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Evidence for a female-produced, long range pheromone of Anoplophora glabripennis （Coleoptera Cerambycidae）

Insect Science 2012年第3期19卷 355-371页

作者： Jacob D.Wickham Zhichun Xu stephen a.teale Department of Environmental and Forest Biology SUNY College of Environmental Science and Forestry1 Forestry DriveSyracuseN Y 13210USA College of Forest Resources Beijing Forestry University Key Lab of Analytical Chemistry for Living Biosystems Institute of ChemistryChinese Academy of SciencesBeijingChina

Volatiles from female Asian longhorned beetle （ ALB ）, Anoplophora glabripenhis, were evaluated as candidate sex pheromone components. Previous studies on ALB have revealed several antennally active compounds from virgin females; however the origins and activity of these compounds were not apparent and require further investigation. We tested the hypothesis that one or more of the ALB contact sex pheromones is a precursor that undergoes abiotic oxidation to yield volatile pheromone components, and evaluated the activity of these compounds using laboratory and field bioassays. Gas chromatogra- phy coupled electroantennography detection （GC-EAD） analysis indicated the presence of three antennally active aldehydes （heptanal, nonanal, and hexadecanal） in female cuticular extracts exposed to ozone or UV and visible light. In laboratory bioassays using a Y-tube olfactometer, males were preferentially attracted to ozonized female body washes over crude body washes. Similarly, synthetic formulations of these compounds were preferred over controls in the olfactometer. Field trapping experiments conducted from 2006 to 2008 in Ningxia, China showed that synthetic lures of the three aldehydes formulated in a ratio simulating that of virgin females attracted more beetles compared to controls, and that combinations of these aldehydes, linalool oxide, and host kairomones captured more beetles than controls, and captured significantly more males.

关键词： Anoplophora glabripennis Asian longhorned beetle cuticular hydrocarbons,kairomone oxidation pheromone

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Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions

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Neural Regeneration Research 2025年第7期20卷 1991-1992页

作者： Fengwen Huang stephen Temitayo Bello Department of Neuroscience City University of Hong KongKowloon TongHong Kong Special Administrative RegionChina Center for Regenerative Medicine and Health Hong Kong Institute of Science&InnovationChinese Academy of SciencesHong Kong Special Administrative RegionChina

Spatial memory is crucial for survival within external surroundings and wild *** hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodulators shape its functions(Teixeira et al.,2018;Zhang et al.,2024).However,the landscape of neuromodulations in the hippocampal system remains poorly understood because most studies focus on classical monoamine neuromodulators,such as acetylcholine,serotonin,dopamine,and *** neuropeptides,comprising the most abundant neuromodulators in the central nervous system,play a pivotal role in neural information processing in the hippocampal ***(CCK),one of the most abundant neuropeptides,has been implicated in regulating various physiological and neurobiological statuses(Chen et al.,2019).CCK-A receptor(CCK-AR)and CCK-B receptors(CCK-BR)are two key receptors mediating the biological functions of CCK,both of which belong to class-A sevenfold transmembrane G protein-coupled receptors(Nishimura et al.,2015).CCK-AR preferentially reacts to sulfated CCK,whereas CCK-BR binds both CCK and gastrin with similar affinities(Ding et al.,2022).The expression patterns of CCK-AR and CCK-BR are distinct,implying that CCK has various functions in target *** instance,CCK-AR is widely expressed in the GI and brain subregions and is hence implicated in the control of digestive function and satiety ***,CCK-BR is abundantly and widely distributed in the central nervous system,which majorly regulates anxiety,learning,and memory(Ding et al.,2022).However,the roles of endogenous CCK and CCK receptors in regulating hippocampal function at electrophysiological and behavioral levels have received less attention.

关键词： abundant functions modulator

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Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury

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Neural Regeneration Research 2025年第11期20卷 3063-3075页

作者： stephen Vidman Yee Hang Ethan Ma Nolan Fullenkamp Giles W.Plant Department of Neuroscience Ohio State UniversityColumbusOHUSA

In recent years,the progression of stem cell therapies has shown great promise in advancing the nascent field of regenerative *** the non-regenerative nature of the mature central nervous system,the concept that“blank”cells could be reprogrammed and functionally integrated into host neural networks remained *** work has also demonstrated the ability of such cells to stimulate intrinsic growth programs in post-mitotic cells,such as *** embryonic stem cells demonstrated great potential in treating central nervous system pathologies,ethical and technical concerns *** barriers,along with the clear necessity for this type of treatment,ultimately prompted the advent of induced pluripotent stem *** advantage of pluripotent cells in central nervous system regeneration is multifaceted,permitting differentiation into neural stem cells,neural progenitor cells,glia,and various neuronal *** precise spatiotemporal application of extrinsic growth factors in vitro,in addition to microenvironmental signaling in vivo,influences the efficiency of this directed *** the pluri-or multipotency of these cells is appealing,it also poses the risk of unregulated differentiation and teratoma *** of the neuroectodermal lineage,such as neuronal subpopulations and glia,have been explored with varying degrees of *** the risk of cancer or teratoma formation is greatly reduced,each subpopulation varies in effectiveness and is influenced by a myriad of factors,such as the timing of the transplant,pathology type,and the ratio of accompanying progenitor ***,successful transplantation requires innovative approaches to develop delivery vectors that can mitigate cell death and support ***,host immune responses to allogeneic grafts must be thoroughly characterized and further developed to reduce the need for *** to a clinical setting wi

关键词： axon regeneration central nervous system regeneration induced pluripotent stem cells neurotrauma regenerative medicine spinal cord injury stem cell therapy

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Comprehensive Transcriptome Analysis of Auxin Responses in Arabidopsis

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Molecular Plant 2008年第2期1卷 321-337页

作者： Ivan A. Paponov Martina Paponovt William teale Margit Menges Sohini Chakrabortee James A.H. Murray Klaus Palme Faculty of Biology University of Freiburg Schanzlestrasse 1 79104 Freiburg Germany Institute of Biotechnology University of Cambridge Cambridge CB2 1QT United Kingdom

In plants, the hormone auxin shapes gene expression to regulate growth and development. Despite the detailed characterization of auxin-inducible genes, a comprehensive overview of the temporal and spatial dynamics of auxinregulated gene expression is lacking. Here, we analyze transcriptome data from many publicly available Arabidopsis profiling experiments and assess tissue-specific gene expression both in response to auxin concentration and exposure time and in relation to other plant growth regulators. Our analysis shows that the primary response to auxin over a wide range of auxin application conditions and in specific tissues comprises almost exclusively the up-regulation of genes and iden- tifies the most robust auxin marker genes. Tissue-specific auxin responses correlate with differential expression of Aux/ IAA genes and the subsequent regulation of context- and sequence-specific patterns of gene expression. Changes in transcript levels were consistent with a distinct sequence of conjugation, increased transport capacity and down-regulation of biosynthesis in the temperance of high cellular auxin concentrations. Our data show that auxin regulates genes associated with the biosynthesis, catabolism and signaling pathways of other phytohormones. We present a transcriptional overview of the auxin response. Specific interactions between auxin and other phytohormones are highlighted, particularly the regulation of their metabolism. Our analysis provides a roadmap for auxin-dependent processes that underpins the concept of an ＇auxin code＇-a tissue-specific fingerprint of gene expression that initiates specific developmental processes.

关键词： Alcohol Abstinence Genes transport capacity transcriptomics Tissue-Specific Gene Expression Auxins Arabidopsis Plant Growth Regulators

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光肩星天牛对干旱胁迫下复叶槭挥发物的嗅觉反应(英文)

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林业科学 2004年第1期40卷 99-105页

作者：金幼菊李继泉李建光骆有庆 stephen a.teale 北京林业大学生物中心北京100083 河北农业大学林业资源与工程学院保定074200 北京林业大学资源与环境学院北京100083 纽约州立大学环境科学与林业学院

对干旱胁迫下 3a生复叶槭的挥发物进行了鉴定。当复叶槭受到干旱胁迫时 ,9种化合物释放量升高 (包括 :丁醇、戊醇、反 - 2 -己烯 - 1-醛、顺 - 3-己烯 - 1-醇、戊醛、戊酸、己醛、己酸、苯乙酮 ) ,而长叶烯释放量降低。复叶槭复水后苯... 详细信息

对干旱胁迫下 3a生复叶槭的挥发物进行了鉴定。当复叶槭受到干旱胁迫时 ,9种化合物释放量升高 (包括 :丁醇、戊醇、反 - 2 -己烯 - 1-醛、顺 - 3-己烯 - 1-醇、戊醛、戊酸、己醛、己酸、苯乙酮 ) ,而长叶烯释放量降低。复叶槭复水后苯乙酮升高 ,但其他挥发物释放量降低。通过GC -EAD检测了光肩星天牛对其中某些化合物的触角电位反应 ,并使用诱捕器和人工合成单体进行了田间生测实验。丁醇、戊醇和顺 - 3-己烯 - 1-醇能引起光肩星天牛的触角反应 ,这一结果在田间实验中得到了证实。这表明干旱胁迫在光肩星天牛选择寄主植物方面起着重要作用。

关键词：光肩星天牛干旱胁迫复叶槭挥发物嗅觉反应

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Autosub6000:A Deep Diving Long Range AUV

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Journal of Bionic Engineering 2009年第1期6卷 55-62页

作者： stephen McPhail Underwater Systems Laboratory National Marine Facilities DivisionNational Oceanography CentreSouthampton SO14 3ZHUK

With an ultimate range up to 1000 km,a maximum operating depth of 6000 m,and a generous payload capacity,Autosub6000 is well placed to become one of the world's most capable deep diving Autonomous Underwater Vehicles(AUVs). Recently,Autosub6000 successfully completed its first deep water engineering trials,and in September 2008,fitted with a multibeam sonar,will carry out its first science *** paper will describe how we are tackling the design issues that specifically affect a deep diving AUV which must be capable of operating with true autonomy,independently of the mother ship, namely:carrying adequate energy for long endurance and range,coping with varying buoyancy,and maintaining accurate navigation throughout missions lasting up to several *** from the recent engineering trails are presented,and future missions and development plans are discussed.

关键词： AUV robotics navigation lithium polymer battery deep ocean research

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Auxin as a Model for the Integration of Hormonal Signal Processing and Transduction

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Molecular Plant 2008年第2期1卷 229-237页

作者： W.D. teale F.A. Ditengou A.D. Dovzhenko X. Li A.M. Molendijk B. Ruperti I. Paponov K. Palme Institute of Biology Ⅱ Faculty of Biology University of Freiburg D-79104 Freiburg Germanya Dipartimento di Agronomia Ambientale e Produzioni Vegetali Agripolis University of Padova viale dell'Universita 16 35020 Legnaro Italy

The regulation of plant growth responds to many stimuli. These responses allow environmental adaptation, thereby increasing fitness. In many cases, the relay of information about a plant＇s environment is through plant hormones. These messengers integrate environmental information into developmental pathways to determine plant shape. This re- view will use, as an example, auxin in the root ofArabidopsis thaliana to illustrate the complex nature of hormonal signal processing and transduction. It will then make the case that the application of a systems-biology approach is necessary, if the relationship between a plant＇s environment and its growth/developmental responses is to be properly understood.

关键词： .signaling molecules Plant hormones

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Palaeogeographic variation in the Permian-Triassic boundary microbialites:A discussion of microbial and ocean process esafter the end-Permian mass extinction

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Journal of Palaeogeography 2017年第2期6卷 97-107页

作者： stephen Kershaw Department of Life Sciences Brunel University Kingston Lane Uxbridge UB8 3PH UK

Shallow marine carbonate sediments that formed after the end-Permian mass extinction are rich in a thin(maximum ca.15 m) deposit of *** communities that constructed the microbialites have geographic variability of composition,broadly divisible into two groups:1) eastern Tethys sites are calcimicrobe-dominated(appearing as thrombolites in the field),with rare occurrence of sedimentconstructed microbialites and uncommon cements either within microbial structure or as inorganic precipitates,2) other Tethys sites are sediment-dominated structures forming stromatolites and thrombolites,composed of micrites and cements,with some inorganic *** other Tethys locations include western and central Tethys sites but their palaeogeographic positions depend on the accuracy of continental reconstructions,of which there are several *** contrast to geographic variation of microbialites,the conodont Hindeodus parvus,which appeared after the extinction and defines the base of the Triassic,is widespread,indicating easy lateral migration throughout *** animals were active nekton,although being small animals were presumably at least partly carried by water currents,implying active Tethyan surface water circulation after the extinction ***-extinction ammonoid taxa,presumed active swimmers,show poor evidence of a wide distribution in the Griesbachian beds immediately after the extinction,but are more cosmopolitan higher up,in the Dienerian strata in *** shelly fossils also have poorly defined distributions after the extinction,but ostracods show some wider distribution suggesting migration was possible after the *** there is a contrast between the geographic differences of microbialites and some shelly *** the cause of geographic variation of post-extinction microbialites is problematic and may include one or more of the following possibilities:1) because calcifying microbial organisms th

关键词： Stromatolite Thrombolite Microbialite Permian-Triassic boundary Conodonts Tethys Mass extinction

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Towards Second Green Revolution: Engineering Nitrogen Use Efficiency

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Journal of Genetics and Genomics 2014年第6期41卷 315-316页

作者： Klaus Palme Xugang Li William D.teale Institute of Biology II/Botany Faculty of Biology Albert-Ludwigs-University of Freiburg Schanzlestrasse 1 D-79104 Freiburg Germany Centre of Biological Systems Analysis Albert-Ludwigs-University of Freiburg Habsburgerstr. 49 D-79104 Freiburg Germany Freiburg Institute of Advanced Sciences (FRIAS) Albert-Ludwigs-University of Freiburg Albertstrasse 19 D-79104 Freiburg Germany Centre for Biological Signalling Studies (BIOSS) Albert-Ludwigs-University of Freiburg Schanzlestrasse 19D-79104 Freiburg Germany

Gaseous nitrogen （N2） makes up 78% of the earth＇s at- mosphere; its incorporation into a wide range of biological macromolecules molecules, such as nucleic acids and amino acids, makes it an essential part of all life on earth. However, as nitrogen gas is inert, it remains unavailable to most organisms, including plants. Thus, in order to be useful for fertilizer production, gaseous nitrogen needs first to be converted into bioavailable organic nitrogen in processes which are inefficient and rate-limiting for agricultural pro- duction. It was not until about 100 years ago that BASF were able to produce synthetic ammonia, the main ingredient for fertilizer production, on an industrial scale from pressurized air using the Haber--Bosch process. This chemical process was not only an impressive technical feat that helped Haber （1918） and Bosch （1931） earn Nobel Prizes but also enabled farmers to achieve the high yields that drive modern agriculture.

关键词： NUE Towards Second Green Revolution Engineering Nitrogen Use Efficiency RGA

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Combining Aluminum Heat Treat with Hot Isostatic Pressing: A Comparison of Structure, Properties, and Processing Routes for a Cast AI-Si-Mg Alloy

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材料热处理学报 2004年第5期25卷 546-551页

作者： stephen J. Mashl Body cote HIP Inc. Andover Massachusetts USA

Bodycote researchers have successfully demonstrated that a T6 heat treatment can be integrated with Densal?, a proprietary, aluminum specific, hot isostatic pressing (HIP) process. In this combined operation, at least a portion of the solution heat treatment is conducted at elevated pressure. During development, two issues, adiabatic cooling during depressurization and a possible variation in the kinetics of homogenization resulting from conducting the solution heat treat at elevated pressure were perceived as factors which could alter the heat treat response from that seen in conventional processing. This paper reviews the results of experiments performed to Al-Si-Mg (A356.0) castings subjected to both combined and conventional processing routes. Results indicate that the combined HIP and heat treat process is an efficient means of achieving a microstructure characteristic of a conventionally T6 processed material while eliminating porosity within the casting. Further, the fatigue life of an A356.0 casting processed using the combined cycle can be improved by more than an order of magnitude over the as-cast and T6 treated component.

关键词： Al-Si-Mg合金热处理热等静压缩 HIP 机械性质疲劳寿命

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