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World Journal of Gastroenterology 2004年第19期10卷 2785-2790页

作者： I-Shyan Sheen Kuo-Shyang Jeng Po-Chuan Wang Shou-Chuan Shih Wen-Hsing Chang horng-Yuan Wang Chung-Chu Chen Li-Rung Shyung Division of Hepatogastroenterology Chang Gung Memorial HospitalTaipeiTaiwanChina Departments of Surgery Mackay Memorial HospitalTaipeiTaiwanChina Mackay Junior School of NursingTaipeiTaiwanChina M.D.F.A.C.S. Department of Internal Medicine Mackay Memorial HospitalTaipeiTaiwanChina

AIM: To investigate the prognostic value of the expression of connexin (Cx) 26, 32 and 43 messenger RNA (mRNA) in hepatocellular carcinoma (HCC) tissues. METHODS: Using a reverse-transcriptase polymerase chain reaction (RT-PCR), Cx 26, Cx 32 and Cx 43 mRNAs were determined in the liver tissues of 15 controls and in HCC tissues of 25 patients undergoing curative hepatic resection. The patients were followed up ***: Cx 26 and Cx 32 mRNAs were significantly lower in HCC tissues compared with controls (both P<0.01). By multivariate analysis, a lower level of Cx 26 and Cx 32 mRNA correlated significantly with a risk of HCC recurrence (P = 0.033) and recurrence-related mortality (P = 0.031,P= 0.031). Cx 43 mRNA was higher in HCC tissues compared with controls but did not correlate with postoperative recurrence or recurrence-related mortality. Other significant predictors of HCC recurrence included cellular dedifferentiation (P = 0.033), less encapsulation (P = 0.050), vascular permeation (P= 0.046), and daughter nodules (P= 0.046). Significant variables related to recurrence-related mortality consisted of cell dedifferentiation (P = 0.031), vascular permeation (P = 0.048), and daughter nodules (P = 0.048).The levels of Cx 26 and Cx 32 mRNAs correlated significantly with cell differentiation (P= 0.031). CONCLUSION: A low expression of Cx 26 and Cx 32 mRNAs in HCC tissues is predictive of postoperative recurrence of HCCs.

关键词：缺口联合基因接合素肝细胞癌肿瘤 mRNA HCC RT-PCR

Anticandidal potential of stem bark extract from Schima superba and its compound identification

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Anticandidal potential of stem bark extract from Schima supe...

Fields奖获奖入Cedric Villani的工作

中国化学会第十二届全国天然有机化学学术会议

作者： Chun Wu Hong-Tan Wu Qing Wang Guey-horng Wang Xue Yi Yu-Pei Chen Guang-Xiong Zhou Xiamen Key Laboratory of Traditional Chinese Medicine Bio-engineering Xiamen Medical College Research Center of Natural Cosmeceuticals Engineering Xiamen Medical College Application Technique Engineering Center of Natural Cosmeceuticals College of Fuijan ProvinceXiamen Medical College Key Laboratory of Functional and Clinical Translational Medicine Fujian Province UniversityXiamen Medical College Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research College of PharmacyJinan University

Plant-derived extracts were a promising source of new drug and some had the potentially antifungal *** this study,the stem bark extract from Schima superba,namely SSE,was used to explore the anticandidal *** SSE possessed high polyphenols and saponins with 256.6 and 357.8 μg/mg,*** addition,a significantly clear zone against Candida albicans was observed using disc dilution *** half inhibitory concentration of SSE was determined at a concentration of 415.2 μg/mL.A transcriptomics analysis in *** treated with the SSE of the different doses was conducted using *** average of 6,068 genes and20,842,500 clean reads from each sample were *** these samples,1,680 and 1,956 genes were differentially expressed genes(DEGs) as SSE treatment of 0.2 and 0.4 mg/mL,*** genes responsible for up-regulation and down-regulation involved in chitin degradation,ergosterol biosynthesis,and multidrug resistance were *** changes in gene expression associated with the composition of cell wall and membrane indeed caused the arrest of *** *** result can be reflected in the irregular twisted morphology of the ruptured cell using scanning electron microscope ***,the major compound purified from the SSE was identified as sasanquasaponin Ⅲ by ESI-MS and NMR analysis

关键词： Schima superba Candida albicans saponins RNA-seq sasanquasaponin Ⅲ

来源： cnki会议评论

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数学译林 2011年第3期30卷 193-199页

作者： horng-Tzer Yau（姚鸿泽）李天虹（译）陈国璋（校）

1．介绍Cedric Villan工作的出发点要回到19世纪由***（卡诺）和***（克劳休斯）引进的熵（entropy）．在那个时候，熵是个模糊的概念，它的严格定义一直等到***（玻尔兹曼）的奠基性工作之后才出现，玻尔兹曼引进了非平衡态的统计物理... 详细信息

1．介绍Cedric Villan工作的出发点要回到19世纪由***（卡诺）和***（克劳休斯）引进的熵（entropy）．在那个时候，熵是个模糊的概念，它的严格定义一直等到***（玻尔兹曼）的奠基性工作之后才出现，玻尔兹曼引进了非平衡态的统计物理和著名的H泛函．

关键词： Boltzmann 统计物理非平衡态玻尔泛函熵

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雪山隧道空气温度评估

隧道建设 2007年第S2期27卷 577-581页

作者：李宏彻国道新建工程局

位于亚热带的台湾长公路隧道的空气温升问题颇值重视,雪山隧道初期只通行小型车,空气温度最高约40℃,就已成媒体的焦点,对即将通行大客车提出质疑。利用现场监测温度分析隧道壁的吸热能力,并据以推估下阶段之可能温升,发现若未启动通风... 详细信息

位于亚热带的台湾长公路隧道的空气温升问题颇值重视,雪山隧道初期只通行小型车,空气温度最高约40℃,就已成媒体的焦点,对即将通行大客车提出质疑。利用现场监测温度分析隧道壁的吸热能力,并据以推估下阶段之可能温升,发现若未启动通风设施时确会高达51.5℃;但只要启动风机应可控制在40℃之下。

关键词：长隧道温升现场监测

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Adhesive small bowel obstruction: How long can patients tolerate conservative treatment?

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World Journal of Gastroenterology 2003年第3期9卷 603-605页

作者： Shou-Chuan Shih Kuo-Shyang Jeng Shee-Chan Lin Chin-Roa Kao Sun-Yen Chou horng-Yuan Wang Wen-Hsiung Chang Cheng-Hsin Chu Tsang-En Wang General Surgery Section Department of SurgeryMackay Memorial HospitalTaipeiTaiwan China Mackay Junior School of NursingTaipeiTaiwanChina General Surgery Section Department of SurgeryMackay Memorial HospitalTaipeiTaiwan China Gastroenterology Section Department of Internal MedicineMackay Memorial HospitalTaipeiTaiwan

AIM: To evaluate how long patients with small bowel obstruction caused by postoperative adhesions can tolerate conservative ***: The records of patients with small bowel obstruction due to postoperative adhesions were retrospectively reviewed. Data collected included the number of admissions, type of management for each admission,duration of conservative treatment, number of repeat laparotomies, and operative ***: One hundred fifty-five patients with this condition from January 1999 to December 2001, for a total of 293 admissions were enrolled in this study. Medical treatment alone was given in 220 admissions, and repeat laparotomy was performed in 73 admissions. The period of observation in patients managed medically ranged from 2 to 12 days (average: 6.9 days), while for those who underwent surgery,the range was 1 to 14 days (average 5.4 days). At surgery,adhesions were the only finding in 46 cases, while there were intestinal complications in 27, or 9.2 % of all 293admissions. Fever and leukocytosis greater than 15 000/mm3were prediction of intestinal ***: With closely monitoring, most patients with small bowel obstruction due to postoperative adhesions could tolerate supportive treatment and recover well averagely within 1 week, although some patients require more than 10 days of observation.

关键词：粘连性小肠梗阻保守疗法耐受性术后并发症临床研究

一类三角多项式对某些多元周期函数的逼近性质(Натансон定理的拓广及其他)

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吉林大学自然科学学报 1963年第3期 173-179页

作者：王仁宏

最近,徐利治与作者在论文[1]的附录中曾引进了一类新的多元 Vallée-Poussin型奇异积分（多变量三角多项式）其中λn 由关系式 Vn[1;x]≡1所确定,而 t≡（t1,…,tk）,x≡（x1,…,xk）表 k 维欧氏空间 Ek 中的点向量,dt≡dt1,…,dtk。并... 详细信息

最近,徐利治与作者在论文[1]的附录中曾引进了一类新的多元 Vallée-Poussin型奇异积分（多变量三角多项式）其中λn 由关系式 Vn[1;x]≡1所确定,而 t≡（t1,…,tk）,x≡（x1,…,xk）表 k 维欧氏空间 Ek 中的点向量,dt≡dt1,…,dtk。并且对于这种奇异积分的逼近性质作了一些

关键词：定理拓广三角多项式

一种基于序列到序列时空注意力学习的交通流预测模型

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计算机研究与发展 2020年第8期57卷 1715-1728页

作者：杜圣东李天瑞杨燕王浩谢鹏洪西进西南交通大学信息科学与技术学院成都610031 台湾科技大学计算机科学与信息工程系中国台北10607

城市交通流预测是研究交通时空序列数据的动态演化并预测未来交通情况的关键技术,对于智能交通预警及管理决策来讲至关重要.但是有效的交通流建模非常具有挑战性,因为它受到很多复杂因素的影响,例如交通网络的时空依赖性和序列突变性等... 详细信息

城市交通流预测是研究交通时空序列数据的动态演化并预测未来交通情况的关键技术,对于智能交通预警及管理决策来讲至关重要.但是有效的交通流建模非常具有挑战性,因为它受到很多复杂因素的影响,例如交通网络的时空依赖性和序列突变性等问题.一些研究工作将卷积神经网络(convolutional neural networks, CNN)或循环神经网络(recurrent neural networks, RNN)用于交通流量预测建模.但是,直接使用经典的深度学习模型难以有效捕获与交通流相关的多通道多变量序列数据中的隐含时空依赖性特征.针对上述问题,提出了一种新的序列到序列时空注意力深度学习框架(spatial-temporal attention traffic forecasting, STATF)来处理城市交通流建模任务,它是一种基于卷积LSTM编码层和LSTM解码层,并辅助注意力机制的端到端深度学习模型,可以自适应地学习与城市交通流相关的多通道多变量时空序列数据中的时空依赖性和非线性相关性特征.基于3个真实的交通流数据集实验结果表明:不管是单步预测还是多步预测条件下,STATF模型都具有更优的预测性能.

关键词：交通流预测长短时记忆网络序列到序列学习时空注意力编码器-解码器

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扩展乘数法与无界函数的多項式逼近(Ⅳ)——关于拟局部正线性算子的收斂性

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吉林大学自然科学学报 1965年第1期 31-43页

作者：王仁宏

本文基于对Hermite-Fejér插值多項式和拟Hermite-Fejér插值多項式的分析,引进了所謂拟局部正綫性算子。並在[1]-[5]的基础上,对这类新的更为一般的算子建立了扩展系数法的一般原则(参看定理1)。定理1概括了[1]-[5]中几乎所有的有关收... 详细信息

本文基于对Hermite-Fejér插值多項式和拟Hermite-Fejér插值多項式的分析,引进了所謂拟局部正綫性算子。並在[1]-[5]的基础上,对这类新的更为一般的算子建立了扩展系数法的一般原则(参看定理1)。定理1概括了[1]-[5]中几乎所有的有关收斂性方面的結果。§2,§3和§4主要是将定理1应用于以Jacobi多項式的根为节点的(通常的和拟的)Hermite-Fejér插值多項式和一类較簡明的近似多項式,得到了它們在整个实軸上对无界連續函数的可逼近性質。§5中还顺便指出了[1]中定理2的条件不仅是充分的而且也是必要的。

关键词：定理无界函数乘数蔽明插值多项式正算子收斂

Benign esophageal lesions: Endoscopic and pathologic features

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World Journal of Gastroenterology 2015年第4期21卷 1091-1098页

作者： Shu-Jung Tsai Ching-Chung Lin Chen-Wang Chang Chien-Yuan Hung Tze-Yu Shieh horng-Yuan Wang Shou-Chuan Shih Ming-Jen Chen Division of Gastroenterology Department of Internal MedicineMackay Memorial Hospital Department of Nursing Nursing and Management Mackay Junior College of Medicine Mackay Medical College

Benign esophageal lesions have a wide spectrum of clinical and pathologic features. Understanding the endoscopic and pathologic features of esophageal lesions is essential for their detection, differential diagnosis, and management. The purpose of this review is to provide updated features that may help physicians to appropriately manage these esophageal lesions. The endoscopic features of 2997 patients are reviewed. In epithelial lesions, the frequency of occurrence was in the following order: glycogenic acanthosis, heterotopic gastric mucosa, squamous papilloma, hyperplastic polyp, ectopic sebaceous gland and xanthoma. In subepithelial lesions, the order was as follows: hemangioma, leiomyoma, dysphagia aortica and granular cell tumor. Most benign esophageal lesions can be diagnosed according to their endoscopic appearance and findings on routine biopsy, and submucosal lesions, by endoscopic resection. Management is generally based upon the confidence of diagnosis and whether the lesion causes symptoms. We suggest endoscopic resection of all granular cell tumors and squamous papillomas because, while rare, these lesions have malignant potential. Dysphagia aortica should be considered in the differential diagnosis of dysphagia in the elderly.

关键词： Benign tumor Esophagus Epithelial lesions Subepith