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Key technologies for wireless network digital twin towards smart railways

High-Speed Railway 2024年第1期2卷 1-10页

作者： Ke Guan Xinghai Guo Danping He Philipp Svoboda Marion Berbineau stephen wang Bo Ai Zhangdui Zhong Markus Rupp State Key Laboratory of Advanced Rail Autonomous Operation Beijing Jiaotong UniversityBeijing 100044China School of Electronic and Information Engineering Beijing Jiaotong UniversityBeijing 100044China Christian Doppler Laboratory for Digital Twin Assisted AI for Sustainable Radio Access Networks Institute of TelecommunicationsTU WienVienna 1040Austria UniversitéGustave Eiffel COSYSLEOSTVilleneuve d′Ascq 59650France VIAVI Marconi Labs VIAVI SolutionsStevenage SG12ANUK Institute of Telecommunications TU WienVienna 1040Austria

An emerging railway technology called smart railway promises to deliver higher transportation efficiency,enhanced comfort in services,and greater *** smart railway is expected to integrate fifth-generation mobile communication(5G),Artificial Intelligence(AI),and other technologies,which poses new problems in the construction,operation and maintenance of railway wireless *** Digital Twins(DTs),which have recently emerged as a new paradigm for the design of wireless networks,can address these problems and enable the whole lifecycle management of railway wireless ***,there are still many scientific issues and challenges for railway-oriented wireless *** key technologies to solve these problems are introduced and described,including characterization of materials'physical-EM properties,autonomous reconstruction of Three-dimensional(3D)environment model,AI-empowered environmental cognition,Ray-Tracing(RT),model-based and AIbased RT acceleration,and generation of multi-spectra sensing ***,this paper presents our research results for each key technology and describes the wireless network planning and optimization system based on highperformance RT developed by our *** paper outlines the framework for realizing the wireless DT of smart railways,providing the direction for future research.

关键词： Digital twin Smart railways Ray tracing Channel characterization

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Effect of austenitizing condition on mechanical properties,microstructure and precipitation behavior of AISI H13 steel

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Journal of Iron and Steel Research(International) 2024年第1期31卷 143-156页

作者： An-gang Ning Yang Liu Rui Gao stephen Yue Ming-bo wang Han-jie Guo College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan030024ShanxiChina Department of Mining and Materials Engineering McGill UniversityMontrealQCH3A 0C5Canada ASSAB Tooling Technology(Chongqing)Co. Ltd.Chongqing401120China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China

The effects of austenitizing temperature(1223,1303,and 1373 K)and holding time(1-1500 s)on the microstructure,mechanical properties,and precipitation behavior of the H13 hot work die steel were *** results indicate a softening phenomenon when H13 steel is austenitized at 1303 K beyond 900 s and 1373 K beyond 600 s,*** the sample held for 1200 s,the tensile strength is found capable of reaching up to 2.2 GPa when quenched from a temperature above 1303 ***,prior-austenite grain size increases with the increase in austenitizing *** kinetic behavior of the precipitates(mainly MC-type carbides)in H13 steel could be elaborated through the principles set forth by the Arrhenius and Avrami ***,the comprehensive strengthening of the H13 steel was discussed in *** results show that the activation energy of the transformed fraction of carbides is higher than that of the diffusion process for common alloying elements(Cr,V,Mo,and Ni)found in the *** suggests that it would be difficult for precipitates to dissolve into the matrix when H13 steel is austenitized at high *** the increasing austenitizing temperature,the precipitation fraction decreases,and the dislocation density *** dislocation strengthening is regarded as the dominant strengthening contributed to yield strength in as-quenched H13 steel.

关键词： H13 steel Austenitizing Mechanical property Precipitation behavior Comprehensive strengthening

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Detecting subtle yet fast skeletal muscle contractions with ultrasoft and durable graphene-based cellular materials

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National Science Review 2022年第4期9卷 105-115页

作者： Zijun He Zheng Qi Huichao Liu Kangyan wang Leslie Roberts Jefferson Z.Liu Yilun Liu stephen J.wang Mark J.Cook George P.Simon Ling Qiu Dan Li Shenzhen Geim Graphene Center Tsinghua-Berkeley Shenzhen InstituteTsinghua University Department of Chemical Engineering The University of Melbourne Department of Materials Science and Engineering Monash University Department of Chemical Engineering Monash University State Key Laboratory for Strength and Vibration of Mechanical Structures School of Aerospace EngineeringXi'an Jiaotong University Neurophysiology Department Department of Neurology and Neurological ResearchSt Vincent's Hospital Department of Medicine St.Vincent's HospitalUniversity of Melbourne Department of Mechanical Engineering University of Melbourne Department of Design Monash University School of Design The Hong Kong Polytechnic University

Human bodily movements are primarily controlled by the contractions of skeletal muscles. Unlike joint or skeletal movements that are generally performed in the large displacement range, the contractions of the skeletal muscles that underpin these movements are subtle in intensity yet high in frequency. This subtlety of movement makes it a formidable challenge to develop wearable and durable so?t materials to electrically monitor such motions with high fidelity for the purpose of, for example, muscle/neuromuscular disease diagnosis. Here we report that an intrinsically fragile ultralow-density graphene-based cellular monolith sandwiched between silicone rubbers can exhibit a highly effective stress and strain transfer mechanism at its interface with the rubber, with a remarkable improvement in stretchability(>100%). In particular, this hybrid also exhibits a highly sensitive, broadband-frequency electrical response(up to 180 Hz) for a wide range of strains. By correlating the mechanical signal of muscle movements obtained from this hybrid material with electromyography, we demonstrate that the strain sensor based on this hybrid material may provide a new, so?t and wearable mechanomyography approach for real-time monitoring of complex neuromuscular–skeletal interactions in a broad range of healthcare and human–machine interface applications. This work also provides a new architecture-enabled functional so?t material platform for wearable electronics.

关键词： cellular graphene strain sensors high-frequency electromechanical property surface mechanomyography skeletal muscle activity

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DCFNet:Discriminant Correlation Filters Network for Visual Tracking

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Journal of Computer Science & Technology 2024年第3期39卷 691-714页

作者：胡卫明王强高晋李兵 stephen Maybank State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of AutomationChinese Academy of Sciences Beijing 100190China Department of Computer Science and Information Systems Birkbeck CollegeLondon WC1E 7HXU.K.

CNN(convolutional neural network)based real time trackers usually do not carry out online network update in order to maintain rapid tracking *** inevitably influences the adaptability to changes in object *** filter based trackers can update the model parameters online in real *** this paper,we present an end-to-end lightweight network architecture,namely Discriminant Correlation Filter Network(DCFNet).A differentiable DCF(discriminant correlation filter)layer is incorporated into a Siamese network architecture in order to learn the convolutional features and the correlation filter *** correlation filter can be efficiently updated *** previous work,we introduced a joint scale-position space to the DCFNet,forming a scale DCFNet which carries out the predictions of object scale and position *** combine the scale DCFNet with the convolutional-deconvolutional network,learning both the high-level embedding space representations and the low-level fine-grained representations for *** adaptability of the fine-grained correlation analysis and the generalization capability of the semantic embedding are complementary for visual *** back-propagation is derived in the Fourier frequency domain throughout the entire work,preserving the efficiency of the *** evaluations on the OTB(Object Tracking Benchmark)and VOT(Visual Object Tracking Challenge)datasets demonstrate that the proposed trackers have fast speeds,while maintaining tracking accuracy.

关键词： correlation filter convolutional neural network(CNN) visual tracking

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Potentials of ribosomopathy gene as pharmaceutical targets for cancer treatment

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Journal of Pharmaceutical Analysis 2024年第3期14卷 308-320页

作者： Mengxin wang stephen Vulcano Changlu Xu Renjian Xie Weijie Peng Jie wang Qiaojun Liu Lee Jia Zhi Li Yumei Li Key Laboratory of Biomaterials and Biofabrication in Tissue Engineering of Jiangxi Province Gannan Medical UniversityGanzhouJiangxi341000China School of Rehabilitation Medicine Gannan Medical UniversityGanzhouJiangxi341000China Autoimmunity and Inflammation Program HSS Research InstituteHospital for Special Surgery New YorkNew YorkNY10021USA Division of Oral and Systemic Health Sciences School of DentistryUniversity of CaliforniaLos AngelesCA90095USA School of Medical Information Engineering Gannan Medical UniversityGanzhouJiangxi341000China Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Anhui Institute of Innovative DrugsInstitute for Liver Diseases of Anhui Medical UniversitySchool of PharmacyAnhui Medical UniversityHefei230032China School of Basic Medicine Gannan Medical UniversityGanzhouJiangxi341000China Institute of Oceanography Minjiang UniversityFuzhou350108China

Ribosomopathies encompass a spectrum of disorders arising from impaired ribosome biogenesis and reduced *** or dysexpression of the genes that disturb any finely regulated steps of ribosome biogenesis can result in different types of ribosomopathies in clinic,collectively known as ribosomopathy *** data suggest that ribosomopathy patients exhibit a significantly heightened susceptibility to *** ribosome biogenesis and dysregulation of some ribosomopathy genes have also been found to be intimately associated with cancer *** correlation between ribosome biogenesis or ribosomopathy and the development of malignancies has been well *** work aims to review the recent advances in the research of ribosomopathy genes among human cancers and meanwhile,to excavate the potential role of these genes,which have not or rarely been reported in cancer,in the disease development across *** plan to establish a theoretical framework between the ribosomopathy gene and cancer development,to further facilitate the potential of these genes as diagnostic biomarker as well as pharmaceutical targets for cancer treatment.

关键词： Ribosome biogenesis Ribosomopathy gene Cancer treatment target Pharmaceutical target

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Circumscription of the East Asia clade (Apiaceae subfamily Apioideae) and the taxonomic placements of several problematic genera

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Plant Diversity 2024年第2期46卷 206-218页

作者： Jing Zhou Xinyue wang Shilin Zhou Junmei Niu Jiarui Yue Zhenwen Liu stephen R.Downie School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products Kunming Medical University1168 Western Chunrong RoadYuhua StreetChenggong New CityKunming 650500China Yunnan Academy of Forestry and Grassland Kunming 650201China Gaoligong Mountain Forest EcosystemObservation and Research Station of Yunnan ProvinceKunming 650201China Yunnan Key Laboratory of Biodiversity of Gaoligong Mountain Kunming 650201China Department of Plant Biology University of Illinois at Urbana-ChampaignUrbanaIL 61801USA College of Modern Biomedical Industry Kunming Medical UniversityKunming 650500China

The East Asia(or Physospermopsis) clade was recognized in previous molecular phylogenetic investigations into the higher-level relationships of Apiaceae subfamily Apioideae. The composition of this clade, the phylogenetic relationships among its constituent taxa, and the placement of species previously determined to be problematic have yet to be resolved. Herein, nr DNA ITS sequences were obtained for150 accessions of Apioideae, representing species whose distributions are in East Asia or genera having one or more species included within the East Asia clade. These data, along with published ITS sequences from other Apioideae(for 3678 accessions altogether), were subjected to maximum likelihood and Bayesian inference analyses. The results show that the East Asia clade contains representatives of 11currently recognized genera: Hansenia, Hymenolaena, Keraymonia, Sinolimprichtia, Acronema, Hymenidium, Physospermopsis, Pimpinella, Sinocarum, Tongoloa, and Trachydium. However, the latter seven genera have members falling outside of the East Asia clade, including the generic types of all except Tongoloa. Within the clade, the species comprising these seven genera are widely intermingled, greatly increasing confusion among relationships than previously realized. The problematic species Physospermopsis cuneata is confirmed as falling within the East Asia clade, whereas P. rubrinervis allies with the generic type in tribe Pleurospermeae. Physospermopsis kingdon-wardii is confirmed as a member of the genus Physospermopsis, whereas the generic attributions of P. cuneata and Tongoloa stewardii remain unclear. Two species of Sinocarum(S. filicinum and S. wolffianum) are transferred into the genus Meeboldia. This is the most comprehensive molecular phylogenetic investigation of the East Asia clade to date, and while the results increase systematic understanding of the clade, they also highlight the need for further studies of one of the most taxonomically intractable groups in Api

关键词： Physospermopsis Pimpinella Sinocarum Tongoloa Trachydium

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Mitochondria-targeted atovaquone promotes anti-lung cancer immunity by reshaping tumor microenvironment and enhancing energy metabolism of anti-tumor immune cells

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Cancer Communications 2024年第3期44卷 448-452页

作者： Donghai Xiong Zheng Yin Mofei Huang Yian wang Micael Hardy Balaraman Kalyanaraman stephen T Wong Ming You Center for Cancer Prevention Houston Methodist Neal Cancer CenterHouston Methodist HospitalWeill Cornell MedicineHoustonTexasUSA Department of Systems Medicine and Bioengineering Houston Methodist Cancer CenterHouston Methodist HospitalWeill Cornell MedicineHoustonTexasUSA Aix Marseille Univ Centre Nationaldela Recherche Scientifique(CNRS)Institut de Chimie Radicalaire(ICR)UnitéMixte de Recherche(UMR)7273MarseilleFrance Department of Biophysics Medical College of WisconsinMilwaukeeWisconsinUSA

Dear Editor,Atovaquone(ATO),a mitochondrial inhibitor,has anti-cancer effects[1].Based on ATO,we developed mitochondria-targeted atovaquone(Mito-ATO)that had even stronger anti-tumor efficacy than ATO[2].We syn-thesized Mito-ATO by attaching the bulky triphenylphos-phonium(TPP)group to ATO via a ten-carbon alkyl chain(Supplementary file of methods;Supplementary Figure S1).

关键词： metabolism immunity targeted

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The reformation of catalyst:From a trial-and-error synthesis to rational design

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Nano Research 2024年第4期17卷 3261-3301页

作者： Ligang wang Jiabin Wu Shunwu wang Huan Liu Yao wang Dingsheng wang Department of Chemistry Tsinghua UniversityBeijing 100084China

The appropriate catalysts can accelerate the reaction rate and effectively boost the efficient conversion of various molecules,which is of great importance in the study of chemistry,chemical industry,energy,materials and environmental ***,efficient,environmentally friendly,and easy to operate synthesis methods have been used to prepare various types of *** previous studies have reported the synthesis and characterization of the aforementioned catalysts,more still remain in trial and error methods,without in-depth consideration and improvement of traditional synthesis ***,we comprehensively summarize and compare the preparation methods of the trial-and-error synthesis strategy,structure–activity relationships and density functional theory(DFT)guided catalysts rational design for nanomaterials and atomically dispersed *** also discuss in detail the utilization of the nanomaterials and single atom catalysts for converting small molecules(H_(2)O,O_(2),CO_(2),N_(2),etc.)into value-added products driven by electrocatalysis,photocatalysis,and ***,the challenges and outlooks of mass preparation and production of efficient and green catalysts through conventional trial and error synthesis and DFT theory are featured in accordance with its current development.

关键词： trial-and-error synthesis structure–activity relationships density functional theory(DFT)guidance nanomaterials atomically dispersed catalysts

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Numerical Analysis of PRISM-PY Calculations for Hard-and Soft-Core Generic Polymer Models

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Chinese Journal of Polymer Science 2024年第4期42卷 532-543页

作者： Qiang wang Department of Chemical and Biological Engineering Colorado State University1370 Campus DeliveryFort CollinsCO80523-1370USA

Generic polymer models capturing the chain connectivity and excluded-volume interactions between polymer segments can be classified, according to whether or not the 3D integral of the latter diverges, into hard- and soft-core models. Taking homogeneous systems of compressible homopolymer melts (or equivalently homopolymer solutions in an implicit, good solvent) in the continuum as an example, we recently compared the correlation effects on the structural and thermodynamic properties of the hard- and soft-core models given by the polymer reference interaction site model (PRISM) theory with the Percus-Yevick (PY) closure (Polymers 2023, 15, 1180). Here we analyzed in detail the numerical errors and behavior of the interchain pair correlation functions (PCFs) given by the PRISM-PY calculations of these models using an efficient numerical approach that we proposed. Our numerical approach has the least number of independent variables to be iteratively solved, analytically treats the discontinuities caused by the non-bonded pair potential (such as that of the hard spheres) and takes only the inverse Fourier transform of the interchain indirect PCF between polymer segments (which is continuous and decays towards 0 with increasing wavenumber much faster than both the interchain direct and total PCFs), and is essential for us to accurately solve the PRISM-PY theory for chain length N as large as 106. To capture the correlation-hole effect, the real-space cut-off in the PRISM calculations should be proportional to the square root of N.

关键词： Generic polymer models Soft potentials Polymer reference interaction site model theory

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Linear-Quadratic Pareto Cooperative Game for Mean-Field Backward Stochastic System

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Journal of Systems Science & Complexity 2024年第3期37卷 947-964页

作者： wang Yu School of Control Science and Engineering Shandong UniversityJinan 250061China

This paper focuses on a Pareto cooperative differential game with a linear mean-field backward stochastic system and a quadratic form cost functional. Based on a weighted sum optimality method, the Pareto game is equivalently converted to an optimal control problem. In the first place,the feedback form of Pareto optimal strategy is derived by virtue of decoupling technology, which is represented by four Riccati equations, a mean-field forward stochastic differential equation(MF-FSDE),and a mean-field backward stochastic differential equation(MF-BSDE). In addition, the corresponding Pareto optimal solution is further obtained. Finally, the author solves a problem in mathematical finance to illustrate the application of the theoretical results.

关键词： Backward stochastic differential equation linear-quadratic control mean-field Pareto optimality

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