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World Journal of Gastroenterology 2024年第15期30卷 2081-2086页

作者： Michele Nardolillo Fabiola Rescigno Mario Bartiromo Dario Piatto stefano Guarino Pierluigi Marzuillo Emanuele Miraglia del Giudice Anna Di Sessa Department of Woman Child and of General and Specialized SurgeryUniversitàdegli Studi della Campania“Luigi Vanvitelli”Naples 80138Italy

Over recent years,the nomenclature of non-alcoholic fatty liver disease has undergone significant ***,in 2020,an expert consensus panel proposed the term“Metabolic(dysfunction)associated fatty liver disease”(MAFLD)to underscore the close association of fatty liver with metabolic abnormalities,thereby highlighting the cardiometabolic risks(such as metabolic syndrome,type 2 diabetes,insulin resistance,and cardiovascular disease)faced by these patients since *** recently,this term has been further replaced with metabolic associated steatotic liver *** is worth noting that emerging evidence not only supports a close and independent association of MAFLD with chronic kidney disease in adults but also indicates its interplay with metabolic ***,comparable pediatric data remain *** the progressive and chronic nature of both diseases and their prognostic cardiometabolic implications,this editorial aims to provide a pediatric perspective on the intriguing relationship between MAFLD and renal function in childhood.

关键词： Metabolic(dysfunction)associated fatty liver disease Renal Function Children Obesity

Incorporating physiological knowledge into correlative species distribution models minimizes bias introduced by the choice of calibration area

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Marine Life Science & Technology 2024年第2期6卷 349-362页

作者： Zhixin Zhang Jinxin Zhou Jorge García Molinos stefano Mammola Ákos Bede‑Fazekas Xiao Feng Daisuke Kitazawa Jorge Assis Tianlong Qiu Qiang Lin CAS Key Laboratory of Tropical Marine Bio-resources and Ecology South China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Guangdong Provincial Key Laboratory of Applied Marine Biology South China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Marine Biodiversity and Ecological Evolution Research Center South China Sea Institute of OceanologyGuangzhou 510301China Global Ocean and Climate Research Center South China Sea Institute of OceanologyGuangzhou 510301China Institute of Industrial Science The University of Tokyo5-1-5 KashiwanohaKashiwaChiba 277-8574Japan Arctic Research Center Hokkaido UniversitySapporoHokkaido 001-0021Japan Finnish Museum of Natural History University of HelsinkiHelsinkiFinland Molecular Ecology Group(MEG) Water Research Institute(IRSA)National Research Council of Italy(CNR)28922 Verbania PallanzaItaly National Biodiversity Future Center(NBFC) PalermoItaly Institute of Ecology and Botany HUN-REN Centre for Ecological ResearchVácrátótHungary Department of Environmental and Landscape Geography ELTE Eötvös Loránd UniversityBudapestHungary Department of Biology University of North CarolinaChapel HillNC 27599USA Centre of Marine Sciences University of AlgarveCampus de GambelasFaroPortugal CAS Key Laboratory of Experimental Marine Biology Institute of OceanologyChinese Academy of SciencesQingdao 266071China University of Chinese Academy of Sciences Beijing 100049China

Correlative species distribution models(SDMs)are important tools to estimate species’geographic distribution across space and time,but their reliability heavily relies on the availability and quality of occurrence *** can be biased when occurrences do not fully represent the environmental requirement of a *** tested to what extent species’physiological knowledge might influence SDM *** on the Japanese sea cucumber Apostichopus japonicus within the coastal ocean of East Asia,we compiled a comprehensive dataset of occurrence *** then explored the importance of incorporating physiological knowledge into SDMs by calibrating two types of correlative SDMs:a naïve model that solely depends on environmental correlates,and a physiologically informed model that further incorporates physiological information as *** further tested the models’sensitivity to calibration area choices by fitting them with different buffered areas around known *** with naïve models,the physiologically informed models successfully captured the negative influence of high temperature on *** and were less sensitive to the choice of calibration *** naïve models resulted in more optimistic prediction of the changes of potential distributions under climate change(i.e.,larger range expansion and less contraction)than the physiologically informed *** findings highlight benefits from incorporating physiological information into correlative SDMs,namely mitigating the uncertainties associated with the choice of calibration *** these promising features,we encourage future SDM studies to consider species physi-ological information where available.

关键词： Bayesian approach Climate change Habitat suitability Physiological knowledge Species distribution model

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高速动车组一系垂向半主动悬挂研究

力学学报 2024年第8期56卷 2423-2435页

作者：曹洪勇付彬王旭刘彬彬 Di Gialleonardo Egidio Bruni stefano 中车青岛四方机车车辆股份有限公司技术中心山东青岛266111 米兰理工大学机械工程系意大利米兰20156

轻量化是轨道交通车辆发展的重要方向,可降低车辆能耗和运营维护成本.然而车体轻量化改变了车体弹性模态频率,增大了车体结构振动,造成车辆垂向舒适性恶化.提出了一系垂向半主动悬挂策略,即采用可变阻尼减振器替换原有一系垂向减振器,... 详细信息

轻量化是轨道交通车辆发展的重要方向,可降低车辆能耗和运营维护成本.然而车体轻量化改变了车体弹性模态频率,增大了车体结构振动,造成车辆垂向舒适性恶化.提出了一系垂向半主动悬挂策略,即采用可变阻尼减振器替换原有一系垂向减振器,通过对减振器阻尼特性进行实时控制,改善车体刚性和一阶弯曲模态振动.分析了车体刚性和弹性振动与构架振动的耦合关系,在此基础上对一系半主动悬挂的工作原理进行阐述.改进了经典的车辆垂向动力学模型,通过模型计算验证了车体和构架的多种耦合振动关系.对磁流变阻尼减振器的动态特性开展试验测试,建立了该减振器的动力学模型,实现对磁流变阻尼减振器非线性特性的准确预测.以国内某高速列车为原型,建立了完整的车辆动力学模型,并结合磁流变阻尼减振器动力学模型,对一系半主动悬挂的控制策略和应用效果展开研究,得到了两种易于工程应用的控制方法.结果表明一系半主动悬挂对车辆垂向振动,尤其是车体一阶弯曲振动具有显著的控制效果,可改善车辆垂向舒适性指标约30%.

关键词：一系半主动垂向舒适性车体一阶弯曲磁流变阻尼

Reply to “Beyond microbial carbon use efficiency”

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National Science Review 2024年第4期11卷 35-37页

作者： Feng Tao Johannes Lehmann Ying-Ping Wang Lifen Jiang Bernhard Ahrens Kostiantyn Viatkin stefano Manzoni Benjamin Z.Houlton Yuanyuan Huang Xiaomeng Huang Yiqi Luo Department of Ecology and Evolutionary Biology Cornell University Soil and Crop Sciences Section School of Integrative Plant ScienceCornell University CSIRO Environment Max Planck Institute for Biogeochemistry Department of Physical Geography and Bolin Centre for Climate Research Stockholm University Department of Global Development Cornell University Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Department of Earth System Science Ministry of Education Key Laboratory for Earth System Modelling Institute for Global Change Studies Tsinghua University

In their commentary, Xiao et al.[1]cautioned that the conclusions on the critical role of microbial carbon use efficiency (CUE) in global soil organic carbon (SOC) storage in the paper by Tao et al.[2] might be too *** claimed that Tao et al.’s study lacked mechanistic consideration of SOC formation and excluded important data *** et al. brought up important points,which can be largely reconciled with our findings by understanding the differences in expressing processes in empirical studies and in models.

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Prognostic role of platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in patients with non-metastatic and metastatic prostate cancer:A meta-analysis and systematic review

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Asian Journal of Urology 2024年第2期11卷 191-207页

作者： stefano Salciccia Marco Frisenda Giulio Bevilacqua Pietro Viscuso Paolo Casale Ettore De Berardinis Giovanni Battista Di Pierro Susanna Cattarino Gloria Giorgino Davide Rosati Francesco Del Giudice Alessandro Sciarra Gianna Mariotti Alessandro Gentilucci Department of Urology Sapienza Rome UniversityPoliclinico Umberto I00161 RomeItaly Department of Urology Humanitas20089 RozzanoMIItaly

Objective: To analyze data available in the literature regarding a possible prognostic value of the platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) in prostate cancer (PCa) patients stratified in non-metastatic and metastatic ***: A literature search process was performed following the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. In our meta-analysis, the pooled event rate estimated and the pooled hazard ratio were calculated using a random effect ***: Forty-two articles were selected for our analysis. The pooled risk difference for non-organ confined PCa between high and low NLR cases was 0.06 (95% confidence interval [CI]: −0.03-0.15) and between high and low PLR cases increased to 0.30 (95% CI: 0.16-0.43). In non-metastatic PCa cases, the pooled hazard ratio for overall mortality between high and low NLR was 1.33 (95% CI: 0.78-1.88) and between high and low PLR was 1.47 (95% CI: 0.91-2.03), whereas in metastatic PCa cases, between high and low NLR was 1.79 (95% CI: 1.44-2.13) and between high and low PLR was 1.05 (95% CI: 0.87-1.24).Conclusion: The prognostic values of NLR and PLR in terms of PCa characteristics and responses after treatment show a high level of heterogeneity of results among studies. These two ratios can represent the inflammatory and immunity status of the patient related to several conditions. A higher predictive value is related to a high NLR in terms of risk for overall mortality in metastatic PCa cases under systemic treatments.

关键词： Prostatic neoplasm Neutrophil-to-lymphocyte ratio Platelet-to-lymphocyteratio Meta-analysis Radical prostatectomy Metastatic

Past,present,and future perspectives of ultrasound-guided ablation of liver tumors:Where could artificial intelligence lead interventional oncology?

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Artificial Intelligence in Cancer 2024年第1期5卷 1-12页

作者： Paola Tombesi Andrea Cutini Valentina Grasso Francesca Di Vece Ugo Politti Eleonora Capatti Florence Labb stefano Petaccia Sergio Sartori Department of Internal Medicine Section of Interventional UltrasoundSt.Anna HospitalFerrara 44100Italy Esaote S.p.A. Genova 16100Italy

The first ablation procedures for small hepatocellular carcinomas were percutaneous ethanol injection under ultrasound(US)***,radiofrequency ablation was shown to achieve larger coagulation areas than percutaneous ethanol injection and became the most used ablation technique *** the past decade,microwave ablation systems have achieved larger ablation areas than radiofrequency ablation,suggesting that the 3-cm barrier could be broken in the treatment of liver ***,US techniques to guide percutaneous ablation have seen important ***-enhanced US(CEUS)can define and target the tumor better than US and can assess the size of the ablation area after the procedure,which allows immediate retreatment of the residual tumor ***,fusion imaging fuses real-time US images with computed tomography or magnetic resonance imaging with significant improvements in detecting and targeting lesions with low conspicuity on ***,software powered by artificial intelligence has been developed to allow three-dimensional segmentation and reconstruction of the anatomical structures,aiding in procedure planning,assessing ablation completeness,and targeting the residual viable foci with greater precision than ***,this could lead to the ablation of tumors up to 5-7 cm in size.

关键词： Artificial intelligence Fusion imaging Percutaneous thermal ablation Microwave ablation Radiofrequency ablation Ultrasound Contrast-enhanced ultrasound

大陆俯冲界面之上大规模硅富集流体的地球物理学证据

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中国科学：地球科学 2024年第9期54卷 2848-2863页

作者：毛元彤赵亮 Marco G.MALUSÀ stefano SOLARINO Silvia PONDRELLI 孙宝璐 Coralie AUBERT Simone SALIMBENI Elena EVA Stéphane GUILLOT 中国科学院地质与地球物理研究所岩石圈演化与环境演变全国重点实验室北京100029 中国科学院大学地球与行星科学学院北京100049 Department of Earth and Environmental Sciences University of Milano-BicoccaMilan 20126Italy Istituto Nazionale di Geofisica e Vulcanologia Osservatorio Nazionale TerremotiGenova 16145Italy Istituto Nazionale di Geofisica e Vulcanologia Sezione di BolognaBologna 40127Italy UniversitéGrenoble Alpes UniversitéSavoie Mont BlancCNRSIRDUGEISTerreGrenoble 38000France

俯冲带中的流体可能对俯冲过程产生重要影响.然而,关于大陆俯冲期间流体规模及其作用的地球物理约束仍然有限.西阿尔卑斯造山带是全球保存最完好的大陆俯冲带之一,为认识大陆俯冲过程中流体作用的影响提供了重要的参考.本文综合多种地... 详细信息

俯冲带中的流体可能对俯冲过程产生重要影响.然而,关于大陆俯冲期间流体规模及其作用的地球物理约束仍然有限.西阿尔卑斯造山带是全球保存最完好的大陆俯冲带之一,为认识大陆俯冲过程中流体作用的影响提供了重要的参考.本文综合多种地球物理方法分析了西阿尔卑斯造山带地区的V_(P)/V_(S)比值,发现在俯冲区的上盘侧存在高V_(P)/V_(S)(>1.9)带,与部分蛇纹岩化的上覆地幔楔位置一致;而在下盘侧存在异常低的V_(P)/V_(S)(<1.7)带,异常深度浅于30km.本文认为,观测到的低V_(P)/V_(S)比值异常是由地壳内广泛分布的富硅岩脉导致,指示了在俯冲时期大陆俯冲界面之上可能存在的富硅流体流动.本文的结果暗示俯冲时期的流体流动可能降低了俯冲界面的有效应力,从而促进了大陆俯冲.

关键词：西阿尔卑斯造山带地壳精细结构接收函数 V_(P)/V_(S)波速比硅富集

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Time reversal of a discrete system coupled to a continuum based on non-Hermitian flip

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Science Bulletin 2017年第12期62卷 869-874页

作者： stefano Longhi Dipartimento di Fisica Politecnico di Milano and Istituto di Fotonica e Nanotecnologie del Consiglio Nazionale delle RicerchePiazza L.da Vinci 321-20133 MilanoItaly

Time reversal in quantum or classical systems described by an Hermitian Hamiltonian is a physically allowed process, which requires in principle inverting the sign of the Hamiltonian. Here we consider the problem of time reversal of a subsystem of discrete states coupled to an external environment characterized by a continuum of states, into which they generally decay. It is shown that, by flipping the discrete-continuum coupling from an Hermitian to a non-Hermitian interaction, thus resulting in a non unitary dynamics, time reversal of the subsystem of discrete states can be achieved, while the continuum of states is not reversed. Exact time reversal requires frequency degeneracy of the discrete states,or large frequency mismatch among the discrete states as compared to the strength of indirect coupling mediated by the continuum. Interestingly, periodic and frequent switch of the discrete-continuum coupling results in a frozen dynamics of the subsystem of discrete states.

关键词： Non-Hermitian dynamicsTime reversalLoschmidt echo

Reply to "Discussion 1 on 'Introspection on improper seismic retrofit of Basilica Santa Maria di Collemaggio after 2009 Italian earthquake' by ***,*** and *** stefano" by Vincenzo Ciampi

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Earthquake Engineering and Engineering Vibration 2012年第2期11卷 283-288页

作者： Gian Paolo Cimellaro Andrei M.Reinhorn Alessandro De stefano Department of Structural Geotechnical & Building Engineering(DISEG)Politecnico di TorinoCorso Duca degli Abruzzi 2410129 TurinItaly Department of Civil Structural & Environmental EngineeringUniversity at Buffalothe State University of New York135 Ketter HallBuffalo NYUSA

The authors thank the discusser for his interest and careful review of the paper and his valuable comments. They also welcome this discussion,because it gives the authors the opportunity to clarify several points whic... 详细信息

关键词： Introspection on improper seismic retrofit of Basilica Santa Maria di Collemaggio after 2009 Italian earthquake by Vincenzo Ciampi Discussion 1 on Reply to De

Reply to "Discussion 2 on 'Introspection on improper seismic retrofit of Basilica Santa Maria di Collemaggio after 2009 Italian earthquake' by G.P. Cimellaro, A.M. Reinhorn and *** stefano" by Enzo Cartapati

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Earthquake Engineering and Engineering Vibration 2012年第2期11卷 291-292页

作者： Gian Paolo Cimellaro Andrei M. Reinhorn Alessandro De stefano Department of Structural Geotechnical & Building Engineering (DISEG) Politecnico di Torino Corso Duca degli Abruzzi 24 10129 Turin Italy Department of Civil Structural & Environmental Engineering University at Buffalo the State University of New York 135 Ketter Hall Buffalo NY USA

The authors thank the discusser for the additional information,which is provided related to the historical interventions of the church through the centuries. This information was known to the authors,however they deci... 详细信息

关键词： Reply to A.M Reinhorn and A.De stefano Introspection on improper seismic retrofit of Basilica Santa Maria di Collemaggio after 2009 Italian earthquake by G.P Discussion 2 on De