检索结果-南通市图书馆

Surgical Repair of Ventricular Septal Defect in Neonates: Indications and Outcomes

Congenital Heart Disease 2024年第1期19卷 69-83页

作者： Jae Hong Lee Sungkyu Cho Jae Gun Kwak Hye Won kwon Woong-Han Kim Mi Kyoung Song Sang-Yun Lee Gi Beom Kim Eun Jung Bae Department of Thoracic and Cardiovascular Surgery Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalYangsanKorea Department of Thoracic and Cardiovascular Surgery Seoul National University Children’s HospitalSeoulKorea Department of Pediatrics Seoul National University Children’s HospitalSeoulKorea

Background:The optimal surgical timing and clinical outcomes of ventricular septal defect(VSD)closure in neo-nates remain *** aimed to evaluate the clinical outcomes of VSD closure in neonates(age≤30 days).Methods:We retrospectively reviewed 50 consecutive neonates who underwent VSD closure for isolated VSDs between August 2003 and June *** for the procedure included congestive heart failure/failure to thrive and pulmonary *** adverse events(MAEs)were deﬁned as the composite of all-cause mortality,reoperation,persistent atrioventricular block,and signiﬁcant(≥grade 2)valvular ***:The median age and body weight at operation were 26.0 days(interquartile range[IQR],18.8–28.3)and 3.7 kg(IQR,3.3–4.2),*** median follow-up duration was 110.4 months(IQR,56.8–165.0).Seven patients required preoperative respiratory support,andﬁve had signiﬁcant(≥grade 2)preoperative valvular *** early mortality occurred due to irreversible cardiogenic shock;no late mortality was *** reopera-tion was due to hemodynamically signiﬁcant residual VSD at 103.8 months *** overall survival,freedom from reoperation,and freedom from MAE at 15-years were 98.0%,96.3%,and 94.4%,***-operative mechanical ventilation was associated with a longer duration of postoperative mechanical ventilation(p<0.001)and a longer length of intensive care unit stay(p<0.001).Conclusions:VSD closure with favorable outcomes without morbidities is feasible even in ***,neonates requiring preoperative respiratory support may require careful postoperative management considering the long-term postoperative ***,surgical VSD closure might be indicated earlier in neonates with respiratory compromise.

关键词： Ventricular septal defect neonate early surgery neonatal surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of atractylenolide Ⅲ on zearalenone-induced Snail1-mediated epithelial–mesenchymal transition in porcine intestinal epithelium

引用

Journal of Animal Science and Biotechnology 2024年第05期 2081-2092页

作者： Na Yeon Kim Myoung Ok Kim Sangsu Shin Woo-Sung kwon Bomi Kim Joon Yeop Lee Sang In Lee Department of Animal Science and Biotechnology Kyungpook National University Research Institute for Innovative Animal Science Kyungpook National University National Institute for Korean Medicine Development

Background The intestinal epithelium performs essential physiological functions, such as nutrient absorption, and acts as a barrier to prevent the entry of harmful substances. Mycotoxins are prevalent contaminants found in ani-mal feed that exert harmful effects on the health of livestock. Zearalenone(ZEA) is produced by the Fusarium genus and induces gastrointestinal dysfunction and disrupts the health and immune system of animals. Here, we evaluated the molecular mechanisms that regulate the effects of ZEA on the porcine intestinal *** Treatment of IPEC-J2 cells with ZEA decreased the expression of E-cadherin and increased the expression of Snai1 and Vimentin, which induced Snail1-mediated epithelial-to-mesenchymal transition(EMT). In addition, ZEA induces Snail-mediated EMT through the activation of TGF-β signaling. The treatment of IPEC-J2 cells with atractyle-nolide Ⅲ, which were exposed to ZEA, alleviated *** Our findings provide insights into the molecular mechanisms of ZEA toxicity in porcine intestinal epi-thelial cells and ways to mitigate it.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Computation and field experiment validation of greenhouse energy load using building energy simulation model

引用

International Journal of Agricultural and Biological Engineering 2015年第6期8卷 116-127页

作者： Taehwan Ha In-bok Lee kyeong-seok kwon Se-Woon Hong College of Agriculture and Life Sciences Seoul National University1 Gwanak-roGwanak-guSeoul 151-921Korea Research Institute of Agriculture and Life Sciences 1 Gwanak-roGwanak-guSeoul 151-921Korea Institute for Agricultural and Fisheries Research(ILVO) Burg.Van Gansberghelaan 1159820 MerelbekeBelgium

Greenhouse Building Energy Simulation(BES)models were developed to estimate the energy load using TRNSYS(ver.16,University of Wisconsin,USA),a commercial BES *** was conducted based on data recorded during field *** BES greenhouse modeling is reliable,as validation showed 5.2%and 5.5%compared with two field experiments,*** the next step,the heating characteristics of the greenhouses were analyzed to predict the maximum and annual total heating loads based on the greenhouse types and target locations in the Republic of Korea using the validated greenhouse *** BES-computed results indicated that the annual heating load was greatly affected by the local climate conditions of the target *** annual heating load of greenhouses located in Chuncheon,the northernmost region,was 44.6%higher than greenhouses in Jeju,the southernmost area among the studied *** regression models for prediction of maximum heating load of Venlo type greenhouse and widespan type greenhouse were developed based on the BES computed results to easily predict maximum heating load at field and they explained nearly 95%and 80%of the variance in the data set used,respectively,with the predictor *** a BES model of geothermal energy system was additionally designed and incorporated into the BES greenhouse *** feasibility of the geothermal energy system for greenhouse was estimated through economic analysis.

关键词： Greenhouse building energy simulation(BES) energy load dynamic analysis geothermal energy heating load

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimal rotor wear design in hypotrochoidal gear pump using genetic algorithm

引用

Journal of Central South University 2011年第3期18卷 718-725页

作者： kwon soon-man KIM Chang-Hyun SHIN Joong-ho Department of Mechanical Design and Manufacturing Engineering Changwon National University

The wear rate between the rotors of a hypotrochoidal gear pump is *** the knowledge of shape design on the rotors,the contact stresses without hydrodynamic effect between the rotor teeth were evaluated through the calculation of the Hertzian contact *** on the above results and the sliding velocity between the rotors,a genetic algorithm (GA) was used as an optimization technique forminimizing the wear rate proportional factor (WRPF).The result shows that the wear rate or the WRPF can be reduced considerably,*** 12.8%,throughout the optimization using GA.

关键词： gerotor hypotrochoidal gear pump Hertzian contact stress wear rate proportional factor genetic algorithm

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Changes in microorganisms and metabolites during long-term fermentation of commercially manufactured anchovy sauce

引用

Food Science and Human Wellness 2024年

作者： Daehyeon Kim Seong-Eun Park Eun-Ju Kim Seung-Ho Seo Kwang-Moon Cho Sun Jae kwon Hong-Seok Son Department of Biotechnology， College of Life Sciences and Biotechnology， Korea University Sonlab Inc. 3. AccuGene Inc.

This study was performed to investigate the changes in microbial communities and metabolites during the long-term fermentation of commercially manufactured anchovy sauce. Samples of commercial anchovy sauce were collected from large-scale fermentation tanks with fermentation periods of up to 7.87 years. The complex bacterial community was simplified to two genera， Tetragenococcus and Halanaerobium， after approximately 0.55 years of fermentation. Although genera， such as Saccharomyces， Cladosporium， Candida， and Aspergillus， were relatively dominant， no clear pattern was identified in fungal community analysis. The longitudinal metabolite profile demonstrated that approximately half (55.8%) of the metabolites present in anchovy sauce were produced within a year of fermentation due to rapid fermentation. Despite the static microbial community， the contents of several metabolites including amino acids and biogenic amines changed continuously during the long-term fermentation of anchovy sauce. This study provides novel insights into the changes in microbiota and metabolites in fish sauce produced without any starter inoculation.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Kinematical system of breadth cam profile design

引用

Journal of Central South University 2011年第2期18卷 451-457页

作者： SHIN Joong-ho 李琳 YANG Hyun-dai kwon soon-man Department of Mechanical Design & Manufacturing Changwon National University

The design solutions for breadth cam mechanism was presented. The main topics of the shape design for breadth cam was to calculate the coordinate at each contact point to determine the cam profile. The proposed method according to velocity and geometric relationships of instant velocity centers can easily determine each contact point at any instant moment. The cam profile was defined by contouring of the contact points. And also a program was developed by using Microsoft Visual C++ program,which can quickly and easily draw a 2D cam profile through the displacement diagram. Finally,the program was used to confirm the accuracy on the breadth cam profile design by computer animation graphically.

关键词： cam profile breadth cam reciprocating follower oscillating follower instant velocity center

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Capsosiphon fulvescens suppresses LPS-stimulated inflammatory responses by suppressing TLR4/NF-κB activation in RAW264.7 murine macrophages

引用

Asian Pacific Journal of Tropical Biomedicine 2024年第3期14卷 115-126页

作者： Seon Yeong Ji EunJin Bang Hyun Hwangbo Min Yeong Kim Da Hye Kim Su Hyun Hong Shin-Hyung Park Chang-Young kwon Gi-Young Kim You-Jin Jeon Suengmok Cho Yung Hyun Choi Department of Biochemistry Dong-eui University College of Korean MedicineBusan 47227Republic of Korea Basic Research Laboratory for the Regulation of Microplastic-Mediated Diseases and Anti-Aging Research Center Dong-eui UniversityBusan 47227Republic of Korea Department of Pathology Dong-eui University College of Korean MedicineBusan 47227Republic of Korea Department of Oriental Neuropsychiatry Dong-eui University College of Korean MedicineBusan 47227Republic of Korea Department of Marine Life Science Jeju National UniversityJeju 63243Republic of Korea Department of Food Science and Technology/Institute of Food Science Pukyong National UniversityBusan 48513Republic of Korea

Objective:To evaluate the effects of Capsosiphon fulvescens(***)ethanolic extract on inflammation in lipopolysaccharide(LPS)-induced RAW296.7 ***:The protective effects of *** ethanolic extract on LPS-induced inflammation in RAW264.7 macrophages were assessed using biochemical analysis,including enzyme-linked immunosorbent assay,quantitative reverse transcription-polymerase chain reaction,and Western blot *** examine reactive oxygen species(ROS)production,flow cytometry analysis,and immunofluorescence staining were ***,the modulatory effect of *** ethanolic extract on NF-κB activation was ***:*** ethanolic extract significantly attenuated LPS-induced levels of pro-inflammatory cytokines and notably reduced the secretion and mRNA levels of LPS-mediated matrix *** addition,*** ethanolic extract decreased ROS production and suppressed the TLR4/NF-κB signaling ***:*** ethanolic extract alleviates inflammation as well as oxidative stress by modulating the TLR4/NF-κB signaling in LPS-induced RAW264.7 *** can be used as a potential therapeutic agent to suppress inflammation and oxidative stress-associated diseases.

关键词： Capsosiphon fulvescens Inflammation Oxidative stress NF-κB Nrf2 TLR4

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Survival benefit of concurrent chemoradiotherapy for advanced ampulla of Vater cancer

引用

World Journal of Clinical Cases 2024年第2期12卷 267-275页

作者： Chae Hwa kwon Hyung Il Seo Dong Uk Kim Sung Yong Han Suk Kim Nam Kyung Lee Seung Baek Hong Ji Hyun Ahn Young Mok Park Byeong Gwan Noh BioMedical Research Institute Pusan National University HospitalBusan 49241South Korea Department of Surgery Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Internal Medicine Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Radiology Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Pathology and Biomedical Research Institute Pusan National University HospitalBusan 49241South Korea

BACKGROUND Currently,there is no standard adjuvant therapy for patients with resected ampulla of Vater(AoV)*** To evaluate the effectiveness of adjuvant concurrent chemoradiotherapy(CCRT)in patients with advanced AoV cancer who underwent curative *** This single-centered,retrospective study included 29 patients with advanced AoV cancer who underwent pancreaticoduodenectomy between 2006 and *** impact of CCRT on advanced AoV cancer was *** The 1-,3-,and 5-yr recurrence-free survival(RFS)rates for patients with advanced AoV cancer were 82.8%,48.3%,and 40.8%,respectively,and the overall survival(OS)rates were 89.7%,62.1%,and 51.7%,***-cular invasion was found to be a significant risk factor for RFS and OS in patients with advanced AoV cancer in the univariate analysis,whereas T stage and lymph node metastasis were significantly associated with OS in the multivariate *** to the patients who did not receive adjuvant CCRT,those who received adjuvant CCRT did not show statistically significant improvements in the RFS and OS,although they had a significantly lower average age and significantly higher platelet-to-lymphocyte *** Adjuvant CCRT did not improve survival outcomes in patients with advanced AoV *** findings contribute to existing knowledge on the effectiveness of CCRT in this patient population and provide important insights for clinical decision-making.

关键词： Advanced ampulla of Vater cancer Adjuvant concurrent chemoradiotherapy Recurrence Survival Vater cancer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cell architecture designs towards high-energy-density microscale energy storage devices

引用

Nano Research Energy 2024年第2期3卷 69-82页

作者： kwon-Hyung Lee Sang-Young Lee Ulsan Advanced Energy Technology R&D Center Korea Institute of Energy Research(KIER)Ulsan44776Republic of Korea Department of Chemical and Biomolecular Engineering Yonsei UniversitySeoul03722Republic of Korea

The rapid growth of miniaturized electronics has led to an urgent demand for microscale energy storage devices(MESDs)to sustainably power the micro electronic ***,most MESDs reported to date have suffered from the limited energy densities and shape versatility compared to conventional large-scale counterparts because of the architectural constraints inherent in microfabrication-based cell manufacturing and cell dimension/*** review addresses the cell architecture design for MESDs that can achieve both miniaturization and high energy *** provide a comprehensive overview of five types of cell architectures of MESDs and their fabrication *** addition,to enable practical applications of MESDs,several cell design approaches are presented with the aim of minimizing the inactive parts of the cell and maximizing the performance metrics of ***,we discuss development direction and outlook of MESDs with a focus on materials chemistry,energy-dense electrochemical systems,and cell performance normalization,which will help to expand their applications and manufacturing scalability.

关键词： microscale energy storage device cell architecture microfabrication miniaturization high-energy-density

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preparation of AZ91D Slurries for Semi-Solid Forming Using Al8 ( Mn, Fe) 5 Precipitates

引用

Journal of Rare Earths 2004年第z2期22卷 42-46页

作者： Ji Young Byun soon Il kwon Jeong Man Doh Heon Phil Ha Metal Processing Research Center Division of MaterialsKorea Institute of Science and Technology# 39-1 Haweolgok-DongSungbuk-KuSeoul 136-791Republic of Korea

During the solidification of the AZ91D-alloys, the Al8(Mn, Fe)5 phase is generally precipitated in the melt in advance of the precipitation of the primary α-Mg. The basic principle for manufacturing AZ91D-alloy slurries for semi solid forming is to use the Al8(Mn, Fe)5 precipitates as the heterogeneous nucleation sites for primary α-Mg phases. Microscopic analysis for the location of the Al8(Mn, Fe)5 precipitate explains that the Al8(Mn, Fe)5 precipitate is the effective heterogeneous nucleation site for the primary α-Mg phase. It was also observed that increase of the Mn content in the melt and the cooling rate below to the solid/liquid two-phase region resulted in smaller and more globular primary α-Mg due to the increase of heterogeneous nucleation sites. It was found that the average α-Mg diameter grew as a function of t0.278, where t is the holding time at the solid/liquid two-phase region. This would be attributed to the Ostwald type ripening and coalescence between primary α-Mg phases. The cooling rate below to the solid/liquid two-phase region, Mn content in AZ91D alloy, and the holding time and temperature affected on the quality of slurry.

关键词： AZ91D alloy semi-solid forming solidification heterogeneous nucleation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：