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A novel method of quantifying the coating progress in a three-dimensional prismatic spouted bed

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Particuology 2019年第1期17卷 137-145页

作者： Swantje Pietscha Finn Ole Poppinga stefan Heinrich michael müller michael Schonherr Frank Kleine Jager Hamburg University of Technology Institute of Solids Process Engineering and Particle TechnologyDenickestraβe 1521073 HamburgGermany BASF Se RCP/TT67056 LudwigshafenGermany

An optical method of experimentally quantifying the coating progress in a laboratory prismatic spouted bed is presented. microcrystalline cellulose particles with size dp = 0.57 mm are used as core.material. Waterborne coating suspensions with methylene blue as a dye are used and sprayed via a two-fluid nozzle in bottom-spray configuration. A high-speed camera with a color filter is positioned in front of the observation window of the three-dimensional plant and records the flow pattern in the process chamber with a certain frequency. With increasing surface coverage, the particles become bluer and darker. The change in brightness is detected by digital image analysis. In the implemented algorithm, the spherical particles are detected, cut from the background and normalized regarding their lighting and area. The detection of coated pixels on the single particles allows the calculation of the coating fraction and coating uniformity after a Kalman filter has been applied to reduce noise. It is shown that the.method can be used to dete.mine the time needed to reach the.maximum blue value indicating a complete coating of the particle bed. Besides the.minimum coating duration, information on the spraying performance (e.g., the time point of a possibly occurring blockage of the nozzle) can be obtained from the data. Two exemplary experiments are presented, showing a connection of the slope of the coating fraction and the uniformity of the coating of the particles in the apparatus that results in the recommendation of a slow liquid injection for obtaining consistent coating layers as desired in many applications.

关键词： Spouted bed Particle coating Granulation Digital image analysis

Light tuning CO/H_(2)composition on Ag:Unraveling CO_(2)mass transfer and electron-phonon coupling in plasmon-enhanced electrocatalysis

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Nano Research 2025年第1期18卷 173-185页

作者： Rui Lin Dong Fan Luca mBerger Thomas Possmayer Yu Zhou Jiexin Zhu Xingbao Chen Wen Luo Lars Allmendinger Andreas Tittl Leonardo de Souza menezes Guillaume.maurin Shihe Yang and stefan Amaier Nanoinstitute.munich Faculty of PhysicsLudwig-Maximilians-Universität München80539 MunichGermany Institut Charles Gerhardt montpellier UmR 5253 CNRS eNSCm UniversitéMontpellierPlace E.Bataillon34090 MontpellierFrance Guangdong Provincial Key Lab of Nano-micro material Research School of Advanced MaterialsPeking University Shenzhen Graduate SchoolShenzhen 518055China State Key Laboratory of Advanced Technology for materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Faculty of Chemistry and Pharmacy Ludwig-Maximilians-Universität München81377 MunichGermany Departamento de Física Universidade Federal de Pernambuco50670-901 Recife-PEBrazil School of Physics and Astronomy Monash University Clayton CampusMelbourneVictoria 3800Australia Department of Physics Imperial College LondonSW72AZ LondonUK

Plasmon-enhanced electrocatalysis(PeeC)is an emerging approach to mitigate CO_(2)*** mechanisms behind CO_(2)adsorption and reduction at the catalyst-electrolyte interface in PeeC still need to be further ***,we employ a well-defined Ag nanostructure to elucidate these pivotal *** shining light with wavelengths of 625,525,405 nm on Ag,an adjustable CO/H_(2)ratio from 35 to 1 can be *** reaction pathway changing under plasmonic excitation does not originate from the lowered CO_(2)mass transfer in the vicinity of Ag,as the electrochemical quartz crystal microbalance results unravel that a slightly elevated temperature in bulk electrolyte caused by light irradiation cannot weaken the CO_(2)adsorption at the Ag catalyst-electrolyte *** calculations reveal that optical excitation towards shorter wavelengths leads to a progressive lowered energy barrier for H_(2)formation together with an enhanced energy barrier for^(*)COOH *** the.modynamically suppressed,CO_(2)reduction can still be improved kinetically by optimizing the excitation wavelength and intensity,being accompanied with the enhanced *** absorption spectroscopy results further correlate the higher photocurrent with a prolonged electron-phonon coupling time,verifying that the improvement of CO_(2)reduction kinetics in PeeC can be realized by hot electron harnessing.

关键词： plasmonic catalysis photoelectrochemical CO_(2)reduction CO/H_(2)ratio hot electron generation electronphonon coupling the.mal effect

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Frontiers of environmental Science & engineering 2021年第2期15卷 77-85页

作者： Om Prakash stefan JGreen Pooja Singh Puja Jasrotia Joel e.Kostka earth Ocean and Atmospheric Science Department Florida State UniversityTallahasseeFL 32306USA National Centre for microbial Resource National Centre for Cell ScienceMaharashtraPune-411007India Genome Research Core University of Illinois at ChicagoChicagoIL 60607USA Department of Biological Sciences University of Illinois at ChicagoChicagoIL 60607USA Georgia Institute of Technology Schools of Biology and earth&Atmospheric Sciences AtlantaGA 30332USA Symbiosis School of Biological Sciences Symbiosis International(Deemed University)LavalePune-412115India

This work examines the physiologic basis of stress tolerance in bacterial strains of the genus Rhodanobacter that dominate in the acidic and highly metal contaminated near-source subsurface zone of the Oak Ridge Integrated Field Research Challenge(ORIFRC)*** of *** to levels of different stresses were studied in synthetic groundwater medium and R2A *** strains of ***,strains 2APBS1T and 116-2,tolerate low to circumneutral pH(4–8),high Uranium(1 mmol/L),elevated levels of nitrate(400 mmol/L)and high NaCl(2.5%).A combination of physiologic traits,such as growth at low pH,increased growth in the presence of high organics concentration,and tolerance of high concentrations of nitrate,NaCl and heavy metals is likely responsible for dominance of Rhodanobacter at the ORIFRC ***,extended incubation times and use of low carbon media,better approximating site groundwater conditions,are critical for accurate dete.mination of stress *** study expands knowledge of the ecophysiology of bacteria from the genus Rhodanobacter and identifies methodological approaches necessary for acquiring accurate tolerance data.

关键词： Rhodanobacter Uranium Nitrate metals Stress tolerance

On-target temporal characterization of optical pulses at relativistic intensity

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Light(Science & Applications) 2019年第1期8卷 278-286页

作者： Vyacheslav e.Leshchenko Alexander Kessel Olga Jahn mathias Kruger Andreas münzer Sergei ATrushin Laszlo Veisz Zsuzsanna major stefan Karsch max-Planck-Institut fur Quantenoptik 85748 GarchingGermany Department fur Physik Ludwig-Maximilians-Universitat Munchen85748 GarchingGermany Department of Physics Umea UniversityUmeåSE-90187Sweden Department of Physics The Ohio State UniversityColumbusOH 43210USA GSI He.mholtzzentrum fur Schwerionenforschung GmbH PlanckstraBe 164291 DarmstadtGermany He.mholtz-Institut Jena Frobelstieg 307743 JenaGermany

High-field experiments are very sensitive to the exact value of the peak intensity of an optical pulse due to the nonlinearity of the underlying ***,precise knowledge of the pulse intensity,which is mainly limited by the accuracy of the temporal characterization,is a key prerequisite for the correct interpretation of experimental *** the detection of energy and spatial profile is well established,the unambiguous temporal characterization of intense optical pulses,another important parameter required for intensity evaluation,remains a challenge,especially at relativistic intensities and a few-cycle pulse ***,we report on the progress in the temporal characterization of intense laser pulses and present the relativistic surface second harmonic generation dispersion scan(RSSHG-D-scan)—a new approach allowing direct on-target temporal characterization of high-energy,few-cycle optical pulses at relativistic intensity.

关键词： optical relativistic intensity

experimental investigation on slip conditions during thread rolling with flat dies

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Friction 2024年第1期12卷 136-143页

作者： stefan VOLZ Peter GROCHe Institute for Production engineering and Forming machines Technical University DarmstadtOtto-Berndt Straße 2Darmstadt 64287Germany

The process design of flat die rolling operations can be a tedious and costly process due to the challenges posed by small process *** this work,an effort is made to closely investigate and understand the process limits caused by excessive slippage of the *** measurements are carried out to capture the characteristics of excessive slippage and the influence of the stroke rate and the tribological system on this process *** differences in slippage were observed,depending on the tribological *** systems with polymer based lubricants showed excessive slippage at low stroke rates,systems using oil or no lubricant endured higher stroke rates before process limits were *** optical measurements revealed three.major forms of slippage:successful rolling without slippage,failure due to excessive slippage at process start,and failure due to excessive slippage at around one workpiece rotation.

关键词： rolling incremental forming thread rolling slippage profile rolling

RIG-I immunotherapy overcomes radioresistance in p53-positive.malignant melanoma

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Journal of molecular Cell Biology 2023年第1期15卷 13-26页

作者： Silke Lambing Yu Pan Tan Paraskevi Vasileiadou stefan Holdenrieder Patrick müller Christian Hagen Stephan Garbe Rayk Behrendt martin Schlee Jasper G.van den Boorn eva Bartok marcel Renn Gunther Hartmann Institute of Clinical Chemistry and Clinical Pharmacology University Hospital BonnBonn 53127Germany Institute of Laboratory medicine German Heart CentreMunich 80636Germany Department of Radiation Oncology University Hospital BonnBonn 53127Germany Unit of experimental Immunology Department of Biomedical SciencesInstitute of Tropical MedicineAntwerp 2000Belgium Institute of experimental Haematology and Transfusion medicine University Hospital BonnBonn 53127Germany mildred Scheel School of Oncology BonnUniversity Hospital BonnMedical FacultyBonn 53127Germany

Radiotherapy induces DNA damage,resulting in cell cycle arrest and activation of cell-intrinsic death ***,the radioresistance of some tumour entities such as malignant melanoma limits its clinical *** innate immune sensing receptor retinoic acid-inducible gene I(RIG-I)is ubiquitously expressed and upon activation triggers an immunogenic form of cell death in a variety of tumour cell types including *** date,the potential of RIG-I ligands to overcome radioresistance of tumour cells has not been ***,we demonstrate that RIG-I activation enhanced the extent and immunogenicity of irradiation-induced tumour cell death in human and murine.melanoma cells in vitro and improved survival in the.murine B16 melanoma model in *** analysis pointed to a central role for p53,which was confirmed using p53^(-/-)B16 *** vivo,the additional effect of RIG-I in combination with irradiation on tumour growth was absent in mice carrying p53^(-/-)B16 tumours,while the antitumoural response to RIG-I stimulation alone was *** results identify p53 as a pivotal checkpoint that is triggered by RIG-I resulting in enhanced irradiation-induced tumour cell ***,the combined administration of RIG-I ligands and radiotherapy is a promising approach to treating radioresistant tumours with a functional p53 pathway,such as melanoma.

关键词： RIG-I p53 melanoma immunotherapy irradiation radiotherapy radioresistance

molecular characterization of intergeneric hybrids between malus and Pyrus

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Horticulture Research 2023年第1期10卷 172-182页

作者： Giulia Pasqualetto Luisa Palmieri stefan martens Vincent G.m.Bus David Chagné Claudia Wiedow mickael A.malnoy Susan e.Gardiner Research and Innovation Centre Edmund Mach FoundationSan Michele all’AdigeTN 38010Italy Department of Agricultural FoodEnvironmental and Animal SciencesUniversity of UdineUD 33100Italy The New Zealand Institute for Plant and Food Research Ltd(PFR) Hawke’s Bay Research CentreHavelock North 4442New Zealand PFR Fitzherbert Science CentrePalmerston NorthNew Zealand

Apple.malus)and pear(Pyrus)are economically important fruit crops well known for their unique textures,f lavours,and nutritional *** genera are characterised by a distinct pattern of secondary metabolites,which directly affect not only resistance to certain diseases,but also have significant impacts on the f lavour and nutritional value of the *** identical chromosome numbers,similar genome size,and their recent divergence date,together with DNA markers have shown that apple and pear genomes are highly *** study utilized comparative genomic approaches,including simple sequence repeats,high resolution single nucleotide polymorphism melting analysis,and single nucleotide polymorphism chip analysis to identify genetic differences among hybrids of malus and Pyrus,and F2 *** research has demonstrated and validated that these three.marker types,along with metabolomics analysis are very powerful tools to detect and confirm hybridity of progeny derived from crosses between apple and pear in both cross ***,this work analysed the genus-specific metabolite patterns and the resistance to fire blight(erwinia amylovora)in *** findings of this work will enhance and accelerate the breeding of novel tree fruit crops that benefit producers and consumers,by enabling marker assisted selection of desired traits introgressed between pear and apple.

关键词： crops utilized breeding

Product design based on discrete particle.modeling of a fluidized bed granulator

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Particuology 2014年第1期12卷 13-24页

作者： Lennart Fries Sergiy Antonyuk stefan Heinrich Gerhard Niederreiter stefan Palzer Nestlé Research Center Institute of Solids Process engineering and Particle Technology Hamburg University of Technology

Fluidized bed agglomeration is a process commonly used to construct powdered food or pharmaceuti cal products to improve their instant properties. This works analyzes the influence of a wide range of operating parameters （i.e., fluidization air flow rate, temperature, and liquid injection rate） on growth rate, process stability, and product particle structure. Different granulator configurations （i.e., top spray, Wurster coater, spouted bed） are compared using identical process parameters. The impacts of both pro cess variables and granulator ge.metry on the fluidization regime, the particle and collision dynamics, and the resulting product structure and corresponding properties are studied in detailed simulations using a discrete particle.model （DPm） and labscale agglomeration experiments with amorphous dextrose syrup （De21）. The combination of numerical and experimental results allows to correlate the kinetics of micro scale particle interactions and the final product properties （i.e., agglomerate structure and strength）. In conclusion, detailed DPm simulations are proven as a valuable tool for knowledgebased product design.

关键词： FluidizationAgglomerationDiscrete element methodFood powderCollision dynamics

Transfer learning applications for autoencoder-based anomaly detection in wind turbines

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energy and AI 2024年第3期17卷 1-10页

作者： Cyriana m.A.Roelofs Christian Gück stefan Faulstich Fraunhofer Iee Joseph-Beuys-Straße 834117 KasselGermany

Anomaly detection in wind turbines typically involves using normal behaviour models to detect faults *** behaviour models are often implemented through the use of neural networks,of which autoencoders are particularly popular in this ***,training autoencoder models for each turbine is time-consuming and resource ***,transfer learning becomes essential for wind turbines with limited data or applications with limited computational *** study examines how cross-turbine transfer learning can be applied to autoencoder-based anomaly ***,autoencoders are combined with constant thresholds for the reconstruction error to dete.mine if input data contains an *** models are initially trained on one year’s worth of data from one or more source wind *** are then fine-tuned using small amounts of data from the target wind *** methods for fine-tuning are investigated:adjusting the entire autoencoder,only the decoder,or only the threshold of the *** performance of the transfer learning models is compared to baseline.models that were trained on one year’s worth of data from the target wind *** results of the tests conducted in this study indicate that models trained on data of multiple wind turbines do not improve the anomaly detection capability compared to models trained on data of one source wind *** addition,modifying the.model’s threshold can lead to comparable or even superior performance compared to the baseline,whereas fine-tuning the decoder or autoencoder further enhances the.models’performance.

关键词： Condition monitoring Transfer learning Autoencoder Anomaly detecti on Wind turbines Fault detection