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An Interpretable Artificial Intelligence Based Smart Agriculture System

Computers, Materials & Continua 2022年第8期72卷 3777-3797页

作者： Fariza Sabrina Shaleeza Sohail Farnaz Farid Sayka Jahan Farhad Ahamed steven gordon School of Engineering and Technology Central Queensland UniversitySydneyAustralia College of Engineering Science and EnvironmentThe University of NewcastleSydneyAustralia School of Social Sciences Western Sydney UniversitySydneyAustralia Department of Environmental Sciences Macquarie UniversitySydneyAustralia School of Computing Data and MathematicalSciencesWestern Sydney UniversitySydneyAustralia School of Engineering and Technology Central Queensland UniversityCairnsAustralia

With increasing world population the demand of food production has increased *** of Things(IoT)based smart agriculture system can play a vital role in optimising crop yield by managing crop requirements in *** can be an important factor to make such systems trusted and easily adopted by *** this paper,we propose a novel artificial intelligence-based agriculture system that uses IoT data to monitor the environment and alerts farmers to take the required actions for maintaining ideal conditions for crop *** strength of the proposed system is in its interpretability which makes it easy for farmers to understand,trust and use *** use of fuzzy logic makes the system customisable in terms of types/number of sensors,type of crop,and adaptable for any soil types and weather *** proposed system can identify anomalous data due to security breaches or hardware malfunction using machine learning *** ensure the viability of the system we have conducted thorough research related to agricultural factors such as soil type,soil moisture,soil temperature,plant life cycle,irrigation requirement and water application timing for Maize as our target *** experimental results show that our proposed system is interpretable,can detect anomalous data,and triggers actions accurately based on crop requirements.

关键词： Explainable artificial intelligence fuzzy logic internet of things machine learning sensors smart agriculture

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Methane Emissions from Grazing Holstein-Friesian Heifers at Different Ages Estimated Using the Sulfur Hexafluoride Tracer Technique

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Engineering 2017年第5期3卷 753-759页

作者： steven J. Morrisonn Judith McBride Alan W. gordon Alastair R. G. Wylie Tianhai Yan Agri-Food and Biosciences Institute Hillsborough County Down BT26 6DR UK Agri-Food and Biosciences Institute Belfast BT9 5PX UK

Although the effect of animal and diet factors on enteric methane （CH4） emissions from confined cattle has been extensively examined, less data is available regarding CH4 emissions from grazing young cattle. A study was undertaken to evaluate the effect of the physiological state of Holstein-Friesian heifers on their enteric CH4 emissions while grazing a perennial ryegrass sward. Two experiments were conducted： Experiment 1 ran from May 2011 for 11 weeks and Experiment 2 ran from August 2011 for 10 weeks. In each experiment, Holstein-Friesian heifers were divided into three treatment groups （12 animals/group） consisting of calves, yearling heifers, and in-calf heifers （average ages： 8.5, 14.5, and 20.5 months, respectively）. Methane emissions were estimated for each animal in the final week of each experiment using the sulfur hexafluoride tracer technique. Dry matter （DM） intake was estimated using the calculated metabolizable energy （ME） requirement divided by the ME concentration in the grazed grass. As expected, live weight increased with increasing animal age （P 〈 0.001）; however, there was no difference in live weight gain among the three groups in Experiment 1, although in Experiment 2, this variable decreased with increasing animal age （P 〈 0.001 ）. In Experiment 1, yearling heifers had the highest CH4 emissions （g·d^-1） and in-calf heifers produced more than calves （P 〈 0.001 ）. When expressed as CH4 emissions per unit of live weight, DM intake, and gross energy （GE） intake, yearling heifers had higher emission rates than calves and in-calf heifers （P 〈 0.001）. However, the effects on CH4 emissions were different in Experiment 2, in which CH, emissions （g·d^-1） increased linearly with increasing animal age （P 〈 0.001）, although the difference between yearling and in-calf heifers was not significant. The CH4/live weight ratio was lower in in-calf heifers than in the other two groups （P 〈 0.001 ）, while CH4 energy output as a proportion of GE intake was lower

关键词： Methane emission Grazing dairy heifer Prediction Sulfur hexafluoride tracer technique

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Profiling of immune features to predict immunotherapy efficacy

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The Innovation 2022年第1期3卷 71-82页

作者： Youqiong Ye Yongchang Zhang Nong Yang Qian Gao Xinyu Ding Xinwei Kuang Rujuan Bao Zhao Zhang Chaoyang Sun Bingying Zhou Li Wang Qingsong Hu Chunru Lin Jianjun Gao Yanyan Lou steven HLin Lixia Diao Hong Liu Xiang Chen gordon B.Mills Leng Han Shanghai Institute of Immunology Department of Immunology and MicrobiologyShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Biochemistry and Molecular Biology The University of Texas Health Science Center at Houston McGovern Medical SchoolHoustonTX 77030USA Department of Medical Oncology Lung Cancer and Gastrointestinal UnitHunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of MedicineCentral South UniversityChangshaHunan 410008China Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunan 410008China Department of Obstetrics and Gynecology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China State Key Laboratory of Cardiovascular Disease Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100037China Department of Molecular and Cellular Oncology The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Department of Genitourinary Medical Oncology The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Division of Hematology and Oncology Mayo ClinicJacksonvilleFL 32224USA Department of Radiation Oncology Division of Radiation OncologyThe University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Department of Bioinformatics and Computational Biology The University of Texas MD Anderson Cancer CenterHoustonTX 77030USA Knight Cancer Institute Oregon Health and Science UniversityPortlandOR 97239USA Center for Epigenetics and Disease Prevention Institute of Biosciences and TechnologyTexas A&M UniversityHoustonTX 77030USA Department of Translational Medical Sciences College of MedicineTexas A&M UniversityHoustonTX 77030 USA

Immune checkpoint blockade(ICB)therapies exhibit substantial clinical benefit in different cancers,but relatively low response rates in the majority of patients highlight the need to understand mutual relationships among immune ***,we reveal overall positive correlations among immune checkpoints and immune cell ***,patients benefiting from ICB exhibited increases for both immune stimulatory and inhibitory features after initiation of therapy,suggesting that the activation of the immune microenvironment might serve as the biomarker to predict immune *** proof-of-concept,we demonstrated that the immune activation score(ISD)based on dynamic alteration of interleukins in patient plasma as early as two cycles(4-6 weeks)after starting immunotherapy can accurately predict immunotherapy *** results reveal a systematic landscape of associations among immune features and provide a noninvasive,cost-effective,and time-efficient approach based on dynamic profiling of pre-and on-treatment plasma to predict immunotherapy efficacy.

关键词： immunotherapy features mutual

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SUPPRESSOR OF VARIEGATION4, a New var2 Suppressor Locus, Encodes a Pioneer Protein that Is Required for Chloroplast Biogenesis

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Molecular Plant 2011年第2期4卷 229-240页

作者： Fei Yu ung-Soon Park Xiayan Liu Andrew Foudree Aigen Fu Marta Powikrowska Anastassia Khrouchtchova Poul Erik Jensen Jillian N. Kriger gordon RI Gray steven R. Rodermel College of Life Sciences Northwest A&F University Yangling Shaanxi 712100 People's Republic of China Department of Plant and Microbial Biology University of California Berkeley Berkeley CA 94720 USA Department of Genetics Development and Cell Biology iowa State University 253 Bessey Hall Ames IA 50011 USA Department of Plant Biology and Biotechnology Faculty of Life Sciences University of Copenhagen Thorvaldsensvej 40 DK-1871 Frederiksberg C Denmark Department of Plant Sciences University of Saskatchewan Saskatoon Saskatchewan S7N 5A8 Canada

VAR2 is an integral thylakoid membrane protein and a member of the versatile FtsH class of metalloproteases in prokaryotes and eukaryotes. Recessive mutations in the VAR2 locus give rise to variegated plants （var2） that contain white sectors with abnormal plastids and green sectors with normal-appearing chloroplasts. In a continuing effort to isolate second-site suppressors of var2 variegation, we characterize in this report ems2505, a suppressor strain that has a virescent phenotype due to a missense mutation in At4g28590, the gene for a pioneer protein. We designated this gene SVR4 （for SUPPRESSOR OF VARIEGATION4） and the mutant allele in ems2505 as svr4-1. We demonstrate that SVR4 is located in chloroplasts and that svr4-1 single mutants are normal with respect to chloroplast anatomy and thylakoid membrane protein accumulation. However, they are modestly impaired in several aspects of photochemistry and have enhanced non-photochemical quenching （NPQ） capacity. A T-DNA insertion allele of SVR4, svr4-2, is seedling-lethal due to an early blockage of chloroplast development. We conclude that SVR4 is essential for chloroplast biogenesis, and hypothesize that SVR4 mediates some aspect of thylakoid structure or function that controls NPQ. We propose that in the suppressor strain, photoinhibitory pressure caused by a lack of VAR2 is ameliorated early in chloroplast development by enhanced NPQ capacity caused by reduced SVR4 activity. This would result in an increase in the number of chloroplasts that are able to surmount a threshold necessary to avoid photo-damage and thereby develop into functional chloroplasts.

关键词： Arabidopsis chloroplast biogenesis non-photochemical quenching (NPQ) photo-damage suppressor strain variegation

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猪Ⅱ型圆环病毒对现代养猪生产的重大影响

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养猪进展 2006年第1期 15-17页

作者： steven Krakowka John Ellis Francis McNeilly gordon Allan Department of Veterinary Biosciences College of Veterinary Medicine Ohio State University Western College of Veterinary Medicine University of Saskatchewan Saskatoon Canada Department of Agriculture and Rural Development Veterinary Sciences Division Belfast Northern Ireland

由于感染了猪Ⅱ型圆环病毒的疾病的范围已有所扩大，那些能加重疾病发展的感染辅助因子现已成为研究热点。本文综述了猪Ⅱ型圆环病毒对现代养猪生产的重大影响。

关键词：猪Ⅱ型圆环病毒现代养猪生产辅助因子疾病感染

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Ⅱ型猪圆环病毒——滴答作响的定时炸弹?

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国外畜牧学（猪与禽） 2003年第2期23卷 47-49页

作者：李希林 gordon Allan steven Krakowka John Ellis 北爱尔兰农业和乡村发展部美国俄亥俄州立大学兽医学院兽医生物科学系加拿大萨斯卡彻温医科大学

对Ⅱ型猪圆环病毒的研究为与猪断奶后多系统消耗性综合征在全球爆发有关的问题提供了大量答案,但还有一些方面迫切需要引起人们的关注,以便为可能出现的梦魇般的前景准备对策。

关键词： Ⅱ型猪圆环病毒猪断奶后多系统消耗性综合征遗传病原

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Rothman Simeone The Spine 6Th Edition

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2011年

作者： Herkowitz, Harry N. Garfin, steven R. Eismont, Frank J. Bell, gordon R. Balderston, Richard A.

ISBN: (纸本)9781416067269

Rothman-Simeone The Spine helps you achieve optimal outcomes in the clinical practice of spine surgery in adults and children. Drs. Harry N. Herkowitz, steven R. Garfin, Frank J. Eismont, gordon R. Bell, Richard Balderston, and an internationally diverse group of authorities help you keep up with the fast-paced field and get the best results from state-of-the-art treatments and surgical techniques, such as spinal arthroplasty and the latest spinal implants and equipment. An all-new full-color design and surgical videos on DVD and online at *** make this classic text more invaluable than ever before. Get the best results from the full range of both surgical and non-surgical treatment approaches with guidance from the world's most trusted authorities in orthopaedic spine surgery. Find important information quickly through pearls, pitfalls, and key points that highlight critical points. Watch experts perform key techniques in real time with videos, on DVD and online, demonstrating minimally invasive surgery: SED procedure; thorascopic techniques; lumbar discectomy; pedicle subtraction osteotomy (PSO); C1, C2 fusion; intradural tumor; cervical laminoforaminoty; and much more. Apply the newest developments in the field thanks to expert advice on minimally invasive surgery, spinal arthroplasty and the latest spinal implants and equipments. See procedures clearly through an all new full-color design with 2300 color photographs and illustrations placed in context. Access the fully searchable contents of text online at ***. The new edition of the leading spine book in the fast-paced field of spine surgery presents state-of-the-art treatments and surgical techniques for spinal disorders through text and videos and is written by an internationally diverse group of the best specialist surgeons.

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自发性脑出血管理指南美国心脏协会／美国卒中协会针对医疗专业人员的指南

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国际脑血管病杂志 2015年第10期23卷 721-739页

作者： J. Claude Hemphill Ⅲ steven M. Greenberg Craig S. Anderson Kyra Beckelr Bernard R. Bendok Mary Cushman gordon L. Fung Joshua N. Goldstein R. LochMacdonald Pamela H Mitchell, Phillip A Scott,Magdy H Selim, Daniel Woo 高圆圆徐欣不详南京大学医学院附属鼓楼医院神经内科 210008

目的本指南旨在为自发性脑出血的诊断和治疗提供最新的全面推荐意见。方法利用PubMed进行规范化文献检索，检索时间至2013年8月底。撰写委员会成员通过远程电信会议讨论指南内容及推荐意见，采用美国心脏协会／美国卒中协会的疗效确定... 详细信息

目的本指南旨在为自发性脑出血的诊断和治疗提供最新的全面推荐意见。方法利用PubMed进行规范化文献检索，检索时间至2013年8月底。撰写委员会成员通过远程电信会议讨论指南内容及推荐意见，采用美国心脏协会／美国卒中协会的疗效确定性水平和证据分级方案对推荐意见进行分级。由6位同行评议专家以及卒中委员会科学声明监督委员会和卒中委员会领导委员会成员对指南草案进行发表前审阅。结果本文为急性脑出血患者的医疗诊治提供了循证指南，重点包括诊断、凝血功能障碍和血压管理、继发性脑损伤防治、颅内压控制、外科治疗的作用、转归预测、康复、二级预防以及将来需要考虑的问题。本指南已纳入最新的3期临床试验结果。结论脑出血是一种需要进行早期积极救治的危重疾病。本指南为脑出血患者的目标导向治疗提供了一个框架。

关键词：美国心脏协会科学声明血压凝血功能障碍诊断脑出血脑室出血外科手术治疗

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在临床研究中,索磷布韦/维帕他韦用于伴随使用质子泵抑制剂的患者时安全有效

在临床研究中,索磷布韦/维帕他韦用于伴随使用质子泵抑制剂的患者...

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第十届全国疑难及重症肝病大会

作者： Rafael Esteban Kosh Agarwal Jose Luis Calleja Jean Francois Dufour steven L.Flamm Stuart C.gordon Luisa Stamm Liyun Ni Diana Brainard Kris V.Kowdley Curtis Cooper Juan Antonio Pineda Lluis Castells Maria Buti Sabela Lens UniversityofBarcelona SwedishMedicalCenter GileadSciencesInc. HospitalUniversitariValld’Hebron GileadSciences Inc. VallD’hebronUniversityHospital NorthwesternUniversityHealthSystem HospitalUniversitarioPuertaDeHierro HospitalUniversitarioVirgenDeValme UniversityofBern LiverUnit InternalMedicineDepartmentHospitalUniversitariVallDeHebrón InstituteofLiverStudies King’sCollegeHospitalNHSTrust HenryFordHealthSystem TheOttawaHospital

背景在1期药物相互作用数据可用之前,在有关索磷布韦/维帕他韦(SOF/VEL)的临床试验中禁止伴随使用质子泵抑制剂(PPI)。之后的临床研究允许使用最多20mg的奥美拉唑或等效剂量的药物。本分析评估了接受12周的SOF/VEL治疗并且报告伴随使用...

背景在1期药物相互作用数据可用之前,在有关索磷布韦/维帕他韦(SOF/VEL)的临床试验中禁止伴随使用质子泵抑制剂(PPI)。之后的临床研究允许使用最多20mg的奥美拉唑或等效剂量的药物。本分析评估了接受12周的SOF/VEL治疗并且报告伴随使用PPI的伴有和不伴有代偿期肝硬化的患者的疗效和安全性。

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