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Importance of the gut microbiota in the gut-liver axis in normal and liver disease

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World Journal of Hepatology 2024年第6期16卷 878-882页

作者： stanislav Kotlyarov Department of Nursing Ryazan State Medical UniversityRyazan 390026Russia

The gut microbiota is of growing interest to clinicians and researchers.This is because there is a growing understanding that the gut microbiota performs many different functions,including involvement in metabolic and immune processes that are systemic in nature.The liver,with its important role in detoxifying and metabolizing products from the gut,is at the forefront of interactions with the gut microbiota.Many details of these interactions are not yet known to clinicians and researchers,but there is growing evidence that normal gut microbiota function is important for liver health.At the same time,factors affecting the gut microbiota,including nutrition or medications,may also have an effect through the gut-liver axis.

关键词： Gut microbiota Liver Gut-liver axis Immunity Non-alcoholic fatty liver disease

大豆蛋白-黄芩素的结合机制及蛋白构象和功能变化

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食品科学 2023年第4期44卷 91-98页

作者：闫馨月贾亦佳孙诗艳张东蒙耿梦洁杨晋杰 stanislav sukhikh Olga BABICH 齐宝坤李杨东北农业大学食品学院黑龙江哈尔滨150030 康德波罗的海联邦大学生命系统学院俄罗斯加里宁格勒236016 国家大豆工程技术研究中心黑龙江哈尔滨150050

探索大豆蛋白组分中β-伴大豆蛋白(7S)/大豆蛋白(11S)与黄芩素的结合机制,考察复合物构象及功能特性的变化。傅里叶变换红外光谱表明黄芩素诱导蛋白的β-折叠转化为α-螺旋和无规卷曲。内源荧光光谱证实了黄芩素的加入使7S、11S结构变... 详细信息

探索大豆蛋白组分中β-伴大豆蛋白(7S)/大豆蛋白(11S)与黄芩素的结合机制,考察复合物构象及功能特性的变化。傅里叶变换红外光谱表明黄芩素诱导蛋白的β-折叠转化为α-螺旋和无规卷曲。内源荧光光谱证实了黄芩素的加入使7S、11S结构变得更紧密。黄芩素与蛋白的反应自发进行,并通过静态方式猝灭蛋白荧光。7S、11S蛋白分别通过氢键和疏水相互作用与黄芩素结合。分子对接结果表明,黄芩素对11S的亲和力高于7S。扫描电子显微镜显示了7S、11S与复合物的微观结构差异。此外,与黄芩素结合后,7S、11S的表面疏水性下降,热稳定性及其他功能特性提升。

关键词：伴大豆蛋白(7S) 大豆蛋白(11S) 黄芩素结合机制构象变化功能特性

Foam rolling and stretching do not provide superior acute flexibility and stiffness improvements compared to any other warm-up intervention: A systematic review with meta-analysis

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Journal of Sport and Health Science 2024年第4期13卷 509-520页

作者： Konstantin Warneke Gerit Plöschberger Lars H.Lohmann Eric Lichtenstein Daniel Jochum stanislav D.Siegel Astrid Zech David G.Behm Institute of Sport Science University of KlagenfurtKlagenfurt am Wörthersee 9020Austria Department of Human Motion Science and Exercise Physiology Friedrich Schiller UniversityJena 07749Germany Department Sport Exercise and HealthUniversity of BaselBasel 4052Switzerland Department of Health Sciences and Technology ETH ZurichZurich 8092Switzerland School of Human Kinetics and Recreation Memorial University of NewfoundlandSt.JohnsNL A1C 5S7Canada

Background:Acute improvement in range of motion(ROM)is a widely reported effect of stretching and foam rolling,which is commonly explained by changes in pain threshold and/or musculotendinous stiffness.Interestingly,these effects were also reported in response to various other active and passive interventions that induce responses such as enhanced muscle temperature.Therefore,we hypothesized that acute ROM enhancements could be induced by a wide variety of interventions other than stretching or foam rolling that promote an increase in muscle temperature.Methods:After a systematic search in PubMed,Web of Science,and SPORTDiscus databases,38 studies comparing the effects of stretching and foam rolling with several other interventions on ROM and passive properties were included.These studies had 1134 participants in total,and the data analysis resulted in 140 effect sizes(ESs).ES calculations were performed using robust variance estimation model with R-package.Results:Study quality of the included studies was classified as fair(PEDro score=4.58)with low to moderate certainty of evidence.Results showed no significant differences in ROM(ES=0.01,p=0.88),stiffness(ES=0.09,p=0.67),or passive peak torque(ES=-0.30,p=0.14)between stretching or foam rolling and the other identified activities.Funnel plots revealed no publication bias.Conclusion:Based on current literature,our results challenge the established view on stretching and foam rolling as a recommended component of warm-up programs.The lack of significant difference between interventions suggests there is no need to emphasize stretching or foam rolling to induce acute ROM,passive peak torque increases,or stiffness reductions.

关键词： Range of motion Passive properties Muscletendon unit Muscle tissue

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超声辅助花生毛油水化脱胶工艺

食品研究与开发 2024年第12期45卷 66-75页

作者：尚柏余陈乐冯旭梅耿梦洁 sukhikh stanislav 滕飞李杨东北农业大学食品学院黑龙江哈尔滨150030 康德波罗的海联邦大学生命系统学院俄罗斯加里宁格勒236016 黑龙江谱尼测试科技有限公司黑龙江哈尔滨150028

为解决花生毛油水化脱胶率低的问题,该文采用超声辅助水化脱胶的方法对花生毛油进行脱胶处理。通过单因素试验考察加水量、水化温度、超声时间和超声功率对花生毛油脱胶效果的影响。在单因素试验的基础上进行响应面优化,并通过差示扫描... 详细信息

为解决花生毛油水化脱胶率低的问题,该文采用超声辅助水化脱胶的方法对花生毛油进行脱胶处理。通过单因素试验考察加水量、水化温度、超声时间和超声功率对花生毛油脱胶效果的影响。在单因素试验的基础上进行响应面优化,并通过差示扫描量热、气相色谱-质谱联用、顶空-固相微萃取-气相色谱-质谱对花生毛油和脱胶油的热稳定性、脂肪酸组成和挥发性风味物质等进行差异性分析。结果表明,在加水量9%、水化温度75℃、超声时间15min、超声功率65W的条件下,花生脱胶油的磷含量降至最低,为35.18mg/kg,脱胶率达到最高,为89.78%。与水化脱胶相比,脱胶率提高27.43%,酸价、碘值以及过氧化值显著降低(P<0.05),获得的花生脱胶油颜色更加清澈透亮。超声辅助水化脱胶对花生毛油的热稳定影响较小;油脂中的饱和脂肪酸含量下降,油脂品质提升;醛类、吡嗪类和烃类等挥发性风味物质的含量降低,使得甜味和烘烤味等风味特征减弱。

关键词：花生毛油脱胶超声波工艺优化成分鉴定

Thermo-and pH-sensitive Polymer with Pendant Spacer-linked Imidazole Cycles

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Chinese Journal of Polymer Science 2024年第4期42卷 437-445页

作者： Natalya V.Zakharova stanislav N.Zelinskiy Mariya S.Strelova Elena N.Danilovtseva Vadim V.Annenkov Institute of Macromolecular Compounds of the Russian Academy of Sciences Saint Petersburg199004Russia Limnological Institute of Siberian Branch of the Russian Academy of Sciences Irkutsk664033Russia

By the reaction of poly(acryloyl chloride) with N-(3-aminopropyl)imidazole, poly(N-(3-(1H-imidazol-1-yl)propyl)acrylamide) was synthesized. The new polymer contains an imidazole ring removed from the main chain by a spacer of five bonds. The structure and purity, molecular weight, hydrodynamic and thermosensitive properties of the obtained sample were studied by1H-and13C-NMR, FTIR spectroscopy, acid-base titration, light scattering, turbidimetry and viscometry. The observed ability of the imidazole-containing polymer to form and destroy associates in water-salt solutions at pH 6.6-7.4 and temperatures of 29-48℃ indicates that these are promising candidates for designing complex biomedical systems. The new polymer is able to form complexes with oligo-DNA more actively than poly(1-vinylimidazole), which is of interest for gene delivery applications. The polymer cross-linked with epichlorohydrin gives micro-relief coatings on the plastic surface, and the modified surface is able to attach negatively charged objects. This thermo-and pH-sensitive polymer modification can be applied to create finely controlled surfaces for cell culturing.

关键词： Imidazole-containing polymer Thermolability pH-sensitivity The modified surface DNA immobilization

Current and further trajectories in designing functional materials for solid oxide electrochemical cells:A review of other reviews

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Journal of Energy Chemistry 2024年第7期94卷 302-331页

作者： stanislav Baratov Elena Filonova Anastasiya Ivanova Muhammad Bilal Hanif Muneeb Irshad Muhammad Zubair Khan Martin Motola Sajid Rauf Dmitry Medvedev Hydrogen Energy Laboratory Ural Federal University620002 EkaterinburgRussia Institute of Natural Sciences and Mathematics Ural Federal University620002 EkaterinburgRussia Department of Inorganic Chemistry Faculty of Natural SciencesComenius University BratislavaIlkovicova 6Mlynska Dolina84215 BratislavaSlovakia State Key Laboratory for Mechanical Behavior of Materials School of Materials Science and EngineeringXi'an Jiaotong UniversityXi'an 710049ShaanxiChina Department of Physics University of Engineering and TechnologyLahore 54890Pakistan Pak-Austria Fachochschule:Institute of Applied Sciences and Technology Mang Haripur 22621Khyber PakhtunkhwaPakistan College of Mechatronics and Control Engineering Shenzhen UniversityShenzhen 518000GuangdongChina Laboratory of Electrochemical Devices Based on Solid Oxide Proton Electrolytes Institute of High Temperature Electrochemistry620066 EkaterinburgRussia

Complex oxides are an important class of materials with enormous potential for electrochemical appli-cations.Depending on their composition and structure,such complex oxides can exhibit either a single conductivity(oxygen-ionic or protonic,or n-type,or p-type electronic)or a combination thereof gener-ating distinct dual-conducting or even triple-conducting materials.These properties enable their use as diverse functional materials for solid oxide fuel cells,solid oxide electrolysis cells,permeable membranes,and gas sensors.The literature review shows that the field of solid oxide materials and related electro-chemical cells has a significant level of research engagement,with over 8,000 publications published since 2020.The manual analysis of such a large volume of material is challenging.However,by examining the review articles,it is possible to identify key patterns,recent achievements,prospects,and remaining obstacles.To perform such an analysis,the present article provides,for the first time,a comprehensive summary of previous review publications that have been published since 2020,with a special focus on solid oxide materials and electrochemical systems.Thus,this study provides an important reference for researchers specializing in the fields of solid state ionics,high-temperature electrochemistry,and energyconversiontechnologies.

关键词： SOFCs SOECs PCFCS Electrochemistry Energy conversion Hydrogen energy,Carbon neutrality

Large-scale error-tolerant programmable interferometer fabricated by femtosecond laser writing

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Photonics Research 2024年第3期12卷 I0028-I0040页

作者： ILYA KONDRATYEV VERONIKA IVANOVA SUREN FLDZHYAN ARTEM ARGENCHIEV NIKITA KOSTYUCHENKO SERGEY ZHURAVITSKII NIKOLAY SKRYABIN IVAN DYAKONOV MIKHAIL SAYGIN stanislav STRAUPE ALEXANDER KORNEEV SERGEI KULIK Quantum Technology Centre and Faculty of Physics M.V.Lomonosov Moscow State UniversityMoscow 119991Russia Russian Quantum Center Moscow 121205Russia Laboratory of Quantum Engineering of Light South Ural State UniversityChelyabinsk 454080Russia

We introduce a programmable eight-port interferometer with the recently proposed error-tolerant architecture capable of performing a broad class of transformations.The interferometer has been fabricated with femtosecond laser writing,and it is the largest programmable interferometer of this kind to date.We have demonstrated its advantageous error tolerance by showing an operation in a broad wavelength range from 920 to 980 nm,which is particularly relevant for quantum photonics due to efficient photon sources existing in this wavelength range.Our work highlights the importance of developing novel architectures of programmable photonics for information processing.

关键词： interferometer laser femtosecond

伯醇对镍基催化剂在转移氢化反应中的抑制作用研究

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Chinese Journal of Catalysis 2024年第3期58卷 168-179页

作者： Nikolay Nesterov Alexey Philippov Vera Pakharukova Evgeny Gerasimov stanislav Yakushkin Oleg Martyanov 博列斯科夫催化研究所俄罗斯新西伯利亚

本文研究了在转移加氢条件下,不同类型醇作为氢供体对镍基催化剂在苯并呋喃加氢反应中的活性影响.结果表明,使用异丙醇作为氢供体时,苯并呋喃的加氢过程为底物先发生脱芳构化,然后再进行脱氧反应.然而,当使用伯醇如甲醇、乙醇和正丙醇... 详细信息

本文研究了在转移加氢条件下,不同类型醇作为氢供体对镍基催化剂在苯并呋喃加氢反应中的活性影响.结果表明,使用异丙醇作为氢供体时,苯并呋喃的加氢过程为底物先发生脱芳构化,然后再进行脱氧反应.然而,当使用伯醇如甲醇、乙醇和正丙醇作为氢供体时,会导致镍基催化剂的不可逆失活.针对这一现象,进一步研究了伯醇使镍基金属催化剂失活的机理.结果表明,在250°C条件下,催化剂与伯醇的相互作用会导致形成非活性的碳化物Ni_(3)C,并且镍金属颗粒在氧化铝载体表面会发生烧结和偏析.

关键词：苯并呋喃转移加氢超临界共沉淀 Ni催化剂醇

Investigation of Oil Vapours in Hydro-Generator

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Journal of Power and Energy Engineering 2024年第3期12卷 19-30页

作者： Ekaterina Shubina Dmitry Verkhovtsev stanislav Gulay Andrey Lyamin Bureau for the Design of Hydro-Generators JSC “Power Machines” Saint Petersburg Russia Field Tests Department JSC “Power Machines” Saint Petersburg Russia

The article discusses engineering approaches to solving the problem of oil vapours in generators. Due to the design characteristics of each power plant, it is difficult to find a typical solution. Nevertheless, the article suggests ways to reduce the amount of oil mist. For their implementation, a calculation methodology based on the substitution scheme of the hydraulic path of the bearing support unit is created which takes into account the design features of the bearing and the parameters of the environment around the oil bath. The methodology employed is presented. The numerical method of modelling the aerodynamic fields of the entire hydro generator is used to estimate the air flows and pressures in the oil bath zone of the thrust bearing. Additionally, the method made it possible to track suspected oil particles that could get from the thrust-bearing bath into the surrounding area of the generator. Measures are proposed to reduce the level of oil mist through the competent design of the oil vapour removal system from the bearing bath.

关键词： Hydro-Generator Cooling Oil Mist Bearings Fluid Dynamics