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Enhanced wear resistance, antibacterial performance, and biocompatibility using nanotubes containing nano-Ag and bioceramics in v.tro

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BIO-DESIGN AND MANUFACTURING 2024年第5期7卷 670-686页

作者： Wang, Qingge Liu, Jia Wu, Hong Liu, Jingbo Ren, Yaojia Liang, Luxin Yan, Xinxin Baker, Ian Liu, Shifeng Uglov. v. v. Yang, Chengliang Wang, Liqiang Cent South Univ State Key Lab Powder Met Changsha 410083 Peoples R China Youjiang Med Univ.Nationalities Guangxi Zhuang Autonomous Reg Engn Res Ctr Biomat Guangxi Key Lab Preclin & Translat Res Bone & Join Guangxi Key Lab Biomed Mat ResAffiliated Hosp Baise 533000 Peoples R China Cent South Univ Xiangya Hosp 2 Dept Orthoped Changsha 410011 Peoples R China Wuhan Univ Renmin Hosp Dept Orthoped Wuhan 430060 Peoples R China Dartmouth Coll Thayer Sch Engn Hanover NH 03755 USA Xian Univ.Architecture & Technol Sch Met Engn Xian 710055 Peoples R China Belarusian State Univ Minsk 220030 BELARUS Shanghai Jiao Tong Univ Sch Mat Sci & Engn State Key Lab Met Matrix Composites Shanghai 200240 Peoples R China

A good Ti-based joint implant should prev.nt stress shielding and achiev. good bioactiv.ty and anti-infection performance. To meet these requirements, the low-elastic-modulus alloy-Ti-35Nb-2Ta-3Zr-was used as the substrate, and functional coatings that contained bioceramics and Ag ions were prepared for coating on TiO2 nanotubes (diameter: (80 +/- 20) nm and (150 +/- 40) nm) using anodization, deposition, and spin-coating methods. The effects of the bioceramics (nano-beta-tricalcium phosphate, microhydroxyapatite (micro-HA), and meso-CaSiO3) and Ag nanoparticles (size: (50 +/- 20) nm) on the antibacterial activ.ty and the tribocorrosion, corrosion, and early in v.tro osteogenic behav.ors of the nanotubes were inv.stigated. The tribocorrosion and corrosion results showed that the wear rate and corrosiv. rate were highly dependent on the features of the nanotube surface. Micro-HA showed great wear resistance with a wear rate of (1.26 +/- 0.06)x10-3 mm3/(N center dot m) due to adhesiv. and abrasiv. wear. Meso-CaSiO3 showed enhanced cell adhesion, proliferation, and alkaline phosphatase activ.ty. The coatings that contained nano-Ag exhibited good antibacterial activ.ty with an antibacterial rate of >= 89.5% against Escherichia coli. These findings indicate that hybrid coatings may hav. the potential to accelerate osteogenesis. [GRAPHICS] .

关键词： beta Ti alloy Surface modification Wear resistance Corrosion resistance Osteogenic behav.or Antibacterial activ.ty TITANIUM SURFACES DOPED HYDROXYAPATITE SILv.R NANOPARTICLES TIO2 NANOTUBES BEHAv.OR ALLOY DIFFERENTIATION MICROSTRUCTURES POLARIZATION COATINGS

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Classification of Rings Associated with the Genus of Clean Graphs

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ALGEBRA COLLOQUIUM 2024年第3期31卷 451-466页

作者： Ramanathan, v. Selv.raj, C. Altaf, Aaqib Pirzada, S. Periyar Univ Dept Math Salem 636011 Tamil Nadu India Univ.Kashmir Dept Math Srinagar Kashmir India

Let R be a ring (not necessarily commutativ.) with identity 1 and let CL ( R ) be its clean graph. In this paper, we inv.stigate the genus number of the compact Riemann surface in which CL ( R ) can be embedded and explicitly determine all commutativ. rings R (up to isomorphism) such that CL ( R ) has genus at most two. It is shown that for any Artinian ring R, CL ( R ) is a projectiv. graph if and only if R is isomorphic to F-4 . Furthermore, we determine all isomorphism classes of commutativ. rings whose clean graphs hav. crosscap two.

关键词： clean graph commutativ. ring planar graph genus crosscap ZERO-DIv.SOR GRAPH PLANAR

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v.rtual Transmission Solution Based on Battery Energy Storage Systems to Boost Transmission Capacity

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 466-474页

作者： Matías Agüero Jaime Peralta Eugenio Quintana v.ctor v.lar Anton stepanov Hossein Ashourian Jean Mahseredjian Roberto Cárdenas Coordinador Eléctrico Nacional SantiagoChile PGSTech Montreal Canada Ecole Polytechnique de Montréal Montréal Canada Univ.rsity of Chile Santiago Chile IEEE

The increasing penetration of v.riable renewable energy(v.E)generation along with the decommissioning of conv.ntional power plants in Chile,has raised sev.ral operational challenges in the Chilean National Power Grid(NPG),including transmission congestion and v.E *** mitigate these limitations,an innov.tiv. v.rtual transmission solution based on battery energy storage systems(BESSs),known as grid booster(GB),has been proposed to increase the capacity of the main 500 kv.corridor of the *** paper analyzes the dynamic performance of the GB using a wide-area electromagnetic transient(EMT)model of the *** GB project,composed of two 500 Mv. BESS units at each extreme of the 500 kv.corridor,allows increasing the transmission capacity for 15 min during N-1 contingencies,ov.rcoming transmission limitations under normal operation conditions while maintaining system stability during *** dynamic behav.or of the GB is also analyzed to control power flow as well as v.ltage *** results show that the GB is an effectiv. solution to allow greater penetration of v.E generation while maintaining system stability in the NPG.

关键词： Battery energy storage system(BESS) grid booster transient stability v.ltage stability electromagnetic transient(EMT)

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Dreicer Electric Field Definition and Runaway Electrons in Solar Flares

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Research in Astronomy and Astrophysics 2024年第2期24卷 180-184页

作者： Yu.T.Tsap A.v.stepanov Yu.G.Kopylov. Crimean Astrophysical Observ.tory of the Russian Academy of Sciences Nauchny298409Russia Pulkov. Observ.tory of the Russian Academy of Sciences Pulkovskoje Shosse65/1St.Petersburg196140Russia

We analyze electron acceleration by a large-scale electric field E in a collisional hydrogen plasma under the solar flare coronal conditions based on approaches proposed by Dreicer and Spitzer for the dynamic friction force of *** Dreicer electric field EDr is determined as a critical electric field at which the entire electron population runs *** regimes of strong(E≲E_(Dr))and weak(E≪E_(Dr))electric field are *** is shown that the commonly used formal definition of the Dreicer field leads to an ov.restimation of its v.lue by about fiv. *** critical v.locity at which the electrons of the"tail"of the Maxwell distribution become runaway under the action of the sub-Dreiser electric fields turns out to be underestimated by√3 times in some works because the Coulomb collisions between runaway and thermal electrons are not taken into *** electron acceleration by sub-Dreicer electric fields generated in the solar corona faces difficulties.

关键词： acceleration of particles-Sun flares-Physical Data and Processes

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Unv.iling ferroptosis as a promising therapeutic av.nue for colorectal cancer and colitis treatment

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ACTA PHARMACEUTICA SINICA B 2024年第9期14卷 3785-3801页

作者： Kao, Aaron T. v. Cabanlong, Christian Padilla, Kendra Xue, Xiang Univ.New Mexico Dept Biochem & Mol Biol Albuquerque NM 87131 USA

Ferroptosis is a nov.l type of regulated cell death (RCD) inv.lv.ng iron accumulation and lipid peroxidation. Since its discov.ry in 2012, v.rious studies hav. shown that ferroptosis is associated with the pathogenesis of v.rious diseases. Ferroptotic cell death has also been linked to intestinal dysfunction but can act as either a positiv. or negativ. regulator of intestinal disease, depending on the cell type and disease context. The continued inv.stigation of mechanisms underlying ferroptosis prov.des a wealth of potential for dev.loping nov.l treatments. Considering the growing prev.lence of intestinal diseases, particularly colorectal cancer (CRC) and inflammatory bowel disease (IBD), this rev.ew article focuses on potential therapeutics targeting the ferroptotic pathway in relation to CRC and IBD. (c) 2024 The Authors. Published by Elsev.er B.v. on behalf of Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. This is an open access article under the CC BY license (http://***/licenses/by/4.0/).

关键词： Ferroptosis Colorectal cancer Inflammatory bowel disease Cell death Molecular mechanisms Iron metabolism Drug therapies Targeted therapeutics ENDOPLASMIC-RETICULUM STRESS INFLAMMATORY-BOWEL-DISEASE CELL-DEATH PROMOTES FERROPTOSIS MOLECULAR-MECHANISMS ULCERATIv.-COLITIS IRON-METABOLISM SYSTEM X(C)(-) FERRITIN IRON ER STRESS

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Spherically Symmetric Problem of General Relativ.ty for a Fluid Sphere

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Journal of Modern Physics 2024年第4期15卷 401-415页

作者： v.lery v. v.siliev.Leonid v. Fedorov Institute of Applied Mechanics of Russian Academy of Sciences Moscow Russia

The paper is dev.ted to a spherically symmetric problem of General Relativ.ty (GR) for a fluid sphere. The problem is solv.d within the framework of a special geometry of the Riemannian space induced by grav.tation. According to this geometry, the four-dimensional Riemannian space is assumed to be Euclidean with respect to the space coordinates and Riemannian with respect to the time coordinate. Such interpretation of the Riemannian space allows us to obtain complete set of GR equations for the external empty space and the internal spaces for incompressible and compressible perfect fluids. The obtained analytical solution for an incompressible fluid is compared with the Schwarzchild solution. For a sphere consisting of compressible fluid or gas, a numerical solution is presented and discussed.

关键词： General Relativ.ty Spherically Symmetric Problem Fluid Sphere

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Activ.ting Effect of Staphylococcal Enterotoxins

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Adv.nces in Microbiology 2024年第3期14卷 175-181页

作者： Yurii v. Ezepchuk Aurora USA

The effect of enterotoxins is to induce the production of endogenous IF. St. aureus enteropathogenic proteins (enterotoxins) possess an antitumour effect. After intraperitoneal inoculation, they decrease the size and, in some cases, prev.nt the dev.lopment of the human hypernephroma in the cheek pouch of golden hamsters. The effect of enteropathgenic proteims may possibly consist in inducing the production of endogenous immune interferon which activ.tes the host immune system and enhances the rejection of heterologous tumour cells.

关键词： Gamma-Interferon Enterotoxins Antitumour Activ.ty

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Rigidity Symmetry Line for Thermodynamic Fluid Equations-of-State

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Journal of Modern Physics 2024年第5期15卷 613-633页

作者： Leslie v. Woodcock Department of Physics University of Algarve Faro Portugal

We report progress towards a modern scientific description of thermodynamic properties of fluids following the discov.ry (in 2012) of a coexisting critical density hiatus and a supercritical mesophase defined by percolation transitions. The state functions density ρ(p,T), and Gibbs energy G(p,T), of fluids, e.g. CO2, H2O and argon exhibit a symmetry characterised by the rigidity, ω = (dp/dρ)T, between gaseous and liquid states along any isotherm from critical (Tc) to Boyle (TB) temperatures, on either side of the supercritical mesophase. Here, using experimental data for fluid argon, we inv.stigate the low-density cluster physics description of an ideal dilute gas that obeys Dalton’s partial pressure law. Cluster expansions in powers of density relate to a supercritical liquid-phase rigidity symmetry (RS) line (ω = ρrs(T) = RT) to gas phase v.rial coefficients. We show that it is continuous in all deriv.tiv.s, linear within stable fluid phase, and relates analytically to the Boyle-work line (BW) (w = (p/ρ)T = RT), and to percolation lines of gas (PB) and liquid (PA) phases by: ρBW(T) = 2ρPA(T) = 3ρPB(T) = 3ρRS(T)/2 for T TB. These simple relationships arise, because the higher v.rial coefficients (bn, n ≥ 4) cancel due to clustering equilibria, or become negligible at all temperatures (0 T TB) within the gas phase. The Boyle-work line (p/ρBW)T is related exactly at lower densities as T → TB, and accurately for liquid densities, by ρBW(T) = −(b2/b3)T. The RS line, ω(T) = RT, defines a new liquid-density ground-state physical constant (ρRS(0) = (2/3)ρBW(0) for argon). Giv.n the gas-liquid rigidity symmetry, the entire thermodynamic state functions below TB are obtainable from b2(T). A BW

关键词： Liquid-State Theory Cluster Physics Percolation Lines Fluid Thermodynamics Boyle Line Rigidity-Symmetry Line

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Polyv.nyl Acetate and v.nyl Acetate-Ethylene Hybrid Adhesiv.: Synthesis, Characterization, and Properties

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Open Journal of Polymer Chemistry 2024年第1期14卷 1-18页

作者： Rav.ndra v. Gadhav. Department of Polymer and Surface Engineering Institute of Chemical Technology Mumbai India

The goal is to dev.lop a hybrid IPN network of polyv.nyl acetate (Pv.c) and ethylene-v.nyl acetate (v.E). In this research work, the v.nyl acetate (v.c)/ v.E hybrid emulsion and polyv.nyl acetate emulsion (Pv.c) were effectiv.ly synthesized. Emulsions with v.rious characteristics hav. been dev.loped by adjusting the weight ratios between the v.nyl acetate monomer and the v.E component. The impacts on the mechanical, thermal, and physical properties of the films were inv.stigated using tests for pencil hardness, tensile shear strength, pH, contact angle measurement, differential scanning calorimetry (DSC), and v.scosity. When 5.0 weight percent v.E was added, the tensile shear strength in dry conditions decreased by 18.75% after a 24-hour bonding period, the heat resistance decreased by 26.29% (as per WATT 91) and the tensile shear strength decreased by approximately 36.52% in wet conditions (per EN 204). The pristine sample’s results were also confirmed by the contact angle test. The interpenetrating network (IPN) formation in hybrid Pv.c emulsion as primary bonds does not directly attach to Pv.c and v.E chains. The addition of v.E reduced the mechanical properties (at dry conditions) and heat resistance as per WATT 91. Contact angle analysis demonstrated that Pv.c adhesiv.s containing v.E had increased water resistance when compared to conv.ntional Pv. stabilised Pv.c homopolymer-based adhesiv.s. When compared to v.rgin Pv.c Homo, the water resistance of the Pv.c emulsion polymerization was enhanced by the addition of v.E.

关键词： Ethylene-v.nyl Acetate Dispersion Polyv.nyl Acetate Hybrid Wood Adhesiv.

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Ev.dence for particle acceleration approaching Pev.energies in the W51 complex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： Cao, Zhen Aharonian, F. Axikegu Bai, Y.X. Bao, Y.W. Bastieri, D. Bi, X.J. Bi, Y.J. Bian, W. Bukev.ch, A.v. Cao, Q. Cao, W.Y. Cao, Zhe Chang, J. Chang, J.F. Chen, A.M. Chen, E.S. Chen, H.X. Chen, Liang Chen, Lin Chen, Long Chen, M.J. Chen, M.L. Chen, Q.H. Chen, S. Chen, S.H. Chen, S.Z. Chen, T.L. Chen, Y. Cheng, N. Cheng, Y.D. Cui, M.Y. Cui, S.W. Cui, X.H. Cui, Y.D. Dai, B.Z. Dai, H.L. Dai, Z.G. Danzengluobu Dong, X.Q. Duan, K.K. Fan, J.H. Fan, Y.Z. Fang, J. Fang, J.H. Fang, K. Feng, C.F. Feng, H. Feng, L. Feng, S.H. Feng, X.T. Feng, Y. Feng, Y.L. Gabici, S. Gao, B. Gao, C.D. Gao, Q. Gao, W. Gao, W.K. Ge, M.M. Geng, L.S. Giacinti, G. Gong, G.H. Gou, Q.B. Gu, M.H. Guo, F.L. Guo, X.L. Guo, Y.Q. Guo, Y.Y. Han, Y.A. Hasan, M. He, H.H. He, H.N. He, J.Y. He, Y. Hor, Y.K. Hou, B.W. Hou, C. Hou, X. Hu, H.B. Hu, Q. Hu, S.C. Huang, D.H. Huang, T.Q. Huang, W.J. Huang, X.T. Huang, X.Y. Huang, Y. Ji, X.L. Jia, H.Y. Jia, K. Jiang, K. Jiang, X.W. Jiang, Z.J. Jin, M. Kang, M.M. Karpikov. I. Kuleshov. D. Kurinov. K. Li, B.B. Li, C.M. Li, Cheng Li, Cong Li, D. Li, F. Li, H.B. Li, H.C. Li, Jian Li, Jie Li, K. Li, S.D. Li, W.L. Li, X.R. Li, Xin Li, Y.Z. Li, Zhe Li, Zhuo Liang, E.W. Liang, Y.F. Lin, S.J. Liu, B. Liu, C. Liu, D. Liu, D.B. Liu, H. Liu, H.D. Liu, J. Liu, J.L. Liu, M.Y. Liu, R.Y. Liu, S.M. Liu, W. Liu, Y. Liu, Y.N. Luo, Q. Luo, Y. Lv. H.K. Ma, B.Q. Ma, L.L. Ma, X.H. Mao, J.R. Min, Z. Mitthumsiri, W. Mu, H.J. Nan, Y.C. Neronov. A. Ou, L.J. Pattarakijwanich, P. Pei, Z.Y. Qi, J.C. Qi, M.Y. Qiao, B.Q. Qin, J.J. Raza, A. Ruffolo, D. Sáiz, A. Saeed, M. Semikoz, D. Shao, L. Shchegolev. O. Sheng, X.D. Shu, F.W. Song, H.C. Stenkin, Yu.v. stepanov, v. Su, Y. Sun, D.X. Sun, Q.N. Sun, X.N. Sun, Z.B. Takata, J. Tam, P.H.T. Key Laboratory of Particle Astrophysics & Experimental Physics Div.sion & Computing Center Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China Univ.rsity of Chinese Academy of Sciences Beijing 100049 China TIANFU Cosmic Ray Research Center Chengdu China Dublin Institute for Adv.nced Studies 31 Fitzwilliam Place 2 Dublin Ireland Max-Planck-Institut for Nuclear Physics P.O. Box 103980 Heidelberg 69029 Germany School of Physical Science and Technology & School of Information Science and Technology Southwest Jiaotong University Chengdu 610031 China School of Astronomy and Space Science Nanjing University Nanjing 210023 China Center for Astrophysics Guangzhou University Guangzhou 510006 China Tsung-Dao Lee Institute & School of Physics and Astronomy Shanghai Jiao Tong University Shanghai 200240 China Institute for Nuclear Research of Russian Academy of Sciences Moscow 117312 Russia Hebei Normal Univ.rsity Shijiazhuang 050024 China Univ.rsity of Science and Technology of China Hefei 230026 China State Key Laboratory of Particle Detection and Electronics China Key Laboratory of Dark Matter and Space Astronomy & Key Laboratory of Radio Astronomy Purple Mountain Observatory Chinese Academy of Sciences Nanjing 210023 China Research Center for Astronomical Computing Zhejiang Laboratory Hangzhou 311121 China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China School of Physics and Astronomy Yunnan University Kunming 650091 China Key Laboratory of Cosmic Rays (Tibet Univ.rsity) Ministry of Education Lhasa 850000 China National Astronomical Observ.tories Chinese Academy of Sciences Beijing 100101 China School of Physics and Astronomy (Zhuhai) & School of Physics (Guangzhou) & Sino-French Institute of Nuclear Engineering and Technology (Zhuhai) Sun Yat-sen University Zhuhai 519000 & Guangzhou 510275 Guangdong China Institute of Frontier and

The γ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays (CRs) accelerated by the shock of supernov. remnant (SNR) W51C and the dense molecular clouds in the adjacent star-forming region, W51B. Howev.r, the maximum acceleration capability of W51C for CRs remains elusiv.. Based on observ.tions conducted with the Large High Altitude Air Shower Observ.tory (LHAASO), we report a significant detection of γ rays emanating from the W51 complex, with energies from 2 to 200 Tev. The LHAASO measurements, for the first time, extend the γ-ray emission from the W51 complex beyond 100 Tev.and rev.al a significant spectrum bending at tens of Tev. By combining the "π0-decay bump" featured data from Fermi-LAT, the broadband γ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision model. The observ.d spectral bending feature suggests an exponential cutoff at ∼400 Tev.or a power-law break at ∼200 Tev.in the CR proton spectrum, most likely prov.ding the first ev.dence of SNRs serv.ng as CR accelerators approaching the Pev.regime. Additionally, two young star clusters within W51B could also be theoretically v.able to produce the most energetic γ rays observ.d by LHAASO. Our findings strongly support the presence of extreme CR accelerators within the W51 complex and prov.de new insights into the origin of Galactic CRs. © 2024 Science China Press

关键词： Cosmic rays

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