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Prehospital response to respiratory distress by the public ambulance system in a Ukrainian city

World Journal of Emergency Medicine 2019年第1期10卷 42-45页

作者： Colin A.Meghoo stanislav Gaievskyi Oleksandr Linchevskyy Bindhu Oommen Kateryna Stetsenko Research Department Patriot Defence School of Public Health Kyiv-Mohyla Academy Clinical Hospital #17 Hunt Regional Medical Center Center of Emergency Medical Care and Disaster Medicine

BACKGROUND: The capability of the public ambulance system in Ukraine to address urgent medical complaints in a prehospital environment is unknown. Evaluation using reliable sources of patient data is needed to provide insight into current treatments and outcomes. METHODS: We obtained access to de-identifi ed computer records from the emergency medical services(EMS) dispatch center in Poltava, a medium-sized city in central Ukraine. Covering a fi vemonth period, we retrieved data for urgent calls with a patient complaint of respiratory distress. We evaluated ambulance response and treatment times, field diagnoses, and patient disposition, and analyzed factors related to fatal outcomes. RESULTS: Over the f ive-month period of the study, 2,029 urgent calls for respiratory distress were made to the Poltava EMS dispatch center. A physician-led ambulance typically responded within 10 minutes. Seventy-seven percent of patients were treated and released, twenty percent were taken to hospital, and three percent died in the prehospital phase. On univariate analysis, age over 60 and altered mental status at the time of the call were strongly associated with a fatal outcome. CONCLUSION: The EMS dispatch center in a medium-sized city in Ukraine has adequate organizational infrastructure to ensure that a physician-led public ambulance responds rapidly to complaints of respiratory distress. That EMS system was able to manage most patients without requiring hospital admission. However, a prehospital fatality rate of three percent suggests that further research is warranted to determine training, equipment, or procedural needs of the public ambulance system to manage urgent medical conditions.

关键词： Emergency Medical Services Dyspnea Ukraine

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Gastrointestinal microbiome and Helicobacter pylori:Eradicate,leave it as it is,or take a personalized benefit-risk approach?

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World Journal of Gastroenterology 2022年第7期28卷 766-774页

作者： stanislav Sitkin Leonid Lazebnik Elena Avalueva Svetlana Kononova Timur Vakhitov Department of Internal Diseases Gastroenterology and DieteticsNorth-Western State Medical University Named After I.I.MechnikovSt.Petersburg 191015Russia Non-Infectious Disease Metabolomics Group Institute of Experimental MedicineSt.Petersburg 197376Russia Epigenetics and Metagenomics Group Institute of Perinatology and PediatricsAlmazov National Medical Research CentreSt.Petersburg 197341Russia Department of Outpatient Therapy A.I.Yevdokimov Moscow State University of Medicine and DentistryMoscow 127473Russia Institute of Protein Research Russian Academy of SciencesPushchinoMoscow region 142290Russia

Helicobacter pylori(***)is generally regarded as a human pathogen and a class 1 carcinogen,etiologically related to gastric and duodenal ulcers,gastric cancer,and mucosa-associated lymphoid tissue ***,*** can also be regarded as a commensal *** other pathogenic/opportunistic bacteria,*** colonization in infancy is facilitated by T helper type 2 immunity and leads to the development of immune *** gastric mucin glycans,which are an important part of the innate and adaptive immune system,mediate the adhesion of *** to the surface of the gastric epithelium,contributing to successful *** may have beneficial effects on the host by regulating gastrointestinal(GI)microbiota and protecting against some allergic and autoimmune disorders and inflammatory bowel *** potential protective role against inflammatory bowel disease may be related to both modulation of the gut microbiota and the immunomodulatory properties of *** inverse association between *** and some potentially proinflammatory and/or procarcinogenic bacteria may suggest it regulates the GI *** of *** can cause various adverse effects and alter the GI microbiota,leading to short-term or long-term ***,studies have shown that gastric Actinobacteria decrease after *** eradication,Proteobacteria increase during short-term follow-up and then return to baseline levels,and Enterobacteriaceae and Enterococcus increase in the short-term and interim *** gastric mucosal bacteria(Actinomyces,Granulicatella,Parvimonas,Peptostreptococcus,Prevotella,Rothia,Streptococcus,Rhodococcus,and Lactobacillus)may contribute to precancerous gastric lesions and cancer itself after *** *** eradication can also lead to dysbiosis of the gut microbiota,with increased Proteobacteria and decreased Bacteroidetes and *** increase in gut Proteobacteria may c

关键词： Helicobacter pylori Eradication Gastrointestinal microbiota Dysbiosis Fucosylated glycan Inflammatory bowel disease

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Parametric wind design

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Frontiers of Architectural Research 2018年第3期7卷 383-394页

作者： Lenka Kormarrikova Henri Achten Milos Kopriva stanislav Kmet Faculty of Civil Engineering Institute of Architectural Engineering Technical University of Kosice Vysokoskolska 4 042 00 Slovakia Faculty of Architecture Czech Technical University in Prague Thakurova 9 160 00 Czech Republic Faculty of Civil Engineering Czech Technical University in Prague Thakurova 7 160 00 Czech Republic Faculty of Civil Engineering Institute of Structural Engineering Technical University of Kosice Vysokoskolska 4 042 00 Slovakia

Although gradual, the changes in the weather patterns are also noticeable and impactful to architectural design. If the local microclimate is taken into account early in the conceptual stage of design, the longevity of the ultimate structure can be greatly enhanced, despite challenging environmental factors. Parametric designing enables to discover the optimal architectural shape based on specific weather data. The paper intends to investigate how this design approach, coupled with Computational Fluid Dynamics simulations, can be used to create a wind-induced architecture. Both the benefits and the limitations of this approach are explored in detail. The interaction between an architectural shape and wind flow is tested in a study called ‘FlowBrane’. The process of （1） designing a parametrically changeable geometry, （2） testing its behavior in the wind, and （3） evaluating the results allows looping back to the initial geometric design, continuing to improve the design and ultimately the performance of the architecture in the specific wind conditions of the chosen site. However, the need to test multiple geometries separately and to adjust the wind simulation for each test （and for every wind direction） remains a disadvantage that should be addressed in further research.

关键词： Parametric architecture Computational Fluid Dynamics Wind Performance Early design stage

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蝗虫脚掌微结构及其接触的有限元分析

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上海交通大学学报 2003年第1期37卷 66-69页

作者：戴振东 stanislav Gorb 南京航空航天大学机电学院设计工程系南京210016 BiologicalMicrotribologyGroup Max-Planck-InstituteforDevelopmentalBiology

用电子显微镜研究了蝗虫足掌的微结构 ,用非线性有限元方法分析足掌接触过程的变形规律、接触刚度及接触面积、气囊的作用和足掌的应力应变规律 .结果表明 ,蝗虫足掌以软性外表皮包含血浆 (液体 )的结构形式 ,有利于降低接触刚度、增加... 详细信息

用电子显微镜研究了蝗虫足掌的微结构 ,用非线性有限元方法分析足掌接触过程的变形规律、接触刚度及接触面积、气囊的作用和足掌的应力应变规律 .结果表明 ,蝗虫足掌以软性外表皮包含血浆 (液体 )的结构形式 ,有利于降低接触刚度、增加接触面积 ,并使爪垫在接触过程便产生有利于稳定附着的摩擦力 .软性外表皮内的树丛状杆组织结构会提高足掌在各种表面上的适应性。

关键词：蝗虫脚掌微结构接触过程接触面积接触刚度变形规律非线性有限元分析

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Boron isotopic variations in tourmaline from metacarbonates and associated calc-silicate rocks from the Bohemian Massif: Constraints on boron recycling in the Variscan orogen

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Geoscience Frontiers 2021年第1期12卷 219-230页

作者： Lukas Krmcek Milan Novak Robert B.Trumbull Jan Cempirek stanislav Houzar Department of Geological Sciences Faculty of ScienceMasaryk UniversityKotlarska 2CZ-61137BrnoCzech Republic Institute of Geology of the Czech Academy of Sciences Rozvojova 269CZ-16502Prague 6Czech Republic Brno University of Technology Faculty of Civil EngineeringAdMaS CentreVeve■rí95CZ-60200BrnoCzech Republic GFZ German Research Centre for Geosciences TelegrafenbergD-14473PotsdamGermany Department of Mineralogy and Petrography Moravian MuseumZelnyTrh 6CZ-67401BrnoCzech Republic

Various metacarbonate and associated calc-silicate rocks form minor but genetically significant components of the lithological units in the Bohemian Massif of the Variscan orogen in Central *** rocks vary in terms of their lithostratigraphy,chemical composition and mineral assemblage(dolomite/calcite ratio,silicate abundance).Tourmaline is present in five paragenetic settings within the metacarbonate and calc-silicate ***Ⅰcomprises individual,euhedral,prismatic grains and grain aggregates in a carbonate-dominant(calcite±dolomite)matrix poor in ***Ⅱis characterized by euhedral to subhedral grains and coarse-to fine-grained aggregates in silicate-rich layers/nests within metacarbonate bodies whereas typeⅢoccurs as prismatic grains and aggregates at the contact zones between carbonate and associated silicate host ***Ⅳis in veins crosscutting metacarbonate bodies,and typeⅣtourmaline occurs at the exocontacts of elbaite-subtype granitic *** from the different settings shows distinctive compositional *** for typeⅠare Mg-rich compositions,with fluor-uvite>dravite>>*** from typeⅡsilicate-rich layers/nests are highly variable,corresponding to oxy-schorl,magnesio-foitite,Al-rich dravite and *** for typeⅢtourmalines are Ca,Ti-bearing oxy-dravite *** typeⅣveins feature dravite and fluor-uvite tourmaline compositions whereas typeⅤtourmaline is Li,F-rich *** is the only Bbearing phase in paragenetic typesⅠ-Ⅳ,where it is characterised by two principal ranges of B-isotope composition(δ^11B=-13‰to-9‰and-18‰to-14‰).These ranges correspond to regionally different units of the Moldanubian ***,the Svratka Unit(Moldanubian Zone s.l.)contains only isotopically lighter tourmaline(δ^11B=-18‰to-14‰),whereas metacarbonates in the Poli?ka unit(Teplá-Barrandian Zone)and Olesnice unit(Moravicum of the Moravo-Silesian Zone)has exclusively isotopically heav

关键词： Boron isotopes Tourmaline Metacarbonates Moldanubicum Variscan orogeny

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Color-coded perfluorocarbon nanodroplets for multiplexed ultrasound and photoacoustic imaging

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Nano Research 2019年第4期12卷 741-747页

作者： Daniela Y. Santiesteban Kristina A. Hallam Steven K. Yarmoska stanislav Y. Emelianov Wallace H. Coulter Department of Biomedical Engineering Georgia Institute of Technology and Emory University Atlanta GA 30332 USA School of Electrical & Computer Engineering Georgia Institute of Technology Atlanta GA 30332 USA

Laser-activated perfluorocarb on n anodroplets are an emerging class of phase-cha nge, dual-c ontrast age nts that can be utilized in ultraso und and photoacoustic imaging. Through the ability to differe ntiate subpopulations of nano droplets via laser activatio n at differe nt wavelengths of n ear-infrared light, optically-triggered color-coded perfluorocarb on nano droplets prese nt themselves as an attractive tool for multiplexed ultrasound and photoacoustic imaging. In particular, laser-activated droplets can be used to provide quantitative spatiotemporal information regarding distinct biological targets, allowing for their potential use in a wide range of diagnostic and therapeutic applications. In the work prese nted, laser-activated color-coded perfluorocarb on nan odroplets are syn thesized to selectively resp ond to laser irradiati on at corresp on ding wavele ngths. The dyn amic ultraso und and photoacoustic signals produced by laser-activated perfluorocarbon nano droplets are evaluated in situ prior to implementation in a murine model. In vivo, these particles are used to distinguish unique particle trafficking mechanisms and are show n to provide ultraso und and photoacoustic contrast for up to 72 hours within lymphatics. Overall, the con ducted studies show that laser-activated color-coded perfluorocarbo n nano droplets are a promising agent for multiplexed ultraso und and photoacoustic imaging.

关键词： multiplexed imaging perfluorocarbon nanodroplets photoacoustic imaging ultrasound imaging molecular targets

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The Role of Vanes in the Damping of Bird Feathers

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Journal of Bionic Engineering 2023年第4期20卷 1646-1655页

作者： Kai Deng Hamed Rajabi Alexander Kovalev Clemens F.Schaber Zhendong Dai stanislav N.Gorb Functional Morphology and Biomechanics Institute of ZoologyKiel University24098KielGermany School of Engineering London South Bank UniversityLondonSE10AAUK Institute of Bioinspired Structure and Surface Engineering Nanjing University of Aeronautics and AstronauticsNanjing210026People’s Republic of China

Bird feathers sustain bending and vibrations during *** unwanted vibrations could potentially cause noise and flight *** could alter the system response,resulting in improving quiet flight,stability,and *** of feathers are known to be indispensable for supporting the aerodynamic function of the *** relationship between the hierarchical structures of vanes and the mechanical properties of the feather has been previously ***,still little is known about their relationship with feathers’damping ***,the role of vanes in feathers’damping properties was *** vibrations of the feathers with vanes and the bare shaft without vanes after step deflections in the plane of the vanes and perpendicular to it were measured using high-speed video *** presence of several main natural vibration modes was observed in the feathers with *** trimming vanes,more vibration modes were observed,the fundamental frequencies increased by 51-70%,and the damping ratio decreased by 38-60%.Therefore,we suggest that vanes largely increase feather damping *** mechanisms based on the morphology of feather vanes are *** aerodynamic damping is connected with the planar vane surface,the structural damping is related to the interlocking between barbules and barbs,and the material damping is caused by the foamy medulla inside barbs.

关键词： Bird Feather Vibrations Damping Bionic

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Environmental Changes and Human Impacts on Landscapes near Medieval Steklyanukha-2 Fortress in Russia from Early Iron Age to Modern Times

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Chinese Geographical Science 2023年第1期33卷 69-84页

作者： RAZJIGAEVA Nadezhda GANZEY Larisa KORNYUSHENKO Tatiana GREBENNIKOVA Tatiana KUDRYAVTSEVA Ekaterina PISKAREVA Yana PROKOPETS stanislav Pacific Geographical Institute Far Eastern Branch of the Russian Academy of SciencesVladivostok 690041Russia Institute of History Archaeologyand Ethnography of the Peoples of the Far EastFar Eastern Branch of the Russian Academy of SciencesVladivostok 690091Russia

The development of landscapes in one of the most populated river basins of the southern Russian Far East was studied using pollen and diatom data. The study sites were a multi-layered mountain fortress, Steklyanukha-2, and an Upper Holocene high floodplain sequence of the Steklyanukha River. Buried soil from the fluvial section acts as an environmental archive of the time in which people from the Yankovskaya archeological cultures settled in the river basin. The soil was formed under conditions of decreasing water supply in the valley and prolonged droughts. Findings of pollen Fagopyrum and Urtica signal economic activity in the Early Iron *** lake sediments accumulated from 1.6 to 0.5 kyr, when the valley was actively developed during the Middle Ages. There are signals of the development of secondary birch and oak forests. In the cultural layer of the fortress and lake sediments formed in the Middle Ages, Ambrosia and Xanthium pollens were found and are reliable evidence of agricultural activity in the valley. The pollens of plants typically seen in human-disturbed areas were also found. Indirect evidence of human activity includes non-pollen *** study of diatoms in a depression near a rampart confirmed the archaeologists' assumption that it was used as a water reserve. Pollen spectra from surface soils reflect agricultural activity in the river basin since the second half of the 19th century. The largest amount of pollen of alien and synanthropic plants and weeds, as well as spores of pathogenic fungi and fire indicators, were found here.

关键词： ancient agriculture mountain fortress humidity changes pollen diatoms

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粗糙度对4种聚氨酯弹性体粘着性能的影响

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摩擦学学报 2003年第3期23卷 245-249页

作者：戴振东惠春 stanislav Gorb 南京航空航天大学机电学院江苏南京210016 上海交通大学纳米科学技术研究院上海200030 Biological Micro-tribology Group Max-Planck-Institute for Development Biology

采用生物摩擦磨损试验台测定了4种聚氨酯的弹性模量,研究了表面粗糙度和法向力对粘着力的影响.结果表明:4种聚氨酯的弹性模量在55～1206kPa之间,粘着力由高到低的排序同其弹性模量排序相反,弹性模量较低的试样的饱和粘着力达到15kPa,且... 详细信息

采用生物摩擦磨损试验台测定了4种聚氨酯的弹性模量,研究了表面粗糙度和法向力对粘着力的影响.结果表明:4种聚氨酯的弹性模量在55～1206kPa之间,粘着力由高到低的排序同其弹性模量排序相反,弹性模量较低的试样的饱和粘着力达到15kPa,且表面粗糙度对粘着力的影响不明显;弹性模量较大的试样的粘着力仅为1.5kPa,随弹性模量增加,表面粗糙度的影响增大;试样之间的接触形式同粘着力密切关系,相当于单个凸峰接触的蓝宝石球对聚氨酯试样的粘着力不受法向力的影响,而在平面接触情况下粘着力先随法向力增加而增大,当法向力超过一定(10～15kPa)值后,粘着力增加趋缓并达到饱和值.

关键词：聚氨酯弹性体粘着力粗糙度粘着行为

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Fe-Si particles on the surface of blast furnace coke

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International Journal of Minerals,Metallurgy and Materials 2015年第7期22卷 697-703页

作者： stanislav S.Gornostayev Eetu-Pekka Heikkinen Jyrki J.Heino Timo M.J.Fabritius Process Metallurgy Group University of Oulu

This study investigates the surface of unpolished samples of blast furnace （BF） coke drilled from the tuyere zone, which hosts Fe-Si particles （mostly Fe3Si） that vary in size, shape, depth of submersion （penetration） into the coke matrix, and contact features with the surface. Based on the shape of the particles and the extent of their contact with the coke matrix, they have been grouped into three major types：（I） sphere-like droplets with limited contact area, （II） semi-spheres with a larger contact area, and （III） irregular segregations with a spherical surface, which exhibit the largest contact area among the three types of particles. Considering the ratio between the height （h） of the particles and half of their length at the surface level （/） along the cross-section, these three types can be characterized as follows：（I） h 〉/, （II） h ~/, and （1II） h 〈/. All the three types of particles can be found near each other. The shape and the extent of the contact depend on the de- gree of penetration of the material into the matrix, which is a function of the composition of the particles. Type （I） particles were initially saturated with Si at an earlier stage and, for that reason, they can react less with carbon in the coke matrix than type （II） and （III）, thereby moving faster through the coke cone. Thermodynamic calculations have shown that the temperature interval of 1250-1300~C can be consid- ered the starting point for Si entering into molten iron under quartz-dominated coke ash. Accordingly, the initial pick-up of Si by molten iron can be assumed to be mineral-related. In terms of BF practice, better conditions for sliding Fe-Si droplets through the coke cone are available when they come into contact with free SiO2 concentrated into small grains, and when the SiO2/∑MexOy mass ratio in the coke ash is high.

关键词： blast furnace practice metallurgical coke molten iron iron silicide

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