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Recent progress a.d trends in predictive visua. a.a.ytics

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Frontiers of Computer Science 2017年第2期11卷 192-207页

作者： Junhua.LU Wei CHEN Yuxin Ma.Junming KE Zongzhua.g LI Fa. ZHa.G ross Ma.IEJEWSKI Sta.e Key La. of Computer a.ded Design a.d Computer Gra.hics Zhejiang University Hangzhou 310058 China College of Science Zhejiang University of Technology Hangzhou 310023 China College of Computer Science a.d Technology Zhejiang University of Technology Hangzhou 310023 China School of Computing Informatics and Decision Systems Engineering Arizona State University Tempe AZ 85287-8809 USA

a.wide va.iety of predictive a.a.ytics techniques ha.e been developed in sta.istics, ma.hine lea.ning a.d da.a.mining; however, ma.y of these a.gorithms ta.e a.bla.k-box a.proa.h in which da.a.is input a.d future predictions a.e output with no insight into wha. goes on during the process. Unfortuna.ely, such a.closed system a.proa.h often lea.es little room for injecting doma.n expertise a.d ca. result in frustra.ion from a.a.ysts when results seem snurious or confusing. In order to a.low for more huma.-centric a.proa.hes, the visua.iza.ion community ha. begun developing methods to ena.le users to incorpora.e expert knowledge into the pre- diction process a. a.l sta.es, including da.a.clea.ing, fea.ure selection, model building a.d model va.ida.ion. This pa.er surveys current progress a.d trends in predictive visua. a.a. lytics, identifies the common fra.ework in which predictive visua. a.a.ytics systems opera.e, a.d develops a.summa.iza. tion of the predictive a.a.ytics workfiow.

关键词： predictive visua. a.a.ytics visua.iza.ion visua. a.a.ytics da.a.mining predictive a.a.ysis

Hepa.itis C in the pedia.ric popula.ion: Tra.smission, na.ura. history, trea.ment a.d liver tra.spla.ta.ion

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World Journa. of Ga.troenterology 2014年第32期20卷 11281-11286页

作者： Sa.ra.Kha.eri ross Shepherd John a.Goss Da.iel Leung Division of a.domina. Tra.spla.ta.ion Micheal E DeBakey Department of Surgery Baylor College of Medicine Houston TX 77030 United States Division of Pedia.ric Ga.troenterology Hepatology Nutrition Texas Children’s Hospital Baylor College of Medicine Houston TX 77030 United States

The number of children a.fected by the hepa.itis C virus (HCV) in the United Sta.es is estima.ed to be between 23000 to 46000. The projected medica. cost for children with HCV in the United Sta.es is upwa.ds of 200 million over the next deca.e. The implementa.ion of routine screening of blood supply ha. virtua.ly elimina.ed tra.smission via.tra.sfusion a.d vertica. tra.smission is now the most common mode of infection in children. Infections a.quired during infa.cy a.e more likely to sponta.eously resolve a.d fibrosis of the liver tends to increa.e with a.e suggesting slow progressive histologic injury. a.ti-vira. trea.ment ma. be wa.ra.ted in children with persistently eleva.ed liver enzymes or with significa.t fibrosis on liver biopsy. Current sta.da.d of ca.e includes weekly pegyla.ed interferon a.d riba.irin twice da.ly. Predictors of high susta.ned vira. response include genotype 2 a.d 3 a.d low vira. loa. in children with genotype 1 (a.y is a.socia.ed with a.significa.tly higher ra.e of susta.ned virologic response (> 90%). Only 34 pedia.ric pa.ients were tra.spla.ted with hepa.itis C between Ja.ua.y 2008 a.d a.ril 2013. The ma.ority of pedia.ric pa.ients were born prior to universa. screening of blood products a.d, a. of June 2013, there a.e only two pedia.ric pa.ients a.a.ting liver tra.spla.ta.ion for end-sta.e liver disea.e seconda.y to hepa.itis C. Pedia.ric surviva. ra.es post-tra.spla.t a.e excellent but gra.t surviva. is noticea.ly reduced compa.ed to a.ults (73.73% for pedia.ric pa.ients a. one yea. compa.ed to 87.69% in a.ult pa.ients). New sa.e potent, a.d a.l-ora. effective a.tivira. thera.ies for recurrent HCV should help increa.e gra.t surviva..

关键词： Hepa.itis C Liver tra.spla.ta.ion Pedia.ric Infection Fibrosis Liver disea.e

Bioa.tive polydimethylsiloxa.e surfa.e for optima. huma. mesenchyma. stem cell sheet culture

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Bioa.tive Ma.eria.s 2018年第2期3卷 167-173页

作者： Zichen Qia. Da.id ross Wenka. Jia.Qi Xing Feng Zha. Depa.tment of Biomedica. Engineering Michigan Technological University1400 Townsend DriveHoughtonMI 49931USA

Huma. mesenchyma. stem cell(hMSC)sheets hold grea. potentia. in engineering three-dimensiona.(3D)completely biologica. tissues for diverse *** cell sheet culturing methods employing thermoresponsive surfa.es a.e cost ineffective,a.d rely hea.ily on a.a.la.le *** this study,a.cost-effective method of la.er-by-la.er gra.ting wa. utilized for cova.ently binding a.homogenous colla.en I la.er on a.commonly used polydimethylsiloxa.e(PDMS)substra.e surfa.e in order to improve its cell a.hesion a. well a. the uniformity of the resulting hMSC cell *** showed tha. a.homogenous colla.en I la.er wa. obta.ned via.this gra.ting method,which improved hMSC a.hesion a.d a.ta.hment through relia.le colla.en I binding *** utilizing this low-cost method,a.uniform hMSC sheet wa. *** technology potentia.ly a.lows for ma.s production of hMSC sheets to fulfill the dema.d of thick hMSC constructs for tissue engineering a.d bioma.ufa.turing a.plica.ions.

关键词： Cell sheet engineering Huma. mesenchyma. stem cell Polydimethylsiloxa.e La.er-by-la.er gra.ting Cell a.hesion

Compa.a.ive scoping study report for the extra.tion of microa.ga. oils from two subspecies of Chlorella.vulga.is

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Clea. Energy 2020年第3期4卷 233-246页

作者： Ja.mine Kreft Eric Moe Nichola. Ga.cia.a.drew ross Wa.ne Sea.es Chemica. Engineering Depa.tment University of North Dakota243 Centennial Drive Stop 8155 Grand ForksND 58202USA School of Chemica. a.d Process Engineering University of Leeds209 Clarendon RoadLeedsLS29DTWest YorkshireUK

The production of microa.ga. a. a.fa.ty a.id oil resource for use in biofuels production is a.widesprea. resea.ch topic a. the la. *** conta.n a.higher lipid content on a.dry-weight ba.is compa.ed to oilseeds such a. ***,the growth a.d cultiva.ion cycle of microa.ga. is 15 da.s,in compa.ison to soybea.s,for which the cycle occurs once or twice ***,to da.e,it ha. been uneconomica. to produce microa.ga. oils in a.world-sca.e fa.ility due to limita.ions in cultiva.ing microa.ga. a. commercia. *** developments suggest tha. the use of heterotrophic microa.ga. ma. be economica.ly fea.ible for la.ge-sca.e oil *** a.sess this fea.ibility,a.compa.a.ive scoping study wa. performed a.a.ysing the fea.ibility of a. industria.-sca.e process pla.t for the growth a.d extra.tion of oil from *** were developed a. the prelimina.y design level using heterotrophic subspecies a.d a.totrophic subspecies of Chlorella.*** Cla.s 4 cost estima.es a.d economic a.a.yses were *** study concludes tha. processes ba.ed on heterotrophic microa.ga. a.e more likely to rea.h economic fea.ibility tha. processes using a.totrophic ***,a.few ba.riers still rema.n to a.hieving free-ma.ket economic via.ility.

关键词： a.ga. oil lipids process design heterotrophic microa.ga. prelimina.y design economic a.a.ysis

Fructose-sorbitol ingestion provokes ga.trointestina. symptoms in pa.ients with ea.ing disorders

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World Journa. of Ga.troenterology 2009年第42期15卷 5295-5299页

作者： Noel Friesen ross D Ha.sen Suza.ne F a.ra.a. John E Kellow Depa.tment of Obstetrics a.d Gyna.cology Royal North Shore HospitalUniversity of SydneySydney 2065Australia Depa.tment of Ga.troenterology Royal North Shore HospitalUniversity of SydneySydney 2065Australia

a.M:To eva.ua.e ga.trointestina.(GI) symptoms a.d brea.h hydrogen responses to ora. fructose-sorbitol(F-S) a.d glucose cha.lenges in ea.ing disorder(ED) ***:GI symptoms a.d hydrogen brea.h concentra.ion were monitored in 26 fema.e ED inpa.ients for 3 h,following ingestion of 50 g glucose on one da.,a.d 25 g fructose/5 g sorbitol on the next da.,a.ter a. overnight fa.t on ea.h *** to F-S were compa.ed to those of 20 a.ymptoma.ic hea.thy ***:F-S provoked GI symptoms in 15 ED pa.ients a.d one hea.thy control(P a.ient displa.ed symptom provoca.ion to glucose(P a.grea.er symptom response wa. observed in ED pa.ients with a.body ma.s index(BMI) ≤ 17.5 kg/m 2 compa.ed to those with a.BMI > 17.5 kg/m 2(P a. scores,preva.ence of functiona. GI disorders or brea.h hydrogen responses between pa.ients with a.d without a. F-S ***:F-S,but not glucose,provokes GI symptoms in ED pa.ients,predomina.tly those with low *** findings a.e importa.t in the dieta.y ma.a.ement of ED pa.ients.

关键词： Fructose Sorbitol Ma.a.sorption syndromes Functiona. ga.trointestina. disorders Ea.ing disorders Underweight

Shelley a.d the a.prehension of life

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Shelley and the apprehension of life

作者： (1979-)Wilson ross

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作者： Posnock ross.

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Future fa.ilies

Pyogenic liver a.scess:a. a.dit of 10 yea.s’experience

作者： Pa.ke ross D.

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World Journa. of Ga.troenterology 2011年第12期17卷 1622-1630页

作者： Tony CY Pa.g Thoma. Fung Ja.winder Sa.ra.Thoma. J Hugh ross C Smith Upper Ga.trointestina. Surgica. Unit Royal North Shore HospitalUniversity of SydneySt Leonards NSW 2065Australia

a.M:To describe our own experience with pyogenic liver a.scesses over the pa.t 10 yea.s a.d investiga.e the risk fa.tors a.socia.ed with fa.lure of initia. percuta.eous ***:a.retrospective study of records of 63 PLa.pa.ients presenting between 1998 a.d 2008 to a.stra.ia. tertia.y referra. centre,were *** a.d hyda.id a.scesses were ***,clinica.,ra.iologica.,a.d microbiologica. cha.a.teristics,a. well a. surgica./ra.iologica. interventions,were ***:Sixty-three pa.ients(42 ma.es,21 fema.es) a.ed 65(±14) yea.s[mea.±(SD) ]ha. prodroma. symptoms for a.media.(interqua.tile ra.ge;IQR) of 7(5-14) *** 59%of pa.ients were febrile a. presenta.ion;however,the serum C-rea.tive protein wa. eleva.ed in a.l 47 in whom it wa. *** function tests were non-specifica.ly a.norma..67%of pa.ients ha. a.solita.y a.scess,while 32%ha.>3 a.scesses with a.media.(IQR) dia.eter of 6.3(4-9) *** orga.isms were:Streptococcus milleri 25%,Klebsiella.pneumonia. 21%,a.d Escherichia.coli 16%.a.presumptive cryptogenic ca.se wa. most common (34%).Four pa.ients died in this series:one from sepsis,two from a.va.ced ca.cer,a.d one from a.ute myoca.dia. *** initia. procedure wa. ra.iologica. a.pira.ion±dra.na.e in 54 a.d surgery in two pa.ients.17%underwent surgica. ma.a.ement during their *** hypoa.bumina.mia.mea. (95%CI) :32(29-35) g/L vs 28(25-31) g/L,P=0.045] on presenta.ion wa. found to be the only fa.tor rela.ed to fa.lure of initia. percuta.eous thera.y on univa.ia.e ***:PLa.is a.dia.nostic cha.lenge,beca.se the presenta.ion of this condition is *** a.tibiotics a.d ra.iologica. dra.na.e in the first insta.ce a.lows resolution of most PLa.;However,a.sma.l proportion of pa.ients still require surgica. dra.na.e.

关键词： Pyogenic liver a.scess Ima.e guided dra.na.e Surgica. dra.na.e C-rea.tive protein Hypoa.bumina.mia