012） in addition to soil moisture and forest ecosystem dynamics （McNamara et al., 2005; w.lliams et al., 2009; Jencso and McGlynn, 2011; Smith et al., 2011; Harpold et al., 2015; w.bb et al., 2015）. Furthermore these regions are ecologically vital zones （Schlosser, 1995; Low. and Likens, 2005） that impact dow.stream w.ter quality （Peterson et al., 2001; Alexander et al., 2007）.

关键词： Social behavior Headw.ters

Supercritical fluids:Clean solvents for green chemistry

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Chinese Journal of Chemistry 1999年第3期17卷 212-222,201页

作者： POLIAKOFF Martyn GEORGE Michael w. HOw.LE steven M. BAGRATASHVILI Viktor N. 韩布兴闫海科 LaserChem Scientific Centre for Technological Lasers of the Russian Academy of Sciences Troitzk (Moscow Region) Institute of Chemistry Chinese Academy of Sciences Beijing 100080 China Department of Chemistry The University of Nottingham Nottingham NG7 2RD England

Supercritical fluids are becoming increasingly attractive as environmentally acceptable replacement for organic solvents in chemical reactions and material processing. This paper highlights some of the properties of supercritical fluids, especially supercritical CO2, w.ich offer particular advantages for the handling of polymers, metal complexes and the environmentally more friendly synthesis and manufacture of chemicals. The paper includes same of the researches in University of Nottingham and a number of recent review. w.ich together provide a comprehensive introduction.

关键词： Green chemistry supercritical fluids chemical reaction w.ter rapid expansion antisolvent

Cyber Attack Protection and Control of Microgrids

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IEEE/CAA Journal of Automatica Sinica 2018年第2期5卷 602-609页

作者： Md Masud Rana Li Li steven w.Su Faculty of Engineering and Information Tech- nology University of Technology Sydney Broadway NSW 2007 Australia

Recently, the smart grid has been considered as a next-generation pow.r system to modernize the traditional grid to improve its security, connectivity, efficiency and ***, the smart grid is susceptible to malicious cyber attacks, w.ich can create serious technical, economical, social and control problems in pow.r netw.rk operations. In contrast to the traditional cyber attack minimization techniques, this paper proposes a recursive systematic convolutional(RSC) code and Kalman filter(KF) based method in the context of smart ***, the proposed RSC code is used to add redundancy in the microgrid states, and the log maximum a-posterior is used to recover the state information, w.ich is affected by random noises and cyber attacks. Once the estimated states are obtained by KF algorithm, a semidefinite programming based optimal feedback controller is proposed to regulate the system states, so that the pow.r system can operate properly. Test results show.that the proposed approach can accurately mitigate the cyber attacks and properly estimate and control the system states.

关键词： Index Terms--Cyber attack Kalman filter (KF) optimal feed-back control renew.ble microgrid smart grid.

Non-genetic contributions of the sperm nucleus to embryonic development

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Asian Journal of Andrology 2011年第1期13卷 31-35页

作者： Yasuhiro Yamauchi Jeffrey A Shaman w.steven w.rd Department Anatomy and Reproductive Biology Institute for Biogenesis Research John A. Burns School of Medicine University of Hawaii at Manoa Honolulu HI USA GLP Services GENEWlZ Inc. 115 Corporate Blvd. South Plainfield NJ 07080 USA

Recent data from several laboratories have provided evidence that the new.y fertilized oocyte inherits epigenetic signals from the sperm chromatin that are required for proper embryonic development. For the purposes of this review. the term epigenetic is used to describe all types of molecular information that are transmitted from the sperm cell to the embryo. There are at least six different forms of epigenetic information that have already been established as being required for proper embryogenesis in mammals or for w.ich there is evidence that it may do so. These are （i） DNA methylation; （ii） sperm-specific histones, （iii） other chromatin-associated proteins; （iv） the perinuclear theca proteins; （v） sperm-born RNAs and, the focus of this review. and （vi） the DNA loop domain organization by the sperm nuclear matrix. These epigenetic signals should he considered w.en designing protocols for the manipulation and cryopreservation of spermatozoa for assisted reproductive technology as necessary components for effective fertilization and subsequent embryo development.

关键词： embryogenesis epigenetics sperm DNA sperm nuclear matrix DNA loop domain organization

Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention

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Protein & Cell 2011年第9期2卷 691-695页

作者： w.nisa Salaemae Al Azhar Grant w.Booker steven w.Polyak School of Molecular and Biomedical Sciences University of AdelaideSouth Australia 5005Australia

Biotin is an important micronutrient that serves as an essential enzyme *** obtain biotin either through de novo synthesis or by active uptake from exogenous *** are unusual amongst bacteria in that their primary source of biotin is through de novo *** w. review.the importance of biotin biosynthesis in the lifecycle of *** screens designed to identify key metabolic processes have highlighted a role for the biotin biosynthesis in bacilli grow.h,infection and survival during the latency *** studies help to establish the biotin biosynthetic pathw.y as a potential drug target for new.anti-tuberculosis agents.

关键词： synthesis. phase. synthesis

Myxomycetes associated w.th grasslands of the w.stern central United States

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Fungal Diversity 2013年第2期59卷 147-158页

作者： Adam w.Rollins steven L.Stephenson Department of Biology Lincoln Memorial UniversityHarrogateTN 37752USA Department of Biological Sciences University of ArkansasFayettevilleAR 72701USA

The assemblages of myxomycetes associated w.th the three types of temperate grasslands(tall grass,mixed grass and short grass)found across the w.stern central United States w.re examined by collecting samples for isolation of these organisms from nine study *** consisted of tw. types of ground litter,tw. types of aerial litter(dead but still attached plant parts)and *** w.re brought back to the laboratory and used to prepare a series of moist chamber *** cultures yielded 1,301 collections of myxomycetes representing 59 species in 18 *** collections could be identified only to genus and one in particular(Lepidoderma sp.)appears to be an undescribed *** spectabile w.s recorded for the first time in North ***,only eight species(Badhamia melanospora,Didymium anellus,***,***,Perichaena depressa,Physarum cinereum,***,and Stemonitis fusca)w.re recovered from all nine study sites and thus are considered to represent a core component of the myxomycete biota of temperate grasslands.

关键词： Community ecology Ecological distribution Grasslands Microhabitat Myxogastrids

Response of Microcystis aeruginosa FACHB-905 to different nutrient ratios and changes in phosphorus chemistry

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Journal of Oceanology and Limnology 2018年第4期36卷 1040-1052页

作者： PENG Guotao steven w.w.LHELM LIN Sijie w.NG Xlangrong College of Environmental Science and Engineering State Key Laboratory of Pollution Control and Resource ReuseTongj UniversityShanghai 200092China Department of Environmental Science and Engineering Fudan UniversityShanghai 200433China Department of Microbiology University of TennesseeKnoxvilleTN37920USA

Cyanobacterial blooms are a global problem, w.th their occurrence tightly tied to nutrient loading. w. cultured Microcystis aeruginosa FACHB-905 in grow.h medium w.th either inorganic(orthophosphate) or organic(β-glycerophosphate or polyphosphate) phosphorus and at different N:P ratios w.th 50:1, 30:1, 16:1, 4:1 and 1:4, serving as the phosphorus source. Fluorescence parameters w.re measured to determine the response of cellular responses to nutrient stress. Scanning electron microscopy(SEM) and estimates of antioxidant activity w.re employed to examine potential mechanisms of physical change. The results demonstrate that inorganic phosphorus w.s more bioavailable to M. aeruginosa relative to organic phosphorus in culture. The highest cell concentration(2.21×10~6 cells/mL), chlorophyll-a(0.39 pg/cell) and phycocyanin(1.57 pg/cell) quotas and high levels of chlorophyll fluorescence parameters( rETR, E_k, α, φ_(PSⅡ) and F_v/F_m) w.re obtained w.en phosphorus w.s supplied as K_2 HPO_4 at a N:P ratio of 16–30. Organic sources of phosphorus(β-glycerophosphate and polyphosphate) w.re bioavailable to M. aeruginosa. In addition, too concentrated orthophosphate(N:P=1:4) resulted in the oxidative stress and lipid peroxidation of cell membrane(identified by the antioxidant system activity), and the photosynthetic activity declined consequently. This study has demonstrated the effects of different phosphorus chemistries and N:P ratios on the cyanobacterial grow.h, photosynthetic activity and cell physiology, w.ich could be an effective tool for predicting cyanobacterial dominance or N-deficiency in natural lakes(due to the superior ability of cyanobacteria for dissolved N and fix atmospheric N in some cases).

关键词： antioxidant system chlorophyll fluorescence parameters Microcystis nutrient stress photosynthesis