检索结果-南通市图书馆

World Journal of Gastroenterology 2018年第28期24卷 3101-3111页

作者： Christopher J Danford steven C lin Martin P Smith Jacqueline l Wolf Division of Gastroenterology and Hepatology Beth Israel Deaconess Medical Center Harvard Medical School Department of Radiology Beth Israel Deaconess Medical Center Harvard Medical School

Encapsulating peritoneal sclerosis(EPS) is a debilitating condition characterized by a fibrocollagenous membrane encasing the small intestine, resulting in recurrent small bowel obstructions. EPS is most commonly associated with long-term peritoneal dialysis, though medications, peritoneal infection, and systemic inflammatory disorders have been implicated. Many cases remain idiopathic. Diagnosis is often delayed given the rarity of the disorder combined with non-specific symptoms and laboratory findings. Although cross-sectional imaging with computed tomography of the abdomen can be suggestive of the disorder, many patients undergo exploratory laparotomy for diagnosis. Mortality approaches 50% one year after diagnosis. Treatment for EPS involves treating the underlying condition or eliminating possible inciting agents(i.e. peritoneal dialysis, medications, infections) and nutritional support, frequently with total parenteral nutrition. EPSspecific treatment depends on the disease stage. In the inflammatory stage, corticosteroids are the treatment of choice, while in the fibrotic stage, tamoxifen may be beneficial. In practice, distinguishing between stages may be difficult and both may be used. Surgical intervention, consisting of peritonectomy and enterolysis, is timeconsuming and high-risk and is reserved for situations in which conservative medical therapy fails in institutions with surgical expertise in this area. Herein we review the available literature of the etiology, pathogenesis, diagnosis, and treatment of this rare, but potentially devastating disease.

关键词： Abdominal cocoon Sclerosing encapsulating peritonitis Peritoneal sclerosis Peritonectomy Enterolysis Peritoneal dialysis Tamoxifen Corticosteroids

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neochaetosphaerella thaxteriospora *** *** Tympanopsis texensis ***.(Coronophorales,Ascomycota)from Texas,USA

引用

Fungal Diversity 2012年第1期52卷 191-196页

作者： larissa N.Vasilyeva Aleksey V.Chernyshev steven l.Stephenson Institute of Biology and Soil Sciences Far East Branch of the Russian Academy of SciencesVladivostokRussia A.V.Zhirmunsky Institute of Marine Biology Far East Branch of the Russian Academy of SciencesVladivostokRussia Department of Biological Sciences University of ArkansasFayettevilleAR 72701USA

Ascomata of three species of coronophoraceous fungi collected from the Big Thicket National Preserve and an area immediately adjacent to the preserve were examined with a scanning electron microscope to reveal the distinctive features of the ascomatal *** on the results of the examination,two new species(Neochaetosphaerella thaxteriospora and Tympanopsis texensis)are herein described and *** a description and an illustration of Scortechinia acanthostroma are also provided.

关键词： Coronophoraceous fungi Neochaetosphaerella Scortechinia Tympanosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Principles of Clinical Cytogenetics 2nd ed. 2005

引用

2005年

作者： steven l. Gersen Martha B. Keagle

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

The Role of RNA Epitranscriptomics and the RNA Fat Mass and Obesity-Associated Demethylase in Triple Negative Breast Cancer

引用

Advances in Breast Cancer Research 2023年第2期12卷 27-50页

作者： Emilija Sagaityte Richard S. Dowd Kendall lane Stephanie l. Graff steven A. Toms Department of Neurosurgery Warren Alpert School of Medicine Brown University Providence USA Department of Neurosurgery Rhode Island Hospital Lifespan Health System Providence USA lifespan Cancer Institute Rhode Island Hospital Legorreta Cancer Center at Brown University Providence USA

Breast cancer is one of the most commonly diagnosed cancers and one of the most significant sources of cancer mortality. Triple negative breast cancer (TNBC) is a particularly aggressive subtype that has proven difficult to treat with standard chemotherapies. Obesity has also been shown to exacerbate breast cancer, and diagnoses of these two diseases frequently overlap. Both conditions are regulated in part by the fat mass and obesity-associated (FTO) demethylase, an RNA demethylase which may drive breast cancers through epigenetic alterations to gene expression. Methods of inhibiting FTO have been researched in vitro and in vivo as an alternative or adjunct to chemotherapies in multiple cancers, including breast cancer. Translating knowledge of the role of FTO in breast cancer and the development of novel agents may allow for improvements in the treatment of this refractory cancer. This review therefore aims to provide an overview of existing and developing chemical inhibitors of FTO that could be innovatively studied for the treatment of TNBC and associated comorbidity.

关键词： Breast Cancer Obesity Fat Mass and Obesity-Associated Chemotherapy Ep-igenetics RNA

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Active learning of deep surrogates for PDEs:application to metasurface design

引用

npj Computational Materials 2020年第1期6卷 312-318页

作者： Raphaël Pestourie Youssef Mroueh Thanh V.Nguyen Payel Das steven G.Johnson Department of Mathematics Massachusetts Institute of Technology77 Massachusetts AveCambridgeMA 02139USA IBM Research AI IBM Thomas J Watson Research CenterYorktown HeightsYorktownNY 10598USA MIT-IBM Watson AI lab CambridgeMA 02139USA Iowa State University AmesIA 50011USA

Surrogate models for partial differential equations are widely used in the design of metamaterials to rapidly evaluate the behavior of composable ***,the training cost of accurate surrogates by machine learning can rapidly increase with the number of *** photonic-device models,we find that this training becomes especially challenging as design regions grow larger than the optical *** present an active-learning algorithm that reduces the number of simulations required by more than an order of magnitude for an NN surrogate model of optical-surface components compared to uniform random *** show that the surrogate evaluation is over two orders of magnitude faster than a direct solve,and we demonstrate how this can be exploited to accelerate large-scale engineering optimization.

关键词： optimization surrogate faster

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World politics in a new era. 3rd ed. /

World politics in a new era.

引用

2004年

作者： l, stevenSpiegel, steven l.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Biodiversity studies of myxomycetes in Madagascar

引用

Fungal Diversity 2013年第2期59卷 55-83页

作者： Diana Wrigley de Basanta Carlos lado Arturo Estrada-Torres steven l.Stephenson Real Jardín Botánico CSICPlaza de Murillo228014 MadridSpain Centro de Investigación en Ciencias Biológicas Universidad Autónoma de TlaxcalaApartado Postal 183Tlaxcala 90000 TlaxcalaMexico Department of Biological Sciences University of ArkansasFayettevilleAR 72701USA

The results of the first comprehensive study of myxomycetes from the island of Madagascar,a world biodiversity hotspot,are reported in this *** island is of continental origin,the fourth largest in the world,and has been geographically isolated for more than 160 million years,since its separation from *** isolation,size and topography of Madagascar have triggered the development of a great variety of different habitats and favoured multiple evolutionary pathways,resulting in many animals and plants that exist nowhere else on *** for the biodiversity survey of the central and southern parts of the island took place in May 2009,to coincide with the end of the rainy *** moist forest,sclerophyll forest and dry forest were selected for sampling in Ranomafana,Andringitra,Andohahela and l’Isalo National *** unique vegetation was sampled in the spiny dry forest and succulent scrub with plants from the genera Alluaudia,Euphorbia,Kalanchoe and *** survey produced 124 species from 22 different genera in more than 750 myxomycete *** this paper one species,Perichaena madagascariensis,is described as new to science,21 species are new records for Africa,and 106 are reported for the first time from *** unusual collections included Physarum lakhanpalii that appeared on Ravenala madagascariensis,Fuligo intermedia and licea nannengae found on Adansonia grandidieri,Perichaena pulcherrima,Physarum dictyosporum,and *** on Euphorbia and licea rufocuprea on *** scope,methods and results of this survey are included in this paper,and comments are made on the ecology,distribution and substrate association of the myxomycetes of these areas of ***,micrographs and SEM images of interesting species are *** results indicate that the island of Madagascar has a unique assemblage of species of myxomycetes,different from neighbouring islands and from similar but distant envi

关键词： Amoebozoa Biogeography Endemism Myxogastria SEM Spiny forest

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Survey of Unbalanced Flow Diagnostics and Their Application

引用

Advances in Atmospheric Sciences 2000年第2期17卷 165-183页

作者： Fuqing Zhang steven E. Koch Christopher A. Davis and Michael l. Kaplan Department of Marine Earth and Atmospheric Sciences North Carolina State University Raleigh USA National Center for Atmospheric Research Boulder USA

This paper presents an extensive survey of the most commonly used tools for diagnosing unbalanced flow in the atmosphere, namely the lagrangian Rossby number, Psi vector, divergence equation, nonlinear balance equation, generalized omega-equation, and departure from fields obtained by potential vorticity (PV) inversion. The basic thoery, assumptions as well as implementation and limitations for each of the tools are all discussed. These tools are applied to high—resolution mesoscale model data to assess the role of unbalanced dynamics in the generation of a mesoscale gravity wave event over the East Coast of the United States. Comparison of these tools in this case study shows that these various methods agree to a large extent with each other though they differ in details. Key words Unbalanced flow - Geostrophic adjustment - Gravity waves - Nonlinear balance equation - Potential vorticity inversion - Omega equations - Rossby number This research was conducted under support from NSF grant ATM-9700626 of the United States. The numerical computations described herein were performed on the Cray T90 at the North Carolina Supercomputing Center and the Cray supercomputer at the NCAR Scientific Computing Division, which also provided the initialization fields for the MM5. Thanks are extended to Mark Stoelinga at University of Washington for the RIP post-processing package.

关键词： Unbalanced flow Geostrophic adjustment Gravity waves Nonlinear balance equation Potential vorticity inversion Omega equations Rossby number

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The biodiversity of myxomycetes in central Chile

引用

Fungal Diversity 2013年第2期59卷 3-32页

作者： Carlos lado Diana Wrigley de Basanta Arturo Estrada-Torres steven l.Stephenson Real Jardín Botánico de Madrid CSIC.Plaza de Murillo228014 MadridSpain Centro de Investigación en Ciencias Biológicas Univ.Autónoma de TlaxcalaApdo.Postal 183Tlaxcala 90000Mexico Department of Biological Sciences University of ArkansasFayettevilleAR 72701USA

The results obtained from two expeditions to survey the biodiversity of myxomycetes in Central Chile are reported in this *** surveys were carried out as part of Global Biodiversity of Eumycetozoans project funded by the National Science Foundation(USA)and the Myxotropic project funded by the Spanish *** expeditions were made to the temperate zone of the central part of the country between 23°and 39°South latitudes,which is characterized by Mediterranean vegetation,as well as to the transition areas between the arid and semi-arid regions of northern Chile,and the humid,cold Valdivian and Andean-Patagonian forests of the far *** of the fifteen regions of the country,from Antofagasta to Araucanía,in selected areas where the native vegetation is well preserved,were included in these *** 600 collections were obtained,and a total of 110 species of myxomycetes representing 29 genera have been *** of these(Dianema succulenticola,Didymium chilense)are species new to science and are described in this paper,12 species(Collaria nigricapillitia,Comatricha alta,Cribraria oregana,Dianema depressum,Didymium eximium,***,Enerthenema melanospermum,lepidoderma chailletii,Macbrideola ovoidea,Physarum clavisporum,*** and Trichia alpina)were previously unknown for either the Neotropics or South America,and 49 additional species are new records for *** are provided on the morphology,distribution and ecology of selected species and light and SEM micrographs of the most significant species are *** evaluation of the biodiversity of myxomycetes in Chile,with special emphasis on the endemic plants that provided the substrates with which they were associated,and a comparative analysis of our results with those from other countries of South America is presented.

关键词： Amoebozoa Distribution Endemic plants Mediterranean vegetation Myxogastria Plasmodial slime moulds

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A refutation of reported levallois technology from Guanyindong Cave in south China

引用

National Science Review 2019年第6期6卷 1094-1096页

作者： Feng li Yinghua li Xing Gao steven l.Kuhn Eric Boёda John W.Olsen Key laboratory of Vertebrate Evolution and Human Origins of the Chinese Academy of Sciences Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences CAS Center for Excellence in life and Paleoenvironment School of History Wuhan University University of Chinese Academy of Sciences School of Anthropology University of Arizona C.N.R.S.-UMR7041 Anthropologie des techniques des espaces et des territoires au Plio-Pléistocène Maison Archéologie et Ethnologie

As one of the most complex forms of lithic technology known for the Paleolithic, research on the levallois stoneknapping method is critically relevant to our understanding of the cognitive abilities and depth of planning capabilities of archaic hominins, as well as the diffusion of knowledge and social learning in Pleistocene societies. For decades,

关键词： A refutation of reported levallois technology from Guanyindong Cave in south China

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：