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<i>“Withered Tree” Concept Host</i>, Achieved by Global Contraception and Abortion, Secondary to Fragmented Germ Cells, Agonizingly Reduced Endogenous Estrogen/Androgen, Defaulted Genomic Repertoire, Deranged Cell Metabolism, Metabolic Syndrome, <i>Result in Failure of Pharmacological Therapeutics with Advanced Technologies</i>

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Open Journal of Preventive Medicine 2015年第4期5卷 186-195页

作者： Elizabeth Jeya Vardhini Samuel Nagarajan Natarajan sri kumar Department of General Medicine MM Hospital Tanjore India Department of General Medicine Pondicherry Institute of Medical Sciences Pondicherry India Dhonavur Fellowship Hospital Dhonavur India

Background: In spite of advanced technologies and drug discoveries, morbidity and mortality were undoubtedly increasing in the era of contraception and abortion. Aims: Altruistic correlation of increasing morbidity, mortality, with contraception, abortion was planned for. Methods: In 2012, a retrospective analysis of prevalence of mortality in 350 patients of 20 - 35 years, 35 - 50 years and >50 years from data collected between 2003 and 2012 by convenient, stratified random sampling, from community, hospital, and its association with contraception and abortion status was undertaken;simultaneously, serum estrogen levels obtained from 105 patients were analyzed. In 2014, randomly chosen 8 males, of the 3 age groups, from a different community, whose life partners had undergone sterilization, were assessed for their serum testosterone levels. Results: Contraception users exhibited 3 - 4 fold increased mortality [p 50 years [p < 0.0005]. Endogenous estrogen was reduced in 75% [p < 0.0005] of contraceptive users. Plasma testosterone was reduced in males observing contraception, to less than 50% of normal, e.g. 1.3 ng/ml;66.6% contraception users aged 20 - 35 years had reduced [p < 0.0005] testosterone;100% of male contraception users aged 36 - 70 years showed reduced testosterone [p < 0.0005]. Conclusion: The “withered tree akin host” concept is contraception, abortion, with smashed fragmentation of germ cells. Reduced endogenous estrogen, androgen [dried up, destroyed life factors] result in deranged cell metabolism, cell cycle, and defaulted genomic repertoire, leading to failure of all established pharmacological therapeutics, including advanced technologies which yield gratifying results in non contracepted people today and in every one, before the era of contraception;subsets of people, host with contraception, with destroyed life factors, behave helplessly, concerning therapeutic applications, compared with subsets of people, host without contraception, with intac

关键词： “Withered Tree” Concept Host Achieved by Global Contraception and Abortion Secondary to Fragmented Germ Cells Agonizingly Reduced Endogenous Estrogen/Androgen Defaulted Genomic Repertoire Deranged Cell Metabolism Metabolic Syndrome Result in Failure of Pharmacological Therapeutics with Advanced Technologies

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Performance of Bacillus tropicus on Mechanical,Durable and Crack Remediation Properties in Sustainable Vermiculite Concrete

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Journal of Bionic Engineering 2024年第4期21卷 1987-1999页

作者： Anbazhagan Rajesh Venkatesh sri Hariny Arunachalam Sumathi School of Civil Engineering SASTRA Deemed to be UniversityThirumalaisamudramThanjavurTamilnadu613401India

Sustainable cement-based concrete materials are primarily used for construction,among which vermiculite as lightweight fine aggregate gains more future development ***,a bacterial solution was sprayed over vermiculite and wrapped using calcium sulphoaluminate(CSA)cement to replace with fine aggregate in ***,based on a preliminary test on compressive strength results,10%of Ground Granulated Blast Furnace Slag(GGBS)and a healing solution proportion of 9:1 was selected for preparing self-healing *** fine aggregate was replaced in concrete using vermiculite in 0%,5%,10%and 15%and the findings suggest that bacterial vermiculite replacement should be at most 5%to achieve better results in strength and durable *** strength enhancement observed for compressive strength,strength regain,split tensile strength,flexural strength,and ultrasonic pulse velocity were 29.22%,45.5%,34.02%,28.03%and 41.4%*** crack healing at 7,14 and 28 days of BIVC was 38.23%,58.82%and 79.41%,which is 3–4%lower than internal crack *** analysis by Scanning Electron Microscopy(SEM),X-Ray Diffractometer(XRD),and Energy Dispersive Spectroscopy(EDS)reveals the existence of calcite,and it was formed due to the bio-mineral action of bacteria with available nutrients in sustainable concrete.

关键词： Bacillus tropicus Vermiculite Ground granulated blast furnace slag Mechanical properties Durable properties Crack healing Microstructural characterization

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Unraveling the role of dual Ti/Mg metals on the ignition and combustion behavior of HTPB-boron-based fuel

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Defence Technology（防务技术） 2024年第2期32卷 134-143页

作者： Arijit Debnath Yash Pal sri Nithya Mahottamananda Djalal Trache School of Aeronautical Science Hindustan Institute of Technology and ScienceChennai 603103India Department of Aerospace Engineering B S Abdur Rahman Crescent Institute of Science and TechnologyChennai 600048India Energetic Materials Laboratory(EMLab) Teaching and Research Unit of Energetic ProcessesEcole Militaire PolytechniqueBP 17Bordj El-Bahri16046AlgiersAlgeria

Metal additives play an essential role in explosive and propellant formulations. Boron(B) is widely used in propellant applications owing to its high energetic content. The addition of B to explosives and propellants increases their energy density, making them more efficient and powerful. Nevertheless, B forms oxide layers on its surface during combustion, slowing down the combustion rate and reducing rocket motor efficiency. To overcome this issue, other metal additives such as aluminum(Al), magnesium(Mg),and titanium(Ti) are revealed to be effective in boosting the combustion rate of propellants. These additives may improve the combustion rate and therefore enhance the rocket motor’s performance. The present study focused on preparing and investigating the ignition and combustion behavior of pure hydroxyl-terminated polybutadiene(HTPB)-B fuel supplemented with nano-titanium and nanomagnesium. The burn rates of HTPB-B fuel samples were evaluated on the opposed flow burner(OFB)under a gaseous oxygen oxidizer, for which the mass flux ranges from 22 kg/(m^(2)·s) to 86 kg/(m^(2)·s). The addition of Ti and Mg exhibited higher regression rates, which were attributed to the improved oxidation reaction of B due to the synergetic metal combustion effect. The possible combustion/oxidation reaction mechanism of B-Mg and B-Ti by heating the fuel samples at 900℃ and 1100℃ was also examined in a Nabertherm burnout furnace under an oxygen atmosphere. The post-combustion products were collected and further subjected to X-ray diffraction(XRD) and field emission scanning electron microscopy(FE-SEM) analyses to inspect the combustion behavior of B-Ti and B-Mg. It has been observed that the B oxide layer at the interface between B-Ti(B-Mg) is removed at lower temperatures, hence facilitating oxygen transfer from the surroundings to the core B. Additionally, Ti and Mg decreased the ignition delay time of B, which improved its combustion performance.

关键词： Boron B_(2)O_(3) Opposed flow burner Combustion Magnesium

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KL-SG High-Speed Rail-a catalyst for national economic development sri Viknesh Permalu and Karthigesu Nagarajoo

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Railway Sciences 2024年第3期3卷 265-278页

作者： sri Viknesh Permalu Karthigesu Nagarajoo Department of Transportation Engineering Technology Fakulti Teknologi KejuruteraanUniversiti Tun Hussein Omn MalaysiaPagohMalaysia

Purpose-In an increasingly interconnected world,transportation infrastructure has emerged as a critical determinant of economic growth and global ***-speed rail(HSR),characterized by its exceptional speed and efficiency,has garnered widespread attention as a transformative mode of transportation that transcends borders and fosters economic *** Kuala Lumpur-Singapore(KL-SG)HSR project stands as a prominent exemplar of this paradigm,symbolizing the potential of HSR to serve as a catalyst for national economic ***/methodologylapproach-This paper is prepared to provide an insight into the benefits and advantages of HSR based on proven case studies and references from global HSRs,including China,Spain,France and ***-The findings that have been obtained focus on enhanced connectivity and accessibility,attracting foreign direct investment,revitalizing regional economies,urban development and city regeneration,boosting tourism and cultural exchange,human capital development,regionai integration and environmental and sustainability ***/value-The KL-SG HSR,linking Kuala Lumpur and Singapore,epitomizes the potential for HSR to be a transformative agent in the realm of economic *** project encapsulates the aspirations of two dynamic Southeast Asian economies,united in their pursuit of sustainable growth,enhanced connectivity and global *** scrutinizing the KLSG High-Speed Rail through the lens of economic benchmarking,a deeper understanding emerges of how such projects can drive progress in areas such as cross-border trade,tourism,urban development and technological innovation.

关键词： High-speed rail Transportation Railways Sustainable mobility Socioeconomic development Technology Papertype Case study

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Evaluating Ignition and Combustion Performance with Al-Metal- Organic Frameworks and Nano-Aluminum in HTPB Fuel

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火炸药学报 2024年第5期47卷 413-421,I0003页

作者： sri Nithya Mahottamananda Yash Pal Yarravarapu Sai sriram Subha S Djalal Trache Department of Aerospace Engineering B S Abdur Rahman CrescentInstitute of Science and TechnologyChennai-600048India School of Aeronautical Science Hindustan Institute of Technologyand ScienceChennai-603103India Energetic Materials Laboratory(EMLab) Teaching and ResearchUnit of Energetic ProcessesEcole Militaire PolytechniqueBP 17Bordj El-Bahri16046AlgiersAlgeria

Incorporating aluminum metal-organic frameworks(Al-MOFs)as energetic additives for solid fuels presents a promising avenue for enhancing combustion *** study explores the potential benefits of Al-MOF(MIL-53(Al))energetic additive on the combustion performance of hydroxyl-terminated polybutadiene(HTPB)*** HTPB-MOF fuel samples were manufactured using the vacuum-casting technique,followed by a comprehensive evaluation of their ignition and combustion properties using an opposed flow burner(OFB)setup utilizing gaseous oxygen as an *** gauge the effectiveness of Al-MOFs as fuel additives,their impact is compared with that of nano-aluminum(nAl),another traditional additive in HTPB *** results indicate that the addition of 15%(mass fraction)nAl into HTPB resulted in the shortest ignition delay time(136 ms),demonstrating improved ignition performance compared to pure HTPB(273 ms).The incorporation of Al-MOF in HTPB also reduced ignition delay times to 227 ms and 189 ms,***,under high oxidizer mass flux conditions(79—81 kg/(m^(2)s)),HTPB fuel with 15%nAl exhibited a substantial 83.2%increase in regression rate compared to the baseline HTPB fuel,highlighting the positive influence of nAl on combustion *** contrast,HTPB-MOF with a 15%Al-MOF additive showed a 32.7%increase in regression rate compared to pure *** results suggest that HTPB-nAl outperforms HTPB-MOF in terms of regression rates,indicating a more vigorous and rapid burning behavior.

关键词： ignition combustion enhancement MOF HTPB regression rate

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警惕美国股票市场和债券市场的潜在风险

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金融发展研究 2013年第7期 41-42页

作者： sri-kumar 王宇 TCW 资产配置委员会中国人民银行研究局

本文认为,目前,美国对世界经济的影响力已经有所下降。从短期看,美国经济复苏还面临一些困难,但从中期看,新能源和制造业可能成为美国经济的引擎。对中国而言,高利率和高汇率可能使中国经济增长放缓,中国应警惕美国股票和债券市场的潜... 详细信息

本文认为,目前,美国对世界经济的影响力已经有所下降。从短期看,美国经济复苏还面临一些困难,但从中期看,新能源和制造业可能成为美国经济的引擎。对中国而言,高利率和高汇率可能使中国经济增长放缓,中国应警惕美国股票和债券市场的潜在风险。

关键词：汇率利率经济增长投资风险

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Laparoscopic plication for diaphragmatic eventration in adults:Unveiling the mystery of eventration

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第2期7卷 92-96页

作者： Balika Mahesan Prasanna kumar Reddy K.S.Santhosh Anand Muvva sri Harsha M Vijay N Sudarsan srikanth Department of Minimal Access Surgery Apollo HospitalsChennaiIndia Department of Surgical Gastroenterology Apollo HospitalsChennaiIndia

Diaphragm eventration is the permanent elevation of a hemidiaphragm and can be due to congenital or acquired *** is a rather uncommon condition in adults and causes a spectrum of symptoms,ranging from asymptomatic incidental findings on imaging to life-threatening respiratory *** patients do not require any treatment,but plication is the conventional,well-known method for treating symptomatic *** varies depending on the *** this article,we discuss two rare cases of diaphragmatic eventration that were treated with minimal access surgery.

关键词： Diaphragmatic eventration Minimal access surgeryLaparoscopy

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Trends in mortality among the geriatric population undergoing Surgical aortic valve replacement (SAVR) and potential racial disparities: a 20-year perspective via the National (Nationwide) Inpatient Sample

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Journal of Geriatric Cardiology 2024年第7期21卷 716-722页

作者： Nomesh kumar Kamleshun Ramphul FNU Bawna Nitish Behary Paray Mansimran Si-ngh Dulay Jasninder Singh Dhaliwal Shruti Aggarwal Sebastian Mactaggart Suma sri Chennapragada Shaheen Sombans Renuka Verma Hemamalini Sakthivel Raheel Ahmed Department of Internal Medicine Detroit Medical Center Sinai Grace-Wayne State UniversityMichiganUSA In-dependent Researcher TrioletMauritius Independent researcher Farmington HillsMichiganUSA Royal Devon University Healthcare NHS Foundation Trust ExeterUnited Kingdom Royal Brompton Hospital part of Guy’s and St.Thomas’NHS Foundation TrustLondonUnited Kingdom Department of Internal Medicine University of Cali-forniaRiversideUSA Independent Researcher New DelhiIndia Northumbria Hospitals NHS Foundation Trust NewcastleUnited Kingdom Department of Internal Medicine Louisiana State UniversityShreveportUSA Sha-heen Sombans Independent ResearcherHyderabadIndia Department of Internal Medicine Kirk Kerkorian School of Medicine at UNLVLas VegasUSA One Brooklyn Health System/Interfaith Medical Ctr Program BrooklynNYUSA

Background Racial disparities in cardiovascular conditions are well *** similar race-based discrepancies in health outcomes also exist among elderly patients undergoing surgical aortic valve replacement(SAVR) for aortic stenosis remains *** We abstracted data from the National(Nationwide) Inpatient Sample over a 20-year period from 2001 to 2020 using specific ICD-9 and ICD-10 *** included patients aged ≥ 60 and ≤ 80 years with races recorded as White,African American,or Hispanic at the time of their hospitalization for *** analyzed and reported the baseline characteristics,risk-adjusted inhospital mortality,and complications stratified by *** Of 420,181 patients studied,90.0% identified as White,4.0% as African American and 6.0% as *** a decrease in overall in-hospital mortality rates from 3.8% between 2001-2005 to 1.8% between 2016-2020,African Americans had higher odds of all-cause in-hospital deaths compared to Whites(a OR = 1.390,P < 0.001).Additionally,they were more likely to experience cardiogenic shock(a OR = 1.241,P < 0.001) and acute kidney injury(a OR = 1.314,P < 0.001) as well as more likely to require organ support such as IABP use(a OR = 1.336,P < 0.001) or invasive mechanical ventilation(a OR = 1.342,P < 0.001).Interestingly,African Americans were less likely to report events of acute ischemic stroke compared to Whites(a OR = 0.852,P < 0.001).Conclusions Despite a reassuring reduction in overall in-hospital mortality rates of geriatric patients undergoing SAVR for aortic stenosis,racial disparities in health outcomes remain pervasive with minorities more likely to report higher in-hospital morbidity and mortality.

关键词： mortality likely spite

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Simulation and experimentation of Propeller-Savonius turbine tested underwater surface

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CLEAN ENERGY 2024年第3期8卷 20-33页

作者： Wuryanti, sri Sasono, Teguh Manunggal, Bambang P. Mursanto, Wahyu B. Sugianto Politekn Negeri Bandung Politeknik Negeri Bandung Bandung Indonesia Politekn Negeri Padang Dept Mech Engn Padang Indonesia

Indonesia's vast maritime territory offers a unique opportunity for harnessing the potential Energy of seawater currents. This study explores the effectiveness of a combined Savonius and propeller-type turbine system. The Savonius turbine, known for its efficiency in capturing ocean currents due to its large sweep area, is combined with a propeller-type turbine to enhance rotational speed and power generation. A novel approach is employed to induce turbulence and optimize energy extraction, first channeling water through the propeller turbine and then into the Savonius turbine. A comprehensive investigation is conducted through simulations and experimental tests within a controlled tunnel environment. The study explores the performance of two-bladed and three-bladed Propeller-Savonius configurations at varying inlet water velocities (0.1, 0.3, 0.6 and 1.0 m/s). The simulation incorporates a turbulence model with 5% intensity and a hydraulic diameter of 0.216 m. Results indicate that the proposed configuration achieves a maximum power output of 2.0293 W with an impressive efficiency of 63.339% in simulation. Concurrently, experimental testing yields a peak efficiency of 61.335% and turbine power of 0.3951 W. The findings demonstrate the feasibility of the combined turbine system and highlight the importance of turbulence in optimizing energy extraction from seawater currents. This research contributes valuable insights into the design and performance of hybrid turbines for harnessing oceanic Energy, emphasizing the potential for sustainable power generation in maritime regions. The methodology and results presented herein offer a foundation for further exploration and refinement of seawater current energy conversion technologies. The study combines a Savonius turbine and a propeller turbine to enhance rotational speed and power generation. CFD simulations and experiments document performance at different water velocities. The findings show that this system is promisi

关键词： hydro-turbine propeller -Savonius renewable energy water WIND TURBINE PERFORMANCE BLADES CFD RATIO

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Hepatitis B virus genotypes in precision medicine of hepatitis Brelated hepatocellular carcinoma:Where we are now

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1097-1103页

作者： Caecilia H C Sukowati sri Jayanti Turyadi Turyadi David H Muljono Claudio Tiribelli Eijkman Research Center for Molecular Biology Research Organization for HealthNational Research and Innovation Agency of IndonesiaJakarta 10340Indonesia Liver Cancer Unit Fondazione Italiana Fegato ONLUSTrieste 34149Italy Faculty of Medicine Hasanuddin UniversityMakassar 90245South SulawesiIndonesia Faculty of Medicine and Health University of SydneySydney 2050Australia

Hepatitis B virus(HBV)infection is a major player in chronic hepatitis B that may lead to the development of hepatocellular carcinoma(HCC).HBV genetics are diverse where it is classified into at least 9 genotypes(A to I)and 1 putative genotype(J),each with specific geographical distribution and possible different clinical outcomes in the *** diversity may be associated with the precision medicine for HBV-related HCC and the success of therapeutical approaches against HCC,related to different pathogenicity of the virus and host *** Editorial discusses recent updates on whether the classification of HBV genetic diversity is still valid in terms of viral oncogenicity to the HCC and its precision medicine,in addition to the recent advances in cellular and molecular biology technologies.

关键词： Hepatitis B virus Hepatocellular carcinoma Genotypes Pathogenesis Precision medicine

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