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作者： M soriba naby camara 华中科技大学

学位级别：硕士

目的研究中国人群中慢性胰腺炎的病因、病理特点，治疗和预后。方法收集2008年1月至2011年12月在武汉协和医院142例慢性胰腺炎患者。对这些患者的病因、病理、治疗和预后进行回顾性分析。结果数据显示，大多数患者的病因是慢性... 详细信息

目的研究中国人群中慢性胰腺炎的病因、病理特点，治疗和预后。方法收集2008年1月至2011年12月在武汉协和医院142例慢性胰腺炎患者。对这些患者的病因、病理、治疗和预后进行回顾性分析。结果数据显示，大多数患者的病因是慢性阻塞性胰腺炎，72（50.70％），而其他酒精性慢性胰腺炎，20（14.08％），自身免疫性慢性胰腺炎（9.86％）和特发性慢性胰腺炎36（25.35％）。炎性包块平均直径为3.8±3.3厘米（范围从2.8厘米到4.8厘米）。27例（7例在术中冰冻切片发现有胰脏癌），CA19-9显着增加;90例患者进行了手术治疗，34例经内镜括约肌切开术和14例保守;42例行保留十二指肠的胰头全切术。25例患者实施了保留十二指肠的胰头次全切除术，7例进行标准胰十二指肠切除术，囊空肠吻合术18例，2例行胰空肠吻合。术后无病人死亡。胰瘘、腹腔内出血、伤口裂口、胆漏和十二指肠瘘手术并发症的发生例数分别为3例，4例，2例，2和1例。有76例患者疼痛缓解，17例患者疼痛复发。94例患者手术后体重增加。结论胰管梗阻仍然是中国人口慢性胰腺炎最常见的原因。保留十二指肠的胰头切除术是慢性胰腺炎合并炎性包块的适宜治疗方式。在慢性胰腺炎CA19-9增高是胰腺癌的高危因素。

关键词：慢性胰腺炎病因病理特点治疗预后中国人

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High Risk Factors of Pancreatic Carcinoma

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2016年第3期36卷 295-304页

作者： soriba naby camara 殷涛杨明李响龚琼周静赵刚杨智勇 Tajoo Aroun Martin Kuete Sonam Ramdany Alpha Kabinet camara Aissatou Taran Diallo 冯珍宁辛熊炯新陶京钦琪周伟崔静黄敏郭尧勾善淼王博刘涛 Ohoya Etsaka Terence Olivier Tenin Conde Mohamed Cisse Aboubacar Sidiki Magassouba Sneha Ballah naby Laye Moussa Keita Ibrahima Sory Souare Aboubacar Toure Sadamoudou Traore Abdoulaye Korse Balde Namory Keita naby Daouda camara Dusabe Emmanuel 吴河水王春友 Department of General Surgery Pancreatic disease InstituteUnion Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Breast and.Thyroid Surgery Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Planning Family and Reproductive Institute Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of General Medicine Sir Seewoosagur Ramgoolam National Hospital of PamplemoussesMauritius 21017Mauritius Department of Thoracic Surgery Friendship Hospital Sino-Guinea of Kipe Department of General Surgery National Hospital of Ignace DeenConakry 1147Guinea Department of Gastroenterology and Hepatology Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Nephrology Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Dermatology Friendship Hospital Sino-Guinea of Kipe Department of Internal Medicine Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Biochemistry University Gamal Abdel Nasser of ConakryConakryl147Guinea Department of Neurosurgery Friendship Hospital Sino-Guinea of Kipe Department of Medical Imaging Good Shepherd Medical CenterThe University of TexasLongview 75601USA Department of Visceral Surgery National Hospital of Donka Department of Gynecology and Obstetrics National Hospital of Donka Department of Stomatology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Over the past decades, cancer has become one of the toughest challenges for health professionals. The epidemiologists are increasingly directing their research efforts on various malignant tumor worldwide. Of note, incidence of cancers is on the rise more quickly in developed countries. Indeed, great endeavors have to be made in the control of the life-threatening disease. As we know it, pancreatic cancer（PC） is a malignant disease with the worst prognosis. While little is known about the etiology of the PC and measures to prevent the condition, so far, a number of risk factors have been identified. Genetic factors, pre-malignant lesions, predisposing diseases and exogenous factors have been found to be linked to PC. Genetic susceptibility was observed in 10% of PC cases, including inherited PC syndromes and familial PC. However, in the remaining 90%, their PC might be caused by genetic factors in combination with environmental factors. Nonetheless, the exact mechanism of the two kinds of factors, endogenous and exogenous, working together to cause PC remains poorly understood. The fact that most pancreatic neoplasms are diagnosed at an incurable stage of the disease highlights the need to identify risk factors and to understand their contribution to carcinogenesis. This article reviews the high risk factors contributing to the development of PC, to provide information for clinicians and epidemiologists.

关键词： high risk factors pancreatic cancer treatment epidemiology pathogenesis etiology

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Etiology, Pathology, Management and Prognosis of Chronic Pancreatitis in Chinese Population: A Retrospective Study

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2015年第3期35卷 384-389页

作者： soriba naby camara Sonam Ramdany 赵刚勾善淼熊炯炘杨智勇殷涛杨明 Oumar Taibata Balde Ahmed Boubacar Barry Seid.Adji 李想金岩吴河水王春友 Department of General Surgery Pancreatic Center Union Hospital Tongji Medical College Huazhong University of Science and Technology Department of General Surgery National Hospital of Donka Department of Gastroenterology Pancreatic Center Union Hospital Tongji Medical College Huazhong University of Science and Technology

The purpose of this study was to investigate the etiology, pathological characteristics, management and prognosis of chronic pancreatitis in the Chinese population. The clinical data of 142 patients with chronic pancreatitis were retrospectively studied. All patients were of Chinese nationality and hospitalized from January 2008 to December 2011. Their ages ranged from 14 to 76 years, with a mean of 43 years. Of 142 patients, there were 72 cases of obstructive chronic pancreatitis（50.70%）, 19 cases of alcoholic chronic pancreatitis（13.38%）, 14 cases of autoimmune pancreatitis（9.86%） and 37 cases of undetermined etiology（26.06%）. Pathologically, the average inflammatory mass diameter was 3.8±3.3 cm, biliary obstruction occurred in 36 cases, gall stones in 70 cases, calcification in 88 cases, ductal dilatation in 61 cases, side branch dilatation in 32 cases, ductal irregularity in 10 cases, lymphocytic inflammation in 23 cases, obliterative phlebitis in 14 cases, extra pancreatic lesion in 19 cases and fibrosis in 142 cases. Location of pancreatic lesion in the region of head（n=97）, neck（n=16）, body（n=12）, tail（n=15） and whole pancreas（n=2） influenced the choice of surgical procedures. Ninety-four patients（66.20%） received surgical treatment and 33.80% received other treatments. After operation, 80.85% of 94 patients experienced decreased pain, and 8.51% of 94 showed recovery of endocrine function but with a complication rate of 12.77%. All the operations were performed successfully. According to the pain scale of European Organization for Research and Treatment of Cancer（QLQ-C30） a decrease from 76±22 to 14±18 was observed. Etiology, pathological characteristics, management and prognosis of chronic pancreatitis in the Chinese population vary from others.

关键词： chronic-pancreatitis etiology pathological characteristics management prognosis Chinese population

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Post-Traumatic Pyothorax: Epidemiology, Management and Prognosis in the Thoracic Surgery Department of the Donka National Hospital

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Open Journal of Thoracic Surgery 2021年第4期11卷 83-88页

作者： camara Alpha Kabinet camara soriba naby Balde Oumar Taibata Diallo Amadou Sarah camara Mama Aissata Magassouba Aboubacar Sidiki Balde Abdoulaye Korse Toure Aboubacar Diallo Aissatou Taran Diallo Biro Department of Thoracic Surgery Donka National Hospital Conakry Guinea Faculty of Sciences and Technic of Health Gamal Abdel Nasser University of Conakry Conakry Guinea Department of Visceral Surgery Friendship Hospital Sino Guinean Conakry Guinea Department of Visceral Surgery Donka National Hospital Conakry Guinea Department of General Surgery Ignace Denn National Hospital Conakry Guinea

Pyothoraxes, also called thoracic empyemas, are defined by the presence between the two layers of the pleura, of a frankly purulent liquid, or of a shady or clear liquid but containing a majority of altered polynuclear cells with germs direct examination. They are said to be traumatic when they follow a thoracic trauma whatever the mechanism;usually a pre-existing post-traumatic pleural effusion. The general objective of this study was to help identify the epidemiological and prognostic factors in the management of post-traumatic pyothorax in the Thoracic Surgery Department of the Donka National Hospital. Methodology: This was a descriptive retrospective study covering a period of 2.5 years from 01/06/2016 to 31/12/2018 carried out in the Thoracic Surgery Department of the Donka National Hospital. Results: During the study period, 17 cases of post-traumatic pyothorax were observed among the 288 files of admitted and hospitalized patients. In the course of this study, a rate was 5.90%. The most affected age group was 1 to 5 years old. The male sex was in the majority (76.5%). The most common occurrence was the fall, i.e. 41.2%. 47% of patients consult after 60 days. Chest pain and dyspnea were the main symptoms during our study (82.3%). Antibiotics and analgesics dominated the medical treatment used in 100% of the cases and pleural drainage was the first line surgical treatment practiced in 88.2% of the cases. The prognosis is favorable without sequelae in 52.9% of cases with an average hospital stay

关键词： Pyothorax Trauma Epidemiology Management Prognosis Surgery Donka

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