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Double balloon enteroscopy and acute pancreatitis

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World Journal of Gastroenterology 2010年第19期16卷 2331-2340页

作者： Marcela Kopacova Ilja Tacheci stanislav Rejchrt Jolana Bartova Jan Bures 2nd Department of Medicine Charles University in PrahaFaculty of Medicine at Hradec KrálovéUniversity Teaching HospitalSokolská581Hradec Králové500 05Czech Republic

Double balloon enteroscopy(DBE)is a new technique, first published and introduced into clinical practice in 2001 by Yamamoto,the inventor of this outstanding *** allows complete visualization,biopsy and treatment of the small ***,we have some experience of this method for evaluation of the complica- tion *** complications are described in 1%-1.7% of *** pancreatitis is a rare complication of the *** incidence of acute pancreatitis after diagnostic DBE is 0.3%in most *** than 50 cases of acute pancreatitis have been described in the literature so *** the contrary,hyperamylasemia after DBE seems to be a rather common *** with acute pancreatitis is supposed to be possible,but not *** causal mechanism of post-DBE acute pancreatitis is uncertain,and there are several theories in the *** most probable cause seems to be a mechanical straining of the endoscope with over-tube on the pancreas or in the papillary area.

关键词： Double balloon endoscopy Gastrointestinal endoscopy Small intestine Hyperamylasemia Acute pancreatitis

Blood pressure and stature in Helicobacter pylori positive and negative persons

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World Journal of Gastroenterology 2014年第19期20卷 5625-5631页

作者： Marcela Kopacova Ilona Koupil Bohumil Seifert Miluska Skodova Fendrichova Jana Spirkova Viktor Vorisek stanislav Rejchrt Tomas Douda Ilja Tacheci Jan Bures 2~(nd)Department of Internal Medicine-Gastroenterology Charles University in PrahaFaculty of Medicine at Hradec KraloveUniversity Teaching Hospital50005 Hradec KraloveCzech Republic Centre for Health Equity Studies Stockholm UniversityKarolinska Institute17177 StockholmSweden Institute of General Practice First Faculty of MedicineCharles University12002 PrahaCzech Republic Institute of Clinical Biochemistry and Diagnostics Charles University in PrahaFaculty of Medicine at Hradec KraloveUniversity Teaching Hospital50005 Hradec KraloveCzech Republic

To evaluate vital signs and body indices in Helicobacter pylori (H. pylori) positive and negative persons. A total of 22 centres entered the study. They were spread over the whole country, corresponding well to the geographical distribution of the Czech population. A total of 1818 subjects (aged 5-98 years) took part in the study, randomly selected out of 38147 subjects. H. pylori infection was investigated by means of a 13C-urea breath test. Data on height, weight, systolic and diastolic blood pressure and heart rate were collected at the clinics of general practitioners. The overall prevalence of H. pylori infection was 30.4% (402/1321) in adults (≥ 18 year-old) and 5.2% (26/497) in children and adolescents (≤ 17 year-old). Once adjusted for age and gender, only a difference in body mass index remained statistically significant with H. pylori positive adults showing an increase of 0.6 kg/m2 in body mass index. Once adjusted for age and gender, we found a difference in height between H. pylori positive and H. pylori negative children and adolescents. On further adjustment for place of residence, this difference became statistically significant, with H. pylori positive children and adolescents being on average 3.5 cm shorter. H. pylori positive adults were significantly older compared to H. pylori negative subjects. Once adjusted for age and gender, H. pylori infection had no impact on body weight, body mass index and vital signs either in adults or children and adolescents. Chronic H. pylori infection appeared to be associated with short stature in children. H. pylori infection did not influence blood pressure, body weight and body mass index either in adults or children and adolescents.

关键词： Epidemiology Helicobacter pylori Czech Republic 13C-urea breath test Blood pressure Heart rate Weight Stature Body mass index

Seismic and Geological Model of Jura Sedimentation from the South-West Part of Tarskii Axle Part

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地学前缘 2009年第S1期16卷 138-138页

作者： Boykov stanislav Geology and Geophysics Department Novosibirsk State University

Seismic attributes have proliferated in the last three decades at a rapid rate and have helped interpreters in making accurate predictions in hydrocarbon exploration and *** sensitive to amplitude, such as impedance inversion and AVO,are widely used for lithological and petrophysical prediction of reservoir *** attributes,such as coherence and curvature,are particularly useful

关键词： axle seismic faults fracture volumetric attributes

The type specimens of European butterflies from the Linnaeus collection(Lepidoptera:Rhopalocera)

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Entomotaxonomia 2021年第4期43卷 268-292页

作者： stanislav K.KORB Russian Entomological Society Nizhny Novgorod BranchP.O.Box 97 Nizhny NovgorodRF-603009 Russia

The status of primary types of European butterflies established by *** is *** status is confirmed for 38 *** of the following taxa are designated in this paper:Papilio apollo Linnaeus,1758;*** Linnaeus,1758 and *** Linnaeus,*** the following 18 species-group taxa,the status of primary types changed from lectotypes to holotypes(by monotypy)due to their presence in the Linnean collection by single specimens:Papilio aglaja Linnaeus,1758;*** Linnaeus,1758;*** Linnaeus,1767;*** Linnaeus,1758;*** Linnaeus,1758;*** Linnaeus,1764;*** Linnaeus,1758;*** Linnaeus,1761;*** Linnaeus,1758;*** Linnaeus,1758;*** Linnaeus,1758;*** Linnaeus,1758;*** Linnaeus,1767;*** Linnaeus,1758;*** Linnaeus,1758;*** Linnaeus,1758;*** Linnaeus,1758 and *** Linnaeus,*** that do not have a pronounced sexual dimorphism and bright and contrasting coloration in the Linnean collection are represented in most cases by a single type *** largest,brightest and most beautiful butterflies in the Linnean collection have a type series of the maximum size(4 specimens).There are no series of 5 or more specimens for European butterflies in Linnaeus’collection.

关键词： butterflies Europe nomenclature primary types

Comparative study in vivo of the osseointegration of 3D-printed and plasma-coated titanium implants

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World Journal of Orthopedics 2023年第9期14卷 682-689页

作者： stanislav Bondarenko Volodymyr Filipenko Nataliya Ashukina Valentyna Maltseva Gennadiy Ivanov Iurii Lazarenko Dmytro Sereda Ran Schwarzkopf Department of Joint Pathology Sytenko Institute of Spine and Joint Pathology National Academy of Medical Sciences of UkraineKharkiv 61024Ukraine Laboratory of Connective Tissue Morphology Sytenko Institute of Spine and Joint Pathology National Academy of Medical Sciences of UkraineKharkiv 61024Ukraine Experimental Pathology Sytenko Institute of Spine and Joint Pathology National Academy of Medical Sciences of UkraineKharkiv 61024Ukraine Department of Traumatology Military medical clinical center of the Central regionVinnytsia 21018Ukraine Department of Surgery Odesa city hospital 11Odesa 65006Ukraine Hospital for Joint Diseases NYU Langone Orthopedic HospitalNY 10003United States

BACKGROUND Total hip arthroplasty is a common surgical treatment for elderly patients with osteoporosis,particularly in postmenopausal *** such cases,highly porous acetabular components are a favorable option in achieving ***,further discussion is needed if use of such acetabular components is justified under the condition of normal bone *** To determine the features of osseointegration of two different types of titanium implants[3-dimensional(3D)-printed and plasma-coated titanium implants]in bone tissue of a distal metaphysis in a rat femur *** This study was performed on 20 white male laboratory rats weighing 300-350 g aged 6 *** were divided into two groups of 10 animals,which had two different types of implants were inserted into a hole defect(2×3 mm)in the distal metaphysis of the femur:GroupⅠ:3D-printed titanium implant(highly porous);GroupⅡ:Plasma-coated titanium *** 45 and 90 d following surgery,the rats were sacrificed,and their implanted femurs were extracted for histological *** relative perimeter(%)of bone trabeculae[bone-implant contact(BIC%)]and bone marrow surrounding the titanium implants was *** Trabecular bone tissue was formed on the 45th day after implantation around the implants regardless of their type.45 d after surgery,group I(3D-printed titanium implant)and groupⅡ(plasma-coated titanium implant)did not differ in BIC%(83.51±8.5 vs 84.12±1.73;P=0.838).After 90 d,the BIC%was higher in group I(87.04±6.99 vs 81.24±7.62;P=0.049),compared to groupⅡ.The relative perimeter of the bone marrow after 45 d did not differ between groups and was 16.49%±8.58%for groupⅠ,and 15.88%±1.73%for groupⅡ.Futhermore,after 90 d,in groupⅠthe relative perimeter of bone marrow was 1.4 times smaller(12.96±6.99 vs 18.76±7.62;P=0.049)compared to the relative perimeter of bone marrow in groupⅡ.CONCLUSION The use of a highly porous titanium implant,manufactured with 3D printing,for acetabular com

关键词： Rats Hip arthroplasty Femur Porosity 3-dimensional printing Microscopy

Visual guidelines and tutoring in pediatric urological surgery

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Current Urology 2024年第1期18卷 18-22页

作者： stanislav Kotcherov Shahar Rotem Jawdat Jaber Galit Avraham Gennady Lev Michal Darmon Yudith Gabay Boris Chertin Department of Pediatric Urology Shaare Zedek Medical CenterFaculty of MedicineHebrew UniversityJerusalemIsrael Department of Pediatric Surgery Shaare Zedek Medical CenterFaculty of MedicineHebrew UniversityJerusalemIsrael The Operation Room Shaare Zedek Medical CenterJerusalemIsrael

Background:The aim of this prospective randomized study was to evaluate the impact of visual guidelines(picture book)and parents tutoring on pediatric urological surgery on parent's stress and anxiety,the number of postoperative contacts,and *** and methods:Following institutional ethical committee approval,a special picture book reflecting different stages of the convalescent period following multiple types of pediatric urological surgery was *** were randomly divided into 2 groups in which 33 parents in Group 1 received the picture book in addition to routine instructions prior to the surgery and 31 in Group 2 received only routine postoperative *** parents were asked to answer a questionnaire(Amsterdam Preoperative Anxiety and Information Scale)regarding the level of anxiety before surgery and immediately after surgery in the recovery *** number of postoperative parent's calls,nonplaned emergency room visits,and complications were ***:No statistically significant difference in perioperative parental anxiety was found(p=0.88).The visual tutoring group had a significantly lower rate of emergency room admissions(6.6%vs.18.6%,p=0.0433),however parents from this group made a higher number of postoperative calls(9.9%vs.3.1%,p=0.38).Two(6.6%)from the tutoring group expressed their desire to omit visual counseling in future surgical preparation and 4(13.2%)did not have an *** satisfaction with regards to the preoperative counseling and information and the number of postoperative complications was similar in both ***:Visual tutoring does not add any value to parental anxiety but seems helpful in reducing postoperative emergency room *** parents preferred to exclude visual information from future preoperative counseling.

关键词： Anesthesia Children Hypospadias Pediatric case Questionnaires

Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats

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World Journal of Gastroenterology 2017年第43期23卷 7678-7692页

作者： Eva Dolezelova Alena Prasnicka Jolana Cermanova Alejandro Carazo Lucie Hyrsova Milos Hroch Jaroslav Mokry Michaela Adamcova Alena Mrkvicova Petr Pavek stanislav Micuda Department of Biological and Medical Sciences Charles UniversityFaculty of Pharmacy in Hradec Kralove Department of Pharmacology Charles UniversityFaculty of Medicine in Hradec Kralove Department of Pharmacology and Toxicology Charles UniversityFaculty of Pharmacy in Hradec Kralove Department of Medical Biochemistry Charles UniversityFaculty of Medicine in Hradec Kralove Department of Histology and Embryology Charles UniversityFaculty of Medicine in Hradec Kralove Department of Physiology Charles UniversityFaculty of Medicine in Hradec Kralove

AIM To investigate the effect of resveratrol on biliary secretion of cholephilic compounds in healthy and bile duct-obstructed rats. METHODS Resveratrol(RSV) or saline were administered to rats by daily oral gavage for 28 d after sham operation or reversible bile duct obstruction(BDO). Bile was collected 24 h after the last gavage during an intravenous bolus dose of the Mdr1/Mrp2 substrate azithromycin. Bile acids,glutathione and azithromycin were measured in bile to quantify their level of biliary secretion. Liver expression of enzymes and transporters relevant for bile production and biliary secretion of major bile constituents and drugs were analyzed at the m RNA and protein levels using q RT-PCR and Western blot analysis,respectively. The TR-FRET PXR Competitive Binding Assay kit was used to determine the agonism of RSV at the pregnane X receptor. RESULTS RSV increased bile flow in sham-operated rats due to increased biliary secretion of bile acids(BA) and glutathione. This effect was accompanied by the induction of the hepatic rate-limiting transporters for bile acids and glutathione,Bsep and Mrp2,respectively. RSV also induced Cyp7 a1,an enzyme that is crucial for bile acid synthesis; Mrp4,a transporter important for BA secretion from hepatocytes to blood; and Mdr1,the major apical transporter for xenobiotics. The findings were supported by increased biliary secretion of azithromycin. The TR-FRET PXR competitive binding assay confirmed RSV as a weak agonist of the human nuclear receptor PXR,which is a transcriptional regulator of Mdr1/Mrp2. RSV demonstrated significant hepatoprotective properties against BDO-induced cirrhosis. RSV also reduced bile flow in BDO rats without any corresponding change in the levels of the transporters and enzymes involved in RSV-mediated hepatoprotection. CONCLUSION Resveratrol administration for 28 d has a distinct effect on bile flow and biliary secretion of cholephilic compounds in healthy and bile duct-obstructed rats.

关键词： Resveratrol Bile production Bile acids Pregnane X receptor Azithromycin

Heart failure and chronic obstructive pulmonary disease: Two for tea or tea for two?

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World Journal of Cardiology 2010年第10期2卷 305-307页

作者： stanislav Suskovic Mitja Kosnik Mitja Lainscak Department for Clinical Audit University Clinic for Respiratory and Allergic Diseases Golnik University Clinic for Respiratory and Allergic Diseases Golnik Division of Cardiology University Clinic for Respiratory and Allergic Diseases Golnik Applied Cachexia Research Department of Cardiology Charité Campus Virchow-Klinikum

A combination of chronic obstructive pulmonary disease (COPD) and heart failure (HF) is common yet it is inadequately and rarely recognized. Because of the similar clinical manifestations, comorbidity is frequently not considered and appropriate diagnostic tests are not performed. It is very important that a combination of COPD and HF is recognized as these patients have a worse prognosis than patients with an individual disease. When present, COPD should not prevent the use of life-saving therapy in patients with HF, particularly β-blockers. Despite clear evidence of the safety and tolerability of cardioselective β-blockers in COPD patients, these drugs remain grossly underprescribed and underdosed. Routine spirometry and echocardiography in HF and COPD patients, respectively, is therefore warranted to improve current clinical practice.

关键词： Heart failure Chronic obstructive pulmonary disease Spirometry β blocker Inflammation

Frequency-Concentration Dependence of Optical Activity of a Non-Ideal 1D-Superlattice

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Journal of Modern Physics 2011年第12期2卷 1574-1578页

作者： Vladimir V. Rumyantsev stanislav A Fedorov 不详

In the present work the widths of layers constituting the non-ideal superlattice are much bigger then the characteristic scales of space dispersion. In such a case the contribution of individual layers to gyrotropy can be regarded as independed. Thus the corresponding optical quantities can be expressed through the layers’ gyrotropic characteristics. This approach is applied to calculate the specific rotation angle of plane of polarization of light propagating through a nonideal 1D-superlattice, which varies in composition as well as in layers’ width. We carry out numerical calculation of the frequency dispersion of optical activity of a non-ideal superlattice, which includes impurity layers with point defects.

关键词： Light Propagation Non-Ideal 1D-Superlattice Optical Activity Exciton Region of the Spectrum