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Low fermentable oligosaccharides, disaccharides,monosaccharides, and polyols diet in children

World Journal of Clinical Cases 2019年第18期7卷 2666-2674页

作者： Ioana Fodor sorin claudiu man Dan L Dumitrascu 3^rd Pediatric Department Iuliu Hatieganu University of Medicine and PharmacyCluj-Napoca 400006Romania 2^nd Medical Department Iuliu Hatieganu University of Medicine and PharmacyCluj-Napoca 400006Romania

Irritable bowel syndrome (IBS) is a lifelong condition with a high prevalence among children and adults. As the diet is a frequent factor that triggers the symptoms, it has been assumed that by avoiding the consumption of fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP), the symptoms might be improved. Therefore, in the past decade, low FODMAP diet has been intensively investigated in the management of IBS. The capacity of FODMAPs to trigger the symptoms in patients with IBS was related to the stimulation of mechanoreceptors in the small and large intestine. This stimulation appears as a response to a combination of increased luminal water (the osmotic effect) and the release of gases (carbon dioxide and hydrogen) due to the fermentation of oligosaccharides and malabsorption of fructose, lactose and polyols. Numerous studies have been published regarding the efficacy of a low FODMAP diet compared to a traditional diet in releasing the IBS symptoms in adults, but there are only a few studies in the juvenile population. The aim of this review is to analyze the current data on both low FODMAP diet in children with IBS and the effects on their nutritional status and physiological development, given the fact that it is a restrictive diet.

关键词： Low fermentable oligosaccharides Disaccharides Monosaccharides Polyols Diet Children Irritable bowel syndrome Symptom

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Acute Paraplegia Due to <i>Salmonella brandenburg</i>Spondylodiscitis: Case Report

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Open Journal of Modern Neurosurgery 2019年第3期9卷 327-337页

作者： claudiu Popa Maguette Mbaye Mbaye Thioub Tanguy Riem Benjamin Daumas-Duport Nathalie Asseray Roger Robert Department of Neurosurgery CHU Saint Etienne Saint Etienne France Department of Neurosurgery CHNU Fann Dakar Sénégal Department of Neurosurgery CHU Nantes Nantes France Department of Neuroradiology CHU Nantes Nantes France Department of Infectious Diseases CHU Nantes Nantes France

The authors present the case of a 48-year-old man admitted for acute onset of paraplegia in a patient suffering from backaches for 1 week. The rapidly progressive motor disturbances had been evolving for approximately 12 hours. The entire spinal MRI showed an epidural mass at T4-T6 associated with extensive lesions of spondylodiscitis and a T7-T8 vertebral body loss of height. A large six-level laminectomy was performed. A tumoral etiology couldn’t be entirely excluded intraoperatively so that no fusion has been done at that time. The pathological exam revealed acute inflammatory lesions with no argument in favor of a tumoral process. Bacteriological exam of the pathological specimen and stools cultures were positive for Salmonella brandenburg. An episode of gastroenteritis after the ingestion of a pizza has been evoked. The antibiotic medication was prescribed for 12 weeks. Postoperative evolution was favorable with a possible march between bars 6 weeks after. The authors emphasize the pseudo-tumoral presentation in an immunocompetent patient, the lack of complications and the post-ingestion mechanism.

关键词： Spondylodiscitis Spinal Epidural Abscess Paraplegia Salmonella brandenburg Post-Ingestion Immunocompetent

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