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Neurocognitive outcomes in pediatric brain tumors after treatment with proton versus photon radiation:a systematic review and meta-analysis

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World Journal of Pediatrics 2023年第8期19卷 727-740页

作者： Álvaro Lassaletta Javier S.Morales Pedro L.Valenzuela Borja Esteso Lisa S.Kahalley Donald J.Mabbott soumya unnikrishnan Elena Panizo Felipe Calvo Radiation Oncology Department Clínica Universidad de NavarraCalle Marquesado de Santa Marta 128027 MadridSpain Pediatric Neuro-Oncology Unit Hospital Infantil Universitario Niño JesúsMadridSpain MOVE-IT Research Group Department of Physical EducationFaculty of Education SciencesUniversity of CadizCádizSpain Biomedical Research and Innovation Institute of Cádiz(INiBICA)Research Unit Puerta del Mar University HospitalUniversity of CádizCádizSpain Physical Activity and Health Research Group(PaHerg) Research Institute of the Hospital 12 de Octubre(‘imas12’)MadridSpain Systems Biology Department University of AlcaláMadridSpain Clinical Neuropsychology Unit Psychiatry and Clinical Psychology DepartmentHospital Infantil Universitario Niño JesúsMadridSpain Baylor College of Medicine HoustonTXUSA Texas Children’s Hospital HoustonTXUSA The Hospital for Sick Children TorontoONCanada The University of Toronto TorontoONCanada University of California School of Medicine San DiegoLa JollaCAUSA

Background Advances in cancer treatments,particularly the development of radiation therapy,have led to improvements in survival outcomes in children with brain ***,radiation therapy is associated with significant long-term neurocognitive *** present systematic review and meta-analysis aimed to compare the neurocognitive outcomes of children and adolescents with brain tumors treated with photon radiation(XRT)or proton therapy(PBRT).Methods A systematic search was conducted(PubMed,Embase,Cochrane,and Web of Science from inception until 02/01/2022)for studies comparing the neurocognitive outcomes of children and adolescents with brain tumors treated with XRT *** pooled mean differences(expressed as Z scores)were calculated using a random effects method for those endpoints analyzed by a minimum of three *** Totally 10 studies(n=630 patients,average age range:1–20 years)met the inclusion *** who had received PBRT achieved significantly higher scores(difference in Z scores ranging from 0.29–0.75,all P0.05 in main analyses or sensitivity analyses)were found for nonverbal memory,verbal working memory and working memory index,processing speed index,or focused *** Pediatric brain tumor patients who receive PBRT achieve significantly higher scores on most neurocognitive outcomes than those who receive *** studies with long-term follow-ups are needed to confirm these results.

关键词： Brain health Childhood cancer Intelligence quotient Radiotherapy

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Isolated Systolic Hypertension in Geriatrics

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International Journal of Clinical Medicine 2025年第1期16卷 29-53页

作者： soumya Erri Terry Oroszi Department of Pharmacology & Toxicology Boonshoft School of Medicine WSU Fairborn OH USA

Hypertension, often called the “silent killer”, is a major risk factor for heart attacks and strokes in the elderly. Its effective management is crucial to prevent damage to the heart, brain, and kidneys. Isolated systolic hypertension (ISH) is particularly critical in the elderly population. Cardiovascular risk factors, including pulse pressure and wave velocity, are closely associated with systolic blood pressure and influenced by arterial stiffness and wave reflections. Managing ISH is complex due to the potential negative effects of certain medications and individual variability in treatment response. This paper will address these issues, evaluating antihypertensive drugs, combination therapy, personalized treatment plans, and updated guidelines for managing ISH.

关键词： Hypertension Geriatric or Elderly or Adults Types of Hypertension Tests First-Line Treatment Drugs Isolated Systolic Hypertension Other Diseases

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Determination of Fungal Species to Investigate the Aflatoxin Contamination in Rice(Oryza sativa L.)

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Phyton-International Journal of Experimental Botany 2025年第2期94卷 407-420页

作者： Eman Alhomaidi Aisha Umar Mustansar Mubeen Laurent Dufossé Yasir Iftikhar Arpita Das soumya Ghosh Muhammad Sibt-e-Abbas Department of Biology College of SciencePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Institute of Botany University of the PunjabLahore54000Pakistan Department of Plant Pathology College of AgricultureUniversity of SargodhaSargodha40100Pakistan Universitéde La Réunion Laboratoire CHEMBIOPRO(Chimie et Biotechnologie des Produits Naturels)ESIROI Département agroalimentaire15 avenue RenéCassinSaint-DenisF-97490France Department of Biotechnology Adamas UniversityBarasat-Barrackpore Road24 Parganas NorthJagannathpurKolkata700126West BengalIndia Natural and Medical Sciences Research Center University of NizwaNizwa616Oman Department of Food Science&Technology Faculty of Food&Home SciencesMNS-University of AgricultureMultan630496Pakistan

Aspergillus species produce aflatoxins and raise concerns about food safety in departmental stores and manufacturing *** address the risks posed by aflatoxins,and to advise the public on the highest quality rice that serves as a nutritious food source,an inquiry following the guidelines outlined in both local and international standards of food safety for the presence of aflatoxins is an essential ***,16 white rice samples were selected randomly from low/high socio-economic departmental stores from 16 different *** powdered rice filtrate was extracted using *** filtrate applied on TLC plates and the amount of aflatoxin and moisture contents were *** the non-infected rice,moisture content was low(9.08%)whereas high[13.65%>12%(standard>value)]in infected *** out of 8 samples of low-quality rice were contaminated with AFB_(1) and AFB_(2)(ranging from 22.2 to 29.3μg/kg).All the samples except one(22.3μg/kg)from high-quality rice were certified fit despite the contamination with AFB_(1).Furthermore,phylogenetic analysis showed Aspergillus flavus from unfit low(Long grain brown and Brown basmati)and high-quality(Basmati-198)rice whereas *** from unfit low-quality Medium-grain brown *** presented research proves that the detection of fungi and aflatoxins in rice grains poses a huge risk to the health of ***,it is necessary to check the rice grains before distribution.

关键词： Mycotoxin aflatoxin rice contamination TLC principal component analysis

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Cosmic implications of the 12C(n, γ)13C reaction: a nuclear astrophysical perspective

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Chinese Physics C 2024年第2期48卷 171-174页

作者： soumya Saha Department of Physics Bidhan Chandra CollegeRishra31G.T.Road(East)Hooghly-712248India Department of Physics University of Calcutta92Acharya Prafulla Chandra RoadKolkata-700009India

We conducted a comprehensive study of the neutron capture cross section of 12C within the relevant astrophysical energy *** rigorous R-matrix analysis,we determined the Maxwellian-averaged cross section to be 11.98±0.25μb at kT=30 *** result is approximately four times higher than the thermal neutron capture cross section estimated in earlier studies assuming the 1/v *** implications of our findings extend to the region of inhomogeneous Big-Bang models in nuclear astrophysics,where understanding the behaviour of neutron capture cross sections plays a crucial role in elucidating the intricate processes that shaped the early universe.

关键词： reaction cross section R-matrix reaction rates spectroscopic factors

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极端质量比旋近数据分析方法综述

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北京大学学报(自然科学版) 2025年第1期61卷 181-194页

作者：邹晓博 soumya Mohanty 谢群英陈弦罗洪刚刘玉孝韩文标矫佳庚张学昊赵少东郭意扬王瀚之金书竹兰州大学物理科学与技术学院兰州730000 兰州大学理论物理中心甘肃省理论物理重点实验室兰州730000 中国科学院晨兴数学中心北京100190 中国科学院数学与系统科学研究院科学与工程计算国家重点实验室北京100190 University of Texas Rio Grande Valley Brownsville/Texas 78582 北京大学物理学院北京100871 中国科学院上海天文台上海200030 中国科学院大学国际理论物理中心(亚太地区)北京100190

极端质量比旋近EMRI指质量比在10^(4)~10^(7)之间的双星系统,其中小质量天体被捕获后绕大质量黑洞旋近,期间损失的能量以引力波的形式向外辐射。旋近结束前的最后一年估计能产生105个旋近周期,因此可提供丰富的引力波相位演化信息。小... 详细信息

极端质量比旋近EMRI指质量比在10^(4)~10^(7)之间的双星系统,其中小质量天体被捕获后绕大质量黑洞旋近,期间损失的能量以引力波的形式向外辐射。旋近结束前的最后一年估计能产生105个旋近周期,因此可提供丰富的引力波相位演化信息。小质量天体处在大质量黑洞的强引力环境中,运动轨迹能反映大质量黑洞周围的时空结构,其波形可用来限制引力理论和无毛定理等。大质量黑洞一般处在星系中心,星系所处的天文学环境会在波形中留下痕迹。多个波源能给出大黑洞的质量和自旋分布,用于限制宇宙演化和星系演化等。基于上述科学意义,EMRI成为空间引力波计划LISA、太极和天琴的重要观测目标,因此对EMRI的数据分析成为一个重要任务。EMRI波形的高维度和复杂性对数据分析方法要求较高,目前还没有公认的满意答案。首先回顾LISA模拟数据挑战赛中提出的方法和最近的讨论,然后总结EMRI数据分析的难点,并提出改进方法,最后讨论未来研究发展中可能用到的几个线索。

关键词：极端质量比旋近信号探测参数估计频谱法匹配滤波

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Graph Convolutional Network Based Fault Detection and Identification for Low-voltage DC Microgrid

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Journal of Modern Power Systems and Clean Energy 2023年第3期11卷 917-926页

作者： Ambuj Pandey soumya R.Mohanty Department of Electrical Engineering Indian Institute of Technology(BHU)VaranasiUttar PradeshIndia IEEE

This paper presents a novel fault detection and identification method for low-voltage direct current(DC)microgrid with meshed *** proposed method is based on graph convolutional network(GCN),which utilizes the explicit spatial information and measurement data of the network topology to identify a *** has a more substantial feature extraction ability even in the presence of noise and bad *** adjacency matrix for GCN is developed by considering the network topology as an inherent *** bus voltage and line current samples after faults are regarded as the node ***,the DC microgrid model is developed using PSCAD/EMTDC simulation,and fault simulation is carried out by considering different possible events that include environmental and physical *** performance of the proposed method under different conditions is compared with those of different machine learning techniques such as convolutional neural network(CNN),support vector machine(SVM),and fully connected network(FCN).The results reveal that the proposed method is more effective than others at detecting and classifying *** method also possesses better robustness under the presence of noise and bad data.

关键词： DC microgrid graph convolution network fault detection topological information

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Advances in radiotherapy in the treatment of esophageal cancer

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World Journal of Clinical Oncology 2025年第3期16卷 181-186页

作者： Vrushab Rao soumya Singh Bhooshan Zade Department of Cyberknife Radiosurgery and Radiation Oncology Ruby Hall ClinicPune 411001MaharashtraIndia

Recent advancements in radiotherapy for esophageal cancer have significantly improved treatment outcomes and patient quality of *** radiotherapy techniques have been enhanced by the integration of advanced imaging and precision targeting technologies,such as intensity-modulated radiotherapy and proton therapy,which allow for more accurate tumor targeting while minimizing damage to surrounding healthy ***,combining radiotherapy with immunotherapy has shown promising results,leveraging the body’s im-mune response to enhance the effectiveness of cancer *** have also highlighted the benefits of neoadjuvant chemoradiation followed by surgical resection,which has been associated with improved overall survival rates com-pared to radiotherapy *** innovations are paving the way for more effe-ctive and personalized treatment strategies,offering new hope for patients with esophageal cancer.

关键词： Esophageal cancer Radiotherapy Advances Immunotherapy Multi-modality treatment Chemoradiotherapy

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Data-Driven Approaches for Spatio-Temporal Analysis:A Survey of the State-of-the-Arts

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Journal of Computer Science & Technology 2020年第3期35卷 665-696页

作者： Monidipa Das soumya K.Ghosh School of Computer Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore Department of Computer Science and Engineering Indian Institute of Technology KharagpurKharagpur 721302India

With the advancement of telecommunications,sensor networks,crowd sourcing,and remote sensing technology in present days,there has been a tremendous growth in the volume of data having both spatial and temporal *** huge volume of available spatio-temporal(ST)data along with the recent development of machine learning and computational intelligence techniques has incited the current research concerns in developing various data-driven models for extracting useful and interesting patterns,relationships,and knowledge embedded in such large ST *** this survey,we provide a structured and systematic overview of the research on data-driven approaches for spatio-temporal data *** focus is on outlining various state-of-the-art spatio-temporal data mining techniques,and their applications in various *** start with a brief overview of spatio-temporal data and various challenges in analyzing such data,and conclude by listing the current trends and future scopes of research in this multi-disciplinary *** with other relevant surveys,this paper provides a comprehensive coverage of the techniques from both computational/methodological and application *** anticipate that the present survey will help in better understanding various directions in which research has been conducted to explore data-driven modeling for analyzing spatio-temporal data.

关键词： data-driven modeling spatio-temporal data prediction change pattern detection outlier detection hotspot detection partitioning/summarization (tele-)coupling visual analytics

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Design of a Robust Optimal Decentralized PI Controller Based on Nonlinear Constraint Optimization For Level Regulation: An Experimental Study

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IEEE/CAA Journal of Automatica Sinica 2020年第1期7卷 187-199页

作者： soumya Ranjan Mahapatro Bidyadhar Subudhi Sandip Ghosh Department of Electrical Engineering National Institute of Technology RourkelaRourkela 769008India School of Electrical Sciences Indian Institute of TechnologyFarmagudiGoa 403401India Department of Electrical Engineering Indian Institute of TechnologyVaranasi 221005India

This paper presents the development of a new robust optimal decentralized PI controller based on nonlinear optimization for liquid level control in a coupled tank system. The proposed controller maximizes the closed-loop bandwidth for specified gain and phase margins, with constraints on the overshoot ratio to achieve both closed-loop performance and robustness. In the proposed work, a frequency response fitting model reduction technique is initially employed to obtain a first order plus dead time(FOPDT) model of each higher order subsystem. Furthermore, based on the reduced order model, a proposed controller is designed. The stability and performance of the proposed controller are verified by considering multiplicative input and output uncertainties. The performance of the proposed optimal robust decentralized control scheme has been compared with that of a decentralized PI controller. The proposed controller is implemented in real-time on a coupled tank system. From the obtained results,it is shown that the proposed optimal decentralized PI controller exhibits superior control performance to maintain the desired level, for both the nominal as well as the perturbed case as compared to a decentralized PI controller.

关键词： Decentralized control multivariable system process control parameter uncertainty robustness

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Improved energy recovery from dark fermented cane molasses using microbial fuel cells

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Frontiers of Chemical Science and Engineering 2014年第1期8卷 43-54页

作者： soumya Pandit Balachandar G Debabrata Das Department of Biotechnology Indian Institute of Technology Kharagpur West Bengal India

A major limitation associated with fermenta- tive hydrogen production is the low substrate conversion efficiency. This limitation can be overcome by integrating the process with a microbial fuel cell （MFC） which converts the residual energy of the substrate to electricity. Studies were carried out to check the feasibility of this integration. Biohydrogen was produced from the fermen- tation of cane molasses in both batch and continuous modes. A maximum yield of about 8.23 mol Hz/kg CODremoved was observed in the batch process compared to 11.6 mol Hz/kg CODremoved in the continuous process. The spent fermentation media was then used as a substrate in an MFC for electricity generation. The MFC parameters such as the initial anolyte pH, the substrate concentration and the effect ofpre-treatment were studied and optimized to maximize coulombic efficiency. Reductions in COD and total carbohydrates were about 85% and 88% respectively. A power output of 3.02 W/m3 was obtained with an anolyte pH of 7.5 using alkali pre-treated spent media. The results show that integrating a MFC with dark fermentation is a promising way to utilize the substrate energy.

关键词： dark fermentation biohydrogen microbialfuel cell volatile fatty acid anolyte

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