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Exploring Passive Exoskeleton-Induced Changes in Lumbar Muscle Activity

Open Journal of Therapy and Rehabilitation 2023年第4期11卷 149-157页

作者： Ryo Fujitani Hiroko Kawasaki Mika Suzuki Shogo Sakai souma hori Ryoga Muranishi Shinichi Noguchi Takumi Jiroumaru Michio Wachi Kouhei Okuyama Department of Physical Therapy Biwako Professional University of Rehabilitation Higashiomi Japan Department of Physical Therapy Bukkyo University Kyoto Japan

Purpose: The purpose of this study was to evaluate the effect of using a passive exoskeleton on lumbar muscle activity during lifting movements, and to determine whether muscle activity remains altered after exoskeleton removal. This study sought to identify the potential risks and benefits associated with the use of passive exoskeletons for the prevention and treatment of low back pain. Methods: Eighteen healthy adult participants lifted a 10 kg suitcase while wearing a passive exoskeleton. Muscle activity and postures were measured during lifting and before, during, and after exoskeleton use. This study examined whether the reduced muscle activity observed during exoskeleton use persisted after exoskeleton removal. Muscle activity was assessed using electromyography and postures were recorded using reflective markers and a camera. Results: The study found that Lumbar muscle activity decreased significantly (approximately 40%) during exoskeleton use compared to that without exoskeleton use. Importantly, lumbar muscle activity remained low after exoskeleton removal, at levels similar to those observed during exoskeleton use. This suggests that individuals adapted to the exoskeleton support and maintained altered muscle control, even without the exoskeleton. Conclusion: This study demonstrates that passive exoskeletons significantly reduce lumbar muscle activity during lifting tasks, and that this altered muscle control persists after exoskeleton removal. These findings contribute to the understanding of the risks and benefits of passive exoskeletons, potentially aiding their development and informing their use in the prevention and treatment of low back pain.

关键词： Passive Exoskeleton Low Back Pain Muscle Activity Adaptation

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Many Kinds of Reserved Judgement in No-Data Problem

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Applied Mathematics 2024年第1期15卷 1-8页

作者： Houju hori Jr. Nara Community Tsubakikishi Shrine Nara Japan

The reserved judgment can be broadly categorized into three types: Re-Do, Re-Set, and Natural Flowing Case (i.e. step by step in Re-Try). hori et al. constructed the Bayes-Fuzzy Estimation and demonstrated that system theory can be applied to the possibility of Markov processes, and that decision-making approaches can be applied to sequential Bayes estimation. In this paper, we focus on the Natural Flowing Case within reserved judgment. Here, the possibility of oblique (or principal) factor rotation is considered as a part of the tandem fuzzy system that follows step by step for sequential Bayes estimation. Ultimately, we achieve a significant result whereby the expected utility can be calculated automatically without the need to construct a utility function for reserved judgment. There, this utility in Re-Do can be calculated by the prior utility, and that utility in Re-set does not exist by our research in this paper. Finally, we elucidate the relationship between fuzzy system theory and fuzzy decision theory through an applied example of Bayes-Fuzzy theory. Fuzzy estimation can be applied to only normal making decision, but it is impossible to apply abnormal decision problem. Our Vague, specially Type 2 Vague can be applied to abnormal case, too.

关键词： Bayes-Fuzzy Estimation Re-Do Re-Set Indifferent Zone Reserved Judgement

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Report for Type 2 Bayes-Fuzzy Estimation in No-Data Problem

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Applied Mathematics 2024年第1期15卷 46-50页

作者： Houju hori Jr. Kazuhisa Takemura Yukio Matsumoto Nara Cmmunity Tsubakikishi Shrine Nara Japan Department of Psychology Waseda University Tokyo Japan The Institute of Mathematical Statistics Tachikawa Japan

It is well known that the system (1 + 1) can be unequal to 2, because this system has both observation error and system error. Furthermore, we must provide our mustered service within our cool head and warm heart, where two states of nature are existing upon us. Any system is regarded as the two-dimensional variable error model. On the other hand, we consider that the fuzziness is existing in this system. Though we can usually obtain the fuzzy number from the possibility theory, it is not fuzzy but possibility, because the possibility function is as same as the likelihood function, and we can obtain the possibility measure by the maximal likelihood method (i.e. max product method proposed by Dr. Hideo Tanaka). Therefore, Fuzzy is regarded as the only one case according to Vague, which has both some state of nature in this world and another state of nature in the other world. Here, we can consider that Type 1 Vague Event in other world can be obtained by mapping and translating from Type 1 fuzzy Event in this world. We named this estimation as Type 1 Bayes-Fuzzy Estimation. When the Vague Events were abnormal (ex. under War), we need to consider that another world could exist around other world. In this case, we call it Type 2 Bayes-Fuzzy Estimation. Where hori et al. constructed the stochastic different equation upon Type 1 Vague Events, along with the general following probabilistic introduction method from the single regression model, multi-regression model, AR model, Markov (decision) process, to the stochastic different equation. Furthermore, we showed that the system theory approach is Possibility Markov Process, and that the making decision approach is Sequential Bayes Estimation, too. After all, Type 1 Bays-Fuzzy estimation is the special case in Bayes estimation, because the pareto solutions can exist in two stochastic different equations upon Type 2 Vague Events, after we ignore one equation each other (note that this is Type 1 case), we can obtain both its

关键词： Bayes-Fuzzy Estimation Possibility Markov Process Possibility Reserved Judgement

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Inverse relationship between platelet Akt activity and hippocampal atrophy:A pilot case-control study in patients with diabetes mellitus

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World Journal of Clinical Cases 2024年第2期12卷 302-313页

作者： Haruhiko Tokuda Takamitsu hori Daisuke Mizutani Tomoyuki Hioki Kumi Kojima Takashi Onuma Yukiko Enomoto Tomoaki Doi Rie Matsushima-Nishiwaki Shinji Ogura Hiroki Iida Toru Iwama Takashi Sakurai Osamu Kozawa Department of Metabolic Research Research InstituteNational Center for Geriatrics and GerontologyObu 474-8511Japan Department of Clinical Laboratory National Center for Geriatrics and GerontologyObu 474-8511Japan Department of Pharmacology Gifu University Graduate School of MedicineGifu 501-1194Japan Department of Neurosurgery Gifu University Graduate School of MedicineGifu 501-1194Japan Department of Dermatology Central Japan International Medical CenterMinokamo 505-8510Japan Department of Anesthesiology and Pain Medicine Gifu University Graduate School of MedicineGifu 501-1194Japan Department of Emergency Medicine Faculty of MedicineUniversity of ToyamaToyama 930-0194Japan Department of Emergency and Disaster Medicine Gifu University Graduate School of MedicineGifu 501-1194Japan Research Institute National Center for Geriatrics and GerontologyObu 474-8511Japan

BACKGROUND Akt plays diverse roles in *** is involved in the pathogenesis of type 2 diabetes mellitus(T2DM),which is caused by insulin *** also plays a vital role in human platelet ***,the hippocampus is closely associated with memory and learning,and a decrease in hippocampal volume is reportedly associated with an insulin-resistant phenotype in T2DM patients without *** To investigate the relationship between Akt phosphorylation in unstimulated platelets and the hippocampal volume in T2DM *** Platelet-rich plasma(PRP)was prepared from the venous blood of patients with T2DM or age-matched *** pellet lysate of the centrifuged PRP was subjected to western blotting to analyse the phosphorylation of Akt,p38 mitogen-activated protein(MAP)kinase and glyceraldehyde 3-phosphate dehydrogenase(GAPDH).Phosphorylation levels were quantified by densitometric *** volume was analysed using a voxel-based specific regional analysis system for Alzheimer’s disease on magnetic resonance imaging,which proposes the Z-score as a parameter that reflects hippocampal *** The levels of phosphorylated Akt corrected with phosphorylated p38 MAP kinase were inversely correlated with the Z-scores in the T2DM subjects,whereas the levels of phosphorylated Akt corrected with GAPDH were ***,this relationship was not observed in the control *** These results suggest that an inverse relationship may exist between platelet Akt activation and hippocampal atrophy in T2DM *** findings provide insight into the molecular mechanisms underlying T2DM hippocampal atrophy.

关键词： Akt Platelet Hippocampal atrophy Magnetic resonance imaging Diabetes mellitus

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Phytochemical Analysis and Antimicrobial Activity of Lawsonia inermis Leaf Extracts from Burkina Faso

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American Journal of Plant Sciences 2024年第7期15卷 552-576页

作者： Ollo Youl soumaïla Konaté Ernest N. Sombié Rainatou Boly Boukaré Kaboré Moumouni Koala Arouna Zoungrana Saybou Savadogo Christian Marc Tahita Innocent Valea Halidou Tinto Adama Hilou Maminata Traoré-Coulibaly Laboratoire de Biochimie et de Chimie Applique (LABIOCA) Universit de Ouagadougou Ouagadougou Burkina Faso Agence Nationale Pour la Scurit Sanitaire de lEnvironnement de lAlimentation du Travail et des Produits de Sant (ANSSEAT) Ouagadougou Burkina Faso Laboratoire de Recherche-Dveloppement de Phytomdicaments et Mdicaments (L-RD/PM) Institut de Recherche en Sciences de la Sant (IRSS-CNRST) Ouagadougou Burkina Faso Laboratoire de Chimie Organique et de Physique Applique (LCOPA) cole Doctorale Sciences et Technologie Universit Joseph KI-ZERBO Ouagadougou Burkina Faso Laboratoire Sciences de la Vie et de la Terre (LASVT) cole Doctorale Sciences et Technologie Universit Norbert ZONGO Koudougou Burkina Faso Unit de Recherche Clinique de Nanoro Institut de Recherche en Sciences de la Sant (IRSS-CNRST) Nanoro Burkina Faso

Lawsonia inermis is a hairless plant growing in various regions of North Africa, the Indian subcontinent, and the Middle East. It possesses many medicinal attributes, including curative properties against infectious dermatoses. This study was carried out to evaluate the phytochemical profile of the crude ethanolic extract of the plant leaves and its fractions as well as their antimicrobial activities. The phytochemical profile was performed using high-performance thin-layer chromatography (HPTLC), gas chromatography-mass spectrometry (GC-MS), and high-performance liquid chromatography (HPLC). Additionally, the phenolic and flavonoid contents were determined using the Folin-Ciocalteu spectrophotometric and the aluminum trichloride methods. Antimicrobial activity was tested using disc diffusion and microdilution methods. The presence of flavonoids, tannins, sterols, and triterpenes was revealed. GC-MS detected twelve compounds main compounds consisting of saturated and unsaturated fatty acids and phenolic and terpenoid compounds among twenty-seven components. HPLC also detected high contents of phenolic acids and flavonoids. The most abundant triterpene and sterols were ursolic acid (around 43.14 g/100g DW, 13.9 g/100g dry weight (DW), and 0.68 g/100g DW) in the crude ethanolic extract of leaves (FeLi), hexane fraction (FHLi) and dichloromethane fraction (FDLi), respectively and, β-sitosterol in FeLi (56.7 mg/100g DW), FHLi (10.55 g/100g DW), FDLi (106.1 mg/100g DW) and butanol fraction (FBLi) (357.4 mg/100g DW). Among the flavonoids, rutin = 3.24 g/100g and quercetin = 0.63 g/100g in the ethanolic extract, rutin = 15.73 g/100g in the dichloromethane fraction, and rutin = 0.23 g/100g) in the aqueous fraction;and among phenolic compounds, caffeic acid (37.65 g/100g DW) and vanillic acid (22.70 g/100g DW) were the most important in the ethyl acetate fraction (FAeLi). All organic fractions exhibited interesting antibacterial and antifungal activities against the tested s

关键词： Lawsonia inermis Phytochemical Profile HPLC GC-MS Analysis Antimicrobial Activity

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执迷于《欢愉》的人:戈达尔与马克斯·奥菲尔斯

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电影艺术 2024年第3期 36-40页

作者： [日]堀润之龚金浪(译) 应雄(校译) 不详江西师范大学新闻与传播学院北海道大学文学院

马克斯·奥菲尔斯的《欢愉》在戈达尔的电影生涯中有着特别的意义。该片上映时,巴赞批评影片过于“奢华”,其“巴洛克风格”与莫泊桑原著故事格格不入。而彼时的新生代影评人特吕弗、戈达尔等人则以全新的评判标准对此观点提出质疑。戈... 详细信息

马克斯·奥菲尔斯的《欢愉》在戈达尔的电影生涯中有着特别的意义。该片上映时,巴赞批评影片过于“奢华”,其“巴洛克风格”与莫泊桑原著故事格格不入。而彼时的新生代影评人特吕弗、戈达尔等人则以全新的评判标准对此观点提出质疑。戈达尔认为,奥菲尔斯精湛的摄影机运动,绝非“多余的奢华”,而是如同“素描”一般在曲线结束时自然显现内容的形式,其本身就是“另一种内容”,他以《影像之书》结尾处对《欢愉》的引用,完成了对巴赞的反驳。

关键词：马克斯·奥菲尔斯巴赞戈达尔奢华素描

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Digestive Surgical Emergencies at the “Mother Child”Hospital Center Luxembourg in Mali

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Surgical Science 2024年第5期15卷 299-310页

作者： Cheickna Tounkara Amara Coulibaly Yaya Ongoiba Aboubakrine Sylla Abdoul Karim Simaga Bréhima B. Coulibaly Aminata Dabo Souleymane Dembele Samake Hamidou Sidiki Keita Sékou Bréhima Koumare soumaïla Keita Bakary Tientigui Dembele Zimogo Zié Sanogo Djibril Sangare Department of General Surgery and Anesthesia-Resuscitation of the “ Mother Child&#8221 Hospital Center Luxembourg Bamako Mali Social Health Service of the Armed Forces of Mali Bamako Mali Department of General Surgery “ A&#8221 and Cardiovascular of Point G University Hospital Bamako Mali Department of General Surgery of CHU Gabriel TOURE Bamako Mali

Digestive surgical emergencies concern all patients admitted urgently, for whom a decision for surgical intervention may be necessary within 24 hours. They are on guard duty day and night. To carry out this work, we set ourselves the objectives of: 1) Studying digestive surgical emergencies in the general surgery department of the “Mother Child” Le Luxembourg hospital in Bamako, Mali;2) Determine the frequency of digestive surgical emergencies, 3) Describe the clinical and therapeutic aspects, and 4) Analyze the results of treatment. From November 1, 2022 to October 31, 2023, the general surgery department of the “Mother Child” Luxembourg Hospital Center in Bamako, Mali, carried out 139 digestive surgical emergencies whose files were usable;75 men and 64 women, a sex ratio of 1.2. The 20 - 40 years old age group was the most represented, at 40.29%. The average age was 39 years;the extremes 16 years and 93 years with a standard deviation of 21.65 years. The reference concerned 51.08% of our patients. Abdominal pain was the main reason for consultation (100% of cases). In the majority of cases, the physical examination made it possible to make the diagnosis. Faced with certain clinical cases, we requested ultrasound (109/139), ASP (46/139) and CT (15/139). The main etiology was acute appendicitis with 42.45% of cases. The frequency of digestive surgical emergencies was 10.71% of all activities in the general surgery department of the “Mère Enfant” Le Luxembourg hospital center in Bamako. All our patients were seen in consultation by an anesthesiologist before entering the operating room. The surgical consequences were complicated in 11.51% of cases with 7.91% deaths. Surgical site infections accounted for 12.5% of postoperative complications. Eleven deaths were noted, representing 68.75% of complications and 7.91% of our sample. Acute peritonitis was the cause of death in 100% of cases. The average cost of care was 329,000 FCFA.

关键词： Emergency Digestive Surgery Post-Operative Complication

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Molecular Diagnosis of Sexual Differentiation Disorders in Burkina Faso

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Journal of Biosciences and Medicines 2024年第3期12卷 1-15页

作者： Bazie Bapio Valérie Elvira Jean Télesphore Sawadogo soumaïla Zohoncon Théodora Mahoukèdè Tall Ahmadou Bado Prosper Soubeiga Serge Théophile Ouattara Moussa Sorgho Abel Kiendrebeogo Touwendpoulimdé Isabelle Yonli Albert Theophane Djigma Florencia Millogo/Traore Timongo Françoise Danielle Simpore Jacques Centre National de la Recherche Scientifique et Technologique (CNRST) Institut de Recherche en Sciences de la Santé (IRSS) Ouagadougou Burkina Faso Université Joseph KI-ZERBO Unité de Formation en Sciences de la Vie et de la Terre Laboratoire de Biologie Moléculaire et de Génétique (LABIOGENE) Ouagadougou Burkina Faso Centre de Recherche Biomoléculaire Pietro Annigonie (CERBA) Ouagadougou Burkina Faso Centre Hospitalier Universitaire Régional de Ouahigouya Ouagadougou Burkina Faso Centre Hospitalier Universitaire Yalgado Ouedraogo Université Joseph Ki-Zerbo Ouagadougou Burkina Faso

Sex development anomalies represent a group of congenital pathologies in which chromosomal, gonadal and anatomical sex differentiation is atypical. The aim of our study was to use molecular biology techniques to elucidate sex in cases of anomalies of sexual differentiation in Burkina Faso. This cross-sectional study took place from March 2023 to June 2023. Oral and blood samples were collected respectively using sterile swabs and stored on Swab Kits and NUCLEIcardTM (https://***/product-ranges/nucleic-card/) were used to determine gonosome profiles. Extraction was carried out using the DNA Swap solution Kit and the DNA IQ System Kit, and a PowerPlex? 21 kit (Promega) for amplification. The Applied Biosystems 9700 thermal cycler was used for PCR followed by 36 cm capillary electrophoresis in the Applied Biosystems 3130 prism sequencer. Sequence files were analyzed using GeneMapper IDX v. 3.2 software. Seven (07) patients were registered during the study period. There were 4 cases of XX DSD or 46, XX DSD and 3 cases of XY DSD or 46, XY DSD. The median age of our patients was 16 years. Civilian sex was male in 4 cases and female in 3. The most frequent reason for consultation was micropenis in 3 cases, followed by primary amenorrhea and sex ambiguity. There were 03 cases of discrepancy between genetic sex and civil sex. The accessibility of molecular diagnosis is little known to clinicians. XX DSDs or 46, XX DSDs were the most frequent (4/7) in our study. The problem facing this situation is early diagnosis to help prevent complications in Burkina Faso.

关键词： Gonosome DSD Abnormal Sexual Development Burkina Faso

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Technical aspects in pancreaticoduodenectomy and therapeutic strategies for pancreatic cancer:History,current status,and future perspectives

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Hepatobiliary & Pancreatic Diseases International 2022年第6期21卷 600-602页

作者： Tomohide hori Daiki Yasukawa Department of Surgery Shiga General HospitalMoriyama 524-8524Japan Department of Surgery Shiga University of Medical ScienceOtsu 520-2192Japan

The incidence of pancreatic cancer(PC)has increased,and in-vasive ductal adenocarcinoma is the most common among PC pa-tients[1].Even in patients who receive radical treatments,namely chemotherapy and surgery,the five-year survival is only 2%-9%[1].Currently,many physicians recognize that further developments in multidisciplinary therapy are crucial to overcome PC[1].

关键词： cancer chemotherapy surgery

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Optimization of a Solar Chimney with a horizontal Absorber for Building Ventilation:A Case Study

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Fluid Dynamics & Materials Processing 2023年第4期19卷 901-910页

作者： El Hadji I Cisse Baye Alioune Ndiogou soumaïla Tigampo Ababacar Thiam DorothéAzilinon (L3EPI)Laboratory of ESP-UCAD DakarSenegal Center for Energy Research and Sustainability DAUSTDakarSenegal Universiy Alioune Diop of Bambey BambeySenegal

A study is conducted to optimize the geometry of a solar chimney equipped with a horizontal absorber in order to improve its performances in relation to the provision of *** problem is tackled through numerical solution of the governing equations for mass,momentum and energy in their complete three-dimensional and unsteady *** numerical framework also includes a turbulence model(k-ε)and a radiant heat transfer(DO)***,a Multi-Objective Genetic Algorithm(MOGA)is employed to derive the optimal configuration of the considered solar *** is shown that an air velocity of 0.2 m/s can be *** value is the minimum allowed air velocity according to the ASHRAE’s(American Society of Heating,Refrigerating and Air-Conditioning Engineers)adaptive comfort approach.

关键词： Natural ventilation adaptative comfort solar chimney fluent MOGA

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