检索结果-南通市图书馆

物探化探译丛 1997年第A2期 74-78页

作者： harris,e 刘心铸

Beam energy measurement system at BePCⅡ

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics C 2010年第6期34卷 912-917页

作者：莫晓虎 e.V.Abakumova M.N.Achasov V.e.Blinov 初元萍董海义傅成栋 F.A.harris V.V.Kaminskiy A.A.Krasnov 李小南刘倩 N.Yu.Muchnoi I.B.Nikolaev e.e.Pyata 屈化民秦庆 A.G.Shamov 沈成平 G.S.Varner 王贻芳徐金强张建勇张清江张银鸿张天保 V.N.Zhilich 赵卓 A.A.Zhukov Institute of High energy Physics Chinese Academy of Sciences Budker Institute of Nuclear Physics University of Hawaii

The beam energy measurement system at BePCII is composed of there parts： laser source and optics system, laser-electron interaction system and High Purity Germanium （HPGe） detector system. The special components and construction of each part are introduced, especially about radiation background measurement in the storage ring, which is of great importance for the safe commissioning of HPGe detector.

关键词： energy measurement laser electron HPCe detector

维普期刊数据库

自身免疫性血小板减少性紫瘢病人的抗心脂抗体

在线全文

学校读者我要写书评

暂无评论

潍坊医学院学报 1985年第2期10卷 144-145,151页

作者： e N harris 岳启安

近来应用设计的一种固相放射免疫试验检测抗心脂抗体,我们报告了在96例慢性自身免疫性血小板减少性紫瘢(AITP)病人有30例存在抗心脂抗体,14例病人有升高的 IgG 抗心脂抗体水平,27例有升高的 IgM 抗心脂抗体水平。我们指出这些抗体通过... 详细信息

近来应用设计的一种固相放射免疫试验检测抗心脂抗体,我们报告了在96例慢性自身免疫性血小板减少性紫瘢(AITP)病人有30例存在抗心脂抗体,14例病人有升高的 IgG 抗心脂抗体水平,27例有升高的 IgM 抗心脂抗体水平。我们指出这些抗体通过与血小板膜上的磷脂结合介导周围血中的血小板的破坏,也可以推想,由于这些抗心脂抗体的存在,可以选出能继续发展成其它自身免疫性疾病,例如,系统性红斑性狼疮的慢性 AITP 的病人亚群。

关键词：抗心脂抗体 AITP 血小板减少性病人紫瘢紫癜自身免疫性

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

烷基9-氮硝基喜树碱酯类的构效关系

Acta Pharmacologica Sinica 2003年第2期24卷 109-119页

作者： Panayotis PANTAZIS John MeNDOZA Janet eARLY Anthony KOZIeLSKI Nick harris Beppino GIOVANeLLA The Stehlin Foundation for Cancer Research at St. Joseph Hospital 1918 Chenevert Houston Texas 77003 USA The Stehlin Foundation for Cancer Research at St. Joseph Hospital 1918 Chenevert Houston Texas 77003 USA The Stehlin Foundation for Cancer Research at St. Joseph Hospital 1918 Chenevert Houston Texas 77003 USA The Stehlin Foundation for Cancer Research at St. Joseph Hospital 1918 Chenevert Houston Texas 77003 USA The Stehlin Foundation for Cancer Research at St. Joseph Hospital 1918 Chenevert Houston Texas 77003 USA The Stehlin Foundation for Cancer Research at St. Joseph Hospital 1918 Chenevert Houston Texas 77003 USA

AIM: To study the structure-activity relationship of alkyl 9-nitrocamptothecin esters. MeTHODS: Two alkyl 9-nitrocamptothecin (9NC) esters 5g and 5h were prepared by esterification reactions of 9NC with valeric anhydride and heptanoic anhydride, respectively. eight 9NC esters 5a-5h were tested for cytotoxicity against human leukemia cell lines HL-60 and U-937. Flow cytometry analysis was used to identify the cell cycle phase targeted by the esters and quantify the extent of ester-induced cell death (apoptosis). ReSULTS: esters 5b and 5c demonstrated great abilities to inhibit growth of the leukemia cells followed by induction of apoptosis; esters 5a, 5e, and 5g induced slight perturbations in the cell cycle at high concentrations; and esters 5d, 5f, and 5h were completely inactive against the cell lines tested. Thus these esters showed the cell anti-proliferative activity in an order of 5b≈5c>5a≈5e≈5g>5d≈5f≈5h. esters 5b, 5c, and 5e were tested in vivo against various human carcinomas in nude mice grown as xenografts. Only 5b and 5c showed a significant antitumor activity. Particularly, ester 5b demonstrated an antitumor activity against a broad spectrum of human carcinomas including breast, lung, colon, pancreas, stomach, ovarian, and melanoma, etc. CONCLUSION: These esters act like prodrugs of their parental 9-nitrocamptothecin. High drug doses need to be administered to animals in order to inhibit growth, and induce regression, of human tumor xenografts in nude mice. These compounds may be developed into potent anticancer drugs due to their low toxicity.

关键词：喜树碱酯类药物前体抗肿瘤药毒性构效关系

A scenario for high accuracy τ mass measurement at BePC-Ⅱ

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics C 2012年第7期36卷 573-577页

作者： M. N. Achasov V. e. Blinov 蔡啸傅成栋 F. A. harris Q. Liu 莫晓虎 N. Yu. Muchnoi I. B. Nikolaev 秦庆 A. G. Shamov K. Yu. Todyshev 王贻芳张建勇 Budker Institute of Nuclear Physics Siberian Branch of the Russian Academy of Sciences11 Lavrentyev Novosibirsk 630090 Russia Institute of High energy Physics Chinese Academy of Sciences University of Hawaii HonoluluHI 96822 USA

Scenarios for the τ mass measurement at the upgraded Beijing electron-Positron Collider （BePC- II ） are studied. A nested minimization procedure is used to optimize the data taking plan. It is found that by using five energy points with the total integrated luminosity of 100 pb-1, the τ mass can be determined with a statistical error of 50 keV.

关键词： τ mass scan optimization uncertainty

维普期刊数据库

在线全文

学校读者我要写书评

暂无评论

天然橡胶在生物技术上的新用途

橡胶参考资料 2000年第3期30卷 40-44页

作者： e.M.harris 高静茹

天然橡胶(NR)主要用于汽车轮胎上,大约有65%的马来西亚天然橡胶是被用在轮胎上的。剩余的35%中,20%用于浓缩胶乳产品,如垫子,手套、避孕套、玩具及医药产品。通用产品,如传输带、管及鞋类则消耗了剩余的15%。天然胶的应用绝大多数是利... 详细信息

天然橡胶(NR)主要用于汽车轮胎上,大约有65%的马来西亚天然橡胶是被用在轮胎上的。剩余的35%中,20%用于浓缩胶乳产品,如垫子,手套、避孕套、玩具及医药产品。通用产品,如传输带、管及鞋类则消耗了剩余的15%。天然胶的应用绝大多数是利用其独特的高弹性,以及天然胶的固体模压成型能力或是它可通过胶乳制成薄膜的能力。

关键词：天然橡胶生物技术汽车轮胎

现代理论物理导论第2卷量子理论与统计物理学 1

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

现代理论物理导论第2卷量子理论与统计物理学

Antioxidant and Anti-Inflammatory effects of Peanut Skin extracts

1985年

作者：（美）哈里斯（harris e.）何建鄂译

书名原文: Introduction to modern theretical physics .

ISBN: (纸本)13119·1238

书名原文: Introduction to modern theretical physics .

关键词：量子力学统计物理学

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

Food and Nutrition Sciences 2013年第8期4卷 22-32页

作者： Wanida e. Lewis Gabriel K. harris Timothy H. Sanders Brittany L. White Lisa L. Dean Department of Food Bioprocessing and Nutrition Sciences North Carolina State University Raleigh USA Market Quality and Handling Research Unit Agricultural Research Service United States Department of Agriculture Raleigh USA Market Quality and Handling Research Unit Agricultural Research Service United States Department of Agriculture Raleigh USA.

Peanut skins are regarded as a low economic value by-product of the peanut industry;however, they contain high levels of bioactive compounds including catechins and procyanidins, which are known for their health-promoting properties. The in vitro antioxidant activity of peanut skin extracts (PSe) has been reported but the associated anti-inflammatory properties have not been widely examined. This study investigated the anti-inflammatory effects of PSe on the pro-inflammatory enzyme, Cyclooxygenase-2 (COX-2) protein expression, on its downstream product, prostaglandin e2 (PGe2), and on nitrous oxide (NO) levels. Defatted peanut skins were extracted using two aqueous solvent mixtures (50% acetone and 90% ethanol), in order to compare the effects of the two solvent systems on antioxidant and anti-inflammatory properties. PSe antioxidant activity was determined by the hydrophilic oxygen radical absorbance capacity (H-ORAC) assay, while total phenolics were determined by the Folin-Ciocalteu assay and flavan-3-ols and procyanidins were quantified by HPLC. Acetone extracted PSe (A-PSe) exhibited numerically, but not statistically higher H-ORAC and total phenolic values than the ethanol extracted PSe (e-PSe) (1836 μmol Trolox/100 g and 67.9 mg GAe/g, and 1830 μmol Trolox/100 g and 51.8 GAe/g respectively). A-PSe also had higher levels of flavan-3-ols and procyanidins than e-PSe. RAW 264.7 cells were pretreated with 1.0%, 2.5% and 5.0% (v/v) of A-PSe or e-PSe and induced with the inflammatory marker, lipopolysaccharide (LPS) for 12 hours. COX-2 protein expression, measured by Western blotting was significantly (p 2 and NO levels measured by eLISA, were significantly (p ecreased with increasing added levels of A-PSe and e-PSe suggesting that A-PSe and e-PSe not also possess similar antioxidant properties, but also exhibit similar anti-inflammatory effects.

关键词： Peanut Skins Antioxidants Anti-Inflammatory Cyclooxygenase (COX-2) Prostaglandin e2 (PGe2) Nitric Oxide (NO) Procyanidins

Management, Triage and Outcomes of 378 Patients Presenting to the emergency Department with Chest Pain of Acute Onset： A Single Centre Observational Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Health Science 2014年第11期2卷 523-528页

作者： Samira Green Vanessa Jessop Jason Pott Tim harris University Hospitals Leicester Leicester LE1 5WW UK Royal London Hospital London e1 1BB UK

Chest pain accounts for 700,000 hospital attendances in the UK each year. Prompt risk assessment and diagnosis both improves outcomes and reduces unnecessary admissions. Data on patients who presented to the eD with chest pain was collected retrospectively. Patients were then followed up via hospital records and telephone. 70% of the authors＇ patients were triaged as low risk chest pain. Three represented within 30 d with non ischaemic chest pain. 1 patient had MACe. The authors＇ triage pathway safely managed those presenting with chest pain.

关键词： Acute coronary syndrome triage near patient testing troponin I risk stratification.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

超导电子学的空间应用之四数字电子学

低温与超导 1981年第3期 32-45页

作者： R.e.harris 罗美富许义民美国NBS电磁技术部科学家

超导电子学具有诸如高速、低功率耗散等优越性能,这无论是在地面或空间应用的高速计算和测量中,都是很有吸引力的。

关键词：超导电子学数字电子学约瑟夫逊结响应时间器件超导计算机空间应用