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COVID-19病人出院后3个月和1年后的CT肺部异常

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国际医学放射学杂志 2022年第4期 480-480页

作者： B.Vijayakumar J.Tonkin A.devaraj K.E.J.Philip C.M.Orton S.R.Desai P.L.Shah 刘雪丹

摘要目的在长达1年的随访中，评估出院新型冠状病毒肺炎（COVID-19）病人的症状、功能损害和在连续胸部CT扫描中显示的残余肺异常。资料与方法作为一项针对

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液相色谱-串联质谱法测定辣木及萝卜叶的提取物中所含的槲皮素、芦丁及山柰酚(英文)

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中西医结合学报 2011年第9期9卷 1022-1030页

作者： Venkatapura C. devaraj Burdipad G. Krishna Gollapalle L. Viswanatha Department of Pharmacology Bioneeds Laboratory Animals and Preclinical Services Department of Pharmacognosy R.R College of Pharmacy Department of Pharmacology People's Education Society College of Pharmacy

目的：通过一种快速、敏感的液相色谱-串联质谱法测定辣木（Moringa oleifera Lam.）及萝卜（Raphinus sativus Linn.）叶的提取物中所含的槲皮素、芦丁及山柰酚。方法：使用冷浸法（90%乙醇）对辣木及萝卜叶进行提取。提取物与0.2%甲... 详细信息

目的：通过一种快速、敏感的液相色谱-串联质谱法测定辣木（Moringa oleifera Lam.）及萝卜（Raphinus sativus Linn.）叶的提取物中所含的槲皮素、芦丁及山柰酚。方法：使用冷浸法（90%乙醇）对辣木及萝卜叶进行提取。提取物与0.2%甲酸和氰化甲烷混合后以0.4mL/min的速度通过Phenomenex Gemini C18色谱层析柱,通过时间为5.01min。结果：串联质谱法测定的离子转换分别为槲皮素303.03~153.1,芦丁611.1~303.1,山柰酚287.1~153.2,内参180.1~110.1。对槲皮素、芦丁及山柰酚定量测量的最低浓度为5ng/mL,线性分布为5~2000ng/mL。槲皮素、芦丁及山柰酚的线性回归系数分别为0.9946、0.9951及0.9969。结论：本研究的结果证明了液相色谱-串联质谱法具有快速、灵敏的特点,对于同时测定辣木及萝卜叶的提取物中所含的槲皮素、芦丁及山柰酚有较好的特异性。

关键词：辣木萝卜植物提取物槲皮素芦丁山柰酚色谱法,液相串联质谱法

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纤维性特发性间质性肺炎:HRCT表现预测死亡率

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国际医学放射学杂志 2011年第5期 501-502页

作者： A.J.Edey A.A.devaraj R.P.Barker A.G.Nicholson A.U.Wells D.M.Hansell 沈晶 Department of Radiology The Royal Brompton Hospital

目的本研究旨在探讨难行肺活检的纤维性特发性间质性肺炎(IIP)病人HRCT表现及其对预后的评估价值。方法 146例纤维性IIP病人被纳入本研究,所有病人均行HRCT检查。观察所有病人肺组织异常的范围,纤细与粗糙

关键词：特异性间质性肺炎纤维化 CT 预后肺

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CT和超声心动图联合应用检测门静脉肺高压

国际医学放射学杂志 2014年第6期 603-604页

作者： A.devaraj R.Loveridge D.Bosanac K.Stefanidis W.Bernal S.R Desai 胡晓飞 Department of Radiology King’s Health PartnersKing’s College LondonKing’s College Hospital NHS Foundation TrustDenmark HillLondon SE5 9RSUK

摘要目的分析肝脏疾病病人CT肺动脉高压征象和平均肺动脉压(m PAP)的相关性,并确定CT在联合超声心动图诊断门静脉肺高压中的作用。方法对49例肝移植病人进行

关键词：门静脉门脉系统肺高压超声心动图超声波诊断 CT

MDC、超声心动图及两者联合检测肺动脉高压

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国际医学放射学杂志 2010年第2期 187-188页

作者： A.devaraj A.U.Wells M.G.Meister T.J.Corte S.J.Wort D.M.Hansell 范丽 Department of Radiology Royal Brompton HospitalSydney StreetLondonSW 36NPEngland

目的评价MDCT测量值检测肺动脉高压的可靠性,且进一步确定MDCT和超声心动图的联合应用对肺动脉高压的检测是否比两者单独检测更具有预测价值。材料与方法此项回

关键词：超声心动图相关性平均超声波诊断肺动脉压 MDC

混合多维MR成像无创性评估前列腺组织成分来诊断前列腺癌的价值:一项可行性研究

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国际医学放射学杂志 2018年第4期 481-481页

作者： A.Chatterjee R.M.Bourne S.Wang A.devaraj A.J.Gallan T.Antic 郑娇凤 Department of Radiology University of Chicago

目的探讨混合多维MR成像的分区分析是否可应用于诊断前列腺癌并明确其侵袭性。材料与方法对22例前列腺癌病人行术前3.0 T MR成像。对不同回波时间（47、75、100 ms）和不同b值（0、750、1 500 s/mm2）分别进行组合,获得混合多维MR成像... 详细信息

目的探讨混合多维MR成像的分区分析是否可应用于诊断前列腺癌并明确其侵袭性。材料与方法对22例前列腺癌病人行术前3.0 T MR成像。对不同回波时间（47、75、100 ms）和不同b值（0、750、1 500 s/mm2）分别进行组合,获得混合多维MR成像横断面影像,并形成与每个体素相关的3×3阵列数据。将混合数据拟合到三区信号模型,计算各分区的表观扩散系数（ADC）和T2值,计算前列腺各区带组织间质、上皮和腺泡腔的体积。测量经前列腺切除术确诊的恶性肿瘤组织的兴趣区（n=28）和正常前列腺组织（n=71）的体积分数、常规ADC和T2值。采用受试者操作特征（ROC）曲线分析评估各种参数对前列腺癌和前列腺良性组织的鉴别价值。结果与正常组织相比较,混合多维MRI显示前列腺癌上皮组织的体积分数明显增加（分别为23.2%±7.1%∶48.8%±9.2%）,腺泡腔（26.4%±14.1%∶14.0%±5.2%）和基质（50.5%±15.7%∶37.2%±9.1%）的体积分数减小。前列腺各区带组织成分的体积分数显示,Gleason评分与Spearman评分相关系数较T2值（ρ=-0.292,P=0.132）和ADC值（ρ=-0.315,P=0.102）更高（上皮:ρ=0.652,P=0.000 1;基质:ρ=-0.439,P=0.20;腺泡腔:ρ=-0.390,P=0.040）。ROC曲线下面积显示区分前列腺癌与正常前列腺组织时,上皮体积分数（0.991）差异最高,其次为腺泡腔体积分数（0.800）和基质体积分数（0.789）。结论当前列腺癌存在时,前列腺腺泡腔、基质和上皮组织的体积分数显著改变。混合多维MR成像可对这些参数进行无创性测量,并可能有助于提高前列腺癌的诊断并明确其侵袭性。

关键词： MR 上皮组织前列腺癌体积分数无创性

Prevalence of anxiety among gestational diabetes mellitus patients: A systematic review and meta-analysis

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World Journal of Meta-Analysis 2020年第3期8卷 275-284页

作者： Kai Wei Lee Hong Chuan Loh Seng Choi Chong Siew Mooi Ching Navin Kumar devaraj Maiza Tusimin Habibah Abdul Hamid Fan Kee Hoo Department of Family Medicine Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaSerdang 43400SelangorMalaysia Clinical Research Centre Hospital Seberang JayaMinistry of Health MalaysiaPerai 13700PenangMalaysia Department of Psychiatry Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaSerdang 43400SelangorMalaysia Department of Obstetrics and Gynaecology Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaSerdang 43400SelangorMalaysia Department of Medicine Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaSerdang 43400SelangorMalaysia

BACKGROUND A diagnosis of gestational diabetes mellitus(GDM)negatively influences maternal mental *** is a lack of systematic review and meta-analysis on prevalence of anxiety among GDM *** To pool data from existing literature to determine the pooled estimates for the prevalence of anxiety among women diagnosed with *** We searched multiple databases including MEDLINE,Cinahl,PubMed and Scopus to identify studies published up to 31 October 2019 with data on the prevalence of anxiety among women diagnosed with *** were extracted from published *** were pooled using random-effects *** We reviewed 19 abstracts,retrieved 10 articles and included three studies incorporating 12744 GDM women from three *** pooled prevalence of anxiety was 29.5%(95%CI:6.9,52.0)among GDM *** Prevalence of anxiety among GDM women was *** suggest that epidemiological studies on anxiety should be conducted urgently as it merits clinical *** addition,it is important to identify factors associated with anxiety among women diagnosed with GDM.

关键词： Prevalence Anxiety Gestational diabetes Psychiatry Meta-analysis Systematic review

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HIV患者肛门鳞状异常增生的期待治疗

世界核心医学期刊文摘（胃肠病学分册） 2006年第8期2卷 6-6页

作者： devaraj B. Cosman B. C. 陈云茹(译) 史敏(校) Cosman Surgical Service (112E) VA San Diego Healthcare System 3350 La Jolla Village Drive San Diego CA 92161- 0002 United State 不详

PURPOSE: Anal squamous dysplasia is commonly found in patients with HIV infection. There is no satisfactory treatment that eradicates this premalignant lesion with low morbidity and low recurrence. This study reviews a series of patients with HIV and an abnormal anal examination who had squamous dysplasia and who have been followed with physical examination alone and with repeat biopsies as necessary for new or suspicious lesions. METHODS:We reviewed the charts of 40 HIV- positive men who had squamous dysplasia of the anal canal and anal margin, focusing on history, physical findings, histologic diagnosis, and the occurrence of invasive squamous-cell carcinoma. RESULTS: Forty HIV-positive men (mean age 39 years) were followed for anal squamous dysplasia. Biopsies revealed dysplasia, which was usually multifocal. The grade of dysplasia varied, but 28 of 40 patients had at least one area of severe dysplasia. All patients had a follow-up period greater than one year (mean, 32 months; range, 13- 130 months). Three patients developed invasive carcinoma while under surveillance, and these were completely excised or cured with chemoradiation. CONCLUSIONS: Extensive excision for dysplasia in the context of HIV confers high morbidity and questionable benefit, and other treatments are of uncertain value. In a group of patients followed expectantly, most did not develop invasive cancer, and in those who did, early cancers could be identified and cured. Physical examination surveillance for invasive carcinoma may be acceptable for following patients with HIV and biopsy-proven squamous dysplasia.

关键词：鳞状上皮细胞癌 HIV患者异常增生肛门期待治疗 HIV阳性患者 HIV感染者随访期间癌前病变浸润性癌

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Prevalence,awareness and control of hypertension in Malaysia from 1980-2018:A systematic review and meta-analysis

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World Journal of Meta-Analysis 2020年第4期8卷 320-344页

作者： Man Jun Soo Zhen Yee Chow Siew Mooi Ching Chun Han Tan Kai Wei Lee Navin Kumar devaraj Hani Syahida Salim Vasudevan Ramachandran Poh Ying Lim Dhashani Sivaratnam Fan Kee Hoo Ai Theng Cheong Yook Chin Chia Department of Family Medicine Universiti Putra MalaysiaSerdang 43400Malaysia Hospital Seberang Jaya Perai 13700Malaysia Malaysian Research Institute on Ageing Universiti Putra MalaysiaSerdang 43400Malaysia Department of Community Health Universiti Putra MalaysiaSerdang 43400Malaysia Department of Surgery Universiti Putra MalaysiaSerdang 43400Malaysia Department of Medicine Universiti Putra MalaysiaSerdang 43400Malaysia Department of Medical Sciences Sunway UniversityBandar Sunway 47500Malaysia

BACKGROUND Hypertension is a common public health problem worldwide and is a well-known risk factor for increased risk of cardiovascular diseases,contributing to high morbidity and ***,there has been no systematic review and meta-analysis of a multiethnic population such as that of *** To determine the trend in prevalence,awareness and control rate of hypertension in *** Systematic searches were conducted in six databases(PubMed,Scopus,Ovid,CINAHL,Malaysian Medical Repository and Malaysia Citation Index)for articles published between 1980 and *** authors reviewed the studies and performed quality assessment and data extraction *** estimates of hypertension prevalence,awareness and control rate were calculated using the DerSimonian-Laird random-effects *** and sensitivity analyses were *** We included 56 studies involving a total of 241796 *** overall pooled prevalence of hypertension aged≥18 years was 29.7%.The prevalence of hypertension was the lowest in the 1980s(16.2%,95%confidence interval(CI):13.4,19.0),increasing up to 36.8%(95%CI:6.1,67.5)in the 1990s,then decreasing to 28.7%(95%CI:21.7,35.8)in the 2000s and 26.8%(95%CI:21.3,32.3)in the *** prevalence of awareness was 51.4%(95%CI:46.6,56.3),while 33.3%(95%CI:28.4,38.2)of those on treatment had achieved control of their blood *** In Malaysia,three in ten adults aged≥18 years have hypertension,while four in ten adults aged≥30 years have *** out of ten people are aware of their hypertension status and only one-third of those under treatment achieved control of their *** efforts by policymakers and healthcare professionals to improve awareness and control of hypertension should be of high priority.

关键词： Prevalence Awareness Control Hypertension Blood pressure Malaysia Systematic review Meta-analysis