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Isolated unilateral chorea:a diagnostic challenge

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Neuroimmunology and Neuroinflammation 2016年第1期3卷 260-261页

作者： Marta Lopes Eva Brandão Department of Neurology Hospital São SebastiãoEntre Douro e Vouga Hospital Centre4720-411 Santa Maria da FeiraPortugal

Movement disorders of paraneoplastic etiology are very rare,representing solely about 1%of all paraneoplastic neurological syndromes.^([1])The most frequently associated carcinoma is small-cell lung cancer,although several others are reported such as hematologic,bowel,breast,prostate and *** was reported an association with CV2/CRMP5,Anti-Hu/ANNA,CASPR2 and Yo antibodies,which are detectable in serum in most cases,isolated or in association.^([1-4])However,in a minority of cases an autoantibody cannot be detected.^([1])The antibody most frequently associated with paraneoplastic chorea is CV2/CRMP5,followed by Anti-Hu/ANNA.

关键词： bladder neoplastic lung

Emergence of neural regulatory mechanisms in carcinogenesis

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World Journal of Clinical oncology 2019年第8期10卷 279-282页

作者： Trisheena Harricharran olorunseun o ogunwobi Department of Biological Sciences Hunter College of the City University of New YorkNew YorkNY 10065United States The Graduate Center Departments of Biology and Biochemistry the City University of New YorkNew YorkNY 10016United States Joan and Sanford I Weill Department of Medicine Weill Cornell MedicineCornell UniversityNew YorkNY 10065United States Hunter College Center for Cancer Health Disparities Research New YorkNY 10065United States

Emerging data indicate that the nervous system plays an important role in carcinogenesis. However, more studies are required to help further elucidate the mechanisms involved in the neural regulation of carcinogenesis. Some recent findings describing the neural regulatory mechanisms of action in prostate cancer, pancreatic cancer and hepatocellular carcinoma are discussed, with a focus on the sympathetic, parasympathetic, and sensory neuronal elements of the nervous system. Norepinephrine, which is released by the sympathetic nervous system and binds to the beta-adrenergic receptor, regulates cellular responses in both normal and tumor cells. It has also been shown that the destruction of sensory neurons can prevent or at least slow pancreatic cancer. Cortisol, the main stress hormone, is also discussed and how it could potentially be involved in hepatocellular carcinoma development. The importance of studying other signaling molecules in the nervous system, such as oxytocin and its receptor, the oxytocin receptor, and how they might be involved in carcinogenesis when aberrantly expressed is highlighted. This is an area of study which clearly needs further investigation. A clearer understanding of the detailed mechanisms of how the nervous system is involved in carcinogenesis could potentially aid in the identification of novel biomarkers and development of novel preventative and therapeutic strategies in various cancers.

关键词： Neural regulation Prostate Pancreatic cancer Hepatocellular carcinoma oxytocin oxytocin receptor

Distribution and Association of Arbuscular Mycorrhizal Fungi in Different Cultivars of Wheat from Lalganj Pratapgarh District of Utter Pradesh, India

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Advances in Bioscience and Biotechnology 2015年第5期6卷 353-357页

作者： o. P. Dwivedi Lab of Mycology and Plant Pathology P.G. Department of Botany S.V.M. Science & Technology P. G. College Lalganj Pratapgarh 230132 Uttar Pradesh India

Arbuscular mycorrhizal fungi are key components of soil micro-flora and obviously interact with other microorganisms in the rhizosphere which is the zone of influence of plant roots on microbial populations and other soil constituents. Keeping in view the importance of AM fungi, the present study was undertaken for assessing the AM fungal spore population dynamics in the rhizosphere soil and its colonization in rhizosphere soils in relation to soil physico-chemical factors. Present study represents an attempt to establish the qualitative and quantitative distribution of AM fungal species in rhizosphere soils of wheat. Thirteen different wheat cultivars collected from four different sites of Lalganj Pratapgarh (U.P.), India were examined for the AM infection. All the wheat cultivars were found to be infected with arbuscular mycorrhizae. However, their population in rhizosphere and root infection varied to a considerable extent from species to species. The maximum spore population and highest percentage of root colonization were found with the rhizosphere soil of cultivars Ankur Kedar.

关键词： AM Fungi Root Colonization Wheat Cultivar

Arginase as a Potential Target in the Treatment of Alzheimer’s Disease

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Advances in Alzheimer's Disease 2018年第4期7卷 119-140页

作者： Baruh Polis Abraham o. Samson The Azrieli Faculty of Medicine Bar-Ilan University Safed Israel

Alzheimer’s disease (AD) is a slowly progressive, neurodegenerative disorder with an insidious onset that is characterized by severe decline in memory, thinking and reasoning skills. Advanced age is a prominent risk factor for AD and other metabolic diseases, such as type II diabetes and atherosclerosis. Their causal mechanisms are multifaceted and not fully understood. The precise pathophysiology of AD remains a mystery despite decades of intensive investigation. Thus far, there is no truly successful AD therapy. Arginase is the central enzyme of the urea cycle. Recent studies have identified arginase function in the brain and associated this enzyme with the development of neurodegenerative diseases. Upregulation of arginase has been shown to contribute to endothelial dysfunction, ischemia-reperfusion, atherosclerosis, diabetes, and neurodegeneration. other state-of-the-art discoveries of the precise molecular machinery of neurodegeneration have provided new directions for the rational development of innovative therapeutic strategies in the treatment of common neurodegenerative diseases. In this context, the regulation of arginase activity appears to be a universal approach in interfering with the pathogenesis of AD and providing relief for it and other metabolic disorders. Therefore, the enzyme represents a novel therapeutic target. Arginase inhibition has been shown to reverse amyloid-driven neuronal dysfunction and microgliosis and prevent the development of other AD symptoms in rodent models of AD. Consequently, the methodology represents a promising direction for clinical development.

关键词： Alzheimer’s Disease L-Norvaline L-Arginine Arginase

optimization of Thermal and Electrical Appliance Loads in Residential and Commercial Buildings with Demand Side Monitoring

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Smart Grid and Renewable Energy 2013年第7期4卷 16-26页

作者： Emmanuel o. B. ogedengbe Energhx Research Group Department of Mechanical Engineering Faculty of Engineering University of Lagos Lagos Nigeria.

Energy demand-supply mechanism with the load shape for both residential and commercial buildings in the Province of ontario and Nigeria is studied with demand side monitoring of energy consumption. Thermal and electrical loads are characterized by certain predictor variables, including the consumers’ behavioural pattern, power ratings of energy appliances and weather conditions. The proposed bottom-up approach is capable of providing low-volume electricity and natural gas consumers, in a fully deregulated energy market, with competitive energy saving advantage, based on corrective monitoring of independent users’ demand loads. Special application of the bottom-up model-based facility characterization of demands for thermal comfort and indoor air qualityin a developing energy sector like Nigeria enables the development of planning tool for the proposed integration of renewable power systems. The developed DSMonitorTM app is capable of deploying an effective smart grid technology tool towards an improved building energy demand-supply balance at the individual end-user level.

关键词： optimization Polynomial Regression Electricity Natural Gas Energy Stocks DSMonitorTM Smart Grid

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用于激光器的电感储能发生器(英文)

光学精密工程 2011年第2期19卷 213-220页

作者： TARASENKo V F PANCHENK o A N TEL’MINoV A E GENIN D E Institute of High Current Electronics SB RAS Akademichesky ave.2/3634055TomskRussia

研制了适用于激光器的电感储能发生器（GIES）,并研究了它在高压混合气体中的放电和激光参数。研究表明,电感储能发生器可产生高压预脉冲并引起放电电流的突然增大,可在不同的混合气体中形成长时间的稳定放电,从而方便地控制和优化每一... 详细信息

研制了适用于激光器的电感储能发生器（GIES）,并研究了它在高压混合气体中的放电和激光参数。研究表明,电感储能发生器可产生高压预脉冲并引起放电电流的突然增大,可在不同的混合气体中形成长时间的稳定放电,从而方便地控制和优化每一种气体混合物的预脉冲参数。在未知IES击穿电压和首次放电幅度下的参数时,电流尖峰会按因子1.52减少,从而产生纯激光参数。得到了氮气激光器的最大的辐射功率,输出能量和脉冲持续时间,在脉冲持续时间为40 ns时,紫外输出高达50 mJ,红外输出高于25 mJ,实现了氮分子激光跃迁的级联激射。因此C^3Пu-B^3Пg带总的脉冲持续时间延长至100 ns。在XeCl,XeF和KrF受激准分子激光器中,脉冲宽度和输出能量都得到了改善。XeF激光器的最大效率达到了1.6%,同时峰值输出能量达到了0.85 J,最大脉冲持续时间超过了200 ns。在248 nm波长处,效率3.3%的KrF激光器产生的160 ns脉冲能量高达650 mJ,最终得到了效率为7.7%10%的非链式HF（DF）激光器。演示了基于Co2分子高峰值功率的有效运行,结果表明,激光器在10 600 nm处的输出能量为6.2 J,转换效率高达25%。

关键词：电感储能发生器高压气体体放电激光参数

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Brucellosis in China:history,progress and challenge

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Infectious Diseases of Poverty 2020年第3期9卷 101-104页

作者： Hai Jiang David o’Callaghan Jia-Bo Ding State Key Laboratory for Infectious Disease Prevention and Control Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesNational Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina VBMI Universite de MontpellierINSERMUFR Medecine186Chemin du Carreau de Lanes30908 Nimes Cedex 2France Centre National de Reference Brucella CHU de NimesNimesFrance Department of Diagnostic Technology China Institute of Veterinary Drug ControlBeijingChina

Brucellosis is a neglected *** causes acute febrile illness and a potentially debilitating chronic infection in humans,and livestock infection has substantial socioeconomic *** the past two decades,improvements have been made to better understand the various aspects of human and animal ***,especially in the developing world,immense challenges that remain in controlling and eradicating brucellosis are novel diagnostics tools and efficacious ***,we will focus on the remarkable issues on epidemiological survey,as well as the priority and challenge of brucellosis in *** will be controlled with meaningful collaboration between local and public partnerships effectively applying a one Health framework.

关键词： Brucellosis Neglected zoonosis one health

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Global economic crisis and market trend in local timber in ogun state,nigeria:the climate change advantage

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林业经济评论 2015年第1期 25-31页

作者： J.A.Soaga olorunfemi,o. Department of Forestry&Wildlife management Federal University of Agriculture

The study examined the effect of global economic crisis（2005 ~ 2009） on forest conservation and carbon sink with contribution towards climate *** State was zoned into four strata based on ethnic and geographical *** strata are Egba,Yewa,Ijebu and *** data from ogun State Ministry of Forestry were subjected to statistical analysis to examine the demand trend of local timber in the *** result shows that there was low demand and weak market between 2005 and *** demand dropped from 58,468 in 2005 to 13,540 in 2009 representing 76.9% ***,sawmills decreased from 290 units in 2005 to 207 in 2009 representing 39.2% *** softwood and hardwood species were exploited The climate change advantage was identified through the amount of carbon sink estimated at 8,470 mg C for 1 loha of natural species based on previous *** translates into reduced forest degradation and deforestation（REDD） and the resiliency of the forest allowed for *** is recommended that forest policy must encourage reduced exploitation through ecocentrism ideology to allow immature species to grow and improve carbon sequestration through forest resiliency and consequently protect the environment from greenhouse gas emission.

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Efficacy of Plant Based Insecticides in Control of Leaf Defoliators(Podagrica uniformis Jacoby and Nisotra sjostedti Jacoby(Coleoptera: Chrysomelidae) of okra(Abelmoschus esculentus L. Moench)

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Journal of Northeast Agricultural University(English Edition) 2016年第4期23卷 1-7页

作者： odewole A F Adebayo T A Dada A o Department of Crop and Environmental Protection Ladoke Akintola University of Technology

The insecticidal efficacy of aqueous extracts of R. communis L. and Z. officinales L. was tested in a field study for the control of two important leaf defoliators （Podagrica uniformis and Nisotra sjostedti of okra）. The extracts were applied at 10% （w/v） and sprayed every week for five consecutive weeks. R. communis significantly reduced （P〈0.05） abundance of the pests on the 2nd day after spraying and increased the yield of okra. Numbers of fruits and weight yields were significantly higher in plots treated with R. communis compared to plots treated with Z. officinales and the untreated control. R. communis had the same weight yield with Karate （synthetic insecticides）. The results indicated that R. communis could be used to control Podagrica uniformis and Nisotra sjostedti of okra.

关键词： extracts okra Podagrica uniform Nisotra sjostedti R. communis Z. officinales

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