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Prader-Willi Syndrome and the Use of Medical Nutrition Therapy

2005年

作者： stephen brown Zvonko Vranesic.

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Case Reports in Clinical Medicine 2024年第8期13卷 339-344页

作者： Alexis Howarth Cameron Carroll Madison Battersby stephen brown JuliSu DiMucci-Ward Department of Nutrition Edward Via College of Osteopathic Medicine Spartanburg South Carolina USA

Title: Integrating Consistent Individualized Carbohydrate-Controlled Anti- Inflammatory Nutritional Plan (C-ICAN) in the Management of Prader-Willi Syndrome: A Case Report. Prader–Willi syndrome (PWS) is a rare genetic disorder caused by a loss of function of specific genes on chromosome 15. Patients with this disease present unique challenges in management, particularly regarding obesity and nutritional regulation as the disease symptoms change depending on the age of the patient and the phase of the disease. These challenges pose critical stressors to caregivers and their families. We present a case report of a 5-year-old Caucasian male diagnosed with PWS, exhibiting failure to thrive and uncontrolled weight gain. His caregiver was his elderly grandmother who, by her own admission, was ill-equipped to deal with the patient’s physical symptoms and his behavior in response to dietary restrictions. Through a multidisciplinary approach involving medical nutrition therapy (MNT) involving the implementation of a Consistent Individualized Carbohydrate-Controlled Anti-Inflammatory Nutritional plan (C-ICAN), growth hormone supplementation, and behavioral interventions patient markedly improved physically and emotionally.

关键词： Prader-Willi Syndrome Growth Hormone Medical Nutrition Therapy Eating Control Obesity

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数字逻辑与VHDL设计 4

Symptom presentation and evolution in the first 48 hours after injury are associated with return to play after concussion in elite Rugby Union

丛书名： VHDL与集成电路设计丛书

2005年

作者： stephen brown Zvonko Vranesic

本书把数字逻辑设计、VHDL描述以及使用CAD工具三者结合，帮助读者高效地完成一个设计。附有一张光盘，该软件工具可以把一个用VHDL描述的设计自动映射到可编程器件。

ISBN: (纸本)7894942987

关键词： VHDL语言

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Journal of Sport and Health Science 2024年第3期13卷 387-397页

作者： Ross Tucker Matt Cross Keith Stokes Lindsay Starling Rosy Hyman Simon Kemp stephen West Martin Raftery Eanna Falvey James brown Institute of Sport and Exercise Medicine(ISEM) Department of ExerciseUniversity of StellenboschTygerberg 7505South Africa World Rugby Ltd. Dublin D02 AE93Ireland Premiership Rugby London SW1V 1PXUK Centre for Health and Injury and Illness Prevention in SportUniversity of BathClaverton Down BA27AYUK UK Collaborating Centre on Injury and Illness Prevention in Sport(UKCCIIS) University of BathClaverton Down BA27AYUK Rugby Football Union London TW27BAUK London School of Tropical Medicine London WC1E 7HTUK Sport Injury Prevention Research Centre Faculty of KinesiologyUniversity of CalgaryCalgary T2N 1N4Canada Department of Medicine School of Medicine and HealthUniversity College CorkCork T12 EC8PIreland Carnegie Applied Rugby Research(CARR)centre Carnegie School of SportLeeds Beckett UniversityLeeds LS63QSUK

Background:Return to play(RTP)in elite rugby is managed using a 6-stage graduated RTP protocol,which can result in clearance to play within 1 week of *** aimed to explore how symptom,cognitive,and balance presentation and evolution during concussion screens 2 h(head injury assessment(HIA2)and 48 h(HIA3)after injury were associated with time to RTP)to identify whether a more conservative graduated RTP may be ***:A retrospective cohort study was conducted in 380 concussed rugby players from elite men’s rugby over 3 consecutive *** were classified as shorter or longer returns,depending on whether RTP occurred within 7 days(allowing them to be considered to play the match 1 week after injury)or longer than 8 days,***,cognitive,and balance performance during screens was assessed relative to baseline(normal or abnormal)and to the preceding screen(improving or worsening).Associations between sub-test abnormalities and RTP time were explored using odds ratios(OR,longer ***).Median day absence was compared between players with abnormal or worsening results and those whose results were normal or ***:Abnormal symptom results during screens 2 h and 48 h after concussion were associated with longer return time(HIA2:OR=2.21,95%confidence interval(95%CI):1.39-3.50;HIA3:OR=3.30,95%CI:1.89-5.75).Worsening symptom number or severity from the time of injury to 2 h and 48 h post-injury was associated with longer return(HIA2:OR=2.49,95%CI:1.36-4.58;HIA3:OR=3.34,95%CI:1.10-10.15).Median days absence was greater in players with abnormal symptom results at both HIA2 and *** and balance performance were not associated with longer return and did not affect median days ***:Symptom presentation and evolution within 48 h of concussion were associated with longer RTP *** may guide a more conservative approach to RTP,while still adhering to individualized concussion management principles.

关键词： Brain injury Concussion management General return to play Medical management

循环荷载下柔性路面路基变形的动力耦合分析(英文)

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岩土工程学报 2001年第6期23卷 757-762页

作者：黄雨 stephen F brown Glenn R Mcdowell Department of Geotechnical Engineering Tongji Universit y School of Civil Engineering University of Nottingh am Nottingham NG7 2RDU.K.

首先简要综述了循环荷载下路基变形的研究现状。然后 ,基于饱和土体的动力耦合分析理论 ,研究了平面应变条件下的柔性路面路基变形的数值分析模型和方法 ,并建立了一个简单的粘弹性动力计算模型来预测路基在循环荷载下的动力反应。该模... 详细信息

首先简要综述了循环荷载下路基变形的研究现状。然后 ,基于饱和土体的动力耦合分析理论 ,研究了平面应变条件下的柔性路面路基变形的数值分析模型和方法 ,并建立了一个简单的粘弹性动力计算模型来预测路基在循环荷载下的动力反应。该模型可以全面考虑路基材料的剪切模量、阻尼比、孔隙水压力以及永久变形。最后 ,以一个柔性路面为例 ,应用本文方法在循环荷载下的路基变形发展进行了分析。

关键词：车辙柔性路面路基变形动力耦合分析循环荷载

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上海商贸的后世博发展

国际商业技术 2010年第6期 26-29页

作者： stephen brown[英] 朱娱（翻译）银硃合伙人有限公司不详

首先，祝贺2010年上海世博会圆满成功，这是历史上最为杰出的一届世博会，尤其是在世界经济处于80年来最为低迷的时期，取得如此巨大的成就实属不易。

关键词： 2010年上海世博会商贸世界经济低迷

Fundamentals of digital logic with VHDL design

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Fundamentals of digital logic with VHDL design

DEM investigation of strength and critical state behaviours of granular materials under true triaxial loadings

2005年

作者： stephen D. brown Zvonko G. Vranesic.

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Particuology 2024年第2期85卷 198-212页

作者： Minyi Zhu Guobin Gong Jun Xia stephen Wilkinson Department of Civil Engineering Xi'an Jiaotong-Liverpool UniversityChina Department of Civil Engineering and Industrial Design University of LiverpoolLiverpoolUK Faculty of Engineering and Information Sciences University of Wollongong in DubaiUnited Arab Emirates

This paper investigates the strength and critical state(CS)behaviours of granular materials via DEM simulations of true triaxial drained tests under three different loading modes including constant b(in-termediate stress ratio)tests with constantσ'1(major principal stress),constant p(mean pressure)and constantσ'3(minor principal stress)*** this end,a series of samples are generated with the same particle size distribution,and with the confining stresses ranging from 100 kPa to 900 *** CS is achieved for all *** the macroscopic behaviours and the microscopic behaviours are examined and compared considering different loading modes,confining stresses and intermediate stress ratios(b).The critical state lines(CSLs)are found to be unique and independent of the loading modes,but dependent on the b *** CSLs with b=0 and b=1 form the two boundaries of CSLs respectively beyond which CSLs under all other b tests cannot go *** different strength criteria are examined and compared in terms of both peak and CS *** Mohr-Coulomb strength criterion is found to be only suitable for axisymmetric loading *** Lade-Duncan criterion is only suitable for describing peak strengths,which is dependent on the loading modes and confining *** Satake criterion and Matsuoka-Nakai criterion are the more appropriate strength criteria for describing CS failures,indicating that the CS values of both the Satake parameter and the Matsuoka-Nakai parameter describe an inherent property that characterizes the CS failure for a given type of *** CS mechanical coordination number is fitted by a curved line for a given b value,which is unique regardless of the loading *** peak and CS values of both major and minor principal fabric tensors decrease with increasing b values,while they increase with increasing b values for the intermediate principal fabric tensor.

关键词： Discrete element method Intermediate stress ratio Dilation Critical state Failure criterion

今日世界的竞争之道——英国的经验供上海借鉴

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国际商业技术 2012年第3期 20-23页

作者： Sir stephen brown[英] 朱娱（全译）英国ADRg Ambassadors公司不详

面对全球经济不确定性增多的形势，中国作为世界第二大经济体在全球扮演更为重要的角色。中英两国频繁的交流增进了相互依存，合作机会众多。在建设国际贸易中心过程中，应当在规范执法、保护知识产权、市场准入、增加公平性、提高透明... 详细信息

面对全球经济不确定性增多的形势，中国作为世界第二大经济体在全球扮演更为重要的角色。中英两国频繁的交流增进了相互依存，合作机会众多。在建设国际贸易中心过程中，应当在规范执法、保护知识产权、市场准入、增加公平性、提高透明度等方面做出进一步改善．

关键词：英国中国经济形势相互依存法律法规改善

DCFNet:Discriminant Correlation Filters Network for Visual Tracking

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Journal of Computer Science & Technology 2024年第3期39卷 691-714页

作者：胡卫明王强高晋李兵 stephen Maybank State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of AutomationChinese Academy of Sciences Beijing 100190China Department of Computer Science and Information Systems Birkbeck CollegeLondon WC1E 7HXU.K.

CNN(convolutional neural network)based real time trackers usually do not carry out online network update in order to maintain rapid tracking *** inevitably influences the adaptability to changes in object *** filter based trackers can update the model parameters online in real *** this paper,we present an end-to-end lightweight network architecture,namely Discriminant Correlation Filter Network(DCFNet).A differentiable DCF(discriminant correlation filter)layer is incorporated into a Siamese network architecture in order to learn the convolutional features and the correlation filter *** correlation filter can be efficiently updated *** previous work,we introduced a joint scale-position space to the DCFNet,forming a scale DCFNet which carries out the predictions of object scale and position *** combine the scale DCFNet with the convolutional-deconvolutional network,learning both the high-level embedding space representations and the low-level fine-grained representations for *** adaptability of the fine-grained correlation analysis and the generalization capability of the semantic embedding are complementary for visual *** back-propagation is derived in the Fourier frequency domain throughout the entire work,preserving the efficiency of the *** evaluations on the OTB(Object Tracking Benchmark)and VOT(Visual Object Tracking Challenge)datasets demonstrate that the proposed trackers have fast speeds,while maintaining tracking accuracy.

关键词： correlation filter convolutional neural network(CNN) visual tracking