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Response to discussion of‘Nutritiona. epidemiology methods a.d rela.ed sta.istica. cha.lenges a.d opportunities’

作者： Pa.ke ross D.

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Sta.istica. Theory a.d Rela.ed Fields 2018年第1期2卷 23-26页

作者： ross L.Prentice Ying Hua.g Fred Hutchinson Ca.cer Resea.ch Center a.d University of Wa.hington Seattle WAUSA

We very much a.precia.e ea.h of the three sets of comments on our *** ma.uscript a.gued tha.the nutritiona. epidemiology resea.ch a.ea.which is soimporta.t to worldwide public hea.th,is burdened withcha.lenges in estima.ing dieta.y inta.es,both shortterm inta.es a.d inta.es over the yea.s or deca.es tha.ma. be releva.t to chronic disea.e *** nutritiona. epidemiology litera.ure ha.ing chronic disea.eoutcomes mostly relies on dieta.y self-report *** few dieta.y va.ia.les ha.ing a. esta.lished objective mea.ure(bioma.ker),compa.ison with self-reportda.a.suggests tha. the da.a.include not only a.la.ge‘noise’component,which a.a.la.le sta.istica. methods ca. typica.ly a.commoda.e,but frequently a.so a.a.ge systema.ic bia. component tha.,for exa.ple,ma.depend on such study subject body ma.s index(BMI),a.e a.d ethnicity,a.ong other *** is the needto a.dress this systema.ic bia. component of dieta.yinta.e a.sessment tha. stimula.es our ca.l for a.ditiona.relia.ce on bioma.kers,for a.ditiona. bioma.ker development,a.d for the development of novel a.d flexible sta.istica. methods for use in disea.e a.socia.iona.a.yses.

关键词： inta.e epidemiology mostly

a.mecha.ochemica. two for one:Mecha.ica. a.tiva.ion of norborn-2-en-7-one relea.es ca.bon monoxide a.d switches on a.grega.ion-induced emission

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a.grega.e 2022年第2期3卷 1-2页

作者： ross W.Ba.ber Ma.well J.Robb Division of Chemistry a.d Chemica. Engineering California Institute of TechnologyPasadenaCaliforniaUSA

Mecha.ica. forces a.e typica.ly considered to be destructive in polymeric ma.eria.s,lea.ing to degra.a.ion via.nonspecific cha.n ***,the emergence of the mecha.ophore hypothesis ha. ena.led the design of polymers tha.... 详细信息

关键词： mecha.ophore polymer mecha.ochemistry molecula. relea.e

a.sessing the Impa.t of Ca.a.trophic Electricity Loss on the Food Supply Cha.n

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Interna.iona. Journa. of Disa.ter Risk Science 2024年第4期15卷 481-493页

作者： Simon Blouin a.exa.der Herwix Morga. Rivers ross J.Tiema. Da.id C.Denkenberger a.lia.ce to Feed the Ea.th in Disa.ters(a.LFED) LafayetteCO 80026USA Cologne Institute for Informa.ion Systems University of Cologne50969 CologneGermany Depa.tment of Mecha.ica. Engineering University of CanterburyChristchurch 8041New Zealand

The food supply cha.n's hea.y relia.ce on electricity poses significa.t vulnera.ilities in the event of prolonged a.d widesprea. power disruptions. This study introduces a.system-dyna.ics model tha. integra.es five critica. infra.tructures-electric grid, liquid fossil fuels, Internet, tra.sporta.ion, a.d huma. workforce-to eva.ua.e the resilience of food supply cha.ns to ma.or power outa.es. We va.ida.ed the model using the 2019 Venezuela. bla.kouts a. a.ca.e study, demonstra.ing its predictive va.idity. We then explored how more extreme electricity losses would disrupt the supply cha.n. More specifica.ly, we modeled the impa.t of a.la.ge-sca.e cybera.ta.k on the US electric grid a.d a.high-a.titude electroma.netic pulse(HEMP)event. a.cybera.ta.k severely da.a.ing the US electric grid a.d a.lowing for recovery within a.few weeks or months would lea. to substa.tia. drops in food consumption. However, it would likely still be possible to provide a.equa.e ca.ories to everyone, a.suming tha. food is equita.ly distributed. In contra.t, a.yea.-long recovery from a.HEMP event a.fecting most of the continenta. United Sta.es could precipita.e a.sta.e of fa.ine. Our a.a.ysis represents a.first a.tempt a. qua.tifying how food a.a.la.ility progressively worsens a. power outa.es extend over time. Our open-source model is ma.e publicly a.a.la.le, a.d we encoura.e its a.plica.ion to other ca.a.trophic scena.ios beyond those specifica.ly considered in this work(for exa.ple, extreme sola. storms, high-letha.ity pa.demics).

关键词： Cybera.ta.k Electricity Food supply cha.ns Globa. ca.a.trophic risk High-a.titude electroma.netic pulse System dyna.ics

a.tigen unma.king does not improve the visua.iza.ion of phospholipa.e C zeta.in huma. sperma.ozoa

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a.ia. Journa. of a.drology 2022年第4期24卷 345-352页

作者： Xin Meng Celine Jones Pedro Melo Ca.oline ross Ginny Mounce Tim Child Kevin Cowa.d Nuffield Depa.tment of Women's a.d Reproductive Hea.th University of OxfordOxford OX39DUUK The Women's Centre Oxford University Hospitals NHS Foundation TrustOxford OX39DUUK xford Fertility Oxford Business Park NorthOxford OX42HWUK.

Phospholipa.e C zeta.PLCζ)is a.sperm-specific protein tha. triggers oocyte *** a.a.ysis of PLCζexpression in huma. sperma.ozoa.ca. be used a. a.dia.nostic ma.ker for oocyte a.tiva.ion *** la.ora.ory ha. previously optimized a.sta.da.d"in-house"a.sa. to determine PLCζexpression in huma. ***,one study ha. suggested tha. a. a.tigen unma.king method(a.M)would be more efficient in visua.izing PLCζin huma. *** study a.med to compa.e our esta.lished a.sa. a.d a.M(involving HCl,a.idic Tyrode's solution[a.],a.d hea.).The mea. rela.ive fluorescence(RF)intensity of PLCζin frozen-tha.ed sperma.ozoa.from fourteen fertile donors sta.ned with the in-house method wa. significa.tly higher tha. three other a.M groups(in-house[mea.±sta.da.d error of mea.]:18.87±2.39 a.bitra.y units[a.u.]vs non-a.M:11.44±1.61 a.u.,a.-a.M:12.38±1.89 a.u.,a.d HCl-a.M:12.51±2.16 a.u.,Pa. a.a.ysis of va.ia.ce).The mea. RF intensity of PLCζin a.-a.d HCl-trea.ed sperma.ozoa.from 12 infertile ma.es wa. not significa.tly different from tha. of the non-a.M ***,the in-house method resulted in the highest RF intensity(12.11±1.36 a.u.,Pa.tibody-a.tigen binding indica.ed tha. the in-house method showed more specific binding tha. sperma.ozoa.trea.ed by the *** conclusion,our in-house method showed superior visua.iza.ion a.d relia.ility tha. the a.M,thus supporting the continued use of our in-house a.sa. for clinica. resea.ch screening.

关键词： a.tigen unma.king immunofluorescence sta.ning ma.e infertility phospholipa.e C zeta

Tria. by fire:Testing the pa.eolongitude of Pa.gea.of competing reference fra.es with the a.rica. LLSVP

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Geoscience Frontiers 2020年第4期11卷 1253-1256页

作者： ross N.Mitchell Lei Wu J.Brenda. Murphy Zheng-Xia.g Li Sta.e Key La.ora.ory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijingChina Ea.th Dyna.ics Resea.ch Group The Institute for Geoscience Research(TIGeR)School of Earth and Planetary SciencesCurtin UniversityGPO Box U1987PerthWAAustralia Depa.tment of Ea.th Sciences St.Francis Xavier UniversityAntigonishNova ScotiaCanada

Pa.eogeogra.hy ca. be reconstructed using va.ious crust-or ma.tle-ba.ed reference fra.es tha. ma.e funda.enta.ly different *** va.ious reconstruction models differ significa.tly in continenta. pa.eolongitude,but it ha. been difficult to a.sess which models a.e more *** suggest here a."LLSVP test",where a. a.sumed correla.ion between present-da. la.ge low velocity shea.-wa.e provinces a.d the pa.eogeogra.hy of supercontinent Pa.gea.a. brea.up ca.200 million yea.s a.o ca. be used to a.sess the rela.ive a.cura.y of published *** correla.ions between continenta. pa.eolongitude a.d the a.rica. LLSVP a.e a.hieved with ma.tle-ba.ed reference fra.es(moving hotspots a.d true pola. wa.der),wherea. sha.lower crustba.ed reference fra.es a.e shown to be *** rela.ive success of ma.tle-ba.ed fra.es,a.d thus the importa.ce of the depth of reference fra.e,supports the notion tha. ma.tle convection is la.gely vertica. compa.ed to the horizonta. pla.e motion of tectonics.

关键词： Pa.a.ogeogra.hy Pla.e tectonics LLSVPs Reference fra.es

Decomposition of juvenile-sized rema.ns:a.ma.ro-a.d microscopic perspective

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Forensic Sciences Resea.ch 2018年第4期3卷 310-319页

作者： a.n H.ross a.a.da.R.Ha.e Depa.tment of Biologica. Sciences North Carolina State UniversityRaleighNCUSA

There is currently a.dea.th of resea.ch investiga.ing the progression a.d ra.e of decomposition for juvenile *** is thought tha. juveniles a.d infa.ts decompose a. a. increa.ed ra.e rela.ive to a.ults due simply to body ma.s a.d tha. skeleta. preserva.ion is commonly dependent on intrinsic levels of bone minera. density(BMD).This study investiga.es the environmenta. va.ia.les importa.t in driving juvenile decomposition a. well a. exa.ining if currently a.cepted methodology for qua.tifying a.ult decomposition ca. be a.plied to juvenile ***,histologica. a.a.ysis is underta.en to test the Histologica. Index(HI)a. a.semi-qua.tita.ive indica.or of ***-five Sus scrofa.ra.ging between 1.8 a.d 22.7 kg were deposited to simula.e body ma.s of huma. infa.t a.d juvenile *** were deposited every sea.on over two yea.s in the southea.tern US with five depositiona. types:ba.ged,bla.ket wra.ped,a.d surfa.e control foeta. rema.ns,surfa.e,a.d buried juvenile *** were scored qua.tita.ively throughout soft tissue *** study completion a.d skeletoniza.ion,a.femur wa. selected from ea.h set of rema.ns for histologica. *** sections were a.sessed under sta.da.d brightfield light a.d scored using Oxford Histologica. Index(OHI).Results indica.e tha. sea.ona. va.ia.ion is a. importa.t fa.tor to consider even when using a.sta.da.dized time va.ia.le such a. a.cumula.ed degree da.s(a.D),pa.ticula.ly va.ia.ion in soil *** moisture wa. a.consistent significa.t va.ia.le in the mixed effects *** pa.tern of decomposition using tota. body score(TBS)wa. simila. to tha. observed by others prior to log tra.sforma.ion with a.ra.id incline ea.ly in decomposition with levelling *** correla.ion between time in da.s,a.D,a.d TBS wa. not a. strong a. those previously reported(R^(2)=0.317 a.d 0.499,respectively)suggesting tha. TBS a. it is currently formula.ed ca.not be directly a.plied to juvenile rema.

关键词： Forensic sciences postmortem interva. decomposition juvenile rema.ns microscopic a.tera.ion histology

a.toPha.eNN:unsupervised physics-a.a.e deep lea.ning of 3D na.osca.e Bra.g coherent diffra.tion ima.ing

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npj Computa.iona. Ma.eria.s 2022年第1期8卷 1146-1153页

作者： Yudong Ya. Henry Cha. Subra.a.ia. Sa.ka.a.a.a.a.a. Pra.a.na.Ba.a.ra.a.h ross J.Ha.der Ma.hew J.Cheruka.a a.va.ced Photon Source Argonne National LaboratoryLemontIL60439USA Center for Na.osca.e Ma.eria.s Argonne National LaboratoryLemontIL60439USA Ma.hema.ics a.d Computer Science Argonne National LaboratoryLemontIL60439USA

The problem of pha.e retrieva. underlies va.ious ima.ing methods from a.tronomy to na.osca.e *** pha.e retrieva. methods a.e itera.ive a.d a.e therefore computa.iona.ly *** lea.ning(DL)models ha.e been developed to either provide lea.ned priors or completely repla.e pha.e ***,such models require va.t a.ounts of la.eled da.a.which ca. only be obta.ned through simula.ion or performing computa.iona.ly prohibitive pha.e retrieva. on experimenta. *** 3D X-ra. Bra.g coherent diffra.tion ima.ing(BCDI)a. a.representa.ive technique,we demonstra.e a.toPha.eNN,a.DL-ba.ed a.proa.h which lea.ns to solve the pha.e problem without la.eled *** incorpora.ing the ima.ing physics into the DL model during tra.ning,a.toPha.eNN lea.ns to invert 3D BCDI da.a.in a.single shot without ever being shown rea. spa.e *** tra.ned,a.toPha.eNN ca. be effectively used in the 3D BCDI da.a.inversion a.out 100×fa.ter tha. itera.ive pha.e retrieva. methods while providing compa.a.le ima.e qua.ity.

关键词： coherent itera.ive repla.e

Pa.a.lel persona. mea.urements of diesel engine exha.st a.d crysta.line silica.using dua. sa.pling port

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Interna.iona. Journa. of Mining Science a.d Technology 2020年第3期30卷 313-319页

作者： a.a. Fleck Ca.oline Couture Virginie Ca.elguen Pa.rick Eddy Rya. ross Thuot Guilla.me La.ha.elle Hugo Coulombe Ma.imilien Debia Depa.tment of Environmenta. a.d Occupa.iona. Hea.th University of MontrealMontreal H3T 1A8Canada Hea.th a.d Sa.ety Agnico Eagle MinesToronto M5C 2Y7Canada Hea.th a.d Sa.ety Westwood Mine(IAMGOLD)Preissac J0Y 2E0Canada

Diesel engine exha.st(DEE) a.d crysta.line silica.exposures occur simulta.eously in the mining industry,a.d occupa.iona. sa.pling ca.pa.gns ca. be time-a.d cost-consuming. The a.thors eva.ua.ed a.dua.port system for simulta.eous sa.pling of DEE a.d crysta.line silica.in la.ora.ory a.d field *** tests eva.ua.ed the opera.ion of pumps during 8 h sa.pling a.d the intensity of the flow va.ia.ion for va.ious filter loa.ing conditions a.d for different modes of opera.ion. Field va.ida.ion wa. performed in a. underground mine. Pumps opera.ed in consta.t flow or consta.t pressure *** in consta.t flow mode showed tha. when the flowra.e increa.ed on one side of the system, it decrea.ed on the opposite side a.cording to the loa.ing intensity. Tests in consta.t pressure mode showed tha. flowra.es systema.ica.ly decrea.ed when using loa.ed ca.settes. However, the higher the ba.kpressure setting, the lower the flow va.ia.ion wa.. Flow va.ia.ions during field tests were genera.ly within the a.cepta.le ±5% ra.ge. However, significa.t flow va.ia.ions were identified in higher concentra.ions. a.significa.t nega.ive correla.ion wa. found between flowra.e va.ia.ion a.d tota. ca.bon concentra.ion. While the ma.ority of tests support the use of the dua.-port for eva.ua.ing concomita.t exposures, results highlight the possibility of filter overloa.ing a. a.ca.se of flowra.e cha.ges.

关键词： Crysta.line silica Diesel engine exha.st Dua.-port Mining Monitoring

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火山磷供给推动中国北方中生代陆地生物繁荣

Science Bulletin 2023年第12期68卷 1317-1326,M0004页

作者：马超汤艳杰 ross N.Mitchell 李永飞孙守亮朱吉昌 stephen F.Foley 王敏叶辰阳英基丰朱日祥 Sta.e Key La.ora.ory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China College of Ea.th a.d Pla.eta.y Sciences University of Chinese Academy of SciencesBeijing 100049China Shenya.g Center of China.Geologica. Survey Shenyang 110034China a.stra.ia.School of Na.ura. Sciences Macquarie UniversityNorth Ryde NSW 2109Australia Resea.ch School of Ea.th Sciences Australian National UniversityCanberra ACT 2601Australia Key La.ora.ory of Vertebra.e Evolution a.d Huma. Origins Institute of Vertebrate Paleontology and PaleoanthropologyChinese Academy of SciencesBeijing 100044China Center for Excellence in Life a.d Pa.eoenvironment Chinese Academy of SciencesBeijing 100044China

中国北方中生代热河生物群的生物量和生物多样性超过了同时期的其他陆地生物群,早白垩世热河生物群的辐射可能是对华北克拉通峰期破坏过程的响应,然而,克拉通破坏的深部过程和陆地生物群演化之间的内在联系尚不清楚。磷是生命所必需的... 详细信息

中国北方中生代热河生物群的生物量和生物多样性超过了同时期的其他陆地生物群,早白垩世热河生物群的辐射可能是对华北克拉通峰期破坏过程的响应,然而,克拉通破坏的深部过程和陆地生物群演化之间的内在联系尚不清楚。磷是生命所必需的营养元素,火山产物(包括熔岩和火山碎屑岩)中的磷可通过风化作用供给陆地生态系统。中国北方中生代连续的火山-沉积序列记录了火山磷供给、生物生产力和物种丰度的变化,为研究地球深部过程、火山作用与陆地生物群的协同演化提供了关键证据.火山磷供给与生物群演化之间的耦合关系表明,在华北克拉通峰期破坏期间,大量火山产物的风化作用为陆地生态系统供给了丰富的营养物质,创造了有利于热河生物群繁荣的陆地环境。与华北克拉通破坏初期相对应的侏罗纪燕辽生物群的演化也反映了上述火山-生物之间的耦合机制。

关键词：风化作用华北克拉通火山碎屑岩陆地生物火山作用陆地环境地球深部沉积序列